D. Smeets

发表

Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations

Lajos Pusztai, Diether Lambrechts, Christine Desmedt, 2017, Nature Communications.

Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing

P. D. Rijk, P. Loo, D. Lambrechts, 2011, Nature Biotechnology.

PALB2,CHEK2 and ATM rare variants and cancer risk: Data from COGS

Dong Liang, Jane E. Carpenter, Peter Kraft, 2016 .

Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach

M. Ebert, D. Lambrechts, B. Ylstra, 2017, Oncotarget.

Genetic variability in drug transport, metabolism or DNA repair affecting toxicity of chemotherapy in ovarian cancer

P. Neven, D. Lambrechts, F. Amant, 2015, BMC Pharmacology and Toxicology.

Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis

C. Sotiriou, D. Lambrechts, D. Peeters, 2022, npj Breast Cancer.

Copy number alterations as predictive biomarkers for response to bevacizumab in metastatic colorectal cancer

M. Ebert, D. Lambrechts, B. Ylstra, 2016 .

The rs1800716 variant in CYP2D6 is associated with an increased double endometrial thickness in postmenopausal women on tamoxifen.

D. Timmerman, P. Neven, D. Lambrechts, 2014, Annals of oncology : official journal of the European Society for Medical Oncology.

Evidence of Gene–Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors

Patrick Neven, Daniel F. Schmidt, Julian Peto, 2013, PLoS genetics.

Ischemia-Induced DNA Hypermethylation during Kidney Transplant Predicts Chronic Allograft Injury.

D. Lambrechts, B. Thienpont, E. Lerut, 2018, Journal of the American Society of Nephrology : JASN.

A Complex Network of Tumor Microenvironment in Human High-Grade Serous Ovarian Cancer

Bram Boeckx, Georg Heinze, Ignace Vergote, 2017, Clinical Cancer Research.

Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks

Alexander M. Metcalf, A. Spurdle, S. Aerts, 2014, eLife.

Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching

D. Lambrechts, J. Wouters, S. Tejpar, 2016, British Journal of Cancer.

Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer.

S Michiels, C Sotiriou, C. Sotiriou, 2014, Annals of oncology : official journal of the European Society for Medical Oncology.

Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer

M. Ebert, D. Lambrechts, B. Ylstra, 2020, Scientific Reports.

The genomic landscape of nonsmall cell lung carcinoma in never smokers

D. Lambrechts, G. Berchem, B. Boeckx, 2019, International journal of cancer.

Chromosomal Instability in Cell-Free DNA as a Highly Specific Biomarker for Detection of Ovarian Cancer in Women with Adnexal Masses

D. Timmerman, P. Neven, D. Lambrechts, 2016, Clinical Cancer Research.

The TERT-CLPTM1L locus for lung cancer predisposes to bronchial obstruction and emphysema

J Verschakelen, M. Decramer, D. Lambrechts, 2011, European Respiratory Journal.

Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer.

E. Berns, D. Lambrechts, R. Zeillinger, 2016, European journal of cancer.

Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer.

E. Berns, D. Lambrechts, C. Singer, 2019, Cancer letters.

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

M. Ebert, D. Lambrechts, B. Ylstra, 2018, Nature Communications.

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

Sandra L. Halverson, A. Whittemore, L. Kiemeney, 2016, Gynecologic oncology.

Genetic variation at CYP 3 A is associated with age at menarche and breast cancer risk : a case-control study

Jaana M. Hartikainen, S. Cross, M. Beckmann, 2014 .

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

Patrick Neven, Chiun-Sheng Huang, Julian Peto, 2014, Breast Cancer Research.

DNA methylation profiling of non-small cell lung cancer reveals a COPD-driven immune-related signature

M. Decramer, D. Lambrechts, W. Janssens, 2015, Thorax.

Molecular characterization of 7 new established cell lines from high grade serous ovarian cancer.

G. Heinze, D. Lambrechts, R. Zeillinger, 2015, Cancer letters.

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

M. Ebert, D. Lambrechts, B. Ylstra, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma

D. Lambrechts, R. Sciot, M. Debiec‐Rychter, 2015, Oncotarget.

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

Jaana M. Hartikainen, Kristen S Purrington, Ali Amin Al Olama, 2014, Human molecular genetics.

Mixed adenoneuroendocrine carcinoma of the colon: molecular pathogenesis and treatment.

D. Lambrechts, D. Smeets, A. Hoorens, 2014, Anticancer research.

Identification, clinical-pathological characteristics and treatment outcomes of patients with metastatic breast cancer and somatic human epidermal growth factor receptor 2 (ERBB2) mutations

P. Neven, D. Lambrechts, H. Wildiers, 2018, Breast Cancer Research and Treatment.

PALB2,CHEK2 and ATM rare variants and cancer risk: Data from COGS

Jane E. Carpenter, Lara E Sucheston-Campbell, Ali Amin Al Olama, 2016 .

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

Jane E. Carpenter, Lara E Sucheston-Campbell, A. Whittemore, 2016, Journal of Medical Genetics.