I. Rosenkrands

C. Foged, D. Christensen, I. Rosenkrands, 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Subunit vaccines: distearoylphosphatidylcholine-based liposomes entrapping antigen offer a neutral alternative to dimethyldioctadecylammonium-based cationic liposomes as an adjuvant delivery system.

Y. Perrie, S. McNeil, E. Agger, 2011, Journal of pharmaceutical sciences.

Cationic Liposomes Containing Mycobacterial Lipids: a New Powerful Th1 Adjuvant System

P. Andersen, K. Jensen, E. Agger, 2005, Infection and Immunity.

Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6'-dibehenate)-a novel adjuvant inducing both strong CMI and antibody responses.

P. Andersen, Y. Perrie, Daniel J Kirby, 2005, Biochimica et biophysica acta.

A comparative study of cationic liposome and niosome‐based adjuvant systems for protein subunit vaccines: characterisation, environmental scanning electron microscopy and immunisation studies in mice

Y. Perrie, Daniel J Kirby, A. Vangala, 2006, The Journal of pharmacy and pharmacology.

Cationic liposomes as vaccine adjuvants

E. Agger, D. Christensen, K. Korsholm, 2007, Expert review of vaccines.

The increased protection and pathology in Mycobacterium tuberculosis-infected IL-27R-alpha-deficient mice is supported by IL-17A and is associated with the IL-17A-induced expansion of multifunctional T cells

I. Rosenkrands, J. Behrends, C. Hölscher, 2018, Mucosal Immunology.

Detection of proliferative responses to ESAT-6 and CFP-10 by FASCIA assay for diagnosis of Mycobacterium tuberculosis infection.

P. Andersen, I. Julander, I. Rosenkrands, 2011, Journal of immunological methods.

A Chlamydia trachomatis VD1-MOMP vaccine elicits cross-neutralizing and protective antibodies against C/C-related complex serovars

P. Andersen, I. Rosenkrands, Frank Follmann, 2021, NPJ vaccines.

Protective Effect of Vaccine Promoted Neutralizing Antibodies against the Intracellular Pathogen Chlamydia trachomatis

P. Andersen, I. Rosenkrands, Frank Follmann, 2017, Front. Immunol..

Immune Responses to ESAT-6 and CFP-10 by FASCIA and Multiplex Technology for Diagnosis of M. tuberculosis Infection; IP-10 Is a Promising Marker

P. Andersen, I. Julander, I. Rosenkrands, 2012, PloS one.

Higher human CD4 T cell response to novel Mycobacterium tuberculosis latency associated antigens Rv2660 and Rv2659 in latent infection compared with tuberculosis disease.

T. Scriba, G. Hussey, W. Hanekom, 2010, Vaccine.

Analysis of protein species differentiation among mycobacterial low-Mr-secreted proteins by narrow pH range Immobiline gel 2-DE-MALDI-MS.

S. H. Kaufmann, Sabine S. Lange, P. Andersen, 2014, Journal of proteomics.

CFP10 discriminates between nonacetylated and acetylated ESAT‐6 of Mycobacterium tuberculosis by differential interaction

S. H. Kaufmann, E. Müller, P. Andersen, 2004, Proteomics.

Differential Influence of Nutrient-Starved Mycobacterium tuberculosis on Adaptive Immunity Results in Progressive Tuberculosis Disease and Pathology

P. Andersen, Sugata Roy, J. Dietrich, 2015, Infection and Immunity.

In Vivo Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection

M. Behr, P. Andersen, R. Mortensen, 2021, mBio.

In Vivo Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection

M. Behr, P. Andersen, R. Mortensen, 2021, mBio.

Concurrent evaluation of cytokines improves the accuracy of antibodies against Mycobacterium tuberculosis antigens in the diagnosis of active tuberculosis.

Elisa M. Tjon Kon Fat, S. H. Kaufmann, Mahavir Singh, 2022, Tuberculosis.

Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB

S. Kaufmann, P. V. van Helden, A. Crampin, 2016, Thorax.

Diagnostic Performance of Tuberculosis-Specific IgG Antibody Profiles in Patients with Presumptive Tuberculosis from Two Continents

M. Perkins, Mahavir Singh, M. Gennaro, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease.

A. Crampin, H. Dockrell, T. Ottenhoff, 2016, The Journal of infection.

Metabolite changes in blood predict the onset of tuberculosis

Michel R. Klein, Jane Hughes, Gerhard Walzl, 2018, Nature Communications.

