Alexander S. Hebert

发表

A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis.

Derek J. Bailey, Derek J Bailey, Joshua J Coon, 2012, Cell metabolism.

Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

Nicholas W. Kwiecien, Paul D Hutchins, Kyle P. Robinson, 2016, Nature Biotechnology.

Gas-phase purification enables accurate, large-scale, multiplexed proteome quantification with isobaric tagging

M. Westphall, G. McAlister, J. Coon, 2011, Nature Methods.

The One Hour Yeast Proteome*

Derek J. Bailey, M. Westphall, J. Coon, 2013, Molecular & Cellular Proteomics.

A Molecular Portrait of De Novo Genes in Yeasts

G. Fischer, J. Coon, G. Achaz, 2018, Molecular biology and evolution.

A Molecular Portrait Of De Novo Genes

G. Fischer, J. Coon, G. Achaz, 2017 .

Yeast de novo genes preferentially emerge from divergently transcribed, GC-rich intergenic regions

G. Fischer, J. Coon, G. Achaz, 2017, bioRxiv.

The Negative Mode Proteome with Activated Ion Negative Electron Transfer Dissociation (AI-NETD)*

Derek J. Bailey, Joshua J. Coon, Michael S. Westphall, 2015, Molecular & Cellular Proteomics.

Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis

Nicholas M Riley, Joshua J Coon, M. Westphall, 2019, Nature Communications.

One-hour proteome analysis in yeast

Derek J. Bailey, Derek J Bailey, Joshua J Coon, 2015, Nature Protocols.

Expression of novel “LOCGEF” isoforms of ARHGEF18 in eosinophils

J. Coon, Emily M. Wilkerson, D. Mosher, 2018, Journal of leukocyte biology.

Amine-reactive Neutron-encoded Labels for Highly Plexed Proteomic Quantitation*

Derek J. Bailey, Joshua J. Coon, Michael S. Westphall, 2013, Molecular & Cellular Proteomics.

Now, More Than Ever, Proteomics Needs Better Chromatography.

Evgenia Shishkova, Joshua J. Coon, J. Coon, 2016, Cell systems.

OptSSeq explores enzyme expression and function landscapes to maximize isobutanol production rate.

J. Coon, R. Landick, Alexander S. Hebert, 2019, Metabolic engineering.

Ultra-High Pressure (>30,000 psi) Packing of Capillary Columns Enhancing Depth of Shotgun Proteomic Analyses.

M. Westphall, J. Coon, E. Shishkova, 2018, Analytical chemistry.

Chemical genomic guided engineering of gamma-valerolactone tolerant yeast

C. Myers, J. Coon, J. Piotrowski, 2017, bioRxiv.

Chemical genomic guided engineering of gamma-valerolactone tolerant yeast

C. Myers, J. Coon, J. Piotrowski, 2017, bioRxiv.

Analysis of the acidic proteome with negative electron-transfer dissociation mass spectrometry.

M. Westphall, G. McAlister, J. Coon, 2012, Analytical chemistry.

Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis

M. Westphall, J. Coon, Alexander S. Hebert, 2019, bioRxiv.

A map of the phosphoproteomic alterations that occur after a bout of maximal‐intensity contractions

M. Westphall, J. Coon, T. Hornberger, 2017, The Journal of physiology.

Gender Diversity in a STEM Subfield – Analysis of a Large Scientific Society and Its Annual Conferences

Nicholas W. Kwiecien, M. Westphall, J. Coon, 2017, Journal of The American Society for Mass Spectrometry.

Heterologous expression of a glycosyl hydrolase and cellular reprogramming enable Zymomonas mobilis growth on cellobiose

J. Coon, R. Landick, Alexander S. Hebert, 2020, PloS one.

Proteomic and Phosphoproteomic Changes Induced by Prolonged Activation of Human Eosinophils with IL-3.

N. Jarjour, J. Coon, S. Esnault, 2018, Journal of proteome research.

Proteomics of Eosinophil Activation

J. Coon, Emily M. Wilkerson, D. Mosher, 2017, Front. Med..

Genome Wide Phosphoproteome Analysis of Zymomonas mobilis Under Anaerobic, Aerobic, and N2-Fixing Conditions

J. Coon, M. Tatli, Alexander S. Hebert, 2019, Front. Microbiol..

Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family.

