P. Scott

P. Scott, E. Tredget, A. Armour, 2007, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Chapter 47 – Molecular and cellular basis of hypertrophic scarring

A. Ghahary, P. Scott, E. Tredget, 2007 .

Immunohistochemical localization of the proteoglycans decorin, biglycan and versican and transforming growth factor‐β in human post‐burn hypertrophic and mature scars

A. Ghahary, P. Scott, E. Tredget, 1995, Histopathology.

Ultrastructure of the bovine temporomandibular joint disc.

P. Scott, I. Kuc, 1994, Archives of oral biology.

An immunohistochemical study of the localization of biglycan, decorin and large chondroitin-sulphate proteoglycan in adult rat temporomandibular joint disc.

H. Mitani, Y. Sasano, P. Scott, 1998, Archives of oral biology.

The cyanogen bromide peptides of bovine soluble and insoluble collagens. II. Tissue specific cross-linked peptides of insoluble skin and dentin collagen.

P. Scott, A. Veis, 1976, Connective tissue research.

On the calculation of the binding force between decorin and collagen.

J. Bella, P. Scott, P. Bishop, 2006, Journal of biomechanics.

Control of wound contraction. Basic and clinical features.

A. Ghahary, P. Scott, E. Tredget, 2000, Hand clinics.

Healing of burn wounds in transgenic mice overexpressing transforming growth factor-beta 1 in the epidermis.

A. Ghahary, P. Scott, E. Tredget, 2001, The American journal of pathology.

Polarized Th2 cytokine production in patients with hypertrophic scar following thermal injury.

M. Delehanty, P. Scott, E. Tredget, 2006, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

The JCR:LA‐cp rat: A novel model for impaired wound healing

A. Ghahary, P. Scott, E. Tredget, 2004, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Identification of fibrocytes in postburn hypertrophic scar

A. Ghahary, P. Scott, E. Tredget, 2005, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Isolation and characterization of small proteoglycans from different zones of the porcine knee meniscus.

P. Scott, T. Nakano, C. Dodd, 1997, Biochimica et biophysica acta.

Latent and active transforming growth factor beta1 released from genetically modified keratinocytes modulates extracellular matrix expression by dermal fibroblasts in a coculture system.

A. Ghahary, P. Scott, E. Tredget, 2002, The Journal of investigative dermatology.

Mannose-6-Phosphate/IGF-II Receptors Mediate the Effects of IGF-1-Induced Latent Transforming Growth Factor β1 on Expression of Type I Collagen and Collagenase in Dermal Fibroblasts

A. Ghahary, P. Scott, E. Tredget, 2000, Growth factors.

Stress-relaxation and contraction of a collagen matrix induces expression of TGF-β and triggers apoptosis in dermal fibroblasts

M. Varedi, A. Ghahary, P. Scott, 2000 .

The Effect of Interferon-a 2 b on an In Vitro Model of Dupuytren ’ s Contracture

A. Ghahary, P. Scott, E. Tredget, 1999 .

The effect of interferon-α2b on an in vitro model of Dupuytren's contracture

A. Ghahary, P. Scott, E. Tredget, 1999 .

IFN-alpha2b suppresses the fibrogenic effects of insulin-like growth factor-1 in dermal fibroblasts.

A. Ghahary, P. Scott, E. Tredget, 1998, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Fibroblasts from post-burn hypertrophic scar tissue synthesize less decorin than normal dermal fibroblasts.

A. Ghahary, P. Scott, E. Tredget, 1998, Clinical science.

Liposome-associated interferon-alpha-2b functions as an anti-fibrogenic factor for human dermal fibroblasts.

A. Ghahary, P. Scott, E. Tredget, 1997, The Journal of investigative dermatology.

Cytoskeleton regulates expression of genes for transforming growth factor‐β1 and extracellular matrix proteins in dermal fibroblasts

M. Varedi, A. Ghahary, P. Scott, 1997, Journal of cellular physiology.

Alteration in cell morphology triggers transforming growth factor-beta 1, collagenase, and tissue inhibitor of metalloproteinases-I expression in normal and hypertrophic scar fibroblasts.

M. Varedi, M. Varedi, A. Ghahary, 1995, The Journal of investigative dermatology.

Expression of mRNA for transforming growth factor-beta 1 is reduced in hypertrophic scar and normal dermal fibroblasts following serial passage in vitro.