Specific Delayed-Type Hypersensitivity Responses to ESAT-6 Identify Tuberculosis-Infected Cattle

P. Andersen, I. Rosenkrands, J. McNair, 2003, Journal of Clinical Microbiology.

PLGA microspheres for the delivery of a novel subunit TB vaccine

Y. Perrie, Daniel J Kirby, E. Agger, 2008, Journal of drug targeting.

A Simple Mycobacterial Monomycolated Glycerol Lipid Has Potent Immunostimulatory Activity1

D. Minnikin, G. Besra, E. Agger, 2009, The Journal of Immunology.

PLGA microspheres for the delivery of a novel subunit TB vaccine.

Y. Perrie, Daniel J Kirby, E. Agger, 2008, Journal of drug targeting.

Memory T Cells Characterized by Multifunctional CD4 Long-Term Protective Immunity Tuberculosis Subunit Vaccination Provides

E. Agger, K. Korsholm, R. Seder, 2009 .

Assessment of T cell response to novel Mycobacterium tuberculosis synthetic overlapping peptides mixtures (Rv2659 and Rv2660) and ESAT-6 in Egyptian patients.

P. Andersen, Abdel-Rahman B Abdel-Ghaffar, I. Rosenkrands, 2014, The Egyptian journal of immunology.

Protection against SARS-CoV-2 transmission by a parenteral prime—Intranasal boost vaccine strategy

J. Bukh, D. Sheward, B. Murrell, 2022, eBioMedicine.

Protection Against Chlamydia trachomatis Infection and Upper Genital Tract Pathological Changes by Vaccine-Promoted Neutralizing Antibodies Directed to the VD4 of the Major Outer Membrane Protein.

P. Andersen, I. Rosenkrands, Frank Follmann, 2015, The Journal of infectious diseases.

Screening and Characterization of Linear B-Cell Epitopes by Biotinylated Peptide Libraries.

I. Rosenkrands, A. Olsen, 2015, Methods in molecular biology.

Novel Generation Mycobacterial Adjuvant Based on Liposome-Encapsulated Monomycoloyl Glycerol from Mycobacterium bovis Bacillus Calmette-Guérin1

D. Minnikin, G. Besra, P. Andersen, 2009, The Journal of Immunology.

Adjuvants Induce Distinct Immunological Phenotypes in a Bovine Tuberculosis Vaccine Model

H. Vordermeier, R. G. Hewinson, P. Andersen, 2009, Clinical and Vaccine Immunology.

Bacillus Calmette-Guérin bovis Mycobacterium Monomycoloyl Glycerol from Based on Liposome-Encapsulated Novel Generation Mycobacterial Adjuvant

D. Minnikin, G. Besra, P. Andersen, 2009 .

Adjuvants induce distinct immunological phenotypes in a cattle

H. Vordermeier, R. G. Hewinson, E. Agger, 2009 .

Bacillus Calmette-guérin Bovis Mycobacterium Monomycoloyl Glycerol from Based on Liposome-encapsulated Novel Generation Mycobacterial Adjuvant

D. Minnikin, G. Besra, P. Andersen, 2022 .

Immunostimulatory Activity Glycerol Lipid Has Potent A Simple Mycobacterial Monomycolated

D. Minnikin, G. Besra, E. Agger, 2008 .

Specific Acquired Resistance in Mice Immunized with Killed Mycobacteria

E. Agger, I. Rosenkrands, K. Weldingh, 2002, Scandinavian journal of immunology.

Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence (TIRF)

L. Jorgensen, D. Christensen, I. Rosenkrands, 2009, Journal of liposome research.

Ag85B-ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection.

T. Ottenhoff, T. Ottenhoff, P. Andersen, 2011, Vaccine.

Multi-component prime-boost Chlamydia trachomatis vaccination regimes induce antibody and T cell responses and accelerate clearance of infection in a non-human primate model

C. Delaugerre, P. McKay, R. Shattock, 2022, Frontiers in Immunology.

Diagnostic Performance of a Seven-marker Serum Protein Biosignature for the Diagnosis 17 of Active TB Disease in African Primary Health Care Clinic Attendees with Signs and 18 Symptoms Suggestive of TB 19 20

A. Crampin, H. Dockrell, T. Ottenhoff, 2020 .

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

Stewart T. Cole, Claudia Sala, Vadim Makarov, 2009, Science.

