J. C. Luft

发表

The effect of particle design on cellular internalization pathways

Stephanie E. A. Gratton, J. DeSimone, M. Napier, 2008, Proceedings of the National Academy of Sciences.

Nanoparticle drug loading as a design parameter to improve docetaxel pharmacokinetics and efficacy.

J. DeSimone, J. C. Luft, W. Zamboni, 2013, Biomaterials.

Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT(®) nanoparticle formulation against non-small-cell lung cancer brain metastases.

C. Anders, A. Deal, J. DeSimone, 2016, Nanomedicine.

Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.

C. Perou, David B. Darr, N. Sharpless, 2017, Nano letters.

Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location.

J. DeSimone, C. Pecot, J. C. Luft, 2017, Nano letters.

Biodistribution and Trafficking of Hydrogel Nanoparticles in Adult Mosquitoes

I. Sánchez-Vargas, J. DeSimone, J. C. Luft, 2015, PLoS neglected tropical diseases.

Biodistribution and Toxicity Studies of PRINT Hydrogel Nanoparticles in Mosquito Larvae and Cells

J. DeSimone, J. C. Luft, Paul M. Airs, 2015, PLoS neglected tropical diseases.

RNA replicon delivery via lipid-complexed PRINT protein particles.

G. Owens, Jing Xu, J. DeSimone, 2013, Molecular pharmaceutics.

Synthesis and characterization of monodisperse uniformly shaped respirable aerosols

J. DeSimone, J. C. Luft, B. Maynor, 2013 .

Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft.

M. Walsh, J. DeSimone, M. Napier, 2013, Nanomedicine : nanotechnology, biology, and medicine.

Potent engineered PLGA nanoparticles by virtue of exceptionally high chemotherapeutic loadings.

J. DeSimone, M. Napier, J. C. Luft, 2011, Nano letters.

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

Joseph M. DeSimone, Timothy J. Merkel, Andrew Z. Wang, 2011, Proceedings of the National Academy of Sciences.

Distribution and Cellular Uptake of PEGylated Polymeric Particles in the Lung Towards Cell-Specific Targeted Delivery

J. DeSimone, J. C. Luft, C. Fromen, 2015, Pharmaceutical Research.

Evaluation of drug loading, pharmacokinetic behavior, and toxicity of a cisplatin-containing hydrogel nanoparticle.

J. DeSimone, J. C. Luft, W. Zamboni, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Design of Asymmetric Particles Containing a Charged Interior and a Neutral Surface Charge: Comparative Study on in Vivo Circulation of Polyelectrolyte Microgels

Jing Xu, Joseph M. DeSimone, Kai Chen, 2014, Journal of the American Chemical Society.

Zapped assembly of polymeric (ZAP) nanoparticles for anti-cancer drug delivery.

J. C. Luft, Stuart S. Dunn, M. Parrott, 2019, Nanoscale.

Particle replication in nonwetting templates nanoparticles with tumor selective alkyl silyl ether docetaxel prodrug reduces toxicity.

J. DeSimone, M. Napier, J. C. Luft, 2014, Nano letters.

Pulmonary Delivery of Butyrylcholinesterase as a Model Protein to the Lung.

J. DeSimone, J. C. Luft, C. Fromen, 2016, Molecular pharmaceutics.

One-Step Syntheses of Photocurable Polyesters Based on a Renewable Resource

Devin G. Barrett, T. Merkel, M. Yousaf, 2010 .

A versatile acid-labile linker for antibody–drug conjugates

J. DeSimone, J. C. Luft, Z. Haroon, 2014 .

Role of Linker Length and Antigen Density in Nanoparticle Peptide Vaccine

J. DeSimone, Chintan H. Kapadia, J. C. Luft, 2019, ACS omega.

In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain.

R. Mumper, J. DeSimone, J. C. Luft, 2012, Journal of controlled release : official journal of the Controlled Release Society.

In Vitro and In Vivo Assessment of Targeting Lipid-based Nanoparticles to the Epidermal Growth Factor-Receptor (EGFR) Using a Novel Heptameric Z EGFR Domain

J. DeSimone, J. C. Luft, Dongwook Kim, 2012 .

New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis.

