X. Cen

发表

Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease

Hualiang Jiang, Yechun Xu, Jian Li, 2020, Science.

Taurine protects methamphetamine-induced developmental angiogenesis defect through antioxidant mechanism.

X. Cen, Yinglan Zhao, Yi Deng, 2012, Toxicology and applied pharmacology.

Synapse differentiation-induced gene 1 regulates stress-induced depression through interaction with the AMPA receptor GluA2 subunit of nucleus accumbens in male mice

X. Cen, Yuman He, Q. Bu, 2022, Neuropharmacology.

NMR-based metabonomic in hippocampus, nucleus accumbens and prefrontal cortex of methamphetamine-sensitized rats.

Yanli Wang, X. Cen, Pengchi Deng, 2013, Neurotoxicology.

Mechanism study of Aconitum-induced neurotoxicity in PC12 cells: involvement of dopamine release and oxidative damage.

X. Cen, Yan Zhou, Yinglan Zhao, 2010, Neurotoxicology.

1H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention

X. Cen, Yinglan Zhao, Yi Deng, 2012, Behavioural Brain Research.

1H‐nuclear magnetic resonance‐based metabonomic analysis of brain in rhesus monkeys with morphine treatment and withdrawal intervention

X. Cen, Yinglan Zhao, Pengchi Deng, 2012, Journal of neuroscience research.

Three-month subchronic intramuscular toxicity study of rotigotine-loaded microspheres in Cynomolgus monkeys.

P. Yu, G. Du, L. Ye, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Lipidomics Reveals Dysregulated Glycerophospholipid Metabolism in the Corpus Striatum of Mice Treated with Cefepime.

Jingwei Tian, X. Cen, Yuman He, 2021, ACS chemical neuroscience.

Evaluation of gamma ray-induced gastrointestinal tract morphological and proliferative activity changes in rhesus monkeys

X. Cen, H. Li, T. Chen, 2016, Human & experimental toxicology.

Toxicity effects of a novel potent triple reuptake inhibitor, LPM570065, on the fertility and early embryonic development in Sprague‐Dawley rats

Haibo Zhu, L. Ye, Jingwei Tian, 2018, Regulatory toxicology and pharmacology : RTP.

Ghrelin inhibits doxorubicin cardiotoxicity by inhibiting excessive autophagy through AMPK and p38-MAPK.

X. Cen, Dan Wu, Wei Jiang, 2014, Biochemical pharmacology.

Nicotinamide phosphoribosyltransferase regulates cocaine reward through Sirtuin 1

X. Cen, Yinglan Zhao, X. Shao, 2018, Experimental Neurology.

Uric Acid Induces Cognitive Dysfunction through Hippocampal Inflammation in Rodents and Humans

Fabao Gao, X. Cen, Wenjie Lu, 2016, The Journal of Neuroscience.

Synthesis, biological, and structural explorations of a series of μ-opioid receptor (MOR) agonists with high G protein signaling bias.

Wenyan Wang, Jingwei Tian, Chunmei Li, 2021, European journal of medicinal chemistry.

Lipidomics Reveals Glycerophospholipid Metabolism Dysregulation in the Corpus Striatum of Mice Treated with Cefepime

Jingwei Tian, X. Cen, Yuman He, 2021 .

Brain Renin–Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity

Jingwei Tian, Wei Guo, X. Cen, 2018, Neurotherapeutics.

Combined transcriptomic and lipidomic analysis reveals aberrant lipid metabolism in central nervous system hemangioblastomas

X. Cen, Qiguang Wang, Wen-ke Liu, 2021, Scientific Reports.

MicroRNAs in drug addiction: Current status and future perspectives.

Jingwei Tian, X. Cen, Hongbo Wang, 2022, Pharmacology & therapeutics.

Integrated lipidomic and transcriptomic analysis reveals clarithromycin-induced alteration of glycerophospholipid metabolism in the cerebral cortex of mice

Jingwei Tian, X. Cen, Yinglan Zhao, 2021, Cell Biology and Toxicology.

The Safety of Propofol Versus Sevoflurane for General Anesthesia in Children: A Meta-Analysis of Randomized Controlled Trials

Yuhang Liu, X. Cen, Feng Qin, 2022, Frontiers in Surgery.

Mechanisms of Metabonomic for a Gateway Drug: Nicotine Priming Enhances Behavioral Response to Cocaine with Modification in Energy Metabolism and Neurotransmitter Level

X. Cen, Yinglan Zhao, Yi Deng, 2014, PloS one.

Six months chronic toxicological evaluation of naringin in Sprague-Dawley rats.

