I. Shechter

发表

Structure and regulation of mammalian squalene synthase.

T. Tansey, I. Shechter, T R Tansey, 2000, Biochimica et biophysica acta.

Squalene Synthase, a Determinant of Raft-associated Cholesterol and Modulator of Cancer Cell Proliferation*

F. Claessens, J. Swinnen, P. V. Van Veldhoven, 2007, Journal of Biological Chemistry.

Role of squalene synthase in prostate cancer risk and the biological aggressiveness of human prostate cancer

H Matsui, Kazuto Ito, I. Shechter, 2012, Prostate Cancer and Prostatic Diseases.

Multiple Sequence Elements are Involved in the Transcriptional Regulation of the Human Squalene Synthase Gene*

Timothy F. Osborne, T. Osborne, I. Shechter, 1997, The Journal of Biological Chemistry.

Differential Transcriptional Regulation of the Human Squalene Synthase Gene by Sterol Regulatory Element-binding Proteins (SREBP) 1a and 2 and Involvement of 5′ DNA Sequence Elements in the Regulation*

I. Shechter, G. Guan, P. Dai, 1998, Journal of Biological Chemistry.

Androgens stimulate coordinated lipogenic gene expression in normal target tissues in vivo

T. Roskams, J. Swinnen, I. Shechter, 2003, Molecular and Cellular Endocrinology.

Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages.

P. Edwards, J. Child, I. Shechter, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Inactivation and activation of various membranal enzymes of the cholesterol biosynthetic pathway by digitonin.

I. Shechter, H. Eilenberg, F. Przedecki, 1989, Journal of lipid research.

Regulation of squalene epoxidase activity and comparison of catalytic properties of rat liver and Chinese hamster ovary cell-derived enzymes.

I. Shechter, H. Eilenberg, 1987, Journal of lipid research.

A deficiency of mixed function oxidase activities in the cholesterol biosynthetic pathway of human granulocytes.

I. Shechter, A. Fogelman, G. Popják, 1980, Journal of lipid research.

The metabolism of native and malondialdehyde-altered low density lipoproteins by human monocyte-macrophages.

P. Edwards, I. Shechter, A. Fogelman, 1981, Journal of lipid research.

Enhancement by LDL of transfer of L-4F and oxidized lipids to HDL in C57BL/6J mice and human plasma

S. Reddy, R. Farias-Eisner, S. Imaizumi, 2011, Journal of Lipid Research.

Differential binding of proteins to peroxisomes in rat hepatoma cells: unique association of enzymes involved in isoprenoid metabolism.

T. Tansey, I. Shechter, S. Gupta, 1999, Journal of lipid research.

Low-temperature effect on the sterol-dependent processing of SREBPs and transcription of related genes in HepG2 cells Published, JLR Papers in Press, May 16, 2003. DOI 10.1194/jlr.M300105-JLR200

Sita D Gupta, I. Shechter, B. Boyer, 2003, Journal of Lipid Research.

Comparative squalene synthase gene expression in mouse liver and testis.

T. Tansey, I. Shechter, B. S. Collins, 2001, Archives of biochemistry and biophysics.

The road to squalene synthase.

I. Shechter, 2002, Biochemical and biophysical research communications.

Farnesyl diphosphate synthase is abundantly expressed and regulated by androgen in rat prostatic epithelial cells

Zhou Wang, I. Shechter, Luping Yang, 2001, The Journal of Steroid Biochemistry and Molecular Biology.

Properties of purified rat hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and regulation of enzyme activity.

P. Edwards, I. Shechter, A. Fogelman, 1980, The Journal of biological chemistry.

Regulation of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase. Evidence for thiol-dependent allosteric modulation of enzyme activity.

I. Shechter, J. Roitelman, 1984, The Journal of biological chemistry.

Allosteric and non-allosteric forms of rat liver 3-hydroxy-3-methylglutaryl coenzyme A reductase: differential inhibition of activity by adenosine 2'-monophospho-5'-diphosphoribose.

I. Shechter, J. Roitelman, 1986, Journal of lipid research.

Allosteric activation of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase by nicotinamide adenine dinucleotides.

I. Shechter, J. Roitelman, 1984, The Journal of biological chemistry.

A possible regulatory role of squalene epoxidase in chinese hamster ovary cells

I. Shechter, H. Eilenberg, 1984, Lipids.

Structural requirements for allosteric activators of rat liver microsomal 3-hydroxy-3-methylglutaryl coenzyme A reductase.

I. Shechter, J. Roitelman, 1984, Biochemical and biophysical research communications.

Properties of latent and thiol-activated rat hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase and regulation of enzyme activity.

I. Dotan, I. Shechter, 1983, Archives of biochemistry and biophysics.

Thiol-disulfide-dependent interconversion of active and latent forms of rat hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

I. Dotan, I. Shechter, 1982, Biochimica et biophysica acta.

Localization of the squalene synthase gene (FDFT1) to human chromosome 8p22-p23.1.

I. Shechter, D. Patterson, I. Hart, 1994, Genomics.

Platelet Production of Pathological LDL

P. Edwards, J. Child, I. Shechter, 1980 .

Biosynthesis of gibberellins. IV. Biosynthesis of cyclic diterpenes from trans-geranylgeranyl pyrophosphate.

I. Shechter, C. West, 1969, The Journal of biological chemistry.

Synthesis and Biological Evaluation of Nonionic Prenyl, Geranyl, and Farnesyl Diphosphate Surrogates

I. Shechter, S. Erickson, T. A. Spencer, 1996 .

Zwitterionic Sulfobetaine Inhibitors of Squalene Synthase.

