Gong Chen

发表

Nitrene-mediated intermolecular N–N coupling for efficient synthesis of hydrazides

Hao Wang, Hoimin Jung, Fangfang Song, 2021, Nature Chemistry.

Improved protocol for indoline synthesis via palladium-catalyzed intramolecular C(sp2)-H amination.

G. He, Gong Chen, Chengxi Lu, 2012, Organic letters.

Halogen-Bond-Promoted Photoactivation of Perfluoroalkyl Iodides: A Photochemical Protocol for Perfluoroalkylation Reactions.

G. He, Gong Chen, Junhua Wang, 2017, Organic letters.

A rapid and sensitive method for chiroptical sensing of α-amino acids via click-like labeling with o-phthalaldehyde and p-toluenethiol

J Zhang, Bo Li, Li Li, 2020, Chemical science.

Construction of Peptide Macrocycles via Palladium-Catalyzed Multiple S-Arylation: An Effective Strategy to Expand the Structural Diversity of Cross-Linkers.

Bo Li, Bo Li, G. He, 2021, Organic letters.

Palladium-Catalyzed Amide-Directed Hydrocarbofunctionalization of 3-Alkenamides with Alkynes

Hao Wang, Fangfang Song, Zi-Long Bai, 2020, ACS Catalysis.

Ruthenium-Catalyzed Pyridine-Directed Aryl C-H Glycosylation with Glycosyl Chlorides.

G. He, Gong Chen, Shaokun Cai, 2022, The Journal of organic chemistry.

Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones

Gong Chen, Z. Xi, Chuanzheng Zhou, 2020, Nature Communications.

Photoredox-mediated Minisci C–H alkylation of N-heteroarenes using boronic acids and hypervalent iodine

G. He, Gong Chen, Peng Liu, 2016, Chemical science.

Efficient alkyl ether synthesis via palladium-catalyzed, picolinamide-directed alkoxylation of unactivated C(sp3)-H and C(sp2)-H bonds at remote positions.

G. He, Gong Chen, Shu‐Yu Zhang, 2012, Journal of the American Chemical Society.

Construction of Complex Macromulticyclic Peptides via Stitching with Formaldehyde and Guanidine.

Dong‐sheng Guo, G. He, Gong Chen, 2022, Journal of the American Chemical Society.

Extendable stapling of unprotected peptides by crosslinking two amines with o-phthalaldehyde

J Zhang, Bo Li, Lan Wang, 2022, Nature Communications.

Copper-catalyzed carboxamide-directed ortho amination of anilines with alkylamines at room temperature.

G. He, Gong Chen, Shu‐Yu Zhang, 2014, Organic letters.

Highly efficient syntheses of azetidines, pyrrolidines, and indolines via palladium catalyzed intramolecular amination of C(sp3)-H and C(sp2)-H bonds at γ and δ positions.

G. He, Gong Chen, Chengxi Lu, 2012, Journal of the American Chemical Society.

Iridium-Catalyzed ortho-C(sp2)-H Amidation of Benzaldehydes with Organic Azides.

Xinmou Wang, G. He, Gong Chen, 2017, The Journal of organic chemistry.

Photoredox-mediated remote C(sp3)–H heteroarylation of free alcohols

G. He, Gong Chen, Guoxing Li, 2018, Chemical science.

Photoredox-Mediated Mono- and Difluorination of Remote Unactivated Methylene C(sp3)-H Bonds of N-Alkyl Sulfonamides.

G. He, Gong Chen, Zhenxiang Zhao, 2021, Organic letters.

A visible-light-promoted radical reaction system for azidation and halogenation of tertiary aliphatic C–H bonds

G. He, Gong Chen, Yaxin Wang, 2016, Chemical science.

Radical-mediated intramolecular β-C(sp3)-H amidation of alkylimidates: facile synthesis of 1,2-amino alcohols.

G. He, Gong Chen, Xue-Qing Mou, 2018, Chemical communications.

Photoredox‐Mediated Minisci Alkylation of N‐Heteroarenes using Carboxylic Acids and Hypervalent Iodine

G. He, Gong Chen, Junhua Wang, 2018 .

A rapid and sensitive method for chiroptical sensing of α-amino acids via click-like labeling with o-phthalaldehyde and p-toluenethiol

J Zhang, Bo Li, Li Li, 2020, Chemical science.

