N. Santesso

H. Schünemann, R. Mustafa, N. Santesso, 2016, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

A summary to communicate evidence from systematic reviews to the public improved understanding and accessibility of information: a randomized controlled trial.

Sarah E. Rosenbaum, T. Rader, H. Schünemann, 2015, Journal of clinical epidemiology.

GRADE guidelines: 21 part 2. Inconsistency, Imprecision, publication bias and other domains for rating the certainty of evidence for test accuracy and presenting it in evidence profiles and summary of findings tables.

G. Guyatt, P. Bossuyt, L. Hooft, 2020, Journal of clinical epidemiology.

Integrated multidisciplinary care for the management of chronic conditions in adults: an overview of reviews and an example of using indirect evidence to inform clinical practice recommendations in the field of rare diseases

H. Schünemann, A. Iorio, N. Santesso, 2016, Haemophilia : the official journal of the World Federation of Hemophilia.

Knowledge translation in developing countries

P. Tugwell, N. Santesso, 2006, The Journal of continuing education in the health professions.

The Rx for Change database: a first-in-class tool for optimal prescribing and medicines use

J. Grimshaw, A. Mayhew, S. Hill, 2010, Implementation science : IS.

A practical guide for using a survey about attitudes and behaviours to inform health care decisions.

G. Guyatt, D. Cook, M. Bhandari, 2020, Journal of clinical epidemiology.

GRADE guidance 24 optimizing the integration of randomized and non-randomized studies of interventions in evidence syntheses and health guidelines

G. Guyatt, E. Akl, H. Schünemann, 2021, Journal of clinical epidemiology.

GRADE approach to drawing conclusions from a network meta-analysis using a partially contextualised framework

G. Guyatt, H. Schünemann, B. Rochwerg, 2020, BMJ.

Methods used in adaptation of health–related guidelines: A systematic survey

Rima A. Abdul-Khalek, E. Akl, H. Schünemann, 2017, Journal of global health.

Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise

Romina Brignardello-Petersen, Gordon H. Guyatt, Reem A. Mustafa, 2014, Canadian Medical Association Journal.

Patient engagement in clinical guidelines development: input from > 1000 members of the Canadian Osteoporosis Patient Network

W. Leslie, L. Giangregorio, I. Rodrigues, 2019, Osteoporosis International.

The cost-effectiveness of 10 antenatal syphilis screening and treatment approaches in Peru, Tanzania, and Zambia

R. Peeling, C. Watts, L. Newman, 2015, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Interactive Summary of Findings tables: the way to present and understand results of systematic reviews.

H. Schünemann, J. Brożek, N. Santesso, 2019, JBI database of systematic reviews and implementation reports.

Building Health‐Literate Societies

S. Hill, Chaojie Liu, N. Santesso, 2011 .

An instrument to assess quality of life in relation to nutrition: item generation, item reduction and initial validation

G. Guyatt, E. Akl, H. Schünemann, 2010, Health and quality of life outcomes.

GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings.

G. Guyatt, H. Schünemann, M. Murad, 2021, Journal of clinical epidemiology.

GRADE: Assessing the quality of evidence in environmental and occupational health.

Nancy Santesso, Ellen K Silbergeld, Eva A Rehfuess, 2016, Environment international.

Psychosocial interventions for responding to child sexual abuse: A systematic review.

D. Fitzpatrick-Lewis, H. MacMillan, N. Santesso, 2019, Child abuse & neglect.

Recommendations for antibiotic prescriptions for upper respiratory symptoms in children in Trinidad and Tobago: GRADE-ADOLOPMENT APPROACH

N. Santesso, S. Giddings, L. Reveiz, 2020 .

Antivirals for Treatment of Influenza

H. Schünemann, J. Brożek, N. Santesso, 2012, Annals of Internal Medicine.

Improving Understandability of Clinical Practice Guideline Recommendations: a Qualitative Study to Develop a Format for Pediatric Cancer Care

N. Santesso, L. Dupuis, P. Robinson, 2021 .

Antivirals for influenza: a summary of a systematic review and meta‐analysis of observational studies

E. Akl, S. Flottorp, H. Schünemann, 2013, Influenza and other respiratory viruses.

How to use a patient management recommendation : : clinical practice guidelines and decision analyses

G. Guyatt, E. Akl, H. Schünemann, 2014 .

A Summary of a Cochrane Review: Acupuncture or acupressure for induction of labour.

