S. Akiyama

发表

Fibronectin and integrins in invasion and metastasis

Kenneth M. Yamada, K. Olden, S. Akiyama, 1995, Cancer and Metastasis Reviews.

Identification of two distinct regions of the type III connecting segment of human plasma fibronectin that promote cell type-specific adhesion.

M. Humphries, K. Olden, K. Yamada, 1987, The Journal of biological chemistry.

Latex beads as probes of cell surface-extracellular matrix interactions during chondrogenesis: evidence for a role for amino-terminal heparin-binding domain of fibronectin.

S A Newman, S. Newman, S. Akiyama, 1989, Developmental biology.

Integrin function: molecular hierarchies of cytoskeletal and signaling molecules

K. Yamada, J. Gutkind, S. Akiyama, 1995, The Journal of cell biology.

The interaction of fibronectin fragments with fibroblastic cells.

K. Yamada, S. Akiyama, T. Hasegawa, 1985, The Journal of biological chemistry.

Vinexin Forms a Signaling Complex with Sos and Modulates Epidermal Growth Factor-induced c-Jun N-terminal Kinase/Stress-activated Protein Kinase Activities*

S. Aota, K. Yamada, A. Suwa, 1999, The Journal of Biological Chemistry.

Regulation of cell-substrate adhesion by proteoglycans immobilized on extracellular substrates.

M. Yamagata, K. Yamada, S. Akiyama, 1989, The Journal of biological chemistry.

Monoclonal antibody characterization of two distant sites required for function of the central cell-binding domain of fibronectin in cell adhesion, cell migration, and matrix assembly

S. Aota, K. Olden, K. Yamada, 1991, The Journal of cell biology.

Function and receptor specificity of a minimal 20 kilodalton cell adhesive fragment of fibronectin.

S. Aota, K. Yamada, S. Akiyama, 1995, Cell adhesion and communication.

Transforming growth factor beta stimulates the expression of fibronectin and of both subunits of the human fibronectin receptor by cultured human lung fibroblasts.

W. T. Chen, J. McQuillan, K. Yamada, 1988, The Journal of biological chemistry.

Expression and ligand binding of α2β1 integrin on breast carcinoma cells

R. Dickson, S. Akiyama, V. Woods, 1995, Clinical & Experimental Metastasis.

Localization of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas.

H. Gralnick, H. Larjava, J. Uitto, 1989, The Journal of clinical investigation.

Integrin Clustering and Stimulates Cell Migration

S. Akiyama, M. Pierce, Intaek Lee, 2002 .

A two‐domain mechanism for group A streptococcal adherence through protein F to the extracellular matrix.

K. Yamada, E. Hanski, S. Akiyama, 1996, The EMBO journal.

BCL2 inhibits Cell Adhesion, Spreading, and Motility by Enhancing Actin Polymerization

Jennifer Y. Zhang, J. French, Hengning Ke, 2010, Cell Research.

Functional analysis of cell adhesion: quantitation of cell-matrix attachment.

S. Akiyama, S. K. Akiyama, 2002, Methods in cell biology.

The structure of fibronectin and its role in cellular adhesion.

K. Yamada, S. Akiyama, M. Hayashi, 1981, Journal of supramolecular structure and cellular biochemistry.

Basic fibroblast growth factor release by human coronary artery endothelial cells is enhanced by matrix proteins, 17beta-estradiol, and a PKC signaling pathway.

H. Schnaper, S. Akiyama, M. L. Albuquerque, 1998, Experimental cell research.

Collagen, and Laminin in Human Skin Variable Expression in Basal and Squamous Cell Carcinomas

Kenneth M. Yamada, H. Gralnick, H. Larjava, 1989 .

Inhibition of experimental metastasis of human breast-carcinoma cells in athymic nude-mice by anti-alpha(5)beta(1) fibronectin receptor integrin antibodies.

H. Gralnick, K. Olden, K. Yamada, 1995, International journal of oncology.

Human neutrophil adherence to laminin in vitro. Evidence for a distinct neutrophil integrin receptor for laminin

C. Damsky, G. Zimmerman, S. Akiyama, 1990, The Journal of experimental medicine.

Introduction: Preparation of adhesive surfaces and proteins

S. Akiyama, R. Klebe, 1994 .

Activation of CD4 cells by fibronectin and anti-CD3 antibody. A synergistic effect mediated by the VLA-5 fibronectin receptor complex

C. Morimoto, K. Yamada, S. Akiyama, 1989, The Journal of experimental medicine.

A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells.

W. T. Chen, T. Kelly, S. Akiyama, 1994, Cancer research.

Fibroblast-mediated collagen gel contraction does not require fibronectin-alpha 5 beta 1 integrin interaction.