W. Su, X. Cen, Chunyan Hu, 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Involvement of the Drug Transporters P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2 in Telithromycin Transport

K. Takagi, X. Cen, M. Nadai, 2006, Antimicrobial Agents and Chemotherapy.

Shiga-like toxin II modifies brain distribution of a P-glycoprotein substrate, doxorubicin, and P-glycoprotein expression in mice

T. Hasegawa, K. Takagi, K. Kitaichi, 2002, Brain Research.

Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta-catenin

X. Cen, Yongjie Wu, Baolai Zhang, 2015, Journal of Translational Medicine.

Accuracy improvement of electrochemical whole blood ketone sensor based on HCT compensation algorithm

X. Cen, Hui Gu, Hongchun Li, 2020, Electrophoresis.

ZY0511, a novel, potent and selective LSD1 inhibitor, exhibits anticancer activity against solid tumors via the DDIT4/mTOR pathway.

Sheng-yong Yang, Hu Zhang, X. Cen, 2019, Cancer letters.

Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization

T. Nabeshima, A. Nitta, X. Cen, 2008, Molecular Psychiatry.

4R Tau Modulates Cocaine-Associated Memory through Adult Dorsal Hippocampal Neurogenesis

J Zhang, Jingwei Tian, X. Cen, 2021, The Journal of Neuroscience.

4R Tau Modulates Cocaine-Associated Memory Through Adult Hippocampal Neurogenesis

J Zhang, Jingwei Tian, X. Cen, 2020 .

Mitochondrial protein dysfunction in pathogenesis of neurological diseases

X. Cen, Shiming Pu, Hongxia Zhao, 2022, Frontiers in Molecular Neuroscience.

Shiga-Like Toxin II Derived from Escherichia coli O157:H7 Modifies Renal Handling of Levofloxacin in Rats

T. Hasegawa, K. Yokoyama, K. Takagi, 2002, Antimicrobial Agents and Chemotherapy.

Protective Role of Taurine Against Morphine-Induced Neurotoxicity in C6 Cells via Inhibition of Oxidative Stress

X. Cen, Yinglan Zhao, Yi Deng, 2011, Neurotoxicity Research.

mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1–GluA2 interaction in the nucleus accumbens

J Zhang, X. Cen, Zhen Yang, 2021, Acta Pharmacologica Sinica.

Rational Design of Quinoxalinone-Based Red-Emitting Probes for High-Affinity and Long-Term Visualizing Amyloid-β In Vivo.

Yan-hong Liu, Kun Li, X. Cen, 2022, Analytical chemistry.

Arginine Methyltransferase 1 in the Nucleus Accumbens Regulates Behavioral Effects of Cocaine.

L. Zhong, Sheng-yong Yang, X. Cen, 2015, The Journal of neuroscience : the official journal of the Society for Neuroscience.

A self-assembled trimeric protein vaccine induces protective immunity against Omicron variant

Xiaozhong Peng, Xiaohua Jiang, Xiangrong Song, 2022, Nature Communications.

Acute toxicity and genotoxicity studies on poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanomaterials.

Z. Qian, M. Gou, X. Cen, 2010, Mutation research.

Acrylamide exposure represses neuronal differentiation, induces cell apoptosis and promotes tau hyperphosphorylation in hESC-derived 3D cerebral organoids.

Ke Chen, X. Cen, Yan Huang, 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Publisher Correction: A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

Yuquan Wei, Sheng Lin, M. Shi, 2021, Nature.

Prevalence and associated factors of cognitive impairment among the elderly population: A nationwide cross-sectional study in China

W. Kuang, X. Cen, Yang Xiong, 2022, Frontiers in Public Health.

Remodeling the homeostasis of pro- and anti-angiogenic factors by Shenmai injection to normalize tumor vasculature for enhanced cancer chemotherapy.

Guangji Wang, X. Cen, P. Ni, 2020, Journal of ethnopharmacology.

β-hydroxybutyrate reduces reinstatement of cocaine conditioned place preference through hippocampal CaMKII-α β-hydroxybutyrylation.

Liang Wang, J Zhang, Jingwei Tian, 2022, Cell reports.

b -hydroxybutyrate reduces reinstatement of cocaine conditioned place preference through hippocampal CaMKII- a b -hydroxybutyrylation

Liang Wang, J Zhang, Jingwei Tian, 2022 .

Investigation of toxicological effects of Shuanghuanglian injection in Beagle dogs by metabonomic and traditional approaches

Yanli Wang, X. Cen, Yinglan Zhao, 2010, Experimental biology and medicine.

