I. Agoulnik

发表

Role of SRC-1 in the promotion of prostate cancer cell growth and tumor progression.

Anna Frolov, M. Ittmann, Carolyn L. Smith, 2005, Cancer research.

Synthetic non‐peptide low molecular weight agonists of the relaxin receptor 1

Xin Hu, J. Marugan, I. Agoulnik, 2017, British journal of pharmacology.

Repressors of Androgen and Progesterone Receptor Action*

N. Weigel, W. Bingman, G. Ayala, 2003, Journal of Biological Chemistry.

Reduced Androgen Receptor Expression Accelerates the Onset of ERBB2 Induced Breast Tumors in Female Mice

I. Agoulnik, A. Agoulnik, R. Poppiti, 2013, PloS one.

Developmental Expression and Gene Regulation of Insulin-like 3 Receptor RXFP 2 in Mouse Male Reproductive Organs 1

C. Bishop, B. Korchin, T. Klonisch, 2007 .

Developmental Expression and Gene Regulation of Insulin-like 3 Receptor RXFP2 in Mouse Male Reproductive Organs1

C. Bishop, B. Korchin, T. Klonisch, 2007, Biology of reproduction.

Suppression of relaxin receptor RXFP1 decreases prostate cancer growth and metastasis.

C. Creighton, A. Sood, M. Ittmann, 2010, Endocrine-related cancer.

Relaxin Signaling in Uterine Fibroids

Matthew L. Anderson, A. Rajkovic