S. Seah

发表

Substrate specificity, substrate channeling, and allostery in BphJ: an acylating aldehyde dehydrogenase associated with the pyruvate aldolase BphI.

Perrin Baker, J. Carere, S. Seah, 2012, Biochemistry.

Investigating the molecular determinants for substrate channeling in BphI-BphJ, an aldolase-dehydrogenase complex from the polychlorinated biphenyls degradation pathway.

Perrin Baker, J. Carere, S. Seah, 2011, Biochemistry.

Identification of a Serine Hydrolase as a Key Determinant in the Microbial Degradation of Polychlorinated Biphenyls*

S. Seah, L. Eltis, G. Labbé, 2000, The Journal of Biological Chemistry.

Comparative Specificities of Two Evolutionarily Divergent Hydrolases Involved in Microbial Degradation of Polychlorinated Biphenyls

S. Seah, L. Eltis, W. Reineke, 2001, Journal of bacteriology.

Characterization of a Phosphotriesterase-Like Lactonase from Sulfolobus solfataricus and Its Immobilization for Disruption of Quorum Sensing

Filomena Ng, S. Seah, Daniel M Wright, 2010, Applied and Environmental Microbiology.

Structural and Kinetic Characterization of the 4-Carboxy-2-hydroxymuconate Hydratase from the Gallate and Protocatechuate 4,5-Cleavage Pathways of Pseudomonas putida KT2440*

S. Seah, S. Mazurkewich, M. Kimber, 2016, The Journal of Biological Chemistry.

Determination of the metal ion dependence and substrate specificity of a hydratase involved in the degradation pathway of biphenyl/chlorobiphenyl

S. Seah, Pan Wang, 2005, The FEBS journal.

Structural and Kinetic Characterization of 4-Hydroxy-4-methyl-2-oxoglutarate/4-Carboxy-4-hydroxy-2-oxoadipate Aldolase, a Protocatechuate Degradation Enzyme Evolutionarily Convergent with the HpaI and DmpG Pyruvate Aldolases*

S. Seah, S. Mazurkewich, M. Kimber, 2010, The Journal of Biological Chemistry.

Characterization of Two Dehydrogenases from Gluconobacter oxydans Involved in the Transformation of Patulin to Ascladiol

S. Seah, Xiu-zhen Li, Edicon T. S. Chan, 2022, Toxins.

Characterization of an Aldolase Involved in Cholesterol Side Chain Degradation in Mycobacterium tuberculosis

S. Seah, S. Gilbert, L. Hood, 2017, Journal of bacteriology.

Single amino acid substitution in Bacillus sphaericus phenylalanine dehydrogenase dramatically increases its discrimination between phenylalanine and tyrosine substrates.

K. Britton, D. Rice, Y. Asano, 2002, Biochemistry.

Structure–function characterization of an aldo–keto reductase involved in detoxification of the mycotoxin, deoxynivalenol

J. Carere, S. Seah, Yan Zhu, 2022, Scientific Reports.

Bacterial Hydratases Involved in Steroid Side Chain Degradation Have Distinct Substrate Specificities

S. Seah, Nadine Abraham, Kurt L. Schroeter, 2022, Journal of bacteriology.

Characterization of Novel Acyl Coenzyme A Dehydrogenases Involved in Bacterial Steroid Degradation

S. Seah, A. J. Stirling, Amanda Ruprecht, 2015, Journal of Bacteriology.

Kinetic analysis of phenylalanine dehydrogenase mutants designed for aliphatic amino acid dehydrogenase activity with guidance from homology-based modelling.

K. Britton, D. Rice, Y. Asano, 2003, European journal of biochemistry.

Heterologous Expression, Purification, and Characterization of an l-Ornithine N5-Hydroxylase Involved in Pyoverdine Siderophore Biosynthesis in Pseudomonas aeruginosa

S. Seah, L. Ge, 2006, Journal of bacteriology.

Microbial detoxification of mycotoxins in food

S. Seah, T. Zhou, Nadine Abraham, 2022, Frontiers in Microbiology.

Rational approaches for engineering novel functionalities in carbon-carbon bond forming enzymes

Perrin Baker, S. Seah, 2012, Computational and structural biotechnology journal.

Functional Characterization of an Aminotransferase Required for Pyoverdine Siderophore Biosynthesis in Pseudomonas aeruginosa PAO1

S. Seah, C. Vandenende, M. Vlasschaert, 2004, Journal of bacteriology.

Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway.