A. Ghahary, P. Scott, E. Tredget, 1994, The Journal of investigative dermatology.

Expression of fibronectin messenger RNA in hypertrophic and normal dermal tissues and in vitro regulation by interferon alfa‐2b

A. Ghahary, P. Scott, E. Tredget, 1993, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Regulation of collagen synthesis and messenger RNA levels in normal and hypertrophic scar fibroblasts in vitro by interferon alfa‐2b

A. Ghahary, P. Scott, E. Tredget, 1993, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Chylomicron and apoB48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome.

P. Scott, S. Proctor, J. Russell, 2007, Biochemical Society transactions.

Development, characterization, and wound healing of the keratin 14 promoted transforming growth factor‐β1 transgenic mouse

A. Ghahary, P. Scott, E. Tredget, 2002, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Effect of interferon‐α2b on guinea pig wound closure and the expression of cytoskeletal proteins in vivo

A. Ghahary, P. Scott, E. Tredget, 1998, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Small Leucine‐Rich Repeat Proteoglycans of Skin

P. Scott, 2008 .

Expression and localization of insulin-like growth factor-1 in normal and post-burn hypertrophic scar tissue in human

A. Ghahary, P. Scott, E. Tredget, 1998, Molecular and Cellular Biochemistry.

Light and X-ray Scattering Show Decorin to Be a Dimer in Solution*

P. Scott, J. Sheehan, P. Bishop, 2003, The Journal of Biological Chemistry.

Peripheral Blood Fibrocytes from Burn Patients: Identification and Quantification of Fibrocytes in Adherent Cells Cultured from Peripheral Blood Mononuclear Cells

J. Giuffre, A. Ghahary, P. Scott, 2002, Laboratory Investigation.

Improved scar in postburn patients following interferon-alpha2b treatment is associated with decreased angiogenesis mediated by vascular endothelial cell growth factor.

P. Scott, E. Tredget, H. Shankowsky, 2008, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Improvement in postburn hypertrophic scar after treatment with IFN-alpha2b is associated with decreased fibrocytes.

P. Scott, E. Tredget, T. Stewart, 2007, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Deep dermal fibroblasts contribute to hypertrophic scarring

P. Scott, E. Tredget, H. Shankowsky, 2008, Laboratory Investigation.

Fibrocytes from burn patients regulate the activities of fibroblasts

P. Scott, E. Tredget, T. Stewart, 2007, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Interferons gamma and alpha‐2b differentially regulate the expression of collagenase and tissue inhibitor of metalloproteinase‐1 messenger RNA in human hypertrophic and normal dermal fibroblasts

A. Ghahary, P. Scott, E. Tredget, 1995, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Partial purification and characterization of a neutral proteinase with collagen telopeptidase activity produced by human gingival fibroblasts.

P. Scott, T. Nakano, 1987, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Increased severity of bleomycin-induced skin fibrosis in mice with leukocyte-specific protein 1 deficiency.

P. Scott, E. Tredget, T. Stewart, 2008, The Journal of investigative dermatology.

Increased TGF‐β–producing CD4+ T lymphocytes in postburn patients and their potential interaction with dermal fibroblasts in hypertrophic scarring

P. Scott, E. Tredget, T. Stewart, 2007, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Enhanced expression of mRNA for transforming growth factor-beta, type I and type III procollagen in human post-burn hypertrophic scar tissues.

A. Ghahary, P. Scott, E. Tredget, 1993, Journal of Laboratory and Clinical Medicine.

Semiquantitative determination of cyanogen bromide peptides of collagen in SDS-polyacrylamide gels.

A. Telser, P. Scott, A. Veis, 1976, Analytical biochemistry.

The cyanogen bromide peptides of bovine soluble and insoluble collagens. I. Characterization of peptides from soluble type I collagen by sodium dodecylsulphate polyacrylamide gel electrophoresis.

P. Scott, A. Veis, 1976, Connective tissue research.

Gas chromatography-mass spectrometry determination of 18O2 in 18O-labelled 4-hydroxyproline for measurement of collagen synthesis and intracellular degradation.

J. F. Burke, A. Ghahary, P. Scott, 1993, Journal of chromatography.

Structural correlations in the family of small leucine-rich repeat proteins and proteoglycans.

P. McEwan, J. Bella, P. Scott, 2006, Journal of structural biology.

Monoclonal antibody to the aminotelopeptide of type II collagen: loss of the epitope after stromelysin digestion.

