Chuan-en Wang

发表

Differential Activities of the Ubiquitin–Proteasome System in Neurons versus Glia May Account for the Preferential Accumulation of Misfolded Proteins in Neurons

Suzanne Tydlacka, Chuan-en Wang, Xuejun Wang, 2008, The Journal of Neuroscience.

N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking

He Li, Shihua Li, Xiao-Jiang Li, 2008, The Journal of Neuroscience.

Ubiquitin-Activating Enzyme Activity Contributes to Differential Accumulation of Mutant Huntingtin in Brain and Peripheral Tissues

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2014, The Journal of Neuroscience.

Species-dependent neuropathology in transgenic SOD1 pigs

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2014, Cell Research.

Paternal duplication of the 11p15 centromeric imprinting control region is associated with increased expression of CDKN1C in a child with Russell–Silver syndrome

M. K. Rudd, Z. Dai, Yuan Xue, 2015, American journal of medical genetics. Part A.

Polyglutamine Expansion Reduces the Association of TATA-binding Protein with DNA and Induces DNA Binding-independent Neurotoxicity*

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2008, Journal of Biological Chemistry.

TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain.

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2014, Human molecular genetics.

Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation.

L. Havel, Chuan-en Wang, Shihua Li, 2011, Human molecular genetics.

Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin

Brendan H. Lee, V. Cerullo, Chuan-en Wang, 2008, The Journal of cell biology.

Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development.

A. Goffinet, F. Tissir, Chuan-en Wang, 2004, Brain research. Developmental brain research.

Systemic tracking of diagnostic function modules for post-menopausal osteoporosis in a differential co-expression network view

Chuan-en Wang, Yuan-Jian Luo, Jinqiang Wang, 2018, Experimental and therapeutic medicine.

Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2014, Proceedings of the National Academy of Sciences.

Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice

A. Orr, Suzanne Tydlacka, Chuan-en Wang, 2008, The Journal of cell biology.

Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

Ji-Yeon Shin, Xiao-Jiang Li, Zhao-Xue Yu, 2005, The Journal of cell biology.

Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2015, Molecular Neurodegeneration.

Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs.

Shihua Li, Wei Li, Zhen Ouyang, 2010, Human molecular genetics.

Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice.

Xingshun Xu, Dongmei Cheng, Junmin Peng, 2008, The Journal of clinical investigation.

Loss of Ahi1 Affects Early Development by Impairing BM88/Cend1-Mediated Neuronal Differentiation

B. Tang, Xingshun Xu, Miao Sun, 2013, The Journal of Neuroscience.

Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments.

He Li, Shihua Li, Xiao-Jiang Li, 2010, Human molecular genetics.

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2009, Proceedings of the National Academy of Sciences.

N-terminal Huntingtin Knock-In Mice: Implications of Removing the N-terminal Region of Huntingtin for Therapy

Miao Sun, Chuan-en Wang, Shihua Li, 2016, PLoS genetics.

Mutant Huntingtin in Glial Cells Exacerbates Neurological Symptoms of Huntington Disease Mice*

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2010, The Journal of Biological Chemistry.

Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.

M. Hayden, A. Orr, Suzanne Tydlacka, 2008, Human molecular genetics.

Polyglutamine expansion of huntingtin impairs its nuclear export

C. Ross, G. Bates, Chuan-en Wang, 2005, Nature Genetics.

Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms

S. Yu, Chuan-en Wang, Shihua Li, 2013, The Journal of cell biology.

Early Parkinson's disease symptoms in α-synuclein transgenic monkeys.

Hong Wang, Chuan-en Wang, Shihua Li, 2015, Human molecular genetics.

Mutant Alpha-Synuclein Causes Age-Dependent Neuropathology in Monkey Brain

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2015, The Journal of Neuroscience.

Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells

Xingshun Xu, H. Yi, He Li, 2012, Cellular and Molecular Life Sciences.

Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2010, Molecular Brain.

Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development.

A. Goffinet, F. Tissir, Chuan-en Wang, 2004, Brain research. Developmental brain research.

Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.

M. Hayden, A. Orr, Suzanne Tydlacka, 2008, Human molecular genetics.

Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development.

A. Goffinet, F. Tissir, Chuan-en Wang, 2004, Brain research. Developmental brain research.

Early Parkinson's disease symptoms in α-synuclein transgenic monkeys.

Hong Wang, Chuan-en Wang, Shihua Li, 2014, Human molecular genetics.

Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2010, Molecular Brain.

Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells

Xingshun Xu, H. Yi, He Li, 2011, Cellular and Molecular Life Sciences.

TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain.

Chuan-en Wang, Shihua Li, Xiao-Jiang Li, 2014, Human molecular genetics.

Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin

Brendan H. Lee, V. Cerullo, Chuan-en Wang, 2008, The Journal of cell biology.