N. Yabuta

发表

A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors

Mariette Schrier, C. C. Sage, Remco Nagel, 2006, Cell.

GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase

H. Nojima, N. Yabuta, K. Fukushima, 2017, Cell cycle.

A novel Chk1/2–Lats2–14-3-3 signaling pathway regulates P-body formation in response to UV damage

Moshe Oren, Hiroshi Nojima, M. Oren, 2011, Journal of Cell Science.

The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.

Janet Rossant, Hiroshi Nojima, Hiroshi Kiyonari, 2009, Developmental cell.

The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1.

M. Oren, E. Lapi, Xin Lu, 2010, Genes & development.

HsMCM6: a new member of the human MCM/P1 family encodes a protein homologous to fission yeast Mis5

Y. Endo, K. Tamura, H. Tsuruga, 1997, Genes to cells : devoted to molecular & cellular mechanisms.

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.

Reuven Agami, Hiroshi Nojima, Mariette Schrier, 2006, Cell.

Electron microscopic observation and single-stranded DNA binding activity of the Mcm4,6,7 complex.

H. Nojima, Y. Uchiyama, N. Yabuta, 2000, Journal of molecular biology.

Tisp40, a spermatid specific bZip transcription factor, functions by binding to the unfolded protein response element via the Rip pathway

H. Nojima, Y. Nishimune, N. Yabuta, 2005, Genes to cells : devoted to molecular & cellular mechanisms.

Oleamide derivatives suppress the spontaneous metastasis by inhibiting connexin 26

M. Yutsudo, H. Nojima, Y. Kita, 2007, International journal of cancer.

Ficolin-1 is a promising therapeutic target for autoimmune diseases

T. Hirano, H. Nojima, N. Ohno, 2018, International immunology.

GAK, a regulator of clathrin‐mediated membrane trafficking, localizes not only in the cytoplasm but also in the nucleus

H. Nojima, N. Yabuta, J. Sato, 2009, Genes to cells : devoted to molecular & cellular mechanisms.

Structure, expression, and chromosomal localization of human GAK.

Y. Endo, H. Tsuruga, H. Nojima, 1997, Genomics.

A Functional Interaction between Hippo-YAP Signaling and FoxO1 Mediates the Oxidative Stress Response

H. Nojima, D. Lim, J. Sadoshima, 2014, Nature Communications.

A Functional Interaction between Hippo-YAP Signaling and FoxO1 Mediates the Oxidative Stress Response

H. Nojima, D. Lim, J. Sadoshima, 2014, Nature Communications.

LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells

M. Kogo, H. Nojima, M. Okada, 2022, Scientific Reports.

Modest static pressure suppresses columnar epithelial cell proliferation in association with cell shape and cytoskeletal modifications

D. Okuzaki, Takao Inoue, N. Yabuta, 2017, bioRxiv.

Lats2 phosphorylates p21/CDKN1A after UV irradiation and regulates apoptosis

M. Oren, N. Okada, H. Nojima, 2013, Journal of Cell Science.

Lats2 Is a Negative Regulator of Myocyte Size in the Heart

W. Tao, H. Nojima, J. Sadoshima, 2008, Circulation research.

N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability

M. Ikawa, M. Okabe, N. Okada, 2013, Journal of Cell Science.

The centrosomal protein Lats2 is a phosphorylation target of Aurora‐A kinase

K. Tamai, H. Nojima, Susumu Suzuki, 2004, Genes to cells : devoted to molecular & cellular mechanisms.

Late cornified envelope 1C (LCE1C), a transcriptional target of TAp63 phosphorylated at T46/T281, interacts with PRMT5

H. Nojima, D. Okuzaki, N. Yabuta, 2018, Scientific Reports.

RECS1 deficiency in mice induces susceptibility to cystic medial degeneration.

S. Yamashita, Y. Matsuzawa, M. Ikawa, 2006, Genes & genetic systems.

Large tumor suppressors 1 and 2 regulate Aurora-B through phosphorylation of INCENP to ensure completion of cytokinesis

H. Nojima, N. Yabuta, Y. Kato, 2016, Heliyon.

Recruitment of cyclin G2 to promyelocytic leukemia nuclear bodies promotes dephosphorylation of γH2AX following treatment with ionizing radiation

M. Ikawa, H. Nojima, N. Yabuta, 2013, Cell cycle.

Atg5-mediated autophagy controls apoptosis/anoikis via p53/Rb pathway in naked mole-rat fibroblasts.

