G. Heppner

发表

Tumor heterogeneity: biological implications and therapeutic consequences

G. Heppner, B. Miller, Gloria H. Heppner, 2004, Cancer and Metastasis Reviews.

Natural killer‐cell activity under conditions reflective of tumor micro‐environment

G. Heppner, D. Loeffler, P. Juneau, 1991, International journal of cancer.

The cellular basis of tumor progression.

F. Miller, G. Heppner, F R Miller, 1998, International review of cytology.

Clinical and pharmacological implications of cancer cell differentiation and heterogeneity.

D. Dexter, G. Heppner, P. Calabresi, 1979, Biochemical pharmacology.

Effect of sequence of administration of methotrexate, leucovorin, and 5-fluorouracil on mammary tumor growth and survival in syngeneic C3H mice.

G. Heppner, P. Calabresi, 1977, Cancer research.

Tumor heterogeneity.

G. Heppner, 1984, Cancer research.

Dominance of a tumor subpopulation line in mixed heterogeneous mouse mammary tumors.

F. Miller, G. Heppner, B. Miller, 1988, Cancer research.

Analysis of tumour cell composition in tumours composed of paired mixtures of mammary tumour cell lines.

F. Miller, G. Heppner, B. Miller, 1987, British Journal of Cancer.

Relationships of prostaglandin E and natural killer sensitivity to metastatic potential in murine mammary adenocarcinomas.

G. Heppner, A. Fulton, 1985, Cancer research.

Mammary tumor heterogeneity.

F. Miller, G. Heppner, A. Fulton, 1983, Symposium on Fundamental Cancer Research.

Tumor-associated macrophages of mouse mammary tumors. II. Differential distribution of macrophages from metastatic and nonmetastatic tumors.

G. Heppner, A. Fulton, K. Mahoney, 1983, Journal of immunology.

Motility and tumoricidal activity of interleukin-2-stimulated lymphocytes.

G. Heppner, S. Ratner, 1988, Cancer research.

FACS Quantitation of Leucine Aminopeptidase and Acid Phosphatase on Tumor‐Associated Macrophages From Metastatic and Nonmetastatic Mouse Mammary Tumors

G. Heppner, B. Miller, K. Mahoney, 1985, Journal of leukocyte biology.

New directions in breast cancer research 1

G. Heppner, S. Wolman, E. Wolman, 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Racial differences in breast cancer patients.

J. Russo, G. Swanson, M. Brennan, 1985, Journal of the National Cancer Institute.

A 3-dimensional tumor growth inhibition assay for testing monoclonal antibody cytotoxicity

Wei-Zen Wei, G. Heppner, R. Massey, 2004, Cancer Immunology, Immunotherapy.

Immunoendocrine mechanisms in mammary tumor progression: Direct prolactin modulation of peripheral and preneoplastic hyperplastic-alveolar-nodule-infiltrating lymphocytes

G. Heppner, S. -. Jane Tsai, 1994, Cancer Immunology, Immunotherapy.

Transcriptional activation of functional endogenous estrogen receptor gene expression in MCF10AT cells: a model for early breast cancer.

F. Miller, G. Heppner, J. Christman, 1998, International journal of oncology.

FACS Analysis of Tumor‐Associated Macrophage Replication: Differences Between Metastatic and Nonmetastatic Murine Mammary Tumors

G. Heppner, K. Mahoney, Gloria H. Heppner, 1987, Journal of leukocyte biology.

Microcytotoxicity assay of immune responses to non-mammary tumor virus-induced, preneoplastic, and neoplastic mammary lesions in BALB/c mice.

D. Medina, G. Heppner, J. Kopp, 1976, Cancer research.

Immunological enhancement of breast cancer

G. Heppner, T. Stewart, T. Stewart, 1997, Parasitology.

Is there Evidence that Immunity Influences Tumor-Host Balance in Breast Cancer?