S. Akiyama, J. Tomasek, 1992, The Anatomical record.

Mechanisms of fibronectin and integrin function during cell adhesion and migration.

S. Aota, K. Yamada, S. Akiyama, 1992, Cold Spring Harbor symposia on quantitative biology.

STRUCTURE AND FUNCTION OF FIBRONECTIN

Kenneth M. Yamada, S. Akiyama, M. Hayashi, 1982 .

Regulation of Integrin α5β1-Fibronectin Interactions by Divalent Cations

M. Humphries, A. Mould, S. Akiyama, 1995, The Journal of Biological Chemistry.

Structural and functional comparisons of chicken and human cellular fibronectins.

B. Bernard, K. Olden, K. Yamada, 1984, The Journal of biological chemistry.

Transmembrane signal transduction by integrin cytoplasmic domains expressed in single-subunit chimeras.

K. Yamada, S. Akiyama, S. Yamada, 1994, The Journal of biological chemistry.

Matrix-driven translocation: dependence on interaction of amino-terminal domain of fibronectin with heparin-like surface components of cells or particles.

S. Newman, S. Akiyama, D. Frenz, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Bioadhesion and cell behavior

S. Akiyama, S. LaFlamme, S. K. Akiyama, 1994 .

Biosynthesis and acquisition of biological activity of the fibronectin receptor.

K. Yamada, S. Akiyama, Kenneth M. Yamada, 1987, The Journal of biological chemistry.

An assessment of the efficacy of anti-integrin alpha subunit monoclonal antibody production using affinity purified beta 1-integrin dimers as immunogen.

M. Humphries, A. Mould, K. Yamada, 1991, Biochemical Society transactions.

The carboxy-terminal extension of the collagen binding domain of fibronectin mediates interaction with a 165 kDa membrane protein involved in odontoblast differentiation.

S. Akiyama, H. Lesot, J. Ruch, 1992, Differentiation; research in biological diversity.

A mechanism for regulation of melanoma invasion. Ligation of alpha6beta1 integrin by laminin G peptides.

W. T. Chen, Y. Yamada, M. Nomizu, 1996, The Journal of biological chemistry.

Comparisons of evolutionarily distinct fibronectins: Evidence for the origin of plasma and fibroblast cellular fibronectins from a single gene

K. Yamada, S. Akiyama, S. K. Akiyama, 1985, Journal of cellular biochemistry.

The Interactions of Cells with Extracellular Matrix Components

Kenneth M. Yamada, S. Akiyama, K. Yamada, 1984 .

Purification of Vitronectin

S. Akiyama, S. K. Akiyama, 1999, Current protocols in cell biology.

Anti‐integrin antibodies induce type IV collagenase expression in keratinocytes

H. Birkedal‐Hansen, H. Larjava, T. Salo, 1993, Journal of cellular physiology.

Recent advances in research on fibronectin and other cell attachment proteins

M. Humphries, K. Olden, K. Yamada, 1985, Journal of cellular biochemistry.

Altered glycosylation and cell surface expression of beta 1 integrin receptors during keratinocyte activation.

K. Yamada, F. Grinnell, S. Akiyama, 1992, Journal of cell science.

Swainsonine stimulation of the proliferation and colony forming activity of murine bone marrow.

K. Olden, S. Akiyama, K. Grzegorzewski, 1991, Cancer communications.

Aberrant N-Glycosylation of β1 Integrin Causes Reduced α5β1 Integrin Clustering and Stimulates Cell Migration

S. Akiyama, M. Pierce, Intaek Lee, 2002 .

Cis-polyunsaturated fatty acids stimulate beta1 integrin-mediated adhesion of human breast carcinoma cells to type IV collagen by activating protein kinases C-epsilon and -mu.

K. Olden, F. Wolber, S. Akiyama, 2001, Cancer research.

Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

M. Humphries, A. Mould, S. Akiyama, 1995, The Journal of biological chemistry.

A Novel Protease-docking Function of Integrin at Invadopodia*

S. Akiyama, S. Mueller, Q. Sang, 1999, The Journal of Biological Chemistry.

A Mechanism for Regulation of Melanoma Invasion

Yoshihiko Yamada, M. Nomizu, S. Akiyama, 1996, The Journal of Biological Chemistry.

Inhibition of Binding of Fibronectin to Matrix Assembly Sites by Anti-Integrin Antibodies

Kenneth M. Yamada, S. Akiyama, F. J. Fogerty, 2002 .

Inhibition of binding of fibronectin to matrix assembly sites by anti- integrin (alpha 5 beta 1) antibodies

K. Yamada, D. Mosher, S. Akiyama, 1990, The Journal of cell biology.

Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration.