P. Scott, R. Mayne, M. Accavitti, 1994, Connective tissue research.

Synthesis of tritium-labelled N tau-methylhistamine for the improvement of extraction efficiency of N tau-methylhistamine from biological fluids.

P. Scott, E. Tredget, T. Iwashina, 1997, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Proteomic analysis of human skin fibroblasts grown on titanium: novel approach to study molecular biocompatibility.

P. Scott, J. Wolfaardt, J. Zheng, 2001, Journal of biomedical materials research.

Quantifying the adherence of fibroblasts to titanium and its enhancement by substrate-attached material.

A. Wennerberg, P. Scott, J. Wolfaardt, 2000, Journal of biomedical materials research.

The NH2-terminal amino acid sequence of bovine skin proteodermatan sulfate.

P. Scott, M. Carpenter, C. H. Pearson, 1983, The Journal of biological chemistry.

The Etiology and Management of Hypertrophic Scars and Keloids Following Thermal Injury

A. Ghahary, P. Scott, E. Tredget, 2005 .

Fluorescent‐activated cell‐sorting analysis of intracellular interferon‐γ and interleukin‐4 in fresh and frozen human peripheral blood T‐helper cells

A. Ghahary, M. Delehanty, P. Scott, 2005, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Molecular and cellular aspects of fibrosis following thermal injury.

A. Ghahary, P. Scott, E. Tredget, 2000, Hand clinics.

PARTIAL PURIFICATION AND CHARACTERIZATION OF PROTEODERMATAN SULPHATE-DEGRADING PROTEINASES PRODUCED BY HUMAN GINGIVAL FIBROBLASTS

P. Scott, T. Nakano, 1988 .

Proteoglycans of the articular disc of the bovine temporomandibular joint. II. Low molecular weight dermatan sulphate proteoglycan.

P. Scott, G. Pringle, T. Nakano, 1989, Matrix.

A quantitative chemical study of glycosaminoglycans in the articular disc of the bovine temporomandibular joint.

P. Scott, T. Nakano, 1989, Archives of oral biology.

Bone marrow‐derived stem cells in wound healing: a review

Yaojiong Wu, P. Scott, E. Tredget, 2007, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

The effect of mechanical stress on soft and hard tissue repair; a review.

P. Scott, J. Urschel, H. Williams, 1988, British journal of plastic surgery.

Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan.

Paul G Scott, Jordi Bella, P. McEwan, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A Role for Decorin in the Structural Organization of Periodontal Ligament

Paul G Scott, Renato V Iozzo, H. Larjava, 2000, Laboratory Investigation.

Degradation of Myosin Light Chain in Isolated Rat Hearts Subjected to Ischemia-Reperfusion Injury: A New Intracellular Target for Matrix Metalloproteinase-2

D. Szczesna‐Cordary, R. Schulz, P. Scott, 2005, Circulation.

De novo synthesis of human dermis in vitro in the absence of a three-dimensional scaffold

N. Parenteau, P. Scott, R. Gallo, 2009, In Vitro Cellular & Developmental Biology - Animal.

Human dermal fibroblasts produce nitric oxide and express both constitutive and inducible nitric oxide synthase isoforms.

A. Ghahary, P. Scott, E. Tredget, 1996, The Journal of investigative dermatology.

Increased diameters of collagen fibrils precipitated in vitro in the presence of decorin from various connective tissues.

P. Scott, P G Scott, I M Kuc, 1997, Connective tissue research.

Arnold I. Caplan, Paul G. Scott, D. Heinegård, 2003, The Journal of Biological Chemistry.

A role for disulphide bridges in the protein core in the interaction of proteodermatan sulphate and collagen.

P. Scott, C. Dodd, E. Edwards, 1986, Biochemical and biophysical research communications.

Self-aggregation of bovine skin proteodermatan sulphate promoted by removal of the three N-linked oligosaccharides.

P. Scott, C. Dodd, 1990, Connective tissue research.

Light scattering studies of bovine skin proteodermatan sulfate

P. Scott, A. Jamieson, J. Blackwell, 1989, Biopolymers.

Molecular and Cellular Biology of Derman Fibroproliferative Disorders

A. Ghahary, P. Scott, E. Tredget, 2000 .

Accelerated wound healing in leukocyte‐specific, protein 1‐deficient mouse is associated with increased infiltration of leukocytes and fibrocytes

P. Scott, E. Tredget, T. Stewart, 2007, Journal of leukocyte biology.

The identity of a cyanogen bromide fragment of bovine dentin collagen containing the site of an intermolecular cross-link.