G. Heppner, 1973 .

In vitro studies on cell‐mediated immunity following surgery in mice sensitized to syngeneic mammary tumors

G. Heppner, G. H. Heppner, 2006, International journal of cancer.

NUCLEOSIDE ANALOGS IN THE TREATMENT OF NONNEOPLASTIC DISEASES *

P. Calabresi, G. Heppner, P. Calabresi, 1975, Annals of the New York Academy of Sciences.

Stimulation of hemolysin plaque-forming cells by idoxuridine.

G. Heppner, P. Calabresi, D. Griswold, 1975, Cancer research.

Analysis of distribution of tumor- and preneoplasia-infiltrating lymphocytes using simultaneous Hoechst 33342 labeling and immunophenotyping.

G. Heppner, D. Loeffler, P. Juneau, 1992, Cytometry.

Assessing tumor drug sensitivity by a new in vitro assay which preserves tumor heterogeneity and subpopulation interactions

F. Miller, G. Heppner, B. Miller, 1984, Journal of cellular physiology. Supplement.

Heterogeneity of expression and induction of mouse mammary tumor virus antigens in mouse mammary tumors.

G. Heppner, J. Hager, 1982, Cancer research.

Serum-mediated protection of neoplastic cells from inhibition by lymphocytes immune to their tumor-specific antigens.

G. Heppner, J. Yang, I. Hellstrom, 1969, Proceedings of the National Academy of Sciences of the United States of America.

Genetic heterogeneity in breast cancer.

G. Heppner, S. Wolman, 1992, Journal of the National Cancer Institute.

Cellular and Molecular Biology of Mammary Cancer

D. Medina, G. Heppner, W. Kidwell, 1987, Springer US.

Nontransgenic models of breast cancer.

F. Miller, G. Heppner, P. Shekhar, 2000, Breast cancer research : BCR.

Direct action of estrogen on sequence of progression of human preneoplastic breast disease.

D. Visscher, M. Shekhar, P. Nangia-Makker, 1998, The American journal of pathology.

Characterization of lymphocytic infiltrates in normal, preneoplastic, and neoplastic mouse mammary tissues.

W. Wei, G. Heppner, K. Mahoney, 1986, Cancer research.

Induction of antitumor immunity by interleukin-2 gene-transduced mouse mammary tumor cells versus transduced mammary stromal fibroblasts.

F. Miller, B. Gansbacher, G. Heppner, 1993, Journal of the National Cancer Institute.

Associated effects of bromocriptine on neoplastic progression of mouse mammary preneoplastic hyperplastic alveolar nodule line C4 and on hyperplastic alveolar nodule-infiltrating and splenic lymphocyte function.

G. Heppner, D. Loeffler, S. Tsai, 1992, Cancer research.

Specific killing of tumor cells In vitro in the presence of normal lymphoid cells and sera from hosts immune to the tumor antigens

G. Heppner, R. J. Brawn, S. Pollack, 1972, International journal of cancer.

Problems in the clinical use of the microcytotoxicity assay for measuring cell-mediated immunity to tumor cells.

G. Heppner, E. McDonough, P. Calabresi, 1975, Cancer research.

Detection of carcinoembryonic antigen in the media of cultures of carcinomatous cells of digestive-system origin.

L. E. Kopp, G. Heppner, P. Calabresi, 1972, Journal of the National Cancer Institute.

Malignant MCF10CA1 Cell Lines Derived from Premalignant Human Breast Epithelial MCF10AT Cells

Fred R. Miller, James Eliason, F. Miller, 2004, Breast Cancer Research and Treatment.

Tumor heterogeneity.

G. Heppner, 1984, Cancer research.

Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor: heterogeneity in phenotypic stability.

F. Miller, G. Heppner, B. Miller, 1983, Invasion & metastasis.

Evaluation of cell-mediated reactivity and serum blocking factors in melanoma patients on chemotherapy.

