J. Gallo

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Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Xun Hu, Kelly L. Williams, Christopher E. Shaw, 2009, Science.

Brain diseases. Ubiquitous variations in nerves.

J. Gallo, B. Anderton, 1989, Nature.

Cytoplasmic TDP-43 is involved in cell fate during stress recovery

C. Shaw, C. Troakes, B. Rogelj, 2021, Human molecular genetics.

Lack of association between TDP-43 pathology and tau mis-splicing in Alzheimer's disease

T. Hortobágyi, C. Shaw, C. Troakes, 2016, Neurobiology of Aging.

Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells

T. Maniatis, C. Shaw, M. Carrasco, 2014, PloS one.

Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated.

N. Cairns, P. Luthert, D. Hanger, 1991, The Biochemical journal.

Ubiquitin deposits in anterior horn cells in motor neurone disease

M. Swash, P. Leigh, J. Gallo, 1988, Neuroscience Letters.

Dynamic properties of APC-decorated microtubules in living cells.

S. Kaech, A. Matus, S. Lovestone, 2003, Cell motility and the cytoskeleton.

Developmental Changes in τ Phosphorylation: Fetal τ Is Transiently Phosphorylated in a Manner Similar to Paired Helical Filament‐τ Characteristic of Alzheimer's Disease

J. Brion, J. Gallo, B. Anderton, 1993, Journal of neurochemistry.

The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and beta-amyloid in primary rat cortical neuronal cultures.

C. Miller, D. Hanger, J. Brion, 1995, The Biochemical journal.

Focal distortion of the nuclear envelope by huntingtin aggregates revealed by lamin immunostaining

J. Gallo, Virginie Bros-Facer, J. Chapple, 2008, Neuroscience Letters.

Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic

J. Ule, C. Shaw, C. Troakes, 2013, Cell reports.

MOLECULAR AND CELLULAR-CHANGES ASSOCIATED WITH NEUROFIBRILLARY TANGLES AND SENILE PLAQUES

D. Hanger, A. Probst, J. Gallo, 1990 .

Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity.

M. Swash, P. Leigh, H. Whitwell, 1991, Brain : a journal of neurology.

Tau mRNA is present in axonal RNA granules and is associated with elongation factor 1A

K. Anthony, J. Gallo, Tony Malmqvist, 2014, Brain Research.

Tau alternative splicing in familial and sporadic tauopathies.

J. Gallo, M. Niblock, 2012, Biochemical Society transactions.

Ubiquitous variations in nerves

J. Gallo, B. Anderton, 1989, Nature.

Modelling C9ORF72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis and frontotemporal dementia

C. Shaw, F. Hirth, J. Gallo, 2014, Acta Neuropathologica.

Trypanosoma cruzi: cell type dependent distribution of a tubulin domain in mammalian stages.

A. Capron, J. Gallo, A. Ouaissi, 1987, Experimental parasitology.

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

L. Petrucelli, C. Shaw, C. Troakes, 2017, Human molecular genetics.

A UV cross-linking method combined with infrared imaging to analyse RNA–protein interactions

K. Anthony, J. Gallo, C. Spickett, 2017, Biology methods & protocols.

Edinburgh Explorer Allele-Specific Knockdown of ALS-Associated Mutant TDP-43 in Neural Stem Cells Derived from Induced Pluripotent Stem Cells

T. Maniatis, C. Shaw, M. Carrasco, 2018 .

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration

C. Shaw, C. Troakes, S. Al-Sarraj, 2015, Acta Neuropathologica Communications.

A novel somatodendritic marker defined by a peptide derived from the ALS2 protein

P. Leigh, S. Skaper, J. Cooper, 2004, Neuroreport.

Effect of increased glycogen synthase kinase‐3 activity upon the maturation of the amyloid precursor protein in transfected cells

A. Aplin, J. Gallo, J. S. Jacobsen, 1997, Neuroreport.

In Vitro Phosphorylation of the Cytoplasmic Domain of the Amyloid Precursor Protein by Glycogen Synthase Kinase‐3β

A. Aplin, J. Gallo, J. S. Jacobsen, 1996, Journal of neurochemistry.

Effects of FTDP‐17 mutations on the in vitro phosphorylation of tau by glycogen synthase kinase 3β identified by mass spectrometry demonstrate certain mutations exert long‐range conformational changes