S. Nada, M. Okada, K. Kajiwara, 2020, Biochemical and biophysical research communications.

Expression, nuclear localization and interactions of human MCM/P1 proteins.

Y. Endo, H. Tsuruga, H. Nojima, 1997, Biochemical and biophysical research communications.

Mammalian Mcm2/4/6/7 complex forms a toroidal structure

H. Nojima, Y. Uchiyama, N. Yabuta, 2003, Genes to cells : devoted to molecular & cellular mechanisms.

A simple and efficient method for the preparation of live leukocytes from peripheral blood using the LeukoCatch TM system

H. Nojima, D. Okuzaki, N. Yabuta, 2012 .

A simple and efficient method for the preparation of live leukocytes from peripheral blood using the LeukoCatch TM system

H. Nojima, D. Okuzaki, N. Yabuta, 2012 .

The testes‐specific bZip type transcription factor Tisp40 plays a role in ER stress responses and chromatin packaging during spermiogenesis

M. Ikawa, M. Okabe, H. Nojima, 2006, Genes to cells : devoted to molecular & cellular mechanisms.

Lats1 suppresses centrosome overduplication by modulating the stability of Cdc25B

T. Abe, H. Nojima, N. Yabuta, 2015, Scientific Reports.

Clathrin heavy chain phosphorylated at T606 plays a role in proper cell division

M. Kogo, H. Nojima, N. Yabuta, 2019, Cell cycle.

Expression Profiling of PBMC-based Diagnostic Gene Markers Isolated from Vasculitis Patients

H. Onda, Kazuo Suzuki, H. Hashimoto, 2008, DNA research : an international journal for rapid publication of reports on genes and genomes.

The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis

N. Okada, H. Nojima, Y. Aylon, 2011, Cell cycle.

Isolation and expression profiling of genes upregulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients.

H. Onda, T. Ochi, H. Nojima, 2006, DNA research : an international journal for rapid publication of reports on genes and genomes.

Hippo in Cell Cycle and Mitosis

H. Nojima, N. Yabuta, 2013 .

AJUBA LIM Proteins Limit Hippo Activity in Proliferating Cells by Sequestering the Hippo Core Kinase Complex in the Cytosol

G. Longmore, N. Yabuta, Andrew J. Loza, 2016, Molecular and Cellular Biology.

ELAS1-mediated inhibition of the cyclin G1–B'γ interaction promotes cancer cell apoptosis via stabilization and activation of p53

H. Nojima, N. Yabuta, Y. Naito, 2015, Oncogene.

Cyclin G-associated kinase regulates protein phosphatase 2A by phosphorylation of its B'γ subunit

H. Nojima, N. Yabuta, Y. Naito, 2012, Cell cycle.

Cell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2F

Kiyoshi Ohtani, Hiroshi Nojima, Masataka Nakamura, 1999, Oncogene.

Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice.

Satoshi O. Suzuki, K. Mimori, T. Mak, 2012, The Journal of clinical investigation.

Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation

M. Nieto, E. Rodríguez-Aznar, H. Nojima, 2012, The EMBO journal.

Lats2 Is an Essential Mitotic Regulator Required for the Coordination of Cell Division*

M. Ikawa, M. Okabe, N. Okada, 2007, Journal of Biological Chemistry.

A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization.

M. Oren, D. Michael, H. Nojima, 2006, Genes & development.

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP

H. Nojima, Kyung-suk Choi, N. Yabuta, 2015, Genes & development.

Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation

V. Rotter, M. Oren, H. Nojima, 2009, Oncogene.

Title Structure , Expression , and Chromosome Mapping of LATS 2 , a Mammalian Homologue of the Drosophila Tumor Suppressor Gene lats / warts

N. Copeland, D. Gilbert, N. Jenkins, 2022 .

Isolation and characterization of the TIGA genes, whose transcripts are induced by growth arrest

H. Onda, K. Tamai, H. Nojima, 2006, Nucleic acids research.

Yes-associated Protein Isoform 1 (Yap1) Promotes Cardiomyocyte Survival and Growth to Protect against Myocardial Ischemic Injury*

H. Nojima, J. Sadoshima, P. Zhai, 2012, The Journal of Biological Chemistry.

Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2

E. Morii, H. Nojima, J. Ikeda, 2016, Scientific Reports.

Neonatal Lethality in Knockout Mice Expressing the Kinase-Dead Form of the Gefitinib Target GAK Is Caused by Pulmonary Dysfunction

H. Nojima, N. Yabuta, Y. Naito, 2011, PloS one.

ELAS1 induces apoptotic death in adenocarcinoma DU145 and squamous-cell carcinoma SAS cancer cells, but not in normal KD cells

M. Kogo, H. Nojima, N. Yabuta, 2017, Oncotarget.

Cyclin G2: A novel independent prognostic marker in pancreatic cancer.

H. Eguchi, H. Ishii, Y. Doki, 2015, Oncology letters.

MicroRNA-1246 expression associated with CCNG2-mediated chemoresistance and stemness in pancreatic cancer

H. Eguchi, H. Ishii, Y. Doki, 2014, British Journal of Cancer.

LATS2 Positively Regulates Polycomb Repressive Complex 2

Y. Kondo, Y. Ohkawa, H. Nojima, 2016, PloS one.

LeukoCatch, a quick and efficient tool for the preparation of leukocyte extracts from blood

H. Nojima, D. Okuzaki, N. Yabuta, 2011, BMC clinical pathology.

Assignment of the human CDC21 (MCM4) gene to chromosome 8q11.2.

M. Ishidate, H. Tsuruga, H. Nojima, 1997, Genomics.

Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells

H. Nojima, D. Okuzaki, N. Yabuta, 2015, PloS one.

GAK, a regulator of clathrin-mediated membrane traffic, also controls centrosome integrity and chromosome congression

H. Nojima, N. Yabuta, I. Nagamori, 2009, Journal of Cell Science.

Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis

H. Nojima, N. Yabuta, Satomi Mukai, 2015, Cell cycle.

Gefitinib and Luteolin Cause Growth Arrest of Human Prostate Cancer PC-3 Cells via Inhibition of Cyclin G-Associated Kinase and Induction of miR-630

H. Nojima, D. Okuzaki, Takao Inoue, 2014, PloS one.

Modest Static Pressure Suppresses Columnar Epithelial Cell Growth in Association with Cell Shape and Cytoskeletal Modifications

Man Hagiyama, Takao Inoue, D. Okuzaki, 2017, Front. Physiol..

LATS1/2 kinases trigger self-renewal of cancer stem cells in aggressive oral cancer

H. Nojima, M. Nozaki, G. Longmore, 2019, Oncotarget.

FCN1 (M-ficolin), which directly associates with immunoglobulin G1, is a molecular target of intravenous immunoglobulin therapy for Kawasaki disease

H. Nojima, D. Okuzaki, N. Yabuta, 2017, Scientific Reports.

Isolation of cancer cells with augmented spheroid-forming capability using a novel tool equipped with removable filter

M. Kogo, H. Nojima, N. Yabuta, 2018, Oncotarget.

LeukoCatch, a quick and efficient tool for the preparation of leukocyte extracts from blood

H. Nojima, D. Okuzaki, N. Yabuta, 2011 .

GAK, a regulator of clathrin-mediated membrane traffic, also controls centrosome integrity and chromosome congression

H. Nojima, N. Yabuta, I. Nagamori, 2009, Journal of Cell Science.

Lats2 Is a Negative Regulator of Myocyte Size in the Heart

W. Tao, H. Nojima, J. Sadoshima, 2008, Circulation research.

Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts.

N. Yabuta, Nancy A. Jenkins, Yoshitake Nishimune, 2000, Genomics.

Rad24 is essential for proliferation of diploid cells in fission yeast

H. Nojima, D. Okuzaki, N. Yabuta, 2000, FEBS letters.

Toji, S. et al. The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase. Genes Cells 9, 383-397

K. Tamai, H. Nojima, Susumu Suzuki, 2004 .