G. Heppner, P. Calabresi, F. Cummings, 1975, Medical and Pediatric Oncology.

Immune facilitation of breast cancer

G. Heppner, T. Stewart, 1999 .

Cell‐mediated and serum blocking reactivity to tumor antigens in patients with malignant melanoma

G. Heppner, E. McDonough, P. Calabresi, 1973, International journal of cancer.

Studies on serum‐mediated inhibition of cellular immunity to spontaneous mouse mammary tumors

G. Heppner, 1969, International journal of cancer.

In vitro demonstration of tumor‐specific antigens in spontaneous mammary tumors of mice

G. Heppner, G. Pierce, 1969, International journal of cancer.

Breast cancer immunology.

W. Wei, G. Heppner, W. Wei, 1996, Cancer treatment and research.

Characterization of a variant-producing tumor cell line from a heterogeneous strain BALB/cfC3H mouse mammary tumor.

A. Richardson, G. Heppner, S. Fligiel, 1981, Cancer research.

Growth interaction in vivo between tumor subpopulations derived from a single mouse mammary tumor.

F. Miller, J. Leith, G. Heppner, 1980, Cancer research.

Heterogeneity of tumor cells from a single mouse mammary tumor.

D. Dexter, G. Heppner, G H Heppner, 1978, Cancer research.

Cellular interactions in metastasis

F. Miller, G. Heppner, 1990, Cancer and Metastasis Reviews.

Interaction of Mammary Tumor Subpopulations

F. Miller, G. Heppner, 1987 .

A dilute agar colony inhibition (CI) test for studying cell‐mediated immune responses against tumor cells

G. Heppner, J. Kopp, 1971, International journal of cancer.

Influence of serial transplantation on the immunological-clinical correlates of BALB/cfC3H mouse mammary tumors.

F. Miller, G. Heppner, J. Hager, 1978, Cancer research.

Differential sensitivity of metastatic versus nonmetastatic mammary tumor cells to macrophage-mediated cytostasis.

G. Heppner, A. Fulton, K. Yamashina, 1985, Journal of the National Cancer Institute.

Neonatal thymectomy and mouse mammary tumorigenesis, p. 503-524. In l. Severi, [ed.], Immunity and tolerance in oncogenesis (iv perugia quadrennial internat. Conf. Cancer 1969). Published by the division of cancer research p.o.b. 327 06100 Perugia

G. Heppner, 1970 .

Studies on the role of the thymus in viral tumorigenesis. I. Effect of thymectomy on induction of hyperplastic alveolar nodules and mammary tumors in BALB-cfC3H mice.

D. W. Weiss, G. Heppner, P. C. Wood, 1968, Israel journal of medical sciences.

Cell-mediated “Immunostimulation” induced by Mammary Tumour Virus-free Balb/c Mammary Tumours

D. Medina, G. Heppner, 1973, Nature.

Immunology: breast cancer.

G. Heppner, 1976, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Epithelial characteristics of five subpopulations of a heterogeneous strain BALB/cfC3H mouse mammary tumor.

J. Russo, R. Ceriani, G. Heppner, 1981, Cancer research.

Cellular Heterogeneity of Human Tumors

Y. Rustum, G. Heppner, H. Slocum, 1985 .

Inflammatory infiltrates of experimental mammary cancers.

W. Wei, G. Heppner, W Z Wei, 1986, Biochimica et biophysica acta.

Tumor cell societies.

G. Heppner, 1989, Journal of the National Cancer Institute.

Suppression by cytosine arabinoside of serum-blocking factors of cell-mediated immunity to syngeneic transplants of mouse mammary tumors.

G. Heppner, P. Calabresi, 1972, Journal of the National Cancer Institute.

Selective suppression of humoral and cellular immunity with cytosine arabinoside.

G. Heppner, P. Calabresi, D. Griswold, 1972, Cancer research.

Correction of a murine mammary tumor virus-associated immunological depression by selective immunosuppression with cytosine arabinoside.