N. Santesso, L. S. Wieland, 2018, European journal of integrative medicine.

Development of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Summary of Findings (SoF) Table for Network Meta-analysis.

G. Guyatt, L. Mbuagbaw, J. Beyene, 2019, Journal of clinical epidemiology.

Comparing the usability of the World Health Organization’s conventional tuberculosis guidelines to the eTB recommendations map: A two-arm superiority randomised controlled trial

M. Loeb, N. Santesso, T. Piggott, 2022, PLOS global public health.

Improving GRADE evidence tables part 3: detailed guidance for explanatory footnotes supports creating and understanding GRADE certainty in the evidence judgments.

Alonso Carrasco-Labra, Elie A Akl, Romina Brignardello-Petersen, 2016, Journal of clinical epidemiology.

Incorporating GRADE in Cochrane Reviews: Feedback from the CEU screening programme

T. Lasserson, R. Marshall, N. Santesso, 2014 .

Knowledge transfer to clinicians and consumers by the Cochrane Musculoskeletal Group.

P. Tugwell, R. Buchbinder, A. O'Connor, 2006, The Journal of rheumatology.

Table of Contents

S. Vesely, E. Akl, T. Ortel, 2019, Journal of Clinical Epidemiology.

Knowledge for knowledge translation: The role of the Cochrane Collaboration

Nancy Santesso, Alain Mayhew, Jeremy M Grimshaw, 2006, The Journal of continuing education in the health professions.

Fracture risk in long term care: a systematic review and meta-analysis of prospective observational studies

L. Giangregorio, A. Papaioannou, N. Santesso, 2014, BMC Geriatrics.

GRADE Guidelines: 16. GRADE evidence to decision frameworks for tests in clinical practice and public health.

Elie A Akl, Jan Brozek, Andrew D Oxman, 2016, Journal of clinical epidemiology.

Treatment of Neonatal Chlamydial Conjunctivitis: A Systematic Review and Meta-analysis

H. Schünemann, N. Santesso, T. Wi, 2018, Journal of the Pediatric Infectious Diseases Society.

A Summary of a Cochrane Review: Green and Black Tea for the Primary Prevention of Cardiovascular Disease

N. Santesso, E. Manheimer, 2014, Global Advances in Health and Medicine.

Diagnosing sexually transmitted infections in resource‐constrained settings: challenges and ways forward

M. Unemo, N. Santesso, C. Ferreyra, 2019, Journal of the International AIDS Society.

Effects of dance on cognitive function in older adults: a systematic review and meta-analysis.

P. Santaguida, D. Merom, L. Thabane, 2020, Age and ageing.

A Summary of a Cochrane Review: Ganoderma lucidum (Reishi mushroom) for the treatment of cancer.

N. Santesso, L. S. Wieland, 2016, European journal of integrative medicine.

Systematic reviews and meta‐analyses of the accuracy of HPV tests, visual inspection with acetic acid, cytology, and colposcopy

Reem A. Mustafa, Wojtek Wiercioch, Holger J. Schünemann, 2016, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Identifying children exposed to maltreatment: a systematic review update

H. MacMillan, N. Santesso, Jill R. McTavish, 2020, BMC Pediatrics.

Development of rapid guidelines: 1. Systematic survey of current practices and methods

Yuan Zhang, Wojtek Wiercioch, Holger J. Schünemann, 2018, Health Research Policy and Systems.