W. T. Chen, H. Gralnick, K. Yamada, 1990, Cancer research.

Distinct regions of human fibronectin are essential for fibril assembly in an in vivo developing system

J. Thiery, V. Koteliansky, K. Yamada, 1992, Developmental dynamics : an official publication of the American Association of Anatomists.

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization

W. T. Chen, K. Yamada, S. Akiyama, 1989, The Journal of cell biology.

Fibronectin in evolution: presence in invertebrates and isolation from Microciona prolifera.

S. Akiyama, M. D. Johnson, S. K. Akiyama, 1983, Comparative biochemistry and physiology. B, Comparative biochemistry.

Fibroblast‐mediated collagen gel contraction does not require fibronectin‐α5β1 integrin interaction

S. Akiyama, J. Tomasek, S. K. Akiyama, 1992 .

Cell surface receptors for extracellular matrix components.

K. Yamada, S. Akiyama, K. Nagata, 1990, Biochimica et biophysica acta.

Analysis of the role of glycosylation of the human fibronectin receptor.

K. Yamada, S. Akiyama, S. Yamada, 1989, The Journal of biological chemistry.

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion

M. Humphries, K. Olden, K. Yamada, 1986, The Journal of cell biology.

Purification of Fibronectin

S. Akiyama, S. K. Akiyama, 2013, Current protocols in cell biology.

Purification of Fibronectin

S. Akiyama, S. K. Akiyama, 1999, Current protocols in cell biology.

Regulation of fibronectin receptor distribution [published erratum appears in J Cell Biol 1992 Jul;118(2):491]

Kenneth M. Yamada, S. Akiyama, S. LaFlamme, 1992, The Journal of cell biology.

Regulation of Fibronectin Receptor Distribution

K. Yamada, S. Akiyama, S. LaFlamme, 2002 .

Neurite extension of chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type III connecting segment

M. Humphries, K. Olden, K. Yamada, 1988, The Journal of cell biology.

Characterization of a 140-kD avian cell surface antigen as a fibronectin-binding molecule

K. Yamada, S. Akiyama, S. Yamada, 1986, The Journal of cell biology.

Fibronectin structure and function, and its interactions with glycosaminoglycans.

K. Yamada, S. Akiyama, M. Hayashi, 1981, Biochemical Society transactions.

Novel function for beta 1 integrins in keratinocyte cell-cell interactions

H. Gralnick, H. Larjava, J. Uitto, 1990, The Journal of cell biology.

Fibronectin in disease.

K. Yamada, S. Akiyama, 1983, Monographs in pathology.

The inhibitory anti-beta1 integrin monoclonal antibody 13 recognizes an epitope that is attenuated by ligand occupancy. Evidence for allosteric inhibition of integrin function.

M. Humphries, A. Mould, S. Akiyama, 1996, The Journal of biological chemistry.

The interaction of plasma fibronectin with fibroblastic cells in suspension.

K. Yamada, S. Akiyama, S. K. Akiyama, 1985, The Journal of biological chemistry.

Solution structure and dynamics of linked cell attachment modules of mouse fibronectin containing the RGD and synergy regions: comparison with the human fibronectin crystal structure.

S. Aota, D. Torchia, R. Pastor, 1998, Journal of molecular biology.

Integrins in cell adhesion and signaling.

S. Akiyama, S. K. Akiyama, 1996, Human cell.

Identification of a novel anti‐integrin monoclonal antibody that recognises a ligand‐induced binding site epitope on the β1 subunit

M. Humphries, A. Mould, A. Garratt, 1995, FEBS letters.

Introduction: adhesion molecules in cancer. Part I.

K. Yamada, S. Akiyama, S. K. Akiyama, 1993, Seminars in cancer biology.

Positive regulation of cell-cell and cell-substrate adhesion by protein kinase A.

S. Akiyama, J. Whittard, S. K. Akiyama, 2001, Journal of cell science.

P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin.

John D. Roberts, S. Akiyama, M. D. George, 2006, Experimental cell research.

Functional interactions of fibronectin and TNF alpha: a paradigm of physiological linkage between cytokines and extracellular matrix moieties.

A. Miller, K. Yamada, S. Akiyama, 1994, Cell adhesion and communication.

Altered processing of integrin receptors during keratinocyte activation.

H. Gralnick, K. Yamada, F. Grinnell, 1991, Experimental cell research.

CYLD inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways

Jennifer Y. Zhang, C. Augustine, D. Tyler, 2012, The Journal of investigative dermatology.

Aberrant N-glycosylation of beta1 integrin causes reduced alpha5beta1 integrin clustering and stimulates cell migration.

S. Akiyama, M. Pierce, Intaek Lee, 2002, Cancer research.

p38 mitogen-activated protein kinase interacts with vinculin at focal adhesions during fatty acid-stimulated cell adhesion.