G. Heppner, D. Griswold, J. Manning, 1975, Cancer Research.

Role of murine tumor models in cancer treatment research.

P. Houghton, B. Fisher, J. Houghton, 1986, Cancer research.

Stimulatory effects of 5-lodo-2'-deoxyuridine on number and function of splenic B- and T-cells and of macrophages in C3HeB/FeJ mice.

G. Heppner, S. Leitman, P. Calabresi, 1976, Cancer research.

Selective immunosuppression by drugs in balanced immune responses.

G. Heppner, P. Calabresi, E. Poplin, 1974, Federation proceedings.

Selective suppression of humoral immunity by antineoplastic drugs.

G. Heppner, P. Calabresi, 1976, Annual review of pharmacology and toxicology.

Alteration of immunocompetence by mammary tumor virus.

G. Heppner, P. Calabresi, D. Griswold, 1973, Journal of the National Cancer Institute.

Tamoxifen Suppresses Histologic Progression to Atypia and DCIS in MCFIOAT Xenografts, a Model of Early Human Breast Cancer

D. Visscher, G. Heppner, P. Shekhar, 2004, Breast Cancer Research and Treatment.

MCF‐10AT: A Model for Human Breast Cancer Development

G. Heppner, S. Wolman, 1999, The breast journal.

Chromosomal markers of immortalization in human breast epithelium

G. Heppner, H. Soule, S. Wolman, 1994, Genes, chromosomes & cancer.

MCF10AT: a model for the evolution of cancer from proliferative breast disease.

F. Miller, G. Heppner, L. Tait, 1996, The American journal of pathology.

Xenograft model of progressive human proliferative breast disease.

F. Miller, G. Heppner, H. Soule, 1993, Journal of the National Cancer Institute.

Preferential growth of mammary tumors in intact mammary fatpads.

D. Medina, F. Miller, G. Heppner, 1981, Cancer research.

Comedo-Ductal carcinoma in situ: A paradoxical role for programmed cell death

D. Visscher, Gen Sheng Wu, M. Shekhar, 2008, Cancer biology & therapy.

Cancer cell societies and tumor progression

G. Heppner, Gloria H. Heppner, 1993, Stem cells.

In situ lymphoid cells of mouse mammary tumors. I. Development and evaluation of a method for the separation of lymphoid cells from mouse mammary tumors.

G. Heppner, B. Blazar, 1978, Journal of immunology.

The MCF10 family of spontaneously immortalized human breast epithelial cell lines: models of neoplastic progression.

F. Miller, G. Heppner, H. Soule, 1993, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

Significance of three-dimensional growth patterns of mammary tissues in collagen gels

F. Miller, G. Heppner, E. M. Lawler, 1983, In Vitro.

Tumor subpopulation interactions in neoplasms.

F. Miller, G. Heppner, B. Miller, 1983, Biochimica et biophysica acta.

Interactions between tumor subpopulations affecting their sensitivity to the antineoplastic agents cyclophosphamide and methotrexate.

F. Miller, G. Heppner, B. Miller, 1981, Cancer research.

Immunologic heterogeneity of tumor cell subpopulations from a single mouse mammary tumor.

F. Miller, G. Heppner, 1979, Journal of the National Cancer Institute.

Heterogeneity in drug sensitivity among tumor cell subpopulations of a single mammary tumor.

F. Miller, D. Dexter, G. Heppner, 1978, Cancer research.

Host microenvironment in breast cancer development: Extracellular matrix–stromal cell contribution to neoplastic phenotype of epithelial cells in the breast

M. Shekhar, G. Heppner, R. Pauley, 2003, Breast Cancer Research.

Alterations of immune reactivity by haloperidol and delta-9-tetrahydrocannabinol.

