Xin-yang Li

发表

Study of Imidazolium Salt Derivatives as PIK3CA Inhibitors Using a Comprehensive in Silico Method

Ming-yang Wang, Jing-wei Liang, Xin-yang Li, 2018, International journal of molecular sciences.

Design, synthesis and biological evaluation of erythrina derivatives bearing a 1,2,3-triazole moiety as PARP-1 inhibitors.

X. Qian, Xin-yang Li, Fan-hao Meng, 2020, Bioorganic chemistry.

Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis.

X. Qian, Xin-yang Li, Fan-hao Meng, 2021, Bioorganic chemistry.

Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity

Xin-yang Li, Fan-hao Meng, Ting-jian Zhang, 2019, Cell Death & Disease.

Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.

Jing-wei Liang, Xin-yang Li, Fan-hao Meng, 2019, Bioorganic chemistry.

2-((1-Phenyl-1H-1,2,3-triazol-4-yl)methyl)-2-azabicyclo[3.2.1]octan-3-one derivatives: Simplification and modification of aconitine scaffold for the discovery of novel anticancer agents.

X. Qian, Jing-wei Liang, Xin-yang Li, 2020, European journal of medicinal chemistry.

Structural classification of MELK inhibitors and prospects for the treatment of tumor resistance: A review.

Xin-yang Li, Gang Dong, L. Ren, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Design, synthesis, and in vitro and in vivo anti-angiogenesis study of a novel vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor based on 1,2,3-triazole scaffold.

X. Qian, Xin-yang Li, Fan-hao Meng, 2020, European journal of medicinal chemistry.

Determination of Structural Requirements of N-Substituted Tetrahydro-β-Carboline Imidazolium Salt Derivatives Using in Silico Approaches for Designing MEK-1 Inhibitors

Ming-yang Wang, Jing-wei Liang, Xin-yang Li, 2017, Molecules.

Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation.

X. Qian, Xin-yang Li, Fan-hao Meng, 2021, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.

Jing-wei Liang, Xin-yang Li, Fan-hao Meng, 2018, European journal of medicinal chemistry.

Novel 4,5-dihydrospiro[benzo[c]azepine-1,1'-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation.

Xin-yang Li, Fan-hao Meng, Ting-jian Zhang, 2021, Bioorganic chemistry.

Design, synthesis and anticancer activities evaluation of novel 5H-dibenzo[b,e]azepine-6,11-dione derivatives containing 1,3,4-oxadiazole units.

Jing-wei Liang, Xin-yang Li, Fan-hao Meng, 2018, Bioorganic & medicinal chemistry letters.

Development of a novel thymidylate synthase (TS) inhibitor capable of up-regulating P53 expression and inhibiting angiogenesis in NSCLC

X. Qian, Xin-yang Li, Fan-hao Meng, 2020, Journal of advanced research.

Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.

Xin-yang Li, Fan-hao Meng, De-pu Wang, 2019, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel (E)-N-phenyl-4-(pyridine-acylhydrazone) benzamide derivatives as potential antitumor agents for the treatment of multiple myeloma (MM).

X. Qian, Xin-yang Li, Fan-hao Meng, 2020, Bioorganic chemistry.

Fragment-Based Structural Optimization of a Natural Product Itampolin A as a p38α Inhibitor for Lung Cancer

Ming-yang Wang, Jing-wei Liang, Xin-yang Li, 2019, Marine drugs.

Synthesis and evaluation of novel HER-2 inhibitors to exert anti-breast cancer ability through epithelial-mesenchymal transition (EMT) pathway.

X. Qian, Xin-yang Li, Fan-hao Meng, 2022, European journal of medicinal chemistry.

Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity

Xin-yang Li, Fan-hao Meng, Ting-jian Zhang, 2019, Cell Death & Disease.

Discovery of novel thymidylate synthase (TS) inhibitors that influence cancer angiogenesis and metabolic reprogramming in NSCLC cells.

Xin-yang Li, Fan-hao Meng, W. Xue, 2023, European journal of medicinal chemistry.