I. Shechter, D. E. Blanchard, T. A. Spencer, 1999, The Journal of organic chemistry.

Function-Structure Studies and Identification of Three Enzyme Domains Involved in the Catalytic Activity in Rat Hepatic Squalene Synthase*

I. Shechter, T. A. Spencer, Y. Ishii, 1998, The Journal of Biological Chemistry.

Comparative properties of 2,3-oxidosqualene-lanosterol cyclase from yeast and liver.

I. Shechter, K. Bloch, F. W. Sweat, 1970, Biochimica et biophysica acta.

Squalene synthase: structure and regulation.

T. Tansey, I. Shechter, 2001, Progress in nucleic acid research and molecular biology.

2.09 – Squalene Synthase

I. Shechter, Gumin Guan, 1999 .

Molecular Cloning and Functional Analysis of the Promoter of the Human Squalene Synthase Gene (*)

I. Shechter, R. Koch, Guojian Jiang, 1995, The Journal of Biological Chemistry.

Occurrence of squalene in methanol-grown bacteria

I. Shechter, I. Goldberg, 1978, Journal of bacteriology.

Characterization of apolipoprotein B mRNA editing from rabbit intestine.

I. Shechter, T. Innerarity, D. Johnson, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.

Robert V Farese, A. Lusis, M. Mehrabian, 1996, Journal of lipid research.

Characterization of farnesyl diphosphate farnesyl transferase 1 (FDFT1) expression in cancer.

G. Hostetter, O. Kallioniemi, S. Mousses, 2019, Personalized medicine.

An efficient method for the synthesis and purification of trans-[14C]geranylgeranyl pyrophosphate.

Y. Gafni, I. Shechter, 1979, Analytical biochemistry.

IDH1 gene transcription is sterol regulated and activated by SREBP-1a and SREBP-2 in human hepatoma HepG2 cells: evidence that IDH1 may regulate lipogenesis in hepatic cells.

I. Shechter, P. Dai, L. Huo, 2003, Journal of lipid research.

Isolation of a kaurene synthetase inhibitor from castor bean seedlings and cell suspension cultures.

Y. Gafni, I. Shechter, 1981, Plant physiology.

Diethylene glycol disulfide from castor bean cell suspension cultures

Y. Gafni, I. Shechter, 1981 .

Comparison between Biosynthesis of ent-Kaurene in Germinating Tomato Seeds and Cell Suspension Cultures of Tomato and Tobacco.

I. Shechter, Y. Yafin, 1975, Plant physiology.

Comparison between Biosynthesis ofent-Kaurene inGerminating TomatoSeedsandCellSuspension Cultures of

I. Shechter, Yitshak Yarn, 1975 .

Solubilization and purification of trans-farnesyl pyrophosphate-squalene synthetase.

I. Shechter, K. Bloch, 1971, The Journal of biological chemistry.

Subcellular localization of squalene synthase in rat hepatic cells. Biochemical and immunochemical evidence.

I. Shechter, S. Krisans, G. Keller, 1993, The Journal of biological chemistry.

cDNA cloning and gene expression analysis of human myo-inositol 1-phosphate synthase.

I. Shechter, P. Dai, Guimin Guan, 2003, Archives of biochemistry and biophysics.

Solubilization, purification, and characterization of a truncated form of rat hepatic squalene synthetase.

I. Shechter, D. B. Weinstein, E. Klinger, 1992, The Journal of biological chemistry.

Structure and function of HDL mimetics.

S. Reddy, G. Anantharamaiah, I. Shechter, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Biosynthesis of trans-farnesyl triphosphate in Gibberella fujikuroi.

I. Shechter, 1973, Biochimica et biophysica acta.

Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids.

C. Le Jossic-Corcos, I. Shechter, C. Gonthier, 2005, The Biochemical journal.

Molecular cloning, expression, and characterization of the cDNA for the rat hepatic squalene synthase.

I. Shechter, J. Straubhaar, D. Conrad, 1992, The Journal of biological chemistry.

Transintestinal transport of the anti-inflammatory drug 4F and the modulation of transintestinal cholesterol efflux[S]

S. Reddy, K. Williams, G. Anantharamaiah, 2016, Journal of Lipid Research.

Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase.

I. Shechter, D. Conrad, T. L. McKenzie, 1993, The Journal of biological chemistry.

Involvement of Farnesyl Protein Transferase (FPTase) in FcεRI-Induced Activation of RBL-2H3 Mast Cells☆

Sita D Gupta, Hua-Tang Chen, I. Shechter, 1999 .

Endotoxin, tumor necrosis factor, and interleukin-1 decrease hepatic squalene synthase activity, protein, and mRNA levels in Syrian hamsters.

K. Feingold, C. Grunfeld, A. Moser, 1997, Journal of lipid research.

SULFOBETAINE ZWITTERIONIC INHIBITORS OF SQUALENE SYNTHASE

I. Shechter, T. A. Spencer, A. Castro, 1996 .

Studies on the catalytic site of rat liver HMG-CoA reductase: interaction with CoA-thioesters and inactivation by iodoacetamide.

I. Shechter, J. Roitelman, Ishaiahu Shechter, 1989, Journal of lipid research.

Fatty Acyl-Coenzyme A Elongation in Brain of Normal and Quaking Mice

I. Shechter, K. Bloch, I. Goldberg, 1973, Science.

Solubilization and purification of trans-farnesyl pyrophosphate-squalene synthetase.

I. Shechter, K. Bloch, 1971, The Journal of biological chemistry.

Solubilization, purification, and characterization of a truncated form of rat hepatic squalene synthetase.

I. Shechter, D. B. Weinstein, E. Klinger, 1992, The Journal of biological chemistry.