Effects of higher- versus lower-protein diets on health outcomes: a systematic review and meta-analysis

E. Akl, H. Schünemann, R. Mustafa, 2012, European Journal of Clinical Nutrition.

Cytology versus HPV testing for cervical cancer screening in the general population.

Nancy Santesso, Andrew Bryant, Reem A Mustafa, 2017, The Cochrane database of systematic reviews.

GRADE Evidence to Decision (EtD) frameworks for adoption, adaptation, and de novo development of trustworthy recommendations: GRADE-ADOLOPMENT.

Alonso Carrasco-Labra, Romina Brignardello-Petersen, Wojtek Wiercioch, 2017, Journal of clinical epidemiology.

The Diagnostic Accuracy of Syndromic Management for Genital Ulcer Disease: A Systematic Review and Meta-Analysis

R. Ofori-Asenso, N. Santesso, J. Falconer, 2021, Frontiers in Medicine.

Ventilation Techniques and Risk for Transmission of Coronavirus Disease, Including COVID-19

E. Akl, H. Schünemann, J. Brożek, 2020, Annals of Internal Medicine.

Dexamethasone dosing for prevention of acute chemotherapy‐induced vomiting in pediatric patients: A systematic review

N. Santesso, L. Dupuis, P. Robinson, 2020, Pediatric blood & cancer.

A meta-epidemiological study of subgroup analyses in cochrane systematic reviews of atrial fibrillation

Lawrence Mbuagbaw, Nancy Santesso, Robby Nieuwlaat, 2019, Systematic Reviews.

Association Between Inflammatory Bowel Diseases and Celiac Disease: A Systematic Review and Meta-Analysis.

P. Moayyedi, N. Santesso, P. Bercik, 2020, Gastroenterology.

Defining decision thresholds for judgments on health benefits and harms using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision (EtD) frameworks: a protocol for a randomised methodological study (GRADE-THRESHOLD)

L. Mbuagbaw, E. Akl, H. Schünemann, 2022, BMJ Open.

Consideration of antimicrobial resistance and contextual factors in infectious disease guidelines: a systematic survey

L. Moja, M. Loeb, H. Schunemann, 2021, BMJ Open.

Development and use of health outcome descriptors: a guideline development case study

C. de Wolf, H. Schünemann, P. Muti, 2020, Health and Quality of Life Outcomes.

Development of rapid guidelines: 2. A qualitative study with WHO guideline developers

Yuan Zhang, Wojtek Wiercioch, Holger J. Schünemann, 2018, Health Research Policy and Systems.

A methodological survey identified eight proposed frameworks for the adaptation of health related guidelines.

Elie A Akl, Wojtek Wiercioch, Nancy Santesso, 2017, Journal of clinical epidemiology.

Using patient values and preferences to inform the importance of health outcomes in practice guideline development following the GRADE approach

E. Akl, H. Schünemann, J. Brożek, 2017, Health and Quality of Life Outcomes.

A guide for health professionals to interpret and use recommendations in guidelines developed with the GRADE approach.

G. Guyatt, E. Akl, H. Schünemann, 2016, Journal of clinical epidemiology.

World Health Organization Guidelines for treatment of cervical intraepithelial neoplasia 2–3 and screen‐and‐treat strategies to prevent cervical cancer

Nancy Santesso, Marc Arbyn, Lynette Denny, 2016, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

A risk of bias instrument for non-randomized studies of exposures: A users’ guide to its application in the context of GRADE

A. Hansell, E. Akl, H. Schünemann, 2018, Environment international.

Vitamin D Supplementation and Breast Cancer Prevention: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

L. Mariani, A. Giordano, M. Mottolese, 2013, PloS one.

Oral immunotherapy for IgE‐mediated cow's milk allergy: a systematic review and meta‐analysis

H. Schünemann, J. Brożek, L. Terracciano, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Systematic Review of the Incidence of and Risk Factors for Urothelial Cancers and Renal Cell Carcinoma Among Patients with Haematuria.

Yuhong Yuan, B. V. van Rhijn, N. Santesso, 2022, European urology.