G. Heppner, J. A. Levy, 1981, Journal of immunopharmacology.

Analysis oftumourcell composition intumours composed ofpaired mixtures ofmammary tumourcell lines

F. Miller, G. Heppner, B. Miller, 1987 .

Reactive oxygen-mediated damage to murine mammary tumor cells.

G. Heppner, A. Fulton, L. A. Paul, 1989, Mutation research.

Therapeutic perturbation of the tumor ecosystem in reconstructed heterogeneous mouse mammary tumors.

F. Miller, G. Heppner, B. Miller, 1989, Cancer research.

Macrophage-mediated induction of drug-resistant variants in a mouse mammary tumor cell line.

G. Heppner, B. Miller, K. Yamashina, 1986, Cancer research.

Correlation of frequency of induced mutation and metastatic potential in tumor cell lines from a single mouse mammary tumor.

G. Heppner, K. Yamashina, 1985, Cancer research.

Rates of development of methotrexate resistance in heterogeneous mouse mammary tumor cell cultures.

L. Matherly, G. Heppner, B. Miller, 1996, Journal of experimental therapeutics & oncology.

Tumor subpopulation interactions affecting melphalan sensitivity in palpable mouse mammary tumors.

T. Machemer, G. Heppner, B. Miller, 1991, Cancer research.

Macrophage-mediated induction of DNA strand breaks in target tumor cells.

G. Heppner, A. Fulton, L. A. Paul, 1989, Cancer research.

Mutagenic activity of tumor-associated macrophages in Salmonella typhimurium strains TA98 and TA 100.

G. Heppner, A. Fulton, S. Loveless, 1984, Cancer research.

Characterization of tumor-associated lymphocytes in a series of mouse mammary tumor lines with differing biological properties

F. Miller, G. Heppner, A. Rios, 2004, Cancer Immunology, Immunotherapy.

Problems Posed for Cancer Treatment by Tumor Cell Heterogeneity

G. Heppner, 1986 .

Factors affecting growth and drug sensitivity of mouse mammary tumor lines in collagen gel cultures.

F. Miller, G. Heppner, B. Miller, 1985, Cancer research.

CHAPTER 1 – ROLE OF CELLULAR HETEROGENEITY IN TUMOR BEHAVIOR

F. Miller, G. Heppner, A. Fulton, 1985 .

Bioactivities and the effect of dilution on various milk‐borne murine mammary tumor viruses

A. Vaidya, G. Heppner, D. Moore, 1979, International journal of cancer.

Tumor antigens: Biological activity of components of soluble antigens of MTV-induced mammary tumors

G. Heppner, J. Bekesi, C. Laing, 2004, Cancer Immunology, Immunotherapy.

Correlation of natural killer activity with tumorigenesis of a preneoplastic mouse mammary lesion.

W. Wei, J. Winkelhake, G. Heppner, 1989, Cancer research.

Natural killer activity of lymphocytic infiltrates in mouse mammary lesions.

W. Wei, G. Heppner, W. Wei, 1987, British Journal of Cancer.

Melphalan sensitivity as a function of progressive metastatic growth in two subpopulations of a mouse mammary tumour.

F. Miller, T. Machemer, G. Heppner, 1993, British Journal of Cancer.

Assessment of syngeneic cell-mediated immunity to mouse mammary tumors by three different assays

F. Miller, G. Heppner, 1979, Cancer Immunology, Immunotherapy.

Tumor immunity in the mammary gland

F. Miller, G. Heppner, 1982, Cancer Immunology, Immunotherapy.

In situ lymphoid cells of mouse mammary tumors. II. The characterization of lymphoid cells separated from mouse mammary tumors.

G. Heppner, B. Blazer, 1978, Journal of immunology.

In situ lymphoid cells of mouse mammary tumors. III. In vitro stimulation of tumor cell survival by lymphoid cells separated from mammary tumors.

