D. Dexter

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Tumor heterogeneity and drug resistance.

D. Dexter, J. Leith, 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Intraneoplastic diversity.

D. Dexter, P. Calabresi, 1982, Biochimica et biophysica acta.

Chemotherapy of cell‐line‐derived human colon carcinomas in mice immunosuppressed with antithymocyte serum

D. Dexter, P. Calabresi, L. Tibbetts, 1977, Cancer.

Clinical and pharmacological implications of cancer cell differentiation and heterogeneity.

D. Dexter, G. Heppner, P. Calabresi, 1979, Biochemical pharmacology.

Activities of purine-metabolizing enzymes in human colon carcinoma cell lines and xenograft tumors.

L. Ghoda, D. Dexter, T. Savarese, 1981, Biochemical pharmacology.

Establishment and characterization of two human pancreatic cancer cell lines tumorigenic in athymic mice.

M. D. Turner, D. Dexter, P. Calabresi, 1982, Cancer research.

Cancer Cell Differentiation

D. Dexter, P. Calabresi, 1982 .

Alteration of the survival response of two human colon carcinoma subpopulations to x-irradiation by N,N-dimethylformamide.

D. Dexter, J. Leith, P. Calabresi, 1982, Cancer research.

Differential responses to x-irradiation of subpopulations of two heterogeneous human carcinomas in vitro.

J. Dewyngaert, D. Dexter, J. Leith, 1982, Cancer research.

Human tumor cell heterogeneity and metastasis.

D. Dexter, E. Spremulli, D L Dexter, 1983, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Thermal survival characteristics of cell subpopulations isolated from a heterogeneous human colon tumor.

J. Dewyngaert, D. Dexter, J. Leith, 1983, Cancer research.

Characterization of two metastatic subpopulations originating from a single human colon carcinoma.

D. Dexter, D. Gold, D. Shochat, 1983, Cancer research.

Biochemical pharmacology and toxicology of formycin alone and in combination with 2'-deoxycoformycin (pentostatin).

L. Ghoda, D. Dexter, P. Calabresi, 1983, Cancer treatment reports.

Enhancement by N-methylformamide of the effect of ionizing radiation on a human colon tumor xenografted in nude mice.

D. Dexter, J. Leith, E. Lee, 1984, Cancer research.

Intrinsic and extrinsic heterogeneity in the responses of parent and clonal human colon carcinoma xenografts to photon irradiation.

D. Dexter, J. Leith, E. Lee, 1984, Cancer research.

Preclinical antitumor activity of 6-hydroxymethylacylfulvene, a semisynthetic derivative of the mushroom toxin illudin S.

D. V. Von Hoff, G. Mangold, D. Dexter, 1997, Cancer research.

Intrinsic and Extrinsic Heterogeneity in the Responses of Parent and Clonal Human Colon Carcinoma Xenografts to Photon Irradiation 1

Eun Sun Lee, D. Dexter, J. Leith, 2006 .

Metastasis of a human pancreatic adenocarcinoma (RWP-1) in nude mice.

M. D. Turner, D. Dexter, S. Kajiji, 1982, British Journal of Cancer.

Mechanism of action of the novel anticancer agent 6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarbo xylic acid sodium salt (NSC 368390): inhibition of de novo pyrimidine nucleotide biosynthesis.

D. Dexter, S. Chen, R. L. Ruben, 1986, Cancer research.

GEM 231, a second-generation antisense agent complementary to protein kinase A RIalpha subunit, potentiates antitumor activity of irinotecan in human colon, pancreas, prostate and lung cancer xenografts.

Dong Yu, S. Agrawal, B. Hollister, 2002, International journal of oncology.

Disaggregation studies of xenograft solid tumors grown from pure or admixed clonal subpopulations from a heterogeneous human colon adenocarcinoma.

D. Dexter, J. Leith, E. Lee, 1985, Invasion & metastasis.

Effects of modulation of basic fibroblast growth factor on tumor growth in vivo.

A. Yayon, D. Dexter, J. L. Gross, 1993, Journal of the National Cancer Institute.

A model of human cancer metastasis: extensive spontaneous and artificial metastasis of a human pigmented melanoma and derived variant sublines in nude mice.