S. Lovestone, W. Blackstock, J. Betts, 2001, FEBS letters.

A perturbed network in neurodegeneration

D. Edbauer, J. Gallo, 2022, Science.

Incorporation of NF‐L into keratin filaments in transfected epithelial cells

J. Gallo, B. Anderton, J. Robertson, 1997, Neuroreport.

Actin and spectrin‐like (Mr= 260–240 000) proteins in gregarines

M. Ghazali, P. Gounon, J. Gallo, 1989 .

Stimulation of MAP kinase by v‐raf transformation of fibroblasts fails to induce hyperphosphorylation of transfected tau

S. Lovestone, J. Woodgett, Christopher C. J. Miller, 1995, FEBS letters.

Hsp40 molecules that target to the ubiquitin-proteasome system decrease inclusion formation in models of polyglutamine disease.

J. Uney, M. Cheetham, J. Gallo, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Subcellular sequestration of an antigenically unique β‐tubulin

J. Gallo, E. Précigout, J. Schrével, 1988 .

Distinct patterns of tau-dependent process formation in mammalian cell lines

L. Bruijn, J. Gallo, P. Krishnamurthy, 2004, Neuroreport.

Tubulin expression in trypanosomes

J. Gallo, E. Précigout, Eric Precigout, 1988, Biology of the cell.

Cytoplasmic events in human meiotic arrest as revealed by immunolabelling of spermatocyte proacrosin.

J. Gallo, D. Escalier, A. Viellefond, 1992, Differentiation; research in biological diversity.

Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease

Michelle K. Lupton, A. Singleton, J. Hardy, 2014, Neurobiology of Aging.

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells

Simon Lovestone, James R. Woodgett, S. Lovestone, 1994, Current Biology.

Cellular phosphorylation of tau by GSK-3 beta influences tau binding to microtubules and microtubule organisation.

U. Wagner, C. Miller, J. Gallo, 1996, Journal of cell science.

Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human Neurons

G. Forte, G. Stokin, T. Falzone, 2017, Journal of Neuroscience.

Angiotensin II Induction of Neurite Outgrowth by AT2 Receptors in NG108-15 Cells

J. Gallo, M. de Gasparo, Jean-Marc Gallo, 1996, The Journal of Biological Chemistry.

Activation of the AT2 Receptor of Angiotensin II Induces Neurite Outgrowth and Cell Migration in Microexplant Cultures of the Cerebellum*

J. Gallo, N. Gallo‐Payet, L. Laflamme, 1999, The Journal of Biological Chemistry.

Proacrosin as a marker of meiotic and post-meiotic germ cell differentiation: quantitative assessment of human spermatogenesis with a monoclonal antibody.

F Ríus, J. Gallo, D. Escalier, 1994, Journal of reproduction and fertility.

Unexplained in-vitro fertilization failure: implication of acrosomes with a small reacting region, as revealed by a monoclonal antibody.

P. Jouannet, J. Gallo, D. Escalier, 1992, Human reproduction.

evaluation. Characterization of a monoclonal antibody to human proacrosin and its use in acrosomal status

J. Gallo, D. Escalier, P. Grellier, 2011 .

Characterization of a monoclonal antibody to human proacrosin and its use in acrosomal status evaluation.

J. Gallo, D. Escalier, P. Grellier, 1991, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Human acrosome biogenesis: immunodetection of proacrosin in primary spermatocytes and of its partitioning pattern during meiosis.

J. Gallo, D. Escalier, M. Albert, 1991, Development.

RNA Misprocessing in C9orf72-Linked Neurodegeneration

C. Shaw, J. Gallo, Youn-bok Lee, 2017, Front. Cell. Neurosci..

RNA Misprocessing in C9orf72-Linked Neurodegeneration

C. Shaw, J. Gallo, Youn-bok Lee, 2017, Front. Cell. Neurosci..

Aberrant RNA processing events in neurological disorders

K. Anthony, J. Gallo, Jean-Marc Gallo, 2010, Brain Research.

Quantitative analysis of tau isoform transcripts in sporadic tauopathies.