P. Scott, A. Veis, G. Mechanic, 1976, Biochemistry.

The solution conformation of tubulin‐β(422–434)‐NH2 and its Nac‐DATADEQG‐NH2 fragment based on nmr

R. Maccioni, A. Otter, P. Scott, 1991, Biopolymers.

A 1H and 13C NMR study on the role of salt-bridges in the formation of a type I beta-turn in N-acetyl-L-Asp-L-Glu-L-Lys-L-Ser-NH2.

A. Otter, P. Scott, G. Kotovych, 1989, Journal of biomolecular structure & dynamics.

Solution conformation of the type I collagen alpha-1 chain N-telopeptide studied by 1H NMR spectroscopy.

A. Otter, P. Scott, G. Kotovych, 1989, Biochemistry.

Type I collagen alpha-1 chain C-telopeptide: solution structure determined by 600-MHz proton NMR spectroscopy and implications for its role in collagen fibrillogenesis.

A. Otter, P. Scott, G. Kotovych, 1988, Biochemistry.

Spectroscopic study of environment-dependent changes in the conformation of the isolated carboxy-terminal telopeptide of type I collagen.

P. Scott, 1986, Biochemistry.

Hypertrophic scar tissues and fibroblasts produce more transforming growth factor‐β1 mRNA and protein than normal skin and cells

A. Ghahary, P. Scott, E. Tredget, 2000, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

Hypertrophic scars, keloids, and contractures. The cellular and molecular basis for therapy.

A. Ghahary, P. Scott, E. Tredget, 1997, The Surgical clinics of North America.

Changes in the chemical composition of the bovine temporomandibular joint disc with age.

P. Scott, T. Nakano, 1996, Archives of oral biology.

Biochemical and immunohistochemical studies of the protein expression and localization of decorin and biglycan in the temporomandibular joint disc of growing rats.

P. Scott, T. Takuma, I. Mizoguchi, 2002, Archives of oral biology.

The degradation of human dentine collagen by trypsin.

P. Scott, A. Leaver, 1974, Connective tissue research.

Conformational analysis of the type II and type III collagen alpha-1 chain C-telopeptides by 1H NMR and circular dichroism spectroscopy.

J. Cann, A. Otter, P. Scott, 1993, Journal of biomolecular structure & dynamics.

Conformational analysis of the type II and type III collagen α‐1 chain N‐telopeptides by 1H‐NMR spectroscopy and restrained molecular mechanics calculations

A. Otter, P. Scott, G. Kotovych, 1993, Biopolymers.

Crystal Structure of the Biglycan Dimer and Evidence That Dimerization Is Essential for Folding and Stability of Class I Small Leucine-rich Repeat Proteoglycans*

Paul G Scott, P. Scott, J. Sheehan, 2006, Journal of Biological Chemistry.

Determination of 4-hydroxyproline in collagen by gas chromatography/mass spectrometry.

J. F. Burke, P. Scott, E. Tredget, 1990, Analytical biochemistry.

Etiology of late developing incisional hernias--the possible role of mechanical stress.

P. Scott, J. Urschel, H. Williams, 1988, Medical hypotheses.

Experimental wound healing: Increased breaking strength and collagen synthetic activity in abdominal fascial wounds healing with secondary closure of the skin

Bonnie Worth Johnson, P. Scott, Margaret Chambers, 1985, The British journal of surgery.

Glycosaminoglycans and proteoglycans from different zones of the porcine knee meniscus

P. Scott, P G Scott, T. Nakano, 1997, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

An Immunohistochemical Study of the Localization of Biglycan, Decorin and Large Chondroitin-sulphate Proteoglycan in Pleomorphic Adenoma

T. Kaku, P. Scott, F. Rahemtulla, 1999 .

Novel mutations in the small leucine‐rich repeat protein/proteoglycan (SLRP) genes in high myopia

T. Spector, L. Ala‐Kokko, C. Hammond, 2007, Human mutation.

Transforming growth factor-beta mRNA and protein in hypertrophic scar tissues and fibroblasts: antagonism by IFN-alpha and IFN-gamma in vitro and in vivo.

A. Ghahary, P. Scott, E. Tredget, 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Determination of plasma Nτ-methylhistamine in vivo by isotope dilution using benchtop gas chromatography-mass spectrometry

A. Ghahary, P. Scott, E. Tredget, 1997 .

Small proteoglycans from different regions of the fibrocartilaginous temporomandibular joint disc.