R. Kerbel, D. Dexter, M. S. Man, 1984, Journal of the National Cancer Institute.

The clinical pharmacology of 5-trifluoromethyl-2'-deoxyuridine.

W. Wolberg, C. Heidelberger, D. Dexter, 1972, Cancer research.

Establishment and Characterization of Two Human Pancreatic Cancer Cell Lines Tumorigenic in Athymic Mice 1

M. D. Turner, D. Dexter, P. Calabresi, 2006 .

Establishment and Characterization of Two Human Pancreatic Cancer Cell Lines Tumorigenic in Athymic Mice1

D. Dexter, P. Calabresi, G. Matook, 2006 .

Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate.

D. Dexter, D. Behrens, P. Kornblith, 1988, Cancer research.

Basic fibroblast growth factor: A potential autocrine regulator of human glioma cell growth

D. Dexter, R. Morrison, P. Kornblith, 1990, Journal of neuroscience research.

Chemotherapy of mammary carcinomas arising in ras transgenic mice

D. Dexter, S. Chen, M. Diamond, 1993, Investigational New Drugs.

Ultrastructural evidence of dimethylformamide‐induced differentiation of cultured human colon carcinoma cells increased expression of desmosomes

D. Dexter, N. Zamcheck, T. Christensen, 1985, Cancer.

N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells.

D. Dexter, P. Calabresi, J. Barbosa, 1979, Cancer research.

"COLO 357," a human pancreatic adenosquamous carcinoma: growth in artificial capillary culture and in nude mice.

M. D. Turner, D. Dexter, S. Kajiji, 1983, Cancer research.

Response of a human colon adenocarcinoma (DLD-1) to X irradiation and mitomycin C in vivo.

D. Dexter, J. Leith, P. Calabresi, 1983, International journal of radiation oncology, biology, physics.

Distribution of the novel anticancer drug candidate brequinar sodium (DuP 785, NSC 368390) into normal and tumor tissues of nude mice bearing human colon carcinoma xenografts

D. Dexter, D. Behrens, Huey-shin L. Shen, 1988, Cancer Chemotherapy and Pharmacology.

Polar solvent-induced changes in membrane lipid lateral diffusion in human colon cancer cells.

M. Dibner, D. Dexter, L. Koerner, 1985, Cancer research.

Synthesis and biological evaluation of 2-styrylquinazolin-4(3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization.

D. Dexter, E. Hamel, J. B. Jiang, 1990, Journal of medicinal chemistry.

Synthesis and biological evaluation of 2-styrylquinazolin-4(3H)-ones, a new class of antimitotic anticancer agents which inhibit tubulin polymerization.

D. Dexter, E. Hamel, J. B. Jiang, 1990, Journal of medicinal chemistry.

5'-deoxy-5'-methylthioadenosine phosphorylase--II. Role of the enzyme in the metabolism and antineoplastic action of adenine-substituted analogs of 5'-deoxy-5'-methylthioadenosine.

D. Dexter, T. Savarese, R. Parks, 1983, Biochemical pharmacology.

Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells.

L. Ghoda, D. Dexter, T. Savarese, 1983, Cancer research.

Heterogeneity of cancer cells from a single human colon carcinoma.

D. Dexter, P. Calabresi, E. Spremulli, 1981, The American journal of medicine.

Synthesis and biological evaluation of certain 4‐alkylamino and 4‐arylalkylamino derivatives of the imidazo[4,5‐d]pyridazine and v‐triazolo[4,5‐d]pyridazine ring systems

D. Dexter, P. Calabresi, R. P. Panzica, 1982 .

PRECLINICAL STUDIES WITH BREQUINAR SODIUM: A NOVEL ANTICANCER AGENT

D. Dexter, S. Chen, 1992 .

Preclinical Antitumor Activity and Pharmacokinetics of Methyl-2-Benzimidazolecarbamate (FB642)

D. V. Von Hoff, G. Mangold, D. Dexter, 2002, Investigational New Drugs.

Polar solvents: a novel class of antineoplastic agents.

D. Dexter, E. Spremulli, 1984, Journal of Clinical Oncology.

Selection of metastatic variants from heterogeneous tumor cell lines using the chicken chorioallantoic membrane and nude mouse.