K. Olden, John D. Roberts, G. Kissling, 2013, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Formation of amyloid-like fibrils by self-association of a partially unfolded fibronectin type III module.

S. Aota, C. Haudenschild, S. Akiyama, 1998, Journal of molecular biology.

TNF-alpha binds to the N-terminal domain of fibronectin and augments the beta 1-integrin-mediated adhesion of CD4+ T lymphocytes to the glycoprotein.

R. Alon, K. Yamada, D. Wallach, 1994, Journal of immunology.

Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells.

E. M. Reyes-Reyes, S. Akiyama, E. Reyes-Reyes, 2008, Experimental cell research.

Substrate-specific binding of the amino terminus of fibronectin to an integrin complex in focal adhesions.

D. M. Peters, B. Dzamba, S. Akiyama, 1994, The Journal of biological chemistry.

Fibronectin and integrins in cell adhesion and migration.

S. Aota, K. Olden, K. Yamada, 1991, Biochemical Society transactions.

Activation of β1 Integrins Induces Cell–Cell Adhesion

S. Akiyama, J. Whittard, S. K. Akiyama, 2001 .

Induction of T cell adhesion to extracellular matrix or endothelial cell ligands by soluble or matrix‐bound interleukin‐7

Kenneth M. Yamada, R. Alon, T. Lapidot, 1997, European journal of immunology.

Vinexin: A Novel Vinculin-binding Protein with Multiple SH3 Domains Enhances Actin Cytoskeletal Organization

Kenneth M. Yamada, S. Aota, K. Okazaki, 1999, The Journal of cell biology.

Differences in the biosynthesis and localization of the fibronectin receptor in normal and transformed cultured human cells.

H. Larjava, K. Yamada, S. Akiyama, 1990, Cancer research.

Synthetic peptides competitively inhibit both direct binding to fibroblasts and functional biological assays for the purified cell-binding domain of fibronectin.

K. Yamada, S. Akiyama, Steven K. AkiyamaS, 1985, The Journal of biological chemistry.

Novel Function for Integrins in Keratinocyte Cell-Cell Interactions

Kenneth M. Yamada, H. Gralnick, H. Larjava, 2002 .

TNF-alpha associated with fibronectin enhances phorbol myristate acetate- or antigen-mediated integrin-dependent adhesion of CD4+ T cells via protein tyrosine phosphorylation.

S. Miron, R. Alon, K. Yamada, 1994, Journal of immunology.

Arachidonic Acid Activates Mitogen-activated Protein (MAP) Kinase-activated Protein Kinase 2 and Mediates Adhesion of a Human Breast Carcinoma Cell Line to Collagen Type IV through a p38 MAP Kinase-dependent Pathway*

K. Olden, John D. Roberts, S. Akiyama, 2000, The Journal of Biological Chemistry.

Identification of two distinct regions of an alternatively spliced site in human plasma fibronectin that promotes cell-type specific adhesion

M. Humphries, K. Olden, S. Akiyama, 1988 .

Activation of beta1 integrins induces cell-cell adhesion.

S. Akiyama, J. Whittard, 2001, Experimental cell research.

Activation of Protein Kinase C by Phorbol Esters Modulates α2β1Integrin on MCF-7 Breast Cancer Cells

R. Dickson, Michael D. Johnson, E. Rosfjord, 1999 .

A novel role for the T‐box transcription factor Tbx1 as a negative regulator of tumor cell growth in mice

R. Tennant, C. Bortner, John D. Roberts, 2011, Molecular carcinogenesis.

12-O-tetradecanoylphorbol 13-acetate stimulates human T-lymphocyte adherence to the fibronectin RGD domain and the laminin IKVAV domain.

H. Schnaper, H. Kleinman, P. Klotman, 1994, Cellular immunology.

Activation of protein kinase C by phorbol esters modulates alpha2beta1 integrin on MCF-7 breast cancer cells.

R. Dickson, E. Rosfjord, S. Akiyama, 1999, Experimental cell research.

BCL2 interaction with actin in vitro may inhibit cell motility by enhancing actin polymerization

Jennifer Y. Zhang, J. French, Hengning Ke, 2011, Cell adhesion & migration.

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function

Kenneth M. Yamada, S. Akiyama, S. Miyamoto, 1995, Science.

Lysine 63-linked ubiquitination is important for arachidonic acid-induced cellular adhesion and migration.

K. Olden, John D. Roberts, S. Akiyama, 2010, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Expression and ligand binding of alpha 2 beta 1 integrin on breast carcinoma cells.

R. Dickson, S. Akiyama, V. Woods, 1995, Clinical & experimental metastasis.

Fibronectin-a$, lntegrin Interaction

James, S. Akiyama, J., 2004 .