E. Koo

T. Arumugam, D. Jo, Christopher P. Chen, 2022, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The melanocytotoxicity of gamma-L-glutaminyl-4-hydroxybenzene: a study of the pigmented cells in the mouse eye.

P. Burger, F. Vogel, E. Koo, 1981, The American journal of pathology.

Inhibitors of Rho-kinase modulate amyloid-beta (Abeta) secretion but lack selectivity for Abeta42.

S. Weggen, T. Golde, E. Koo, 2006, Journal of neurochemistry.

Phorbol esters affect multiple steps in beta-amyloid precursor protein trafficking and amyloid beta-protein production.

E. Koo, 1997, Molecular medicine.

Presymptomatic Increase of an Extracellular RNA in Blood Plasma Associates with the Development of Alzheimer’s Disease

Sheng Zhong, E. Koo, Zixu Zhou, 2020, Current Biology.

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

D. G. Clark, C. Carlson, K. Lunetta, 2014, JAMA neurology.

Amyloid Precursor Protein Trafficking, Processing, and Function*

E. Koo, Edward H Koo, Gopal Thinakaran, 2008, Journal of Biological Chemistry.

Aβ42-lowering Nonsteroidal Anti-inflammatory Drugs Preserve Intramembrane Cleavage of the Amyloid Precursor Protein (APP) and ErbB-4 Receptor and Signaling through the APP Intracellular Domain*

S. Weggen, T. Golde, E. Koo, 2003, Journal of Biological Chemistry.

Amyloid precursor protein (APP) regulates synaptic structure and function

P. Hof, D. Dickstein, E. Koo, 2012, Molecular and Cellular Neuroscience.

Rapid, concurrent alterations in pre- and postsynaptic structure induced by naturally-secreted amyloid-β protein

S. Halpain, E. Koo, B. Calabrese, 2007, Molecular and Cellular Neuroscience.

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Rong Wang, Pritam Das, Jason L. Eriksen, 2001, Nature.

Regulation and genetic control of brain amyloid

S. Prusiner, D. Price, C. Masters, 1991, Brain Research Reviews.

Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice

T. Golde, M. Murphy, E. Koo, 2007, BMC Neuroscience.

Machine learning classifies predictive kinematic features in a mouse model of neurodegeneration

Daniel C. Lu, A. A. Nikooyan, J. Leiter, 2021, Scientific Reports.

Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine Tissues

D. Price, L. Martin, S. Gandy, 1996, The Journal of Neuroscience.

Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function

P. Hof, D. Dickstein, Brea Midthune, 2012, Molecular and Cellular Neuroscience.

The aspartate-257 of presenilin 1 is indispensable for mouse development and production of β-amyloid peptides through β-catenin-independent mechanisms

Hui Zheng, A. Takashima, H. Yamaguchi, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Loss of presenilin 1 is associated with enhanced β-catenin signaling and skin tumorigenesis

Hui Zheng, E. Koo, S. Soriano, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Presenilin 1 Negatively Regulates β-Catenin/T Cell Factor/Lymphoid Enhancer Factor-1 Signaling Independently of β-Amyloid Precursor Protein and Notch Processing

Hui Zheng, D. Kang, R. Pestell, 2001, The Journal of cell biology.

E. Masliah, D. Kang, E. Koo, 2000, Microscopy research and technique.

The Alzheimer-related gene presenilin 1 facilitates notch 1 in primary mammalian neurons.

B T Hyman, S. Tonegawa, B. Hyman, 1999, Brain research. Molecular brain research.

Presenilin 1 Facilitates the Constitutive Turnover of β-Catenin: Differential Activity of Alzheimer’s Disease–Linked PS1 Mutants in the β-Catenin–Signaling Pathway

M. Frosch, T. Collins, D. Kang, 1999, The Journal of Neuroscience.

Perturbed neurogenesis in the adult hippocampus associated with presenilin-1 A246E mutation.

E. Masliah, D. Kang, E. Koo, 2005, The American journal of pathology.

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

R. Sherrington, D. Selkoe, P. Fraser, 1997, Neurobiology of Disease.

Enhanced Production and Oligomerization of the 42-residue Amyloid β-Protein by Chinese Hamster Ovary Cells Stably Expressing Mutant Presenilins*

D. Selkoe, D. Teplow, D. Kholodenko, 1997, The Journal of Biological Chemistry.

Isolation and characterization of Drosophila presenilin homolog

E. Koo, C. Hong, 1997, Neuroreport.

PERK-mediated induction of microRNA-483 disrupts cellular ATP homeostasis during the unfolded protein response

E. Koo, Jaeseok Han, Jonathan H. Lin, 2019, The Journal of Biological Chemistry.

Potential role of presenilin-regulated signaling pathways in sporadic neurodegeneration

Raphael Kopan, E. Koo, 2004, Nature Medicine.

Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits

K. Chuang, P. Wong, G. Tucker-Kellogg, 2021, Acta neuropathologica communications.

ALZHEIMER’S DISEASE Advances in Genetics, Molecular and Cellular Biology ALZHEIMER’S DISEASE Advances in Genetics, Molecular and Cellular Biology

D. Holtzman, J. Trojanowski, A. Savonenko, 2013 .

Presenilins Mediate Phosphatidylinositol 3-Kinase/AKT and ERK Activation via Select Signaling Receptors

D. Kang, E. Koo, Emanuela Repetto, 2005, Journal of Biological Chemistry.

Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease.

D. Selkoe, W. Xia, E. Koo, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing.

D. Price, K. Beyreuther, A. Unterbeck, 1990, Science.

Substrate-targeting γ-secretase modulators

M. Wolfe, D. Walsh, T. Golde, 2008, Nature.

Cerebral transcriptome analysis reveals age-dependent progression of neuroinflammation in P301S mutant tau transgenic male mice

Hyungwon Choi, T. Arumugam, D. Jo, 2019, Brain, Behavior, and Immunity.

Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP

D. Nižetić, W. Hong, E. Koo, 2015, Front. Behav. Neurosci..

Amyloid β-peptide is produced by cultured cells during normal metabolism

D. Selkoe, D. Teplow, C. Vigo‐Pelfrey, 1992, Nature.

Amyloid beta-peptide is produced by cultured cells during normal metabolism.

D. Teplow, C. Vigo‐Pelfrey, C. Haass, 1992, Nature.

Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis.

B. de Strooper, Hui Zheng, C. Eberhart, 2002, Cell.

Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production

Pritam Das, Sascha Weggen, S. Weggen, 2005, Nature Medicine.

Prevalence of cognitive impairment in Chinese: Epidemiology of Dementia in Singapore study

T. Wong, N. Venketasubramanian, C. Cheung, 2013, Journal of Neurology, Neurosurgery & Psychiatry.

A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor

S. Chandra, L. Ellerby, G. Salvesen, 2000, Nature Medicine.

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor.

S. Chandra, L. Ellerby, G. Salvesen, 2000, Nature medicine.

A pilot proteomic study of amyloid precursor interactors in Alzheimer's disease

B. Gibson, D. Bredesen, C. Link, 2005, Annals of neurology.

Amyloid diseases: abnormal protein aggregation in neurodegeneration.

P. Lansbury, J. Kelly, E. Koo, 1999, Proceedings of the National Academy of Sciences of the United States of America.

NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo

Pritam Das, Jason L. Eriksen, Todd E. Golde, 2003 .

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.

Pritam Das, Sascha Weggen, S. Weggen, 2003, The Journal of clinical investigation.

Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.

R. Katzman., C. Kawas, J. Troncoso, 2000, The Journal of clinical investigation.

Caspase Activation and Caspase-Mediated Cleavage of APP Is Associated with Amyloid β-Protein-Induced Synapse Loss in Alzheimer's Disease.

E. Koo, M. Navarro, H. Nhan, 2020, Cell reports.

APP upregulation contributes to retinal ganglion cell degeneration via JNK3

Xin-Yuan Fu, L. Stanton, W. Hong, 2017, Cell Death & Differentiation.

Trafficking of cell-surface amyloid beta-protein precursor. II. Endocytosis, recycling and lysosomal targeting detected by immunolocalization.

D. Selkoe, E. Koo, T. Yamazaki, 1996, Journal of cell science.

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein.

C. Glass, M. Rosenfeld, S. H. Baek, 2002, Cell.

Protein Kinase C ϵ Suppresses Aβ Production and Promotes Activation of α-Secretase

E. Koo, Dan Wang, T. McMahon, 2001 .

The endocytotic pathway is required for increased A beta 42 secretion during apoptosis.

E. Koo, C. Sodhi, R. Perez, 2004, Brain Research. Molecular Brain Research.

γ-Secretase inhibitors and modulators.