Deciphering the proteome of the in vivo diagnostic reagent “purified protein derivative” from Mycobacterium tuberculosis

G. Bai, M. Brennan, J. Belisle, 2012, Proteomics.

Characterization of Active Site Structure in CYP121

D. G. Lewis, S. Cole, A. Munro, 2008, Journal of Biological Chemistry.

Two-Dimensional Electrophoresis for Analysis ofMycobacterium tuberculosis Culture Filtrate and Purification and Characterization of Six Novel Proteins

P. Andersen, I. Rosenkrands, K. Weldingh, 1998, Infection and Immunity.

Rescuing ESAT-6 Specific CD4 T Cells From Terminal Differentiation Is Critical for Long-Term Control of Murine Mtb Infection

P. Andersen, R. Mortensen, I. Rosenkrands, 2020, Frontiers in Immunology.

Genome‐wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis

S. Cole, F. Saul, P. Alzari, 2009, Molecular microbiology.

Identifying protective Streptococcus pyogenes vaccine antigens recognized by both B and T cells in human adults and children

J. Christensen, P. Andersen, J. Dietrich, 2016, Scientific Reports.

Assessing the Serodiagnostic Potential of 35 Mycobacterium tuberculosis Proteins and Identification of Four Novel Serological Antigens

P. Andersen, I. Rosenkrands, K. Weldingh, 2005, Journal of Clinical Microbiology.

Mapping and identification of Mycobacterium tuberculosis proteins by two‐dimensional gel electrophoresis, microsequencing and immunodetection

P. Andersen, I. Rosenkrands, W. Florio, 2000, Electrophoresis.

Hypoxic Response of Mycobacterium tuberculosis Studied by Metabolic Labeling and Proteome Analysis of Cellular and Extracellular Proteins

Richard A. Slayden, Clifton E. Barry, P. Andersen, 2002, Journal of bacteriology.

PPE Protein (Rv3873) from DNA Segment RD1 of Mycobacterium tuberculosis: Strong Recognition of Both Specific T-Cell Epitopes and Epitopes Conserved within the PPE Family

T. Ottenhoff, P. Andersen, E. Agger, 2003, Infection and Immunity.

Potassium availability triggers Mycobacterium tuberculosis transition to, and resuscitation from, non-culturable (dormant) states

S. Waddell, P. Butcher, A. Kaprelyants, 2014, Open Biology.

ESAT-6 proteins: protective antigens and virulence factors?

Priscille Brodin, S. Cole, R. Brosch, 2004, Trends in microbiology.

Identification and Characterization of a 29-Kilodalton Protein from Mycobacterium tuberculosis Culture Filtrate Recognized by Mouse Memory Effector Cells

M. Theisen, P. Andersen, I. Rosenkrands, 1998, Infection and Immunity.

A Mycobacterium tuberculosis operon encoding ESAT-6 and a novel low-molecular-mass culture filtrate protein (CFP-10).

B. Gicquel, P. Andersen, I. Rosenkrands, 1998, Microbiology.

Alteration of epitope recognition pattern in Ag85B and ESAT‐6 has a profound influence on vaccine‐induced protection against Mycobacterium tuberculosis

A. Stryhn, J. Dietrich, P. Andersen, 2006, European journal of immunology.

Proteomic Profiling of Mycobacterium tuberculosis Identifies Nutrient-starvation-responsive Toxin–antitoxin Systems

Connie R. Jimenez, Sander R. Piersma, Karin Weldingh, 2013, Molecular & Cellular Proteomics.

Proteomic profiling of the Mycobacterium tuberculosis identifies nutrient

P. Højrup, S. Piersma, P. Andersen, 2013 .

T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection

G. Schoolnik, F. Miedema, D. Tabb, 2023, Nature Medicine.

A flow cytometry‐based assay to determine the phagocytic activity of both clinical and nonclinical antibody samples against Chlamydia trachomatis

J. Dietrich, I. Rosenkrands, Frank Follmann, 2018, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Serpins from wheat grain

S. Rasmussen, I. Rosenkrands, S. Bjørn, 1994, FEBS letters.

The dynamics of immune responses to Mycobacterium tuberculosis during different stages of natural infection: A longitudinal study among Greenlanders

M. Melbye, J. Wohlfahrt, E. Agger, 2017, PloS one.

Introducing the ESAT-6 free IGRA, a companion diagnostic for TB vaccines based on ESAT-6

P. Andersen, Abdel-Rahman B Abdel-Ghaffar, E. Agger, 2017, Scientific Reports.

Comparative Evaluation of Low-Molecular-Mass Proteins fromMycobacterium tuberculosis Identifies Members of the ESAT-6 Family as Immunodominant T-Cell Antigens

P. Andersen, I. Rosenkrands, P. Ravn, 2000, Infection and Immunity.

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells1

P. Andersen, E. Agger, K. Korsholm, 2009, The Journal of Immunology.

A systems serology approach to the investigation of infection-induced antibody responses and protection in trachoma

J. Dietrich, I. Rosenkrands, D. Mabey, 2023, bioRxiv.

A Mycobacterium tuberculosis-specific subunit vaccine that provides synergistic immunity upon co-administration with Bacillus Calmette-Guérin

P. Andersen, R. Mortensen, I. Rosenkrands, 2021, Nature Communications.

Quantitative Protein Profiling of Chlamydia trachomatis Growth Forms Reveals Defense Strategies Against Tryptophan Starvation*

P. Andersen, I. Rosenkrands, N. Heegaard, 2016, Molecular & Cellular Proteomics.

ESAT-6 and CFP-10 in clinical versus environmental isolates of Mycobacterium kansasii.

