J. Cohn

发表

Cystic fibrosis gene mutations and pancreatitis risk: relation to epithelial ion transport and trypsin inhibitor gene mutations.

M. Knowles, L. Silverman, P. Noone, 2001, Gastroenterology.

Increased risk of idiopathic chronic pancreatitis in cystic fibrosis carriers

W. Greenhalf, J. Neoptolemos, S. Sommer, 2005, Human mutation.

Submucosal glands are the predominant site of CFTR expression in the human bronchus

James M. Wilson, Yiping Yang, J. Yankaskas, 1992, Nature Genetics.

Molecular basis of defective anion transport in L cells expressing recombinant forms of CFTR.

F. Collins, J. Wilson, J. Engelhardt, 1993, Human molecular genetics.

Motion--genetic testing is useful in the diagnosis of nonhereditary pancreatic conditions: arguments against the motion.

J. Cohn, 2003, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment.

J. Wilson, J. Cohn, J. M. Wilson, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Stimulation of secretion by the T84 colonic epithelial cell line with dietary flavonols.

T. Gettys, J. Cohn, T. Nguyen, 1991, Biochemical pharmacology.

Multiple calcium-mediated effector mechanisms regulate chloride secretory responses in T84-cells.

J. Cohn, K. Dharmsathaphorn, G. Beuerlein, 1989, The American journal of physiology.

Chemical characterization of a protein-4-hydroxy-2-nonenal cross-link: immunochemical detection in mitochondria exposed to oxidative stress.

B. Friguet, J. Cohn, L. Szweda, 1996, Archives of biochemistry and biophysics.

Pituitary adenylate cyclase-activating polypeptide stimulates secretion in T84 cells.

J. Cohn, T. Nguyen, G. Heintz, 1992, Gastroenterology.

Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injury.

J. Cohn, L. Mandel, J. Chen, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Protein kinase A regulates ATP hydrolysis and dimerization by a CFTR (cystic fibrosis transmembrane conductance regulator) domain.

L. D. Howell, J. Cohn, R. Borchardt, 2004, The Biochemical journal.

Cl- and K+ transport in human biliary cell lines.

J. Cohn, A. Mangel, J. Middleton, 1993, Gastroenterology.

Missense mutation (G480C) in the CFTR gene associated with protein mislocalization but normal chloride channel activity.

M. Macek, G. Cutting, D. Wood, 1995, Human molecular genetics.

An approach for treating the hepatobiliary disease of cystic fibrosis by somatic gene transfer.

J. Wilson, S. Raper, J. Engelhardt, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles.

R. Bridges, J. Cohn, C. Venglarik, 1994, The Journal of biological chemistry.

Protein phosphorylation responses in normal and cystic fibrosis airway epithelial cell lines.

J. Yankaskas, J. Cohn, J. Kole, 1993, American journal of respiratory cell and molecular biology.

Calmodulin-stimulated protein kinase activity from rat pancreas

J. Gershoni, S. Freedman, J. Cohn, 1983, The Journal of cell biology.

Purification and properties of a multifunctional calcium/calmodulin-dependent protein kinase from rat pancreas.

J. Cohn, F. Gorelick, B. Kinder, 1987, Biochimica et biophysica acta.

Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis.

M. Knowles, L. Silverman, P. Noone, 1998, The New England journal of medicine.

Localization of the cystic fibrosis transmembrane conductance regulator in pancreas.

J. Cohn, C. Marino, F. Gorelick, 1991, The Journal of clinical investigation.

Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation.

L. D. Howell, R. Dérand, J. Cohn, 2001, American journal of physiology. Cell physiology.

ATP hydrolysis by a CFTR domain: pharmacology and effects of G551D mutation.

L. D. Howell, J. Cohn, R. Borchardt, 2000, Biochemical and biophysical research communications.

Protein kinase C mediates cholinergically regulated protein phosphorylation in a Cl(-)-secreting epithelium.

J. Cohn, 1990, The American journal of physiology.

Histamine stimulates calcium-mediated protein phosphorylation in a colonic epithelial cell line.

J. Cohn, W. King, N. Dougherty, 1989, Biochemical and biophysical research communications.

Cystic fibrosis mutations and genetic predisposition to idiopathic chronic pancreatitis.

P. Jowell, J. Cohn, J. Bornstein, 2000, The Medical clinics of North America.

Cystic Fibrosis Transmembrane Regulator Regulates Uptake of Sphingoid Base Phosphates and Lysophosphatidic Acid

Y. Hannun, L. Obeid, B. Ogretmen, 2001, The Journal of Biological Chemistry.

Expression of the cystic fibrosis gene in adult human lung.

James M. Wilson, J. Wilson, J. Yankaskas, 1994, The Journal of clinical investigation.

Expression of an abundant alternatively spliced form of the cystic fibrosis transmembrane conductance regulator (CFTR) gene is not associated with a cAMP-activated chloride conductance.

J. Wilson, R. Frizzell, D. Devor, 1993, Human molecular genetics.

Salt stress increases abundance and glycosylation of CFTR localized at apical surfaces of salt gland secretory cells.