Effects of dance on cognitive function among older adults: a protocol for systematic review and meta-analysis

P. Santaguida, D. Merom, L. Thabane, 2018, Systematic Reviews.

A conceptual framework for patient-directed knowledge tools to support patient-centred care: Results from an evidence-informed consensus meeting.

G. Elwyn, J. Grimshaw, S. Flottorp, 2019, Patient education and counseling.

Formatting modifications in GRADE evidence profiles improved guideline panelists comprehension and accessibility to information. A randomized trial.

G. Guyatt, E. Akl, H. Schünemann, 2012, Journal of clinical epidemiology.

Validating the "FACE" instrument using stakeholder perceptions of Feasibility, Acceptability, Cost and Equity in guideline implementation.

Nancy Santesso, Holger J Schünemann, Pablo Alonso-Coello, 2020, Journal of clinical epidemiology.

Facilitators and barriers to clinical practice guideline-consistent supportive care at pediatric oncology institutions: a Children’s Oncology Group study

N. Santesso, L. Dupuis, P. Robinson, 2021, Implementation Science Communications.

GRADE approach to drawing conclusions from a network meta-analysis using a minimally contextualised framework

Gordon H Guyatt, Romina Brignardello-Petersen, Nancy Santesso, 2020, BMJ.

A scoping review and survey provides the rationale, perceptions, and preferences for the integration of randomized and nonrandomized studies in evidence syntheses and GRADE assessments.

G. Guyatt, H. Schünemann, J. Brożek, 2018, Journal of clinical epidemiology.

Recommendations for preventing fracture in long-term care

P. Katz, S. Jaglal, L. Giangregorio, 2015, Canadian Medical Association Journal.

Surgery combined with intraoperative hyperthermic intraperitoneal chemotherapy (IHIC) for gastric cancer: A systematic review and meta-analysis of randomised controlled trials

Ya-li Liu, B. Ma, A. Lethaby, 2013, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus

T. Rader, D. Gladman, M. Urowitz, 2018, The Journal of Rheumatology.

Use of heparins in patients with cancer: individual participant data meta-analysis of randomised trials study protocol

G. Guyatt, W. Ageno, E. Akl, 2016, BMJ Open.

Improving GRADE evidence tables part 1: a randomized trial shows improved understanding of content in summary of findings tables with a new format.

G. Guyatt, P. Tugwell, V. Welch, 2016, Journal of clinical epidemiology.

Teaching critical appraisal skills in healthcare settings.

T. Horsley, R. Stewart, R. Milne, 2011, The Cochrane database of systematic reviews.

Patient and public attitudes to and awareness of clinical practice guidelines: a systematic review with thematic and narrative syntheses

M. Callaghan, I. Kunnamo, K. Ritchie, 2014, BMC Health Services Research.

Non‐randomized studies as a source of complementary, sequential or replacement evidence for randomized controlled trials in systematic reviews on the effects of interventions

P. Tugwell, E. Akl, H. Schünemann, 2013, Research synthesis methods.

Monitoring of Osteonecrosis in Systemic Lupus Erythematosus: A Systematic Review and Metaanalysis

B. Vandermeer, S. Hussein, J. Pope, 2018, The Journal of Rheumatology.

The effectiveness of physiologically based early warning or track and trigger systems after triage in adult patients presenting to emergency departments: a systematic review

P. Meskell, N. Santesso, D. Devane, 2017, BMC Emergency Medicine.

GRADE guidelines: 22. The GRADE approach for tests and strategies-from test accuracy to patient-important outcomes and recommendations.

Mohammad Hassan Murad, Gordon H Guyatt, Lotty Hooft, 2019, Journal of clinical epidemiology.

Decision making about healthcare-related tests and diagnostic test strategies. Paper 3: a systematic review shows limitations in most tools designed to assess quality and develop recommendations.

Wojtek Wiercioch, Jan Brozek, Monika Lelgemann, 2017, Journal of clinical epidemiology.