P. Lantos, T. Révész, D. Hanger, 2005, Brain research. Molecular brain research.

Biomedicine & Diseases: Review RNA and protein-dependent mechanisms in tauopathies: consequences for therapeutic strategies

W. Noble, J. Gallo, T. R. Martin, 2007 .

Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups

Peter M. G. Munro, L. da Cruz, P. Coffey, 2016, Cell stem cell.

Tau mis-splicing in the pathogenesis of neurodegenerative disorders

J. Gallo, S. A. Park, Sang Il Ahn, 2016, BMB reports.

Immunochemical Characterization of a Human Sperm Fibrous Sheath Protein, Its Developmental Expression Pattern, and Morphogenetic Relationships with Actin

J. Gallo, D. Escalier, J. Schrével, 1997, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling.

K. Aldape, H. DeLisser, J. Pittet, 1995, Journal of cell science.

Immunochemical and immunocytochemical studies of the crustacean vitellogenesis-inhibiting hormone (VIH).

J. Gallo, G. Martin, D. Soyez, 1987, General and comparative endocrinology.

Retention of hexanucleotide repeat-containing intron in C9orf72 mRNA: implications for the pathogenesis of ALS/FTD

C. Shaw, C. Troakes, S. Al-Sarraj, 2016, Acta Neuropathologica Communications.

Androgen Receptors Containing Expanded Polyglutamine Tracts Exhibit Progressive Toxicity when Stably Expressed in the Neuroblastoma Cell Line, SH-SY 5Y

J. Gallo, D. M. Avila, M. McPhaul, 2003, Experimental biology and medicine.

The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1

T. Webb, G. Michael, G. Blatch, 2009, Human molecular genetics.

Truncated forms of the androgen receptor are associated with polyglutamine expansion in X-linked spinal and bulbar muscular atrophy.

P. Leigh, J. Gallo, R. Butler, 1998, Human molecular genetics.

The effect of polyglutamine expansion in the human androgen receptor on its ability to suppress β-catenin-Tcf/Lef dependent transcription

P. Leigh, J. Gallo, R. Killick, 2004, Neuroscience Letters.

Hsp40 Molecules That Target to the Ubiquitin-proteasome System Decrease Inclusion Formation in Models of Polyglutamine Disease.

J. Uney, M. Cheetham, J. Gallo, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Subcellular sequestration of an antigenically unique beta-tubulin.

J. Gallo, E. Précigout, J. Schrével, 1988, Cell motility and the cytoskeleton.

Tau isoform expression and phosphorylation state during differentiation of cultured neuronal cells

J. Gallo, D. Davis, B. Anderton, 1995, FEBS letters.

A subpopulation of trypanosome microtubules recognized by a monoclonal antibody to tubulin.

J. Gallo, B. Anderton, 1983, The EMBO journal.

The Role of RNA and RNA Processing in Neurodegeneration

C. Thornton, J. Gallo, W. Schlaepfer, 2005, The Journal of Neuroscience.

Homologies between paraflagellar rod proteins from trypanosomes and euglenoids revealed by a monoclonal antibody.

J. Gallo, J. Schrével, 1985, European journal of cell biology.

Androgen‐induced up‐regulation of tubulin isoforms in neuroblastoma cells

P N Leigh, P. Leigh, J. Gallo, 2001, Journal of neurochemistry.

Mutually exclusive expression of βIII‐tubulin and vimentin in adrenal cortex carcinoma SW13 cells

J. Gallo, J. Robertson, R. Butler, 2000, FEBS letters.

The role of CELF proteins in neurological disorders

J. Gallo, C. Spickett, 2010, RNA biology.

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

T. Hortobágyi, C. Shaw, C. Troakes, 2018, Brain : a journal of neurology.

Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.

T. Hortobágyi, C. Shaw, C. Troakes, 2010, Brain : a journal of neurology.

Trans-splicing correction of tau isoform imbalance in a mouse model of tau mis-splicing

J. Gallo, M. Avale, T. Rodríguez-Martín, 2013, Human molecular genetics.

Modulation of PHF-like tau phosphorylation in cultured neurones and transfected cells

S. Lovestone, J. Woodgett, J. Brion, 1995, Neurobiology of Aging.

Modulation of Tau Isoforms Imbalance Precludes Tau Pathology and Cognitive Decline in a Mouse Model of Tauopathy.