F. Miller, G. Heppner, B. Blazar, 1978, Journal of immunology.

Relationship of natural killer cytotoxicity to clinical and biochemical parameters of primary human breast cancer

J. Russo, M. Brennan, G. Heppner, 2005, Breast Cancer Research and Treatment.

Tumoricidal macrophages isolated from liver granulomas of Schistosoma mansoni-infected mice.

G. Heppner, D. Boros, S. Loveless, 1982, Journal of immunology.

Motility of murine lymphocytes during transit through cell cycle. Analysis by a new in vitro assay.

R. Jasti, G. Heppner, S. Ratner, 1988, Journal of immunology.

Mechanisms of lymphocyte traffic in neoplasia.

G. Heppner, S. Ratner, Heppner Gh, 1986, Anticancer research.

T cell locomotion in the tumor microenvironment. I. A collagen-matrix assay.

G. Heppner, S. Ratner, 1985, Journal of Immunology.

Xenograft Models of Human Breast Cancer Lines and of the MCF10AT Model of Human Premalignant, Proliferative Breast Disease

F. Miller, G. Heppner, 2000 .

Differential radiobiological characteristics of heterogeneous tumor cell subpopulations from a single tumor

J. Leith, G. Heppner, A. Glicksman, 1979 .

Activity of lymphoid cells separated from mammary tumors in blastogenesis and Winn assays.

F. Miller, G. Heppner, C. Laing, 1980, Journal of the National Cancer Institute.

High Susceptibility of Strain A Mice to Endotoxin and Endotoxin-Red Blood Cell Mixtures

D. W. Weiss, G. Heppner, 1965, Journal of bacteriology.

Immunosuppression by marihuana and its cannabinoid constituents.

G. Heppner, J. A. Levy, 1980, Journal of immunopharmacology.

Alterations in murine delayed type hypersensitivity responses by delta-8-THC and cannabinol.

G. Heppner, J. A. Levy, 1978, Journal of immunopharmacology.

Tumor-associated macrophages of mouse mammary tumors. I. Differential cytotoxicity of macrophages from metastatic and nonmetastatic tumors.

G. Heppner, S. Loveless, 1983, Journal of immunology.

Host inflammatory cells and generation of tumor cell diversity.

G. Heppner, A. Fulton, L. Dorcey, 1988, Advances in experimental medicine and biology.

FACS Analysis of Tumor-Associated Macrophage Replication:

G. Heppner, K. Mahoney, 1987 .

ALTERATIONS IN MUFXNE DFLAYED TYPE HYPI2FSUSITMTY RESPONSES BY DELTA-8-THC AND cA"ABIKIL1

G. Heppner, J. A. Levy, 1978 .

Author Index to Volume 228, April-June 1985

F. Bloom, K. Arrow, P. Anderson, 1985, Science.

Therapeutic implications of tumor heterogeneity.

G. Heppner, B. Miller, 1989, Seminars in oncology.

Tumor heterogeneity is fundamental to the tumor ecosystem.

M. Shekhar, G. Heppner, 2014, Oncology.

Dynamic stromal‐epithelial interactions during progression of MCF10DCIS.com xenografts

H. Heng, J. Rak, F. Miller, 2007, International journal of cancer.

Host‐Mediated Induction of Tumor Heterogeneity a

G. Heppner, A. Fulton, Y. Chong, 1989, Annals of the New York Academy of Sciences.

Tumor heterogeneity: biological implications and therapeutic consequences

G. Heppner, B. Miller, 2004, Cancer and Metastasis Reviews.

Preferential growth of mammary tumors in intact mammary fatpads.

D. Medina, F. Miller, G. Heppner, 1981, Cancer research.

Tumor infiltrating lymphocytes of spontaneous versus transplanted mouse mammary tumors

Wei-Zen Wei, G. Heppner, 2004, Cancer Immunology, Immunotherapy.

Cell-to-cell interaction in regulating diversity of neoplasms.

G. Heppner, G H Heppner, 1991, Seminars in cancer biology.