1H-NMR based metabonomic profiling of human esophageal cancer tissue

X. Cen, Wenjie Lu, Pengchi Deng, 2013, Molecular Cancer.

Structure-Based Design, Synthesis and Biological Evaluation of Peptidomimetic Aldehydes as a Novel Series of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease

Hualiang Jiang, Yechun Xu, Jian Li, 2020, bioRxiv.

NMR-based metabonomic study of the sub-acute toxicity of titanium dioxide nanoparticles in rats after oral administration

Qian Bu, Guangyan Yan, Yanli Wang, 2010, Nanotechnology.

A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

Yuquan Wei, Sheng Lin, M. Shi, 2020, Nature.

A 12-week subchronic intramuscular toxicity study of risperidone-loaded microspheres in rats

G. Du, X. Cen, J. Tian, 2015, Human & experimental toxicology.

Lipidomic profiling reveals lipid regulation by a novel LSD1 inhibitor treatment

Sheng-yong Yang, X. Cen, Lei Tao, 2021, Oncology reports.

Reprogramming of lipid metabolism in cancer-associated fibroblasts potentiates migration of colorectal cancer cells

Na Sang, X. Cen, Yinglan Zhao, 2020, Cell Death & Disease.

HMG-CoA synthase 2 drives brain metabolic reprogramming in cocaine exposure

Jie Zhang, X. Cen, Yinglan Zhao, 2017, Neuropharmacology.

Transcriptome analysis of long non‐coding RNAs of the nucleus accumbens in cocaine‐conditioned mice

Yan Li, Xue Shao, Qian Bu, 2012, Journal of neurochemistry.

1H NMR-based metabonomics in brain nucleus accumbens and striatum following repeated cocaine treatment in rats

X. Cen, Q. Bu, X. Shao, 2012, Neuroscience.

Targeting protein arginine methyltransferase 5 inhibits colorectal cancer growth by decreasing arginine methylation of eIF4E and FGFR3

X. Cen, Yongjie Wu, Yinglan Zhao, 2015, Oncotarget.

Cocaine induces differential circular RNA expression in striatum

B. Liu, Jingwei Tian, X. Cen, 2019, Translational Psychiatry.

Cytoplasmic SHMT2 drives the progression and metastasis of colorectal cancer by inhibiting β-catenin degradation

Zongguang Zhou, Yong Peng, Hu Zhang, 2021, Theranostics.

Endocannabinoid signaling regulates the reinforcing and psychostimulant effects of ketamine in mice

Jingwei Tian, X. Cen, Yinglan Zhao, 2020, Nature Communications.

Chronic Alcohol Causes Alteration of Lipidome Profiling in Brain.

X. Cen, Yinglan Zhao, Q. Bu, 2019, Toxicology letters.

Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation

X. Cen, Yinglan Zhao, Q. Bu, 2015, Neurobiology of Disease.

Taurine attenuates methamphetamine-induced autophagy and apoptosis in PC12 cells through mTOR signaling pathway.

X. Cen, Wenjie Lu, Yinglan Zhao, 2012, Toxicology letters.

NMR-Based Metabolic Profiling Reveals Neurochemical Alterations in the Brain of Rats Treated with Sorafenib

X. Cen, Yinglan Zhao, Pengchi Deng, 2015, Neurotoxicity Research.

A novel molecule ‘shati’ increases dopamine uptake via the induction of tumor necrosis factor‐α in pheochromocytoma‐12 cells

T. Nabeshima, A. Nitta, N. Ozaki, 2008, Journal of neurochemistry.

Recent advances of mitochondrial complex I inhibitors for cancer therapy: Current status and future perspectives.

X. Cen, Yinglan Zhao, Yangli Zhou, 2023, European journal of medicinal chemistry.

Cocaine modifies brain lipidome in mice

X. Cen, Yinglan Zhao, Wei Xu, 2017, Molecular and Cellular Neuroscience.

Brain Renin–Angiotensin System Blockade Attenuates Methamphetamine-Induced Hyperlocomotion and Neurotoxicity

Jingwei Tian, Wei Guo, X. Cen, 2018, Neurotherapeutics.

Neonatal exposure to sevoflurane induces adolescent neurobehavioral dysfunction by interfering with hippocampal glycerophoslipid metabolism in rats.

Jingwei Tian, X. Cen, Yuman He, 2022, Cerebral cortex.

Role of BRD4 phosphorylation in the nucleus accumbens in relapse to cocaine-seeking behavior in mice.

Jingwei Tian, W. Guo, X. Cen, 2020, Addiction biology.