Paul D Hutchins, Jaime L. Stark, J. Markley, 2017, Cell chemical biology.

Complete genome sequenc e and the expression patter n of plasmids of the model ethanologen Zymomonas mobilis ZM 4 and its xylose-utilizing derivativ es 8 b and 2032

M. Himmel, J. Coon, Min Zhang, 2018 .

The Peripheral Blood Eosinophil Proteome.

M. Westphall, N. Jarjour, J. Coon, 2016, Journal of proteome research.

Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition

Nicholas W. Kwiecien, J. Coon, Wei Xu, 2017, Nature Communications.

Multi-Omic Single-Shot Technology for Integrated Proteome and Lipidome Analysis.

M. Westphall, J. Coon, D. Pagliarini, 2020, Analytical chemistry.

Tomosyn-2 De-represses Insulin Secretion Phosphorylation and Degradation of Signal Transduction :

A. Attie, J. Coon, Mark P. Keller, 2014 .

Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion*

A. Attie, J. Coon, Mark P. Keller, 2014, The Journal of Biological Chemistry.

NeuCode Labels for Relative Protein Quantification* □ S

Derek J. Bailey, A. Gasch, M. Westphall, 2014 .

Defining mitochondrial protein functions through deep multiomic profiling

Mark W. Craven, Dain R. Brademan, Nicholas W. Kwiecien, 2022, Nature.

Genome-Scale Transcription-Translation Mapping Reveals Features of Zymomonas mobilis Transcription Units and Promoters

J. Coon, R. Landick, Alexander S. Hebert, 2020, mSystems.

Global Phosphoproteome Analysis Using FAIMS on a Hybrid Orbitrap Mass Spectrometer

M. Westphall, J. Coon, Alexander S. Hebert, 2021 .

Heterologous glycosyl hydrolase expression and cellular reprogramming resembling sucrose-induction enable Zymomonas mobilis growth on cellobiose

J. Coon, R. Landick, Alexander S. Hebert, 2019, bioRxiv.

Improved Precursor Characterization for Data-Dependent Mass Spectrometry.

Nicholas W. Kwiecien, M. Westphall, G. McAlister, 2018, Analytical chemistry.

Tcof1 haploinsufficiency promotes early T cell precursor-like leukemia in NrasQ61R/+ mice

E. Ranheim, Menggang Yu, J. Coon, 2022, Leukemia.

A Split-Abl Kinase for Direct Activation in Cells.

Joshua J Coon, J. Coon, J. E. Díaz, 2017, Cell chemical biology.

High-resolution filtering for improved small molecule identification via GC/MS.

Derek J. Bailey, Nicholas W. Kwiecien, M. Westphall, 2015, Analytical chemistry.

Multiomic Fermentation Using Chemically Defined Synthetic Hydrolyzates Revealed Multiple Effects of Lignocellulose-Derived Inhibitors on Cell Physiology and Xylose Utilization in Zymomonas mobilis

J. Coon, R. Landick, Dan Xie, 2019, Front. Microbiol..

Complete genome sequence and the expression pattern of plasmids of the model ethanologen Zymomonas mobilis ZM4 and its xylose-utilizing derivatives 8b and 2032

Sean J McIlwain, Min Zhang, Shihui Yang, 2018, Biotechnology for Biofuels.

Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability.

M. Rodgers, Alexander S. Hebert, A. Drohat, 2006, Journal of the American Chemical Society.

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.

Wei Yu, Sushmita Roy, Derek J. Bailey, 2013, Molecular cell.

Global Phosphoproteome Analysis Using High-Field Asymmetric Waveform Ion Mobility Spectrometry on a Hybrid Orbitrap Mass Spectrometer.

M. Westphall, J. Coon, E. Shishkova, 2020, Analytical chemistry.

Comprehensive Single-Shot Proteomics with FAIMS on a Hybrid Orbitrap Mass Spectrometer.

Susan E. Abbatiello, Derek J. Bailey, M. Westphall, 2018, Analytical chemistry.

NeuCode Labels for Relative Protein Quantification *

Christopher M Rose, Derek J. Bailey, Audrey P Gasch, 2014, Molecular & Cellular Proteomics.

NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.