Palladium-catalyzed trifluoroacetate-promoted mono-arylation of the β-methyl group of alanine at room temperature: synthesis of β-arylated α-amino acids through sequential C–H functionalization

G. He, Gong Chen, Shu‐Yu Zhang, 2014 .

Synthesis of reversible PAD4 inhibitors via copper-catalyzed C−H arylation of benzimidazole

Yanming Wang, G. He, Gong Chen, 2019, Science China Chemistry.

Three-component vicinal-diarylation of alkenes via direct transmetalation of arylboronic acids† †Electronic supplementary information (ESI) available. CCDC 1852875 and 1852877. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c9sc02182e

Gong Chen, Dongbing Zhao, Yun Zhang, 2019, Chemical science.

Palladium-catalyzed picolinamide-directed halogenation of ortho C–H bonds of benzylamine substrates

G. He, Gong Chen, Shu‐Yu Zhang, 2014 .

Palladium-catalyzed alkenylation and alkynylation of ortho-C(sp2)-H bonds of benzylamine picolinamides.

G. He, Gong Chen, Yingsheng Zhao, 2012, Organic letters.

Copper-catalyzed ortho-C(sp2)-H amination of benzamides and picolinamides with alkylamines using oxygen as a green oxidant.

Jie Huang, Gong Chen, Qiong Li, 2020, Organic & biomolecular chemistry.

Epimerization of Tertiary Carbon Centers via Reversible Radical Cleavage of Unactivated C(sp3)-H Bonds.

G. He, Gong Chen, Peng Liu, 2018, Journal of the American Chemical Society.

Palladium-Catalyzed β-C–H Arylation of Alkyl Carboxamides with Sterically Hindered Aryl Iodides Using ortho-Sulfinyl Aniline Auxiliaries

G. He, Gong Chen, Fang Gao, 2017 .

Iodination of remote ortho-C-H bonds of arenes via directed S(E)Ar: a streamlined synthesis of tetrahydroquinolines.

G. He, Gong Chen, Shu‐Yu Zhang, 2013, Organic letters.

Use of a readily removable auxiliary group for the synthesis of pyrrolidones by the palladium-catalyzed intramolecular amination of unactivated γ C(sp(3))-H bonds.

G. He, Gong Chen, Shu‐Yu Zhang, 2013, Angewandte Chemie.

Palladium-catalyzed picolinamide-directed alkylation of unactivated C(sp3)-H bonds with alkyl iodides.

G. He, Gong Chen, Shu‐Yu Zhang, 2013, Journal of the American Chemical Society.

Palladium-catalyzed alkylation of ortho-C(sp2)-H bonds of benzylamide substrates with alkyl halides.

Gong Chen, Yingsheng Zhao, 2011, Organic letters.

Asymmetric Synthesis of β-Lactam via Palladium-Catalyzed Enantioselective Intramolecular C(sp3)–H Amidation

P. Liu, G. He, Gong Chen, 2020, ACS Catalysis.

Syntheses and Transformations of α-Amino Acids via Palladium-Catalyzed Auxiliary-Directed sp(3) C-H Functionalization.

G. He, Gong Chen, W. Nack, 2016, Accounts of chemical research.

Synthesis of N-acyl sulfenamides via copper catalysis and their use as S-sulfenylating reagents of thiols

Hao Wang, Zi-Long Bai, G. He, 2022, Nature Communications.

Iridium-Catalyzed Enantioselective C(sp3)-H Amidation Controlled by Attractive Noncovalent Interactions.

Hao Wang, Zi-Long Bai, G. He, 2019, Journal of the American Chemical Society.

A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp3 C−H arylation

G. He, Gong Chen, Peng Liu, 2018, Nature Chemistry.

Photoredox-Mediated Remote C(sp3)-H Heteroarylation of N-Alkyl Sulfonamides.

G. He, Gong Chen, Guoxing Li, 2019, The Journal of organic chemistry.

Palladium-catalysed C−H glycosylation for synthesis of C-aryl glycosides

G. He, Gong Chen, S. An, 2019, Nature Catalysis.

Enantioselective Alkylamination of Unactivated Alkenes under Copper Catalysis.