N. Maeda, J. DeSimone, J. C. Luft, 2020, Vascular pharmacology.

Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer

J. Yeh, J. DeSimone, J. C. Luft, 2018, Cancer Chemotherapy and Pharmacology.

Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses.

M. Miley, J. DeSimone, A. D. de Silva, 2018, Bioconjugate chemistry.

The Interplay of Antigen Affinity, Internalization, and Pharmacokinetics on CD44-Positive Tumor Targeting of Monoclonal Antibodies.

Dylan M Glatt, R. Mumper, J. C. Luft, 2016, Molecular pharmaceutics.

Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells.

J. DeSimone, J. C. Luft, C. Fromen, 2016, Nanomedicine : nanotechnology, biology, and medicine.

Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: insight into functional group effects and biological activity.

J. DeSimone, J. C. Luft, Charles J. Bowerman, 2015, Bioorganic & medicinal chemistry.

Low modulus biomimetic microgel particles with high loading of hemoglobin.

William F. M. Daniel, Ashish A. Pandya, T. Merkel, 2012, Biomacromolecules.

Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production

Joseph M. DeSimone, David Shirvanyants, Sue J. Mecham, 2016, PloS one.

Amphiphilic co-networks with moisture-induced surface segregation for high-performance nonfouling coatings.

T. Merkel, J. Callow, M. Callow, 2011, Langmuir : the ACS journal of surfaces and colloids.

Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma

J. Yeh, J. DeSimone, J. C. Luft, 2016, Proceedings of the National Academy of Sciences.

Nanoparticulate immunotherapy for cancer.

J. DeSimone, Chintan H. Kapadia, J. C. Luft, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Mer Receptor Tyrosine Kinase Signaling

B. Varnum, N. Mahajan, K. Guttridge, 2002, The Journal of Biological Chemistry.

Towards programming immune tolerance through geometric manipulation of phosphatidylserine.

Patrick J. Short, J. Ting, J. DeSimone, 2015, Biomaterials.

Pulmonary Delivery of Nanoparticle-Bound Toll-Like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer.

J. Ting, B. Gorentla, J. DeSimone, 2020, ACS nano.

Tumor Presence Induces Global Immune Changes and Enhances Nanoparticle Clearance.

J. Ting, J. DeSimone, J. Bear, 2016, ACS nano.

Reduction Sensitive PEG Hydrogels for Codelivery of Antigen and Adjuvant To Induce Potent CTLs.

J. DeSimone, Chintan H. Kapadia, J. C. Luft, 2016, Molecular pharmaceutics.

Rendering protein-based particles transiently insoluble for therapeutic applications.

Ashish A. Pandya, G. Owens, J. DeSimone, 2012, Journal of the American Chemical Society.

Reductively Responsive Hydrogel Nanoparticles with Uniform Size, Shape, and Tunable Composition for Systemic siRNA Delivery in Vivo.

J. DeSimone, J. C. Luft, J. Baryza, 2015, Molecular pharmaceutics.

Delivery of multiple siRNAs using lipid-coated PLGA nanoparticles for treatment of prostate cancer.

J. Rolland, M. Napier, P. Pohlhaus, 2012, Nano letters.

Synthesis and Characterization of Cetuximab-Docetaxel and Panitumumab-Docetaxel Antibody-Drug Conjugates for EGFR-Overexpressing Cancer Therapy.

Dylan M Glatt, Shamit S. Prabhu, R. Mumper, 2018, Molecular pharmaceutics.

Formulation of High-Performance Dry Powder Aerosols for Pulmonary Protein Delivery

J. C. Luft, E. Wilson, J. Desimone, 2018, Pharmaceutical Research.

Particles for Local Delivery of Proteins Using Intra‐Articular Route

Saad A. Khan, J. C. Luft, Shaomin Tian, 2016, Advanced healthcare materials.

Silylated precision particles for controlled release of proteins.

Ashish A. Pandya, Saad A. Khan, J. C. Luft, 2015, ACS applied materials & interfaces.

Targeted PRINT Hydrogels: The Role of Nanoparticle Size and Ligand Density on Cell Association, Biodistribution, and Tumor Accumulation.

Joseph M DeSimone, Jillian L Perry, J. C. Luft, 2015, Nano letters.