D. Dexter, P. Calabresi, E. Spremulli, 1983, Cancer research.

A therapeutic monitoring assay for N-methylformamide in human serum and urine.

D. Dexter, P. Calabresi, G. Crabtree, 1983, Journal of analytical toxicology.

Nude mouse model of the melanosis syndrome.

R. Kuhn, D. Dexter, P. Calabresi, 1983, Journal of the National Cancer Institute.

Heterogeneity of tumor cells from a single mouse mammary tumor.

D. Dexter, G. Heppner, G H Heppner, 1978, Cancer research.

N,N-dimethylformamide and sodium butyrate modulation of the activities of purine-metabolizing enzymes in cultured human colon carcinoma cells.

L. Ghoda, D. Dexter, T. Savarese, 1981, Cancer research.

Maturation‐induction of tumor cells using a human colon carcinoma model

D. Dexter, J. Hager, 1980, Cancer.

N,N-Dimethylformamide-induced morphological differentiation and reduction of tumorigenicity in cultured mouse rhabdomyosarcoma cells.

D. Dexter, 1977, Cancer research.

Enhancement of the responses of human colon adenocarcinoma cells to X-irradiation and cis-platinum by N-methylformamide (NMF).

D. Dexter, J. Leith, A. Glicksman, 1985, International journal of radiation oncology, biology, physics.

Protection against hyperthermic cell killing of mouse mammary adenocarcinoma cells in vitro by N,N-dimethylformamide.

J. Dewyngaert, D. Dexter, J. Leith, 1981, Radiation research.

Modification of the response of mouse skin to x-irradiation by a polar solvent, N,N-dimethylformamide.

D. Dexter, J. Leith, P. Calabresi, 1982, International journal of radiation oncology, biology, physics.

Induction by butyrate of differentiated properties in cloned murine rhabdomyosarcoma cells.

J. R. Coleman, J. Lawrence, S. F. Konieczny, 1981, Differentiation; research in biological diversity.

Survival responses of cell subpopulations isolated from a heterogeneous human colon tumour after combinations of hyperthermia and X-irradiation.

J. Dewyngaert, D. Dexter, J. Leith, 1983, International journal of radiation biology and related studies in physics, chemistry, and medicine.

XB596, a promising bis‐naphthalimide anti‐cancer agent

S. P. Seitz, D. Dexter, C. Behrens, 1993, Anti-Cancer Drugs.

Activity of a novel 4-quinolinecarboxylic acid, NSC 368390 [6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarb oxylic acid sodium salt], against experimental tumors.

K. Paull, J. Plowman, D. Dexter, 1985, Cancer research.

Biosynthesis Pyrimidine Nucleotide de Novo ( NSC 368390 ) : Inhibition of-biphenyl-4-yl )-3-methyl-4-quinolinecarboxylic Acid Sodium Salt ′-fluoro-1 , 1 ′ 6-Fluoro-2-( 2 Mechanism of Action of the Novel Anticancer Agent

D. Dexter, R. L. Ruben, S. Chen, 2006 .

Biochemical pharmacology and toxicology of 8-azaadenosine alone and in combination with 2'-deoxycoformycin (pentostatin).

L. Ghoda, D. Dexter, P. Calabresi, 1982, Biochemical pharmacology.

Efficacy of DMP 840: a novel bis-naphthalimide cytotoxic agent with human solid tumor xenograft selectivity.

J. Miller, D. Dexter, C. Behrens, 1994, Cancer research.

Neoplastic subpopulations in carcinomas.

D. Dexter, 1981, Annals of Clinical and Laboratory Science.

Differential expression of tumor-associated antigens in human colon carcinomas xenografted into nude mice.

D. Goldenberg, D. Dexter, F. J. Primus, 1983, Journal of the National Cancer Institute.

Selective modification of the X ray survival response of two mouse mammary adenocarcinoma sublines by N,N-dimethylformamide.

J. Dewyngaert, D. Dexter, J. Leith, 1981, International journal of radiation oncology, biology, physics.

Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mammary tumor.

F. Miller, D. Dexter, G. Heppner, 1978, Cancer research.

Anti-tumor efficacy and biodistribution of intravenous polymeric micellar paclitaxel

Lawrence Mayer, Daniel Dexter, W. Hunter, 1997, Anti-cancer drugs.