Hao Wang, G. He, Gong Chen, 2020, Journal of the American Chemical Society.

Photoredox-Mediated Minisci-type Alkylation of N-Heteroarenes with Alkanes with High Methylene Selectivity

G. He, Gong Chen, Guoxing Li, 2018, ACS Catalysis.

Pd-catalyzed monoselective ortho-C-H alkylation of N-quinolyl benzamides: evidence for stereoretentive coupling of secondary alkyl iodides.

G. He, Gong Chen, Shu‐Yu Zhang, 2015, Journal of the American Chemical Society.

Selective Removal of Aminoquinoline Auxiliary by IBX Oxidation.

Gong Chen, Yameng Wan, D. Zheng, 2019, The Journal of organic chemistry.

Pd(0)-Catalyzed Bidentate Auxiliary Directed Enantioselective Benzylic C–H Arylation of 3-Arylpropanamides Using the BINOL Phosphoramidite Ligand

Q. Peng, Hao Wang, G. He, 2018, ACS Catalysis.

Palladium-catalyzed β-C(sp(3))-H arylation of phthaloyl alanine with hindered aryl iodides: synthesis of complex β-aryl α-amino acids.

G. He, Gong Chen, Xuekai Zhang, 2016, Organic & biomolecular chemistry.

Palladium-catalyzed arylation of β-methylene C(sp3)–H bonds at room temperature: desymmetrization of simple cycloalkyl carboxylic acids

G. He, Gong Chen, W. Nack, 2016 .

Stereoselective synthesis of β-alkylated α-amino acids via palladium-catalyzed alkylation of unactivated methylene C(sp3)-H bonds with primary alkyl halides.

G. He, Gong Chen, Shu‐Yu Zhang, 2013, Journal of the American Chemical Society.

Facile benzo-ring construction via palladium-catalyzed functionalization of unactivated sp3 C-H bonds under mild reaction conditions.

Gong Chen, Yujia Wang, B. Landgraf, 2010, Organic letters.

Total synthesis of hibispeptin A via Pd-catalyzed C(sp3)-H arylation with sterically hindered aryl iodides.

G. He, Gong Chen, Shu‐Yu Zhang, 2014, Organic letters.

Palladium-Catalyzed Picolinamide-Directed Acetoxylation of Unactivated γ-C(sp3)H Bonds of Alkylamines

G. He, Gong Chen, Shu‐Yu Zhang, 2014 .

Palladium-catalyzed stereoretentive olefination of unactivated C(sp3)-H bonds with vinyl iodides at room temperature: synthesis of β-vinyl α-amino acids.

G. He, Gong Chen, Shu‐Yu Zhang, 2014, Organic letters.

Synthesis of non-classical heteroaryl C-glycosides via Minisci-type alkylation of N-heteroarenes with 4-glycosyl-dihydropyridines

G. He, Gong Chen, Juan Duan, 2020, Science China Chemistry.

Histidine-Specific Peptide Modification via Visible-Light-Promoted C-H Alkylation.

Gong Chen, Jie Zhao, Ping Wang, 2019, Journal of the American Chemical Society.

Total Synthesis of Mannopeptimycins α and β.

G. He, Gong Chen, Yunpeng Liu, 2016, Journal of the American Chemical Society.

Efficient preparation of β-hydroxy aspartic acid and its derivatives

G. He, Gong Chen, Bo Wang, 2018, Chinese Chemical Letters.

Palladium-Catalyzed Amide-Directed Enantioselective Carboboration of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand

Q. Peng, Hao Wang, Fangfang Song, 2019, ACS Catalysis.

Copper(I)-Catalyzed Enantioselective Intramolecular Aminotrifluoromethylation of O-Homoallyl Benzimidates.

G. He, Gong Chen, Feng Rong, 2019, Organic letters.

Nitrene-Mediated P–N Coupling Under Iron Catalysis

Hao Wang, Fangfang Song, Zi-Long Bai, 2021, CCS Chemistry.

Construction of Natural-Product-Like Cyclophane-Braced Peptide Macrocycles via sp3 C-H Arylation.

Zhijie Chen, G. He, Gong Chen, 2019, Journal of the American Chemical Society.

Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)—H Bonds with Primary Alkyl Halides.