J. Gallo, J. Belforte, M. Avale, 2018, Cell Reports.

Expression and phosphorylation of a three-repeat isoform of tau in transfected non-neuronal cells.

K. Kosik, D. Hanger, J. Gallo, 1992, The Biochemical journal.

Correction of tau mis-splicing caused by FTDP-17 MAPT mutations by spliceosome-mediated RNA trans-splicing

M. Garcia-Blanco, K. Anthony, S. Mansfield, 2009, Human molecular genetics.

Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: Implications for tauopathies

M. Garcia-Blanco, A. Grover, S. Mansfield, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Sites of phosphorylation in tau and factors affecting their regulation.

S. Lovestone, W. Blackstock, D. Hanger, 2000, Biochemical Society symposium.

Identification of novel in vitro PKA phosphorylation sites on the low and middle molecular mass neurofilament subunits by mass spectrometry.

W. Blackstock, J. Betts, J. Gallo, 1998, Biochemistry.

Transgenic mouse models of tauopathy in drug discovery.

W. Noble, D. Hanger, J. Gallo, 2010, CNS & neurological disorders drug targets.

Kennedy’s disease: a triplet repeat disorder or a motor neuron disease?

J. Gallo, 2001, Brain Research Bulletin.

Identification and Correct ion of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups Graphical

Peter R. T. Munro, P. Coffey, A. Moore, 2016 .

Ubiquitin, PGP 9.5 and dense body formation in trimethyltin intoxication: differential neuronal responses to chemically induced cell damage

J. Uney, J. Gallo, J. Cavanagh, 1992, Neuropathology and applied neurobiology.

Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration

C. Shaw, C. Troakes, S. Al-Sarraj, 2015, Acta neuropathologica communications.

Aggregation of Neurofilaments in NF‐L Transfected Neuronal Cells: Regeneration of the Filamentous Network by a Protein Kinase C Inhibitor

J. Gallo, J. Robertson, B. H. Anderton, 1996, Journal of neurochemistry.

Absence of disturbed axonal transport in spinal and bulbar muscular atrophy.

L. Greensmith, G. Schiavo, A. L. La Spada, 2011, Human molecular genetics.

Ligand-dependent aggregation of polyglutamine-expanded androgen receptor in neuronal cells

P. Leigh, P. Leigh, J. Gallo, 2002, Neuroreport.

Chapter 8 Spinobulbar muscular atrophy (Kennedy's disease).

P. Leigh, J. Gallo, 2007, Handbook of clinical neurology.

Spinobulbar muscular atrophy (Kennedy's disease)

J. Gallo, 2004 .

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.

L. Petrucelli, C. Shaw, C. Troakes, 2020, Human molecular genetics.

Expression, localization and tau exon 10 splicing activity of the brain RNA-binding protein TNRC4.

T. Cooper, K. Anthony, J. Gallo, 2007, Human molecular genetics.

Degradation properties of polyglutamine-expanded human androgen receptor in transfected cells

P. Leigh, J. Gallo, D. Cullen, 2004, Neuroscience Letters.

Tau isoforms imbalance impairs the axonal transport of the amyloid precursor protein in human neurons.

G. Forte, G. Stokin, T. Falzone, 2016, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Androgen-controlled specific gene expression in neuroblastoma cells

P. Leigh, S. Whatley, J. Gallo, 1995, Journal of the Neurological Sciences.

Effect of the Kennedy Mutation of the Androgen Receptor on Gene Expression in Neuroblastoma Cells

P. Leigh, J. Gallo, P. Yerramilli-Rao, 1996 .

Tau isoform expression and phosphorylation state during differentiation of cultured neuronal cells

J. Gallo, D. Davis, B. Anderton, 1995, FEBS letters.

Tau mRNA is present in axonal RNA granules and is associated with elongation factor 1A

K. Anthony, J. Gallo, Tony Malmqvist, 2014, Brain Research.

Modulation of Tau Isoforms Imbalance Precludes Tau Pathology and Cognitive Decline in a Mouse Model of Tauopathy.

J. Gallo, J. Belforte, M. Avale, 2018, Cell reports.

Protective effects of estrogens on polyglutamine-expanded human androgen receptor aggregation

P. Leigh, J. Gallo, R. Darrington, 2003, Neuroscience Letters.