J. Bolin, S. Seah, L. Eltis, 2006, Biochemistry.

Investigation into the Mode of Phosphate Activation in the 4-Hydroxy-4-Methyl-2-Oxoglutarate/4-Carboxy-4-Hydroxy-2-Oxoadipate Aldolase from Pseudomonas putida F1

S. Seah, S. Mazurkewich, 2016, PloS one.

Secretoglobin 1A1 and 1A1A Differentially Regulate Neutrophil Reactive Oxygen Species Production, Phagocytosis and Extracellular Trap Formation

S. Seah, M. E. Clark, D. Bienzle, 2014, PloS one.

Purification and Preliminary Characterization of a Serine Hydrolase Involved in the Microbial Degradation of Polychlorinated Biphenyls*

J. Bolin, S. Seah, L. Eltis, 1998, The Journal of Biological Chemistry.

Characterization of an aldolase-dehydrogenase complex from the cholesterol degradation pathway of Mycobacterium tuberculosis.

J. Carere, S. Seah, S. McKenna, 2013, Biochemistry.

Probing the molecular basis of substrate specificity, stereospecificity, and catalysis in the class II pyruvate aldolase, BphI.

Perrin Baker, J. Carere, S. Seah, 2011, Biochemistry.

Purification and biochemical characterization of a pyruvate-specific class II aldolase, HpaI.

S. Seah, Weijun Wang, 2005, Biochemistry.

Amino Acid Dehydrogenases

S. Seah, 2007 .

Biochemical and structural analysis of RraA proteins to decipher their relationships with 4-hydroxy-4-methyl-2-oxoglutarate/4-carboxy-4-hydroxy-2-oxoadipate aldolases.

S. Seah, S. Mazurkewich, Weijun Wang, 2014, Biochemistry.

Crystal Structure of Reaction Intermediates in Pyruvate Class II Aldolase

Jurgen Sygusch, J. Sygusch, S. Seah, 2012, The Journal of Biological Chemistry.

Rational design of stereoselectivity in the class II pyruvate aldolase BphI.

Perrin Baker, S. Seah, Perrin Baker, 2012, Journal of the American Chemical Society.

The role of a conserved histidine residue in a pyruvate‐specific Class II aldolase

S. Seah, Weijun Wang, 2008, FEBS letters.

Deglycosylation Differentially Regulates Weaned Porcine Gut Alkaline Phosphatase Isoform Functionality along the Longitudinal Axis

Y. Mine, M. Fan, S. Seah, 2023, Pathogens.

Characterization of a C—C Bond Hydrolase from Sphingomonas wittichii RW1 with Novel Specificities towards Polychlorinated Biphenyl Metabolites

S. Seah, C. Whiting, L. Eltis, 2007, Journal of bacteriology.

Protein-protein interactions and substrate channeling in orthologous and chimeric aldolase-dehydrogenase complexes.

Perrin Baker, J. Carere, S. Seah, 2012, Biochemistry.

The Tautomeric Half-reaction of BphD, a C-C Bond Hydrolase

J. Bolin, Pravindra Kumar, S. Seah, 2007, Journal of Biological Chemistry.

Comparison of two metal-dependent pyruvate aldolases related by convergent evolution: substrate specificity, kinetic mechanism, and substrate channeling.

Perrin Baker, S. Seah, Weijun Wang, 2010, Biochemistry.

The steroid side-chain–cleaving aldolase Ltp2–ChsH2DUF35 is a thiolase superfamily member with a radically repurposed active site

S. Seah, M. Vachon, S. Gilbert, 2019, The Journal of Biological Chemistry.

Alteration in relative activities of phenylalanine dehydrogenase towards different substrates by site‐directed mutagenesis

D. Rice, P. Baker, Y. Asano, 1995, FEBS letters.

Heterologous Expression, Purification, and Characterization of an l-Ornithine N5-Hydroxylase Involved in Pyoverdine Siderophore Biosynthesis in Pseudomonas aeruginosa

S. Seah, Li Ge, 2006, Journal of bacteriology.

Characterization of an aldolase-dehydrogenase complex that exhibits substrate channeling in the polychlorinated biphenyls degradation pathway.

Dan Pan, Perrin Baker, J. Carere, 2009, Biochemistry.