G. He, Gong Chen, Shu‐Yu Zhang, 2014 .

β-Lactam Synthesis via Copper-Catalyzed Directed Aminoalkylation of Unactivated Alkenes with Cyclobutanone O-Benzoyloximes.

G. He, Gong Chen, Xiaoyan Lv, 2021, Organic letters.

Synthesis of 2,3-Fused Indoline Aminals via 4 + 2 Cycloaddition of NH-free Benzazetidines with Indoles

Hao Wang, G. He, Gong Chen, 2018, Chinese Journal of Chemistry.

Benzazetidine synthesis via palladium-catalysed intramolecular C−H amination

P. Liu, G. He, Gong Chen, 2016 .

Stereoselective Synthesis of C ‐Vinyl Glycosides via Palladium‐Catalyzed C−H Glycosylation of Alkenes

G. He, Gong Chen, Qikai Sun, 2021, Angewandte Chemie.

Stereoselective Synthesis of C-Vinyl Glycosides via Palladium-Catalyzed C-H Glycosylation of Alkenes.

G. He, Gong Chen, Qikai Sun, 2021, Angewandte Chemie.

Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated γ C(sp3)—H Bonds.

G. He, Gong Chen, Shu‐Yu Zhang, 2014 .

An Enantioselective Bidentate Auxiliary Directed Palladium-Catalyzed Benzylic C-H Arylation of Amines Using a BINOL Phosphate Ligand.

Hao Wang, G. He, Gong Chen, 2016, Angewandte Chemie.

Palladium-Catalyzed Amide-Directed Enantioselective Hydrocarbofunctionalization of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand.

Q. Peng, Hao Wang, G. He, 2018, Journal of the American Chemical Society.

Activation of perfluoroalkyl iodides by anions: extending the scope of halogen bond activation to C(sp3)–H amidation, C(sp2)–H iodination, and perfluoroalkylation reactions

H. Neumann, M. Beller, Gong Chen, 2023, Chemical science.

Minisci C–H alkylation of N-heteroarenes with aliphatic alcohols via β-scission of alkoxy radical intermediates

G. He, Gong Chen, Guoxing Li, 2019, Organic Chemistry Frontiers.

β-Silicon-effect-promoted intermolecular site-selective C(sp3)-H amination with dirhodium nitrenes.

T. Kawabata, Gong Chen, K. Arai, 2020, Chemical communications.

Streamlined construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation in solution and on DNA†

G. He, Gong Chen, Yixuan Yang, 2021, Chemical science.

Total synthesis of teixobactin and its stereoisomers

G. He, Gong Chen, Qingmin Wang, 2018 .

Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones

Gong Chen, Z. Xi, Chuanzheng Zhou, 2020, Nature Communications.

Highly Efficient Syntheses of Azetidines, Pyrrolidines, and Indolines via Palladium Catalyzed Intramolecular Amination of C(sp3)—H and C(sp2)—H Bonds at γ and δ Positions.

G. He, Gong Chen, Shu‐Yu Zhang, 2012 .

A unified photoredox-catalysis strategy for C(sp3)–H hydroxylation and amidation using hypervalent iodine† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc02773g Click here for additional data file.

G. He, Gong Chen, Peng Liu, 2017, Chemical science.

Postassembly Modifications of Peptides via Metal-Catalyzed C–H Functionalization

G. He, Gong Chen, Guoxing Li, 2020 .

Palladium-catalyzed picolinamide-directed iodination of remote ortho-C−H bonds of arenes: Synthesis of tetrahydroquinolines

Xinmou Wang, G. He, Gong Chen, 2016, Beilstein journal of organic chemistry.

Palladium-Catalyzed Picolinamide-Directed Iodination of Remote ortho-C-H Bonds of Arenes: Synthesis of Tetrahydroquinolines.

Xinmou Wang, G. He, Gong Chen, 2016 .

Radical C-H Arylation of Oxazoles with Aryl Iodides: dppf as an Electron-Transfer Mediator for Cs2CO3.

G. He, Gong Chen, Man Li, 2018, Organic letters.

Synthesis of β-alkynyl α-amino acids via palladium-catalyzed alkynylation of unactivated C(sp3)-H bonds

G. He, Gong Chen, Bo Wang, 2015, Science China Chemistry.

Bioconjugation via Hetero-Selective Clamping of Two Different Amines with ortho-Phthalaldehyde.