T. Golde, B. Osborne, E. Koo, 2013, Biochimica et biophysica acta.

The Non-cyclooxygenase Targets of Non-steroidal Anti-inflammatory Drugs, Lipoxygenases, Peroxisome Proliferator-activated Receptor, Inhibitor of κB Kinase, and NFκB, Do Not Reduce Amyloid β42 Production*

S. Weggen, T. Golde, E. Koo, 2003, Journal of Biological Chemistry.

Emerging therapeutics for Alzheimer's disease.

E. Koo, K. Chiang, 2014, Annual review of pharmacology and toxicology.

Amyloid in Alzheimer’s Disease and Animal Models

D. Borchelt, D. Price, L. Martin, 1994 .

Differential expression of amyloid precursor protein mRNAs in cases of Alzheimer's disease and in aged nonhuman primates

D. Price, L. Cork, A. Unterbeck, 1990, Neuron.

Alzheimer’s Disease and Animal Models

D. Price, L. Martin, V. Koliatsos, 1990 .

Neuronal responses to injury and aging: lessons from animal models.

D. Price, V. Koliatsos, L. Cork, 1990, Progress in brain research.

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

D. Price, C. Masters, L. Martin, 1990, Proceedings of the National Academy of Sciences of the United States of America.

β-Amyloid gene is not present in three copies in autopsy-validated Alzheimer's disease

D. Price, M. Folstein, S. Antonarakis, 1987 .

Molecular Neurodegeneration BioMed Central Review The amyloid precursor protein: beyond amyloid

Hui Zheng, E. Koo, Hui Zheng, 2006 .

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA

T. Willnow, C. Tischer, E. Koo, 2017, Cellular and Molecular Life Sciences.

Trafficking of cell-surface amyloid beta-protein precursor. I. Secretion, endocytosis and recycling as detected by labeled monoclonal antibody.

S. Squazzo, D. Selkoe, E. Koo, 1996, Journal of cell science.

Aggregation of Secreted Amyloid -Protein into Sodium Dodecyl Sulfate-stable Oligomers in Cell Culture (*)

S. Squazzo, D. Selkoe, D. Teplow, 1995, The Journal of Biological Chemistry.

A calcium-stimulated serine protease from monkey brain degrades the β-amyloid precursor protein

E. Koo, C. Abraham, B. Razzaboni, 1992, Brain Research.

Aluminum neurotoxicity: altered expression of cytoskeletal genes.

D. Price, J. Troncoso, E. Koo, 1988, Brain research.

Short Aβ peptides attenuate Aβ42 toxicity in vivo

D. Borchelt, T. Golde, P. Cruz, 2018, The Journal of experimental medicine.

Amyloid β protein toxicity mediated by the formation of amyloid‐β protein precursor complexes

E. Masliah, D. Bredesen, E. Koo, 2003 .

The Journal of Toxicological Sciences

E. Koo, A. Ebrahimnejad, C. Meschter, 2014 .

Deficits in Synaptic Transmission and Learning in Amyloid Precursor Protein (APP) Transgenic Mice Require C-Terminal Cleavage of APP

S. Heinemann, D. Bredesen, M. Saganich, 2006, The Journal of Neuroscience.

Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers.

Rudolph E. Tanzi, John M. Ringman, Edward H. Koo, 2014, JAMA neurology.

World-wide fingers network: A global approach to risk reduction and prevention of dementia

M. Carrillo, J. Molinuevo, P. Scheltens, 2019, Journal of the Neurological Sciences.

Early and Selective Impairments in Axonal Transport Kinetics of Synaptic Cargoes Induced by Soluble Amyloid β‐Protein Oligomers

Subhojit Roy, Kryslaine Radomski, Utpal Das, 2012, Traffic.

Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift

Todd E. Golde, Lon S. Schneider, Edward H. Koo, 2011, Neuron.

Early BDNF Treatment Ameliorates Cell Loss in the Entorhinal Cortex of APP Transgenic Mice

M. Tuszynski, E. Masliah, E. Rockenstein, 2013, The Journal of Neuroscience.

Visualization of APP and BACE-1 approximation in neurons: new insights into the amyloidogenic pathway

S. Wagner, E. Koo, U. Das, 2015, Nature neuroscience.

Substrate docking to γ-secretase allows access of γ-secretase modulators to an allosteric site

B. Hyman, M. Wolfe, O. Berezovska, 2010, Nature communications.

Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

D. G. Clark, C. Carlson, K. Lunetta, 2015, JAMA neurology.

Modulation of Aβ42 in vivo by γ-secretase modulator in primates and humans

D. Galasko, T. Golde, E. Koo, 2015, Alzheimer's Research & Therapy.

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator

T. Golde, C. Ceballos‐Diaz, E. Koo, 2015, Molecular Neurodegeneration.

The cytoplasmic domain of the LDL receptor‐related protein regulates multiple steps in APP processing

Sascha Weggen, S. Weggen, E. Koo, 2002, The EMBO journal.