An investigation of the antitumour activity and biodistribution of polymeric micellar paclitaxel

Daniel Dexter, W. L. Hunter, W. Hunter, 1997, Cancer Chemotherapy and Pharmacology.

Adaptation of Sinclair swine melanoma cells to long-term growth in vitro.

D. Dexter, E. Adelstein, R. Hook, 1979, Cancer research.

N,N-dimethylformamide-induced modulation of organ- and tumor-associated markers in cultured human colon carcinoma cells.

D. Dexter, D. Gold, J. Hager, 1980, Journal of the National Cancer Institute.

Structure-activity relationship of quinoline carboxylic acids. A new class of inhibitors of dihydroorotate dehydrogenase.

D. Dexter, R. Ardecky, S. Chen, 1990, Biochemical pharmacology.

Basic fibroblast growth factor-like activity and receptors are expressed in a human glioma cell line.

R. Alterman, D. Dexter, J. Moskal, 1990, Cancer research.

Expressed in a Human Glioma Cell Line Basic Fibroblast Growth Factor-like Activity and Receptors Are Updated Version

Joseph, R. Alterman, D. Dexter, 2006 .

Basic Fibroblast Growth Factor-like Activity and Receptors Are Expressed in a Human Glioma Cell Line 1

Joseph, R. Alterman, D. Dexter, 2006 .

Characterization of a defect in the pathway for converting 5'-deoxy-5'-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma.

L. Ghoda, D. Dexter, P. Trackman, 1984, The Journal of biological chemistry.

5’-methylthioadenosine phosphorylase as a chemotherapeutic target enzyme

D. Dexter, T. Savarese, P. Calabresi, 1982 .

Inhibition of the growth of human colon cancer xenografts by polar solvents.

D. Dexter, P. Calabresi, G. Matook, 1982, Cancer research.

Evidence of enhanced in vivo activity using tirapazamine with paclitaxel and paraplatin regimens against the MV-522 human lung cancer xenograft

D. V. Von Hoff, S. Hilsenbeck, G. Mangold, 1999, Cancer Chemotherapy and Pharmacology.

Evaluation of a novel bis-naphthalimide anticancer agent, DMP 840, against human xenografts derived from adult, juvenile, and pediatric cancers

P. Houghton, J. Houghton, D. Dexter, 2004, Cancer Chemotherapy and Pharmacology.

Sodium butyrate-induced alteration of growth properties and glycogen levels in cultured human colon carcinoma cells

D. Dexter, G. McKendall, R. Lev, 1984, The Histochemical Journal.

/ V , / V-Dimethylformamide and Sodium Butyrate Modulation of the Activities of Purine-metabolizing Enzymes in Cultured Human Colon Carcinoma Cells 1

L. Ghoda, D. Dexter, P. Calabresi, 2006 .

2'-Deoxycoformycin-induced hemolysis in the mouse.

D. Dexter, P. Calabresi, G. Crabtree, 1982, Journal of the National Cancer Institute.

Polar solvent modification of X ray induced potentially lethal damage in heterogeneous human colon tumor cells in vitro.

D. Dexter, J. Leith, A. Glicksman, 1984, International Journal of Radiation Oncology, Biology, Physics.

Heterogeneity in human colon cancer.

D. Dexter, 1983, Symposium on Fundamental Cancer Research.

Radiosensitivity of human colon carcinoma cells in vitro and in vivo. Abstr.

D. Dexter, J. Leith, P. Calabresi, 1980 .

Mammalian Tumor Cell Heterogeneity

D. Dexter, J. Leith, 1986 .

Fluorinated pyrimidines. 41. Syntheses of 5-trifluoromethyl-3'-deoxyuridine and 5-fluoro-3'-deoxyuridine.

S. Nesnow, C. Heidelberger, D. Dexter, 1972, Journal of medicinal chemistry.

Antitumor activity and toxicity of novel nitroheterocyclic phosphoramidates.

G. Mangold, D. Dexter, R. Baggs, 2001, Journal of medicinal chemistry.

Artificial capillary culture studies of human tumor cell growth, differentiation, and marker production.

D. Dexter, M. Wiemann, P. Calabresi, 1987, Journal of the National Cancer Institute.