Hao-Yang Liu, G. He, Gong Chen, 2022, Angewandte Chemie.

Faculty Opinions recommendation of Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.

Gong Chen, Gong Chen, 2013 .

Palladium-Catalyzed O - and N -Glycosylation with Glycosyl Chlorides

G. He, Gong Chen, S. An, 2020, CCS Chemistry.

Iridium-Catalyzed Intermolecular N—N Coupling for Hydrazide Synthesis Using N-Benzoyloxycarbamates as Acyl Nitrene Precursor

Hao Wang, Fangfang Song, Gong Chen, 2021, Youji huaxue.

Chiral Bicyclo[2.2.2]octane-Fused Cyclopentadienyl Rhodium Complexes: Synthesis and Potential Use in Asymmetric C—H Activation

Gong Chen, Y. Huang, 2021, Chinese Journal of Organic Chemistry.

Synthesis of phenanthridines via palladium-catalyzed picolinamide-directed sequential C–H functionalization

G. He, Gong Chen, Shuyue Zhang, 2013, Beilstein journal of organic chemistry.

Solid Phase Synthesis of Thioether‐linked Peptide Macrocycles via Palladium‐Catalyzed Intramolecular S‐Arylation and S‐Alkenylation

G. He, Gong Chen, Chao Zhang, 2021, Asian Journal of Organic Chemistry.

Palladium-catalyzed alkylation of unactivated C(sp3)-H bonds with primary alkyl iodides at room temperature: Facile synthesis of β-alkyl α-amino acids

G. He, Gong Chen, Shu‐Yu Zhang, 2015 .

G. He, Gong Chen, Peng Liu, 2017, Chemical science.

Palladium-Catalyzed ortho C-H Arylation of Benzaldehydes Using ortho-Sulfinyl Aniline as Transient Auxiliary.

G. He, Gong Chen, Delong Mu, 2018, Chemistry, an Asian journal.

Synthesis of 2‐Deoxy‐ C ‐Glycosides via Iridium‐Catalyzed sp 2 and sp 3 C–H Glycosylation with Unfunctionalized Glycals

G. He, Gong Chen, Qikai Sun, 2021, Chinese Journal of Chemistry.

Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular C(sp3)-H Arylation of N-Methyl Alanine at C-Termini.

G. He, Gong Chen, Zhenxiang Zhao, 2020, Organic letters.

Correction: Photoredox-mediated Minisci C–H alkylation of N-heteroarenes using boronic acids and hypervalent iodine

G. He, Gong Chen, Peng Liu, 2016, Chemical science.

Enantioselective Alkylamination of Unactivated Alkenes under Copper Catalysis.

Hao Wang, G. He, Gong Chen, 2020, Journal of the American Chemical Society.

Construction of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Picolinamide-Directed Intramolecular C(sp2)-H Arylation.

G. He, Gong Chen, Peng Yang, 2020, Organic letters.

Photoredox-mediated remote C(sp3)–H heteroarylation of free alcohols

G. He, Gong Chen, Guoxing Li, 2018, Chemical science.

Palladium‐Catalyzed Picolinamide‐Directed Halogenation of ortho C—H Bonds of Benzylamine Substrates.

Gong Chen, Shu‐Yu Zhang, Chengxi Lu, 2014 .

Stereoselective synthesis of β-alkylated α-amino acids via palladium-catalyzed alkylation of unactivated methylene C(sp3)-H bonds with primary alkyl halides.

Gong Chen, Shu‐Yu Zhang, W. Nack, 2013, Journal of the American Chemical Society.

Suppression of alpha-carbon racemization in peptide synthesis based on a thiol-labile amino protecting group

Gong Chen, Zhen Xi, Yifei Zhou, 2023, Nature communications.

Cooperative Stapling of Native Peptides at Lysine and Tyrosine or Arginine with Formaldehyde.

K. Houk, Gong Chen, Hong-Guang Tang, 2020, Angewandte Chemie.

Teraryl Braces in Macrocycles: Synthesis and Conformational Landscape Remodeling of Peptides.

A. Yudin, Gong Chen, Hua Rong, 2023, Journal of the American Chemical Society.