L. Rigouts, D. van Soolingen, P. Andersen, 2005, The Journal of infectious diseases.

Protective immunity to tuberculosis with Ag85B-ESAT-6 in a synthetic cationic adjuvant system IC31.

E. Agger, C. Andersen, K. Korsholm, 2006, Vaccine.

I. Rosenkrands, J. Behrends, C. Hölscher, 2018, Mucosal Immunology.

A protective, single-visit TB vaccination regimen by co-administration of a subunit vaccine with BCG

R. Mortensen, I. Rosenkrands, C. L. Lindestam Arlehamn, 2023, NPJ vaccines.

RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response

Daniel E. Zak, D. Zak, G. Schoolnik, 2020, Scientific Reports.

13 ESAT-6 and the Mycobacterial ESX Secretion Systems

R. Brosch, P. Andersen, I. Rosenkrands, 2008 .

Liposomes act as stronger sub-unit vaccine adjuvants when compared to microspheres

Y. Perrie, E. Agger, P. Andersen, 2008, Journal of drug targeting.

Identification of Rv0222 from RD4 as a novel serodiagnostic target for tuberculosis.

Mahavir Singh, P. Andersen, I. Rosenkrands, 2008, Tuberculosis.

Mycobacterium tuberculosis secreted protein ESAT-6 interacts with the human protein syntenin-1

Peter Zipfel, S. Cole, P. Zipfel, 2006, Central European Journal of Biology.

Mycobacterium tuberculosis antigen 85B and ESAT-6 expressed as a recombinant fusion protein in Mycobacterium smegmatis elicits cell-mediated immune response in a murine vaccination model.

B. Robertson, U. Kishore, I. Rosenkrands, 2013, Molecular immunology.

Differential T-Cell Recognition of Native and Recombinant Mycobacterium tuberculosis GroES

P. Højrup, Mahavir Singh, P. Andersen, 1999, Infection and Immunity.

A novel adjuvant formulation induces robust Th1/Th17 memory and mucosal recall responses in Non-Human Primates

D. Christensen, V. Contreras, R. LeGrand, 2023, bioRxiv.

Differential Effects of Prior Exposure to Environmental Mycobacteria on Vaccination with Mycobacterium bovis BCG or a Recombinant BCG Strain Expressing RD1 Antigens

S. Cole, T. Garnier, C. Demangel, 2005, Infection and Immunity.

Immunization with Mycobacterium tuberculosis–Specific Antigens Bypasses T Cell Differentiation from Prior Bacillus Calmette–Guérin Vaccination and Improves Protection in Mice

S. Shin, P. Andersen, E. Agger, 2020, The Journal of Immunology.

NIR transmission spectroscopy for rapid determination of lipid and lyoprotector content in liposomal vaccine adjuvant system CAF01.

H. M. Nielsen, J. Rantanen, M. Allesø, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

An attenuated Mycobacterium tuberculosis clinical strain with a defect in ESX-1 secretion induces minimal host immune responses and pathology

D. Sherman, P. Andersen, I. Rosenkrands, 2017, Scientific Reports.

Preparation of Culture Filtrate Proteins from Mycobacterium tuberculosis.

P. Andersen, I. Rosenkrands, 2001, Methods in Molecular Medicine.

Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis

Elisa M. Tjon Kon Fat, A. Crampin, H. Dockrell, 2018, Scientific Reports.

Development of a proof of concept immunochromatographic lateral flow assay for point of care diagnosis of Mycobacterium tuberculosis

P. Andersen, A. Aseffa, I. Rosenkrands, 2013, BMC Research Notes.

A novel Mycobacterium tuberculosis-specific subunit vaccine provides synergistic immunity upon co-administration with Bacillus Calmette-Guérin

P. Andersen, R. Mortensen, I. Rosenkrands, 2021, bioRxiv.

ESAT-6 secretion-independent impact of ESX-1 genes espF and espG1 on virulence of Mycobacterium tuberculosis.

S. Cole, R. Brosch, C. Leclerc, 2011, The Journal of infectious diseases.