M. Westphall, J. DeVoss, A. Attie, 2016, Cell reports.

NrasQ61R/+ and Kras−/− cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors

E. Ranheim, Alexander S. Hebert, J. Roose, 2021, Blood.

Single-Shot Capillary Zone Electrophoresis-Tandem Mass Spectrometry Produces Over 4400 Phosphopeptide Identifications from 220 ng Sample.

M. Westphall, J. Coon, N. Dovichi, 2019, Journal of proteome research.

Ribonucleic acid sequence characterization by negative electron transfer dissociation mass spectrometry.

Dain R. Brademan, M. Westphall, J. Coon, 2020, Analytical chemistry.

Capturing site-specific heterogeneity with large-scale N-glycoproteome analysis

M. Westphall, J. Coon, Alexander S. Hebert, 2019, bioRxiv.

Implementation of Activated Ion Electron Transfer Dissociation on a Quadrupole-Orbitrap-Linear Ion Trap Hybrid Mass Spectrometer.

M. Westphall, J. Coon, Alexander S. Hebert, 2017, Analytical chemistry.

Phosphoproteomics with Activated Ion Electron Transfer Dissociation.

M. Westphall, K. Mechtler, J. Coon, 2017, Analytical chemistry.

Coupling capillary zone electrophoresis with electron transfer dissociation and activated ion electron transfer dissociation for top-down proteomics.

M. Westphall, J. Coon, N. Dovichi, 2015, Analytical chemistry.

The negative mode proteome with AI-NETD 1 The Negative Mode Proteome with Activated Ion Negative Electron Transfer Dissociation

Derek J. Bailey, M. Westphall, Alexander S. Hebert, 2015 .

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.

Nicholas W. Kwiecien, Paul D Hutchins, M. Westphall, 2016, Molecular cell.

Valosin-containing protein (VCP)–Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor *

Justin M. Reitsma, R. Deshaies, J. Coon, 2016, Molecular & Cellular Proteomics.

Erythropoietin signaling regulates heme biosynthesis

B. Paw, H. Lodish, S. Orkin, 2016, eLife.

Proteomic Atlas of the Human Brain in Alzheimer's Disease.

S. Salamat, J. Coon, Alexander S. Hebert, 2019, Journal of proteome research.

A Genetic Toggle for Chemical Control of Individual Plk1 Substrates.

M. Burkard, J. Coon, B. Weaver, 2020, Cell chemical biology.

Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development

Elizabeth H. Peuchen, J. Coon, N. Dovichi, 2017, Scientific Reports.

Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans.

Icksoo Lee, Xiaowu Gai, Satish Srinivasan, 2014, Journal of molecular biology.

Neutron-encoded mass signatures for multi-plexed proteome quantification

Derek J. Bailey, Derek J Bailey, Joshua J Coon, 2013, Nature Methods.

Genome-Scale Transcription-Translation Mapping Reveals Features of Zymomonas mobilis Transcription Units and Promoters

J. Coon, Alexander S. Hebert, Yaoping Zhang, 2020 .

Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae

Kevin S. Myers, A. Gasch, J. Reed, 2016, PLoS genetics.

Mechanism of imidazolium ionic liquids toxicity in Saccharomyces cerevisiae and rational engineering of a tolerant, xylose-fermenting strain

Sheena C. Li, C. Myers, Charles Boone, 2016, Microbial Cell Factories.

Systems-Level Analysis of Oxygen Exposure in Zymomonas mobilis: Implications for Isoprenoid Production

J. Coon, Alexander S. Hebert, D. Stevenson, 2019, mSystems.

Multiplexed quantification for data-independent acquisition.

M. Westphall, J. Coon, D. Pagliarini, 2015, Analytical chemistry.

Molecular anatomy of eosinophil activation by IL5 and IL33

Joshua M. Mitchell, J. Coon, D. Mosher, 2022, bioRxiv.

Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion

Nicholas W. Kwiecien, A. Attie, K. Schueler, 2018, The Journal of Biological Chemistry.

GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.

Colin N. Dewey, S. Keleş, J. Coon, 2017, Developmental cell.