J. Cohn, S. A. Ernst, M. Post, 1994, The American journal of physiology.

Regulation of membrane chloride currents in rat bile duct epithelial cells.

J. Cohn, J. Fitz, S. Basavappa, 1993, The Journal of clinical investigation.

K. Barrett, J. Cohn, S. Wasserman, 1990, The American journal of physiology.

Are mutations in the cystic fibrosis gene important in chronic pancreatitis?

P. Jowell, J. Cohn, 1999, The Surgical clinics of North America.

Cystic fibrosis in the pancreas: Recent advances provide new insights

J. Cohn, J. Bornstein, 1999, Current gastroenterology reports.

Is Idiopathic Chronic Pancreatitis Cystic Fibrosis

J. Cohn, 1999 .

Abnormalities of the CFTR gene predispose to idiopathic chronic pancreatitis

C. Q. Lee, M. Knowles, L. Silverman, 1998 .

Correction of Aberrant Splicing of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene by Antisense Oligonucleotides*

M. Knowles, R. Kole, L. Silverman, 1999, The Journal of Biological Chemistry.

5' exon replacement and repair by spliceosome-mediated RNA trans-splicing.

M. Garcia-Blanco, L. Mitchell, S. Mansfield, 2003, RNA.

Giant two‐dimensional gel electrophoresis: Methodological update and comparison with intermediate‐format gel systems

P. Blackshear, J. Cohn, G. Anderson, 1990, Electrophoresis.

Localization of the cystic fibrosis transmembrane conductance regulator in human bile duct epithelial cells.

F. Collins, A. Nairn, M. Picciotto, 1993, Gastroenterology.

Vasoactive intestinal peptide stimulates protein phosphorylation in a colonic epithelial cell line.

J. Cohn, 1987, The American journal of physiology.

Structural cues involved in endoplasmic reticulum degradation of G85E and G91R mutant cystic fibrosis transmembrane conductance regulator.

J. Widdicombe, J. Cohn, W. Skach, 1997, The Journal of clinical investigation.

Partial correction of endogenous ΔF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing

M. Garcia-Blanco, L. Mitchell, J. Engelhardt, 2002, Nature Biotechnology.

Repair of CFTR mRNA by spliceosome-mediated RNA trans-splicing

M. Garcia-Blanco, L. Mitchell, S. Mansfield, 2000, Gene Therapy.

Gene targeting of a CFTR allele in HT29 human epithelial cells

J. Gearhart, C. Montrose‐Rafizadeh, M. Montrose, 1997, Journal of cellular physiology.

Phosphorylation of the cystic fibrosis transmembrane conductance regulator.

P. Greengard, A. Nairn, M. Picciotto, 1992, The Journal of biological chemistry.

Human cystic fibrosis transmembrane conductance regulator directed to respiratory epithelial cells of transgenic mice

B. Stripp, J. Whitsett, James M. Wilson, 1992, Nature genetics.

Characterization of the cystic fibrosis transmembrane conductance regulator in a colonocyte cell line.

A. Nairn, J. Cohn, C. Marino, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Reduced CFTR function and the pathobiology of idiopathic pancreatitis.

J. Cohn, 2005, Journal of clinical gastroenterology.

The impact of cystic fibrosis and PSTI/SPINK1 gene mutations on susceptibility to chronic pancreatitis.

P. Jowell, J. Cohn, R. Mitchell, 2005, Clinics in laboratory medicine.

The role of cystic fibrosis gene mutations in determining susceptibility to chronic pancreatitis.

P. Jowell, J. Cohn, R. Mitchell, 2004, Gastroenterology clinics of North America.

Idiopathic Pancreatitis Related to CFTR: Complex Inheritance and Identification of a Modifier Gene

P. Noone, P. Jowell, J. Cohn, 2002, Journal of Investigative Medicine.

Protein kinase C and Ca2+ activation of mucin secretion in airway goblet cells.

J. Cohn, L. Abdullah, C. W. Davis, 1997, The American journal of physiology.

CFTR: development of high- affinity antibodies and localization in sweat gland.

J. Cohn, L. Page, S. Vigna, 1991, Biochemical and biophysical research communications.

Evaluation of the policy of empiric treatment of suspected Toxoplasma encephalitis in patients with the acquired immunodeficiency syndrome.

R. Holzman, J. Cohn, J. Jacobs, 1989, The American journal of medicine.

Phosphatidic acid modulates Cl- secretion in T84 cells: varying effects depending on mode of stimulation.

K. Barrett, J. Cohn, U. Kachintorn, 1993, The American journal of physiology.

Pancreatic Exocrine Dysfunction

D. Whitcomb, J. Cohn, 1998 .

Molecular pathogenesis of chronic pancreatitis associated with abnormal CFTR genotypes

M. Knowles, L. Silverman, P. Noone, 2000 .

The ligand binding domain of the epidermal growth factor receptor is not required for receptor dimerization.

J. Cohn, M. Kwatra, D. D. Bigner, 1992, Biochimica et biophysica acta.

Calmodulin-stimulated protein kinase activity from rat pancreas

J. Gershoni, S. Freedman, J. Cohn, 1983, The Journal of cell biology.