Teaching critical appraisal skills in healthcare settings (Review)

T. Horsley, R. Stewart, R. Milne, 2011 .

Finding Common Ground in Team-Based Qualitative Research Using the Convergent Interviewing Method

Cindy Gallois, Nancy Santesso, C. Gallois, 2006, Qualitative health research.

A modeling approach to derive baseline risk estimates for GRADE recommendations:Concepts, development, and results of its application to the American Society of Hematology 2019 guidelines on prevention of venous thromboembolism in surgical hospitalized patients.

E. Akl, H. Schünemann, J. Brożek, 2021, Journal of clinical epidemiology.

Improving GRADE evidence tables part 2: a systematic survey of explanatory notes shows more guidance is needed.

H. Schünemann, J. Brożek, T. Lasserson, 2016, Journal of clinical epidemiology.

Development of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Summary of Findings (SoF) Table for Network Meta-analysis.

Yuan Zhang, Lawrence Mbuagbaw, Gordon H. Guyatt, 2019, Journal of clinical epidemiology.

New methods facilitated the process of prioritizing questions and health outcomes in guideline development.

S. Vesely, E. Akl, H. Schünemann, 2021, Journal of clinical epidemiology.

Systematic reviews and knowledge translation.

Nancy Santesso, Jeremy Grimshaw, Peter Tugwell, 2006, Bulletin of the World Health Organization.

GRADE Guidance article 35: Update on rating imprecision for assessing contextualized certainty of evidence and making decisions.

G. Guyatt, E. Akl, M. Vinceti, 2022, Journal of clinical epidemiology.

GRADE notes: Extremely Serious, GRADE's Terminology for Rating Down by 3-Levels.

H. Schünemann, R. Mustafa, J. Meerpohl, 2019, Journal of clinical epidemiology.

Communication Accommodation and Managing Musculoskeletal Disorders: Doctors' and Patients' Perspectives

S. Baker, C. Gallois, S. Driedger, 2011, Health communication.

World Health Organization Guidelines: Use of cryotherapy for cervical intraepithelial neoplasia

Nancy Santesso, Holger Schünemann, Paul Blumenthal, 2012, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Methodological survey of designed uneven randomization trials (DU-RANDOM): a protocol

G. Guyatt, B. Prediger, E. Akl, 2014, Trials.

A taxonomy and framework for identifying and developing actionable statements in guidelines suggests avoiding informal recommendations.

P. Tugwell, L. Mbuagbaw, K. Pottie, 2021, Journal of clinical epidemiology.

Conclusions from surveys may not consider important biases: A systematic survey of surveys.

E. Akl, H. Schünemann, J. Cairney, 2020, Journal of clinical epidemiology.

Hip protectors for preventing hip fractures in older people

N. Santesso, 2014, The Cochrane database of systematic reviews.

Development of a taxonomy of interventions to organise the evidence on consumers' medicines use.

S. Hill, Rebecca Ryan, N. Santesso, 2011, Patient education and counseling.

Development of the effective musculoskeletal consumer scale.

Cindy Gallois, Nancy Santesso, Elizabeth Kristjansson, 2007, The Journal of rheumatology.

Attributes and skills of an effective musculoskeletal consumer.

Cindy Gallois, Nancy Santesso, Janet Wale, 2005, The Journal of rheumatology.

Comparison between the standard and a new alternative format of the Summary-of-Findings tables in Cochrane review users: study protocol for a randomized controlled trial

G. Guyatt, P. Tugwell, V. Welch, 2015, Trials.

Systematic reviews from the Cochrane Musculoskeletal Group.

P. Tugwell, R. Buchbinder, L. Maxwell, 2006, The Journal of the Canadian Chiropractic Association.

Standardized wording to improve efficiency and clarity of GRADE EtD frameworks in health guidelines.