To Think or Not to Think: Synaptic Activity and Aβ Release

E. Koo, B. E. Schroeder, 2005, Neuron.

The Amyloidogenic Pathway of Amyloid Precursor Protein (APP) Is Independent of Its Cleavage by Caspases*

S. Chandra, E. Koo, C. Pietrzik, 2001, The Journal of Biological Chemistry.

Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons

D. Selkoe, E. Koo, T. Yamazaki, 1995, The Journal of cell biology.

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide.

P. Greengard, J. Buxbaum, E. Koo, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Nonsteroidal antiinflammatory drugs as therapeutic agents for Alzheimer's disease

S. Weggen, T. Golde, E. Koo, 2002 .

Transcriptional regulation of APP by apoE: To boldly go where no isoform has gone before

E. Koo, Liying Corinne Lee, Michele Q. L. Goh, 2017, BioEssays : news and reviews in molecular, cellular and developmental biology.

Deficiency in either COX-1 or COX-2 genes does not affect amyloid beta protein burden in amyloid precursor protein transgenic mice.

T. Golde, E. Koo, N. Chevallier, 2016, Biochemical and biophysical research communications.

Safety, Tolerability, Pharmacokinetics, and Aβ Levels After Short-term Administration of R-flurbiprofen in Healthy Elderly Individuals

D. Galasko, S. Hendrix, N. Graff-Radford, 2007, Alzheimer disease and associated disorders.

FE65 Constitutes the Functional Link between the Low-Density Lipoprotein Receptor-Related Protein and the Amyloid Precursor Protein

Sascha Weggen, Edward H. Koo, S. Weggen, 2004, The Journal of Neuroscience.

Complex Relationships between Substrate Sequence and Sensitivity to Alterations in γ-Secretase Processivity Induced by γ-Secretase Modulators

T. Golde, P. Cruz, E. Koo, 2014, Biochemistry.

Aged Non‐Human Primates: An Animal Model of Age‐Associated Neurodegenerative Disease

D. Price, M. Wagster, V. Koliatsos, 1991, Brain pathology.

The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes

E. Koo, K. Chiang, H. Nhan, 2014, Acta Neuropathologica.

Evidence That Nonsteroidal Anti-inflammatory Drugs Decrease Amyloid β42 Production by Direct Modulation of γ-Secretase Activity*

S. Weggen, T. Golde, E. Koo, 2003, Journal of Biological Chemistry.

Activity-Induced Convergence of APP and BACE-1 in Acidic Microdomains via an Endocytosis-Dependent Pathway

E. Koo, U. Das, Subhojit Roy, 2013, Neuron.

The Role of APP Processing and Trafficking Pathways in the Formation of Amyloid β‐Protein a

D. Selkoe, D. Teplow, M. Citron, 1996 .

The role of APP processing and trafficking pathways in the formation of amyloid beta-protein.

D. Selkoe, D. Teplow, M. Citron, 1996, Annals of the New York Academy of Sciences.

Amyloid accumulation drives proteome-wide alterations in mouse models of Alzheimer’s disease like pathology

Daniel B. McClatchy, J. Yates, Anirvan Ghosh, 2017, bioRxiv.

Aβ-induced synaptic injury is mediated by presynaptic expression of amyloid precursor protein (APP) in hippocampal neurons

L. Luo, Mark Ellisman, E. Bushong, 2020, bioRxiv.

Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain

D. Kang, E. Bianchi, E. Koo, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Alzheimer β/A4‐Amyloid Precursor Protein: Evidence for Putative Amyloidogenic Fragment

P. Greengard, D. Price, S. Gandy, 1992, Journal of neurochemistry.

SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study

E. Chew, Christopher L H Chen, C. Henry, 2021, Alzheimer's & dementia.

Aβ induces cell death by direct interaction with its cognate extracellular domain on APP (APP 597–624)

D. Bredesen, E. Koo, M. Kummer, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Lysine 624 of the Amyloid Precursor Protein (APP) Is a Critical Determinant of Amyloid β Peptide Length

T. Golde, B. Cottrell, E. Koo, 2011, The Journal of Biological Chemistry.

APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission

M. Korte, J. Stephan, E. Koo, 2017, The Journal of Neuroscience.

Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

K. Blennow, H. Zetterberg, E. Koo, 2023, Acta Neuropathologica Communications.

β‐Amyloid Protein is Higher in Alzheimer's Disease Brains: Description of a Quantitative Biochemical Assay