Untargeted lipidomic analysis of human hippocampus for temporal lobe epilepsy with hippocampal sclerosis

X. Cen, Heng Zhang, Hong Gao, 2020, Epilepsy Research.

1H-Nuclear magnetic resonance-based metabolomic analysis of brain in mice with nicotine treatment

X. Cen, Yinglan Zhao, Q. Bu, 2014, BMC Neuroscience.

An Analog of a Dipeptide-Like Structure of FK506 Increases Glial Cell Line-Derived Neurotrophic Factor Expression through cAMP Response Element-Binding Protein Activated by Heat Shock Protein 90/Akt Signaling Pathway

T. Nabeshima, Kuniaki Saito, A. Nitta, 2006, The Journal of Neuroscience.

Proteomic analysis of the nucleus accumbens in rhesus monkeys of morphine dependence and withdrawal intervention.

X. Cen, Yinglan Zhao, Chunyan Hu, 2012, Journal of proteomics.

Multimodal imaging and electroretinography highlights the role of VEGF in the laser-induced subretinal fibrosis of monkey.

X. Cen, Danian Chen, Yuliang Feng, 2020, Experimental eye research.

Lipidomic signature of serum from the rats exposed to alcohol for one year.

Jingwei Tian, W. Guo, X. Cen, 2018, Toxicology letters.

Zinc oxide nanoparticles cause nephrotoxicity and kidney metabolism alterations in rats

Yanli Wang, Qiangqiang Liu, X. Cen, 2012, Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.

Synergistic antitumor effect of 5-fluorouracil with the novel LSD1 inhibitor ZY0511 in colorectal cancer

Sheng-yong Yang, X. Cen, Yinglan Zhao, 2020, Therapeutic advances in medical oncology.

Cardiolipin and OPA1 Team up for Methamphetamine-Induced Locomotor Activity by Promoting Neuronal Mitochondrial Fusion in the Nucleus Accumbens of Mice.

Liang Wang, X. Cen, Q. Bu, 2023, ACS chemical neuroscience.

Adverse events of tumor necrosis factor alpha inhibitors for the treatment of ankylosing spondylitis: A meta-analysis of randomized, placebo-controlled trials

X. Cen, Weihong Kuang, Feng Qin, 2023, Frontiers in Pharmacology.

Remodeling of brain lipidome in methamphetamine-sensitized mice.

X. Cen, Yinglan Zhao, Ruiming Zhu, 2017, Toxicology letters.

Simvastatin Blocks Reinstatement of Cocaine-induced Conditioned Place Preference in Male Mice with Brain Lipidome Remodeling

X. Cen, Yuman He, Linhong Jiang, 2021, Neuroscience Bulletin.

Toll-like receptor 3 modulates the behavioral effects of cocaine in mice

Jingwei Tian, Wei Guo, X. Cen, 2018, Journal of neuroinflammation.

Uric Acid Produces an Inflammatory Response through Activation of NF-κB in the Hypothalamus: Implications for the Pathogenesis of Metabolic Disorders

X. Cen, Yinglan Zhao, Liangxue Zhou, 2015, Scientific Reports.

A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

Wei Cheng, Sheng Lin, M. Shi, 2020, Nature.

Morphine Re-arranges Chromatin Spatial Architecture of Primate Cortical Neurons

Liang Wang, Jingwei Tian, W. Kuang, 2023, bioRxiv.

Three-month subchronic intramuscular toxicity study of rotigotine-loaded microspheres in SD rats.

P. Yu, G. Du, L. Ye, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Reproductive and developmental toxicity assessments of LPM3480392, a novel mu opioid receptor biased agonist in rats.

Jingwei Tian, Bin Liu, Chunmei Li, 2023, Reproductive toxicology.

Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta-catenin

X. Cen, Yongjie Wu, Baolai Zhang, 2015, Journal of Translational Medicine.

Ampelopsin sodium exhibits antitumor effects against bladder carcinoma in orthotopic xenograft models

Hongxia Zhang, X. Cen, Yongjie Wu, 2012, Anti-cancer drugs.

Corrigendum to "ZY0511, a novel, potent and selective LSD1 inhibitor, exhibits anticancer activity against solid tumors via the DDIT4/mTOR pathway" [Cancer Lett. 454 (2019) 179-190].

Sheng-yong Yang, X. Cen, Lei Tao, 2019, Cancer letters.

Reprogramming of lipid metabolism in cancer-associated fibroblasts potentiates migration of colorectal cancer cells

Na Sang, X. Cen, Yinglan Zhao, 2020, Cell Death & Disease.

Generation of an NANS homozygous knockout human induced pluripotent stem cell line by the insertion of GFP-P2A-Puro via CRISPR/Cas9 editing.

X. Cen, Hong Gao, Kai Zhong, 2020, Stem cell research.