Metabolic Remodeling during Nitrogen Fixation in Zymomonas mobilis

J. Coon, Alexander S. Hebert, Tyler B. Jacobson, 2021, mSystems.

Neutron-Encoded Mass Signatures for Quantitative Top-Down Proteomics∥

Lloyd M. Smith, Derek J. Bailey, B. Garcia, 2014, Analytical chemistry.

Quantification of Mitochondrial Acetylation Dynamics Highlights Prominent Sites of Metabolic Regulation*

M. Westphall, A. Attie, J. Coon, 2013, The Journal of Biological Chemistry.

Systematic Analysis of Metabolic Bottlenecks in the Methylerythritol 4-Phosphate (MEP) Pathway of Zymomonas mobilis

J. Coon, Alexander S. Hebert, D. Amador-Noguez, 2023, mSystems.

Global detection of human variants and isoforms by deep proteome sequencing

Robert J. Weatheritt, Dain R. Brademan, B. Blencowe, 2023, Nature Biotechnology.

Proteomics Moves into the Fast Lane.

J. Coon, Alexander S. Hebert, N. Riley, 2016, Cell systems.

ID-MAM: A Validated Identity and Multi-Attribute Monitoring Method for Commercial Release and Stability Testing of a Bispecific Antibody.

M. Lewis, Alexander S. Hebert, A. Evans, 2021, Analytical chemistry.

Multiplexed proteome analysis with neutron-encoded stable isotope labeling in cells and mice

J. Cox, M. Westphall, J. Coon, 2018, Nature Protocols.

Quantitative capillary zone electrophoresis-mass spectrometry reveals the N-glycome developmental plan during vertebrate embryogenesis.

Elizabeth H. Peuchen, J. Coon, N. Dovichi, 2020, Molecular omics.

HIV-1 virological synapse formation enhances infection spread by dysregulating Aurora Kinase B

Chris S. Magnano, P. Ahlquist, J. Coon, 2023, PLoS pathogens.

Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development

Elizabeth H. Peuchen, J. Coon, N. Dovichi, 2017, Scientific Reports.

Over 10,000 peptide identifications from the HeLa proteome by using single-shot capillary zone electrophoresis combined with tandem mass spectrometry.

Liangliang Sun, Guijie Zhu, Joshua J Coon, 2014, Angewandte Chemie.

Neucode Labels for Multiplexed, Absolute Protein Quantification.

Derek J. Bailey, M. Westphall, J. Coon, 2016, Analytical chemistry.

Protein Composition of Infectious Spores Reveals Novel Sexual Development and Germination Factors in Cryptococcus

J. Coon, Alexander S. Hebert, Mingwei Huang, 2015, PLoS genetics.

Correction: Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae

Kevin S. Myers, A. Gasch, J. Reed, 2016, PLoS Genetics.

Production of Over 27 000 Peptide and Nearly 4400 Protein Identifications by Single-Shot Capillary-Zone Electrophoresis-Mass Spectrometry via Combination of a Very-Low-Electroosmosis Coated Capillary, a Third-Generation Electrokinetically-Pumped Sheath-Flow Nanospray Interface, an Orbitrap Fusion Lu

Yanyan Qu, Joshua J Coon, M. Westphall, 2018, Analytical chemistry.

Author response: Erythropoietin signaling regulates heme biosynthesis

B. Paw, H. Lodish, S. Orkin, 2017 .

Valosin-containing protein (VCP)–Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor *

Justin M. Reitsma, R. Deshaies, J. Coon, 2016, Molecular & Cellular Proteomics.

Quantification of Mitochondrial Acetylation Dynamics Highlights Prominent Sites of Metabolic Regulation*

M. Westphall, A. Attie, J. Coon, 2013, The Journal of Biological Chemistry.

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.

Derek J. Bailey, T. Prolla, M. Westphall, 2013, Molecular cell.

Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.

Nicholas W. Kwiecien, Paul D Hutchins, M. Westphall, 2016, Molecular cell.

Comprehensive Single-Shot Proteomics with FAIMS on a Hybrid Orbitrap Mass Spectrometer.

Susan E. Abbatiello, Derek J. Bailey, Dain R. Brademan, 2018, Analytical chemistry.

Phosphorothioate RNA Analysis by NETD Tandem Mass Spectrometry

M. Westphall, J. Coon, J. Syka, 2024, Molecular & cellular proteomics : MCP.