E. Koo, S. Frucht, 1993, Journal of neuropathology and experimental neurology.

Enhanced cleavage of APP by co-expressed Bace1 alters the distribution of APP and its fragments in neuronal and non-neuronal cells

E. Koo, G. Thinakaran, Jonathan Aow, 2022, Molecular Neurobiology.

APP upregulation contributes to retinal ganglion cell degeneration via JNK3

K. Lim, Xin-Yuan Fu, L. Stanton, 2017, Cell Death & Differentiation.

Developmental expression of alpha 1-antichymotrypsin in brain may be related to astrogliosis.

D. Price, L. Cork, E. Koo, 1991, Neurobiology of aging.

Sequences from the Low Density Lipoprotein Receptor-related Protein (LRP) Cytoplasmic Domain Enhance Amyloid β Protein Production via the β-Secretase Pathway without Altering Amyloid Precursor Protein/LRP Nuclear Signaling*

D. Kang, E. Koo, C. Pietrzik, 2005, Journal of Biological Chemistry.

D. Price, L. Martin, V. Koliatsos, 1991, Clinical neuropharmacology.

The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms.

Hui Zheng, A. Takashima, H. Yamaguchi, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Presenilins mediate PI3K/AKT and ERK activation via select signaling receptors: selectivity of PS2 i

D. Kang, E. Koo, I. Yoon, 2005 .

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator

T. Golde, C. Ceballos‐Diaz, E. Koo, 2015, Molecular Neurodegeneration.

Evidence for a clathrin-independent endocytic pathway for APP internalization in the neuronal somatodendritic compartment

E. Koo, Y. T. Goh, A. Sun, 2023, Cell reports.

New tricks from an old dog: Another synaptotoxic fragment from APP

E. Koo, S. Tyan, 2015, Cell Research.

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Margaret A. Pericak-Vance, John X. Morris, Jonathan L. Haines, 2012, Neurology.

Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP

D. Nižetić, W. Hong, E. Koo, 2015, Front. Behav. Neurosci..

PERK-mediated induction of microRNA-483 disrupts cellular ATP homeostasis during the unfolded protein response.

E. Koo, Jaeseok Han, Jonathan H. Lin, 2020, Journal of Biological Chemistry.

APP family member dimeric complexes are formed predominantly in synaptic compartments

E. Koo, S. Kins, U. Müller, 2023, Cell & Bioscience.

PS1 Interacts With and Facilitates β-Catenin Turnover

D. Kang, E. Koo, S. Soriano, 2002 .

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

D. G. Clark, Jason J. Corneveaux, C. Carlson, 2014, JAMA neurology.

To think or not to think: synaptic activity and Abeta release.

E. Koo, B. E. Schroeder, 2005, Neuron.

Characterization of amyloid beta protein species in cerebral amyloid angiopathy of a squirrel monkey by immunocytochemistry and enzyme-linked immunosorbent assay.

H. Mori, A. Tamaoka, S. Shoji, 1997, Brain research.

The Effects of Aging on Proteasome Activity , Assembly , and Abundance in C . elegans

S. Diego, M. Hetzer, A. Dillin, 2012 .

Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.

C. Carlson, K. Lunetta, D. Geschwind, 2015, JAMA neurology.

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

John X. Morris, Jason J. Corneveaux, Asha A. Nair, 2012, Neurology.

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

D. G. Clark, Jason J. Corneveaux, C. Carlson, 2014, JAMA neurology.

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA

T. Willnow, C. Tischer, E. Koo, 2017, Cellular and Molecular Life Sciences.

World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia

M. Carrillo, J. Molinuevo, P. Scheltens, 2020, Alzheimer's & dementia : the journal of the Alzheimer's Association.

Quantitative magnetic resonance morphometry of extraocular muscles: a new diagnostic tool in paralytic strabismus.

J. M. Miller, J. Demer, A. Rosenbaum, 1994, Journal of pediatric ophthalmology and strabismus.

Neurodegenerative Diseases: What Is to Be Done?

D. Holtzman, L. Mucke, E. Masliah, 2015 .

SINGAPORE INTERVENTION STUDY TO PREVENT COGNITIVE IMPAIRMENT AND DISABILITY (SINGER) INITIATIVE

E. Chew, Christopher L H Chen, C. Henry, 2017, Alzheimer's & Dementia.