H. Schünemann, N. Santesso, T. Piggott, 2022, Journal of clinical epidemiology.

Reply to higher- versus lower-protein diets

E. Akl, H. Schünemann, D. Heels-Ansdell, 2012, European Journal of Clinical Nutrition.

Decision-Making about Healthcare Related Tests and Diagnostic Strategies: User Testing of GRADE Evidence Tables

Alonso Carrasco-Labra, Amit X. Garg, Romina Brignardello-Petersen, 2014, PLoS ONE.

Presenting Evidence to Patients Online: What Do Web Users Think of Consumer Summaries of Cochrane Musculoskeletal Reviews?

Gitte Lindgaard, Nancy Santesso, Alison Lott, 2011, Journal of medical Internet research.

Long-acting β2-agonist step-off in patients with controlled asthma.

J. Brożek, T. Casale, J. Krishnan, 2012, Archives of internal medicine.

Investigating the role and applicability of patient versions of guidelines in oncology and deriving recommendations for the development, dissemination and implementation of patient versions in Germany: protocol for multiphase study

Monika Becker, D. Pieper, N. Santesso, 2022, BMJ Open.

A 64 year old woman with knee pain: case presentation

P. Tugwell, A. O'Connor, N. Santesso, 2004, BMJ : British Medical Journal.

Responsiveness of the Effective Consumer Scale (EC-17)

P. Tugwell, V. Welch, E. Kristjansson, 2009, The Journal of Rheumatology.

Commentary: Quest for using sound evidence when making decisions about screening.

Nancy Santesso, N. Santesso, 2020, Journal of clinical epidemiology.

The Diagnostic Accuracy of Cystoscopy for Detecting Bladder Cancer in Adults Presenting with Haematuria: A Systematic Review from the European Association of Urology Guidelines Office.

Yuhong Yuan, J. D. de Jong, H. Mostafid, 2023, European Urology Focus.

Outcomes of organ–sparing surgery for adult testicular tumors: A systematic review of the literature

Q. Trinh, K. Zorn, N. Santesso, 2022 .

Consumer‐driven health care: Building partnerships in research

P. Tugwell, G. Wells, V. Robinson, 2005, Health expectations : an international journal of public participation in health care and health policy.

Teaching critical appraisal skills in healthcare settings.

T. Horsley, R. Stewart, R. Milne, 2011, The Cochrane database of systematic reviews.

Evidence that patients can understand and use?

Claire Glenton, Nancy Santesso, C. Glenton, 2008, Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen.

The cost-effectiveness of 10 antenatal syphilis screening and treatment approaches in Peru, Tanzania, and Zambia

R. Peeling, C. Watts, L. Newman, 2015, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

The GRADE approach is reproducible in assessing the quality of evidence of quantitative evidence syntheses.

Stephen J. Gentles, G. Guyatt, E. Akl, 2013, Journal of clinical epidemiology.

Focus groups and interviews with the public led to the development of a template for a GRADE plain language recommendation.

H. Schünemann, N. Santesso, W. Wiercioch, 2021, Journal of clinical epidemiology.

Grading of Recommendations Assessment, Development, and Evaluations (GRADE) notes: extremely serious, GRADE's terminology for rating down by three levels

H. Schünemann, R. Mustafa, J. Meerpohl, 2020, Journal of Clinical Epidemiology.

Procedures and methods of benefit assessments for medicines in Germany: give the child a name

H. Schünemann, R. Kunz, N. Santesso, 2009, The European Journal of Health Economics.

Table of Contents

E. Akl, B. Rochwerg, T. Ortel, 2011, Biological Psychiatry.

World Health Organization Guidelines: Use of cryotherapy for cervical intraepithelial neoplasia

H. Schünemann, N. Santesso, P. Blumenthal, 2012, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

Antivirals for Treatment of Influenza

E. Akl, S. Flottorp, H. Schünemann, 2012, Annals of Internal Medicine.

Standardized wording to improve efficiency and clarity of GRADE EtD frameworks in health guidelines.

H. Schünemann, N. Santesso, Tejan Baldeh, 2022, Journal of clinical epidemiology.