P. Scott, T. Nakano, C. Dodd, 1995, Biochimica et biophysica acta.

Purification and characterization of a gelatinase produced by fibroblasts from human gingiva.

P. Scott, T. Nakano, 1986, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Regulation of collagen synthesis and mRNA expression in normal and hypertrophic scar fibroblasts in vitro by interferon-gamma.

A. Ghahary, P. Scott, E. Tredget, 1995, The Journal of surgical research.

Enhanced expression of mRNA for insulin-like growth factor-1 in post-burn hypertrophic scar tissue and its fibrogenic role by dermal fibroblasts

A. Ghahary, P. Scott, E. Tredget, 1995, Molecular and Cellular Biochemistry.

POSTPARTUM CHANGES AND CERTAIN PROPERTIES OF THE PROTEOLYTIC ACTIVITY FROM INVOLUTING RAT UTERUS THAT DEGRADES THE C-TELOPEPTIDE OF TYPE I COLLAGEN

P. Scott, T. Nakano, 1987 .

Nitric oxide synthase expression and nitric oxide production are reduced in hypertrophic scar tissue and fibroblasts.

A. Ghahary, P. Scott, E. Tredget, 1997, The Journal of investigative dermatology.

Cathepsin D: Cleavage of soluble collagen and crosslinked peptides

P. Scott, C. Pearson, 1978, FEBS letters.

Isolation from cultured porcine gingival explants of a neutral proteinase with collagen telopeptidase activity.

P. Scott, H. Goldberg, 1986, Connective tissue research.

Application of a specific radio-immunoassay for the peptide alpha 1CB6 to quantitative studies on intermolecular cross-linking in bovine dentine collagen.

P. Scott, 1982, Connective tissue research.

Cathepsin D: specificity of peptide-bond cleavage in type-I collagen and effects on type-III collagen and procollagen.

P. Scott, H. Pearson, Paul G. Scott, 2005, European journal of biochemistry.

A major intermolecular cross-linking site in bovine dentine collagen involving the alpha 2 chain and stabilizing the 4D overlap.

P. Scott, 1980, Biochemistry.

The isolation of a soluble type III collagen precursor from rat skin.

P. Scott, A. Veis, D. Chyatte, 1975, Biochemical and biophysical research communications.

Liposome associated interferon-alpha-2b functions as an anti-fibrogenic factor in dermal wounds in the guinea pig

A. Ghahary, P. Scott, E. Tredget, 2000, Molecular and Cellular Biochemistry.

The effect of interferon alpha 2b on the expression of cytoskeletal proteins in an in vitro model of wound contraction.

A. Ghahary, P. Scott, E. Tredget, 1995, The Journal of laboratory and clinical medicine.

Proteoglycans of the articular disc of the bovine temporomandibular joint. I. High molecular weight chondroitin sulphate proteoglycan.

P. Scott, T. Nakano, 1989, Matrix.

Skin construct or biological bandage?

P. Scott, EE Tredget, 2005, The Lancet.

Biochemical, biomechanical, and physical changes in the skin in an experimental animal model of therapeutic tissue expansion.

P. Scott, J G Beauchene, M M Chambers, 1989, The Journal of surgical research.

The antifibrogenic effects of liposome-encapsulated IFN-alpha2b cream on skin wounds.

A. Ghahary, P. Scott, E. Tredget, 1999, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Characterization of Opticin and Evidence of Stable Dimerization in Solution*

Paul G Scott, T. Jowitt, P. Scott, 2003, Journal of Biological Chemistry.

Chimeras of bacterial translation factors Tet(O) and EF‐G

P. Scott, N. Thakor, M. Keelan, 2008, FEBS letters.

Protonation‐mediated structural flexibility in the F conjugation regulatory protein, TraM

J. Glover, R. Edwards, L. Frost, 2006, The EMBO journal.

An improved procedure for expression and purification of ribosomal protection protein Tet(O) for high-resolution structural studies.

P. Scott, N. Thakor, Diane E. Taylor, 2007, Protein expression and purification.

Immunolocalization of TGF-beta 1 in human hypertrophic scar and normal dermal tissues.

A. Ghahary, P. Scott, E. Tredget, 1995, Cytokine.

Low intensity pulsed ultrasound stimulates osteogenic differentiation of human gingival fibroblasts

Nesrine Z. Mostafa, T. El-Bialy, M. Doschak, 2008 .