S. Husain

发表

Protease activation during in vivo pancreatitis is dependent on calcineurin activation.

D. Jain, Ahsan U. Shah, A. Sarwar, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Experimental acute pancreatitis: In vitro models

Abrahim I. Orabi, S. Husain, O. Mareninova, 2015 .

Dynamic Imaging of Pancreatic Nuclear Factor κB (NF-κB) Activation in Live Mice Using Adeno-associated Virus (AAV) Infusion and Bioluminescence*

Shun-qian Jin, K. Prasadan, Abrahim I. Orabi, 2015, The Journal of Biological Chemistry.

Bile Acids Induce Pancreatic Acinar Cell Injury and Pancreatitis by Activating Calcineurin*

Vijay P. Singh, Shun-qian Jin, Yuhuan Luo, 2012, The Journal of Biological Chemistry.

Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.

P. Hegyi, Z. Rakonczay, J. Whitelegge, 2017, Gastroenterology.

A Non-Invasive Method of Quantifying Pancreatic Volume in Mice Using Micro-MRI

K. Bae, K. Tobita, Abrahim I. Orabi, 2014, PloS one.

Preparation of pancreatic acinar cells for the purpose of calcium imaging, cell injury measurements, and adenoviral infection.

Shun-qian Jin, Abrahim I. Orabi, S. Husain, 2013, Journal of visualized experiments : JoVE.

Pancreatic Development

S. Husain, J. Eisses, 2021, Pediatric Gastrointestinal and Liver Disease.

Low pH enhances connexin32 degradation in the pancreatic acinar cell.

S. Husain, F. Gorelick, T. Kolodecik, 2014, American journal of physiology. Gastrointestinal and liver physiology.

1 ETHANOL ENHANCES CARBACHOL-INDUCED PROTEASE ACTIVATION AND ACCELERATES Ca 2 + WAVES IN ISOLATED RAT PANCREATIC ACINI

Yuhuan Luo, Ahsan U. Shah, Abrahim I. Orabi, 2011 .

Dantrolene mitigates caerulein-induced pancreatitis in vivo in mice.

D. Jain, V. Bhandari, Ahsan U. Shah, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Asparagine Synthetase Is Highly Expressed at Baseline in the Pancreas Through Heightened PERK Signaling

R. Bottino, A. Mukherjee, S. Husain, 2019, Cellular and molecular gastroenterology and hepatology.

Measuring Ca2+ dynamics in pancreatic acini using confocal microscopy

Abrahim I. Orabi, S. Husain, M. Nathanson, 2011 .

The ryanodine receptor mediates early zymogen activation in pancreatitis.

Wayne M. Grant, S. Husain, M. Nathanson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Pancreatic Acinar Cell Nuclear Factor κB Activation Because of Bile Acid Exposure Is Dependent on Calcineurin*

T. Jayaraman, Shun-qian Jin, R. Bottino, 2013, The Journal of Biological Chemistry.

Intraductal Infusion of Taurocholate Followed by Distal Common Bile Duct Ligation Leads to a Severe Necrotic Model of Pancreatitis in Mice

J. Ozolek, D. Pociask, Abrahim I. Orabi, 2014, Pancreas.

TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis.

R. Flavell, Yuhuan Luo, Ahsan U. Shah, 2011, Gastroenterology.

Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin.

Ahsan U. Shah, Wayne M. Grant, S. Husain, 2007, American journal of physiology. Gastrointestinal and liver physiology.

CAERULEIN-INDUCED INTRACELLULAR PANCREATIC ZYMOGEN ACTIVATION IS DEPENDENT UPON CALCINEURIN

E. Thrower, Ahsan U. Shah, Wayne M. Grant, 2006 .

Inhibition of nicotinamide phosphoribosyltransferase protects against acute pancreatitis via modulating macrophage polarization and its related metabolites.

Mengya Niu, S. Husain, Yan He, 2021, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Rectal INdomethacin, oral TacROlimus, or their combination for the prevention of post-ERCP pancreatitis (INTRO Trial): Protocol for a randomized, controlled, double-blinded trial.

Vikesh K. Singh, R. Talukdar, V. Akshintala, 2022, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

IP3 Receptor Type 2 Deficiency Is Associated with a Secretory Defect in the Pancreatic Acinar Cell and an Accumulation of Zymogen Granules

Vijay P. Singh, Yuhuan Luo, M. Lowe, 2012, PloS one.

A review of the rationale for the testing of the calcineurin inhibitor tacrolimus for post-ERCP pancreatitis prevention.

R. Poropatich, V. Akshintala, S. Husain, 2022, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Protective Effects of Calcineurin on Pancreatitis in Mice Depend on Cellular Source.

Mengya Niu, S. Husain, D. Yimlamai, 2020, Gastroenterology.

Molecular and cellular regulation of pancreatic acinar cell function

E. Thrower, S. Husain, 2009, Current opinion in gastroenterology.

Molecular basis for pancreatitis

E. Thrower, S. Husain, F. Gorelick, 2008, Current opinion in gastroenterology.

AXL and MERTK receptor tyrosine kinases inhibition protects against pancreatic necrosis via selectively limiting CXCL2-related neutrophil infiltration.

Mengya Niu, S. Husain, Xiuli Zhang, 2022, Biochimica et biophysica acta. Molecular basis of disease.

Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini.

Wayne M. Grant, S. Husain, F. Gorelick, 2007, American journal of physiology. Gastrointestinal and liver physiology.

Transient High Pressure in Pancreatic Ducts Promotes Inflammation and Alters Tight Junctions via Calcineurin Signaling in Mice.

A. Mukherjee, S. Husain, D. Yimlamai, 2018, Gastroenterology.

The Association of Primary Hyperparathyroidism With Pancreatitis

Matthew J. Giefer, Abrahim I. Orabi, S. Husain, 2012, Journal of clinical gastroenterology.

Ryanodine receptors contribute to bile acid-induced pathological calcium signaling and pancreatitis in mice.

Vijay P. Singh, V. Bhandari, Yuhuan Luo, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Exposure to Radiocontrast Agents Induces Pancreatic Inflammation by Activation of Nuclear Factor-κB, Calcium Signaling, and Calcineurin.

Shun-qian Jin, J. Molkentin, R. Bottino, 2015, Gastroenterology.

Drug Metabolizing Enzymes in the Liver

M. Athar, S. Husain, N. Hasan, 1997 .

Ryanodine Receptor

Shun-qian Jin, T. Jayaraman, Abrahim I. Orabi, 2014 .

Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium

D. Stolz, Vijay P. Singh, C. Baty, 2013, PloS one.

Pharmacological and genetic inhibition of calcineurin protects against carbachol-induced pathological zymogen activation and acinar cell injury.

J. Molkentin, Ahsan U. Shah, Abrahim I. Orabi, 2012, American journal of physiology. Gastrointestinal and liver physiology.

The ryanodine receptor is expressed in human pancreatic acinar cells and contributes to acinar cell injury.

Shun-qian Jin, A. Malik, T. Jayaraman, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Ethanol Enhances Carbachol-induced Protease Activation and Accelerates Ca2+ Waves in Isolated Rat Pancreatic Acini*

Yuhuan Luo, Ahsan U. Shah, Abrahim I. Orabi, 2011, The Journal of Biological Chemistry.

Low Extracellular pH Induces Damage in the Pancreatic Acinar Cell by Enhancing Calcium Signaling*

E. Thrower, Ahsan U. Shah, S. Husain, 2010, The Journal of Biological Chemistry.

Cyclic AMP accelerates calcium waves in pancreatic acinar cells.

Ahsan U. Shah, Wayne M. Grant, Alexander J Park, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Risk Factors for Asparaginase-associated Pancreatitis: A Systematic Review

M. Lowe, Abrahim I. Orabi, S. Husain, 2017, Journal of clinical gastroenterology.

The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis

Catherine A. Sugar, C. Sugar, J. Roos, 2019, The Journal of physiology.

Pancreatic cell tracing, lineage tagging and targeted genetic manipulations in multiple cell types using pancreatic ductal infusion of adeno-associated viral vectors and/or cell-tagging dyes

K. Prasadan, S. Husain, G. Gittes, 2014, Nature Protocols.

Valproic Acid Limits Pancreatic Recovery after Pancreatitis by Inhibiting Histone Deacetylases and Preventing Acinar Redifferentiation Programs.

Akif Burak Tosun, John F Eisses, Gustavo K Rohde, 2015, The American journal of pathology.

Pancreatic gene expression during recovery after pancreatitis reveals unique transcriptome profiles

Wei Chen, Kristy Boggs, A. Mukherjee, 2018, Scientific Reports.

Characterisation of a fatty acid and retinol binding protein orthologue from the hookworm Ancylostoma ceylanicum.

Wayne M. Grant, S. Husain, Keke C. Fairfax, 2009, International journal for parasitology.

SMAD3/Stat3 Signaling Mediates β-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis–Related Diabetes

Henry H. Dong, K. Prasadan, S. Husain, 2017, Diabetes.

Targeted Inhibition of Pancreatic Acinar Cell Calcineurin Is a Novel Strategy to Prevent Post-ERCP Pancreatitis

Kristy Boggs, K. Prasadan, Abrahim I. Orabi, 2016, Cellular and molecular gastroenterology and hepatology.

T1816 Protease Activation During In Vivo Pancreatitis Is Dependent Upon Calcineurin Activation

Ahsan U. Shah, Abrahim I. Orabi, Wayne M. Grant, 2009 .

Molecular and cellular mechanisms of pancreatic injury

E. Thrower, S. Husain, F. Gorelick, 2010, Current opinion in gastroenterology.

A Computer-Based Automated Algorithm for Assessing Acinar Cell Loss after Experimental Pancreatitis

Gustavo K. Rohde, John A. Ozolek, Akif Burak Tosun, 2014, PloS one.

The role of asparagine synthetase on nutrient metabolism in pancreatic disease.

Cheng-Yu Tsai, S. Husain, M. Kilberg, 2020, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy

S. Kliewer, D. Mangelsdorf, Genaro Hernandez, 2020, Science Translational Medicine.

Preclinical safety evaluation of calcineurin inhibitors delivered through an intraductal route to prevent post-ERCP pancreatitis demonstrates endocrine and systemic safety.

Cheng-Yu Tsai, R. Bottino, G. Papachristou, 2023, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].

Identification of Newly Committed Pancreatic Cells in the Adult Mouse Pancreas

S. Leach, K. Prasadan, A. Humar, 2017, Scientific Reports.

Cluster of Differentiation 38 (CD38) Mediates Bile Acid-induced Acinar Cell Injury and Pancreatitis through Cyclic ADP-ribose and Intracellular Calcium Release*

Shun-qian Jin, T. Jayaraman, Abrahim I. Orabi, 2013, The Journal of Biological Chemistry.

A supervised learning framework for pancreatic islet segmentation with multi‐scale color‐texture features and rolling guidance filters

Yue Huang, Chi Liu, John F Eisses, 2016, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Dynamic imaging of pancreatic nuclear factor κB (NF-κB) activation in live mice using adeno-associated virus (AAV) infusion and bioluminescence.

Shun-qian Jin, K. Prasadan, Abrahim I. Orabi, 2016, The Journal of Biological Chemistry.

Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin.

Ahsan U. Shah, Wayne M. Grant, S. Husain, 2007 .

Calcineurin mediates bile-acid induced pancreatitis

Vijay P. Singh, Shun-qian Jin, Yuhuan Luo, 2012 .

PNA lectin for purifying mouse acinar cells from the inflamed pancreas

K. Prasadan, S. Husain, G. Gittes, 2016, Scientific Reports.

Pancreatic gene expression during recovery after pancreatitis reveals unique transcriptome profiles

Wei Chen, Kristy Boggs, A. Mukherjee, 2018, Scientific Reports.

SMAD3/Stat3 Signaling Mediates β-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis–Related Diabetes

Henry H. Dong, K. Prasadan, S. Husain, 2017, Diabetes.

Rectal administration of tacrolimus protects against post-ERCP pancreatitis in mice.

R. Poropatich, Cheng-Yu Tsai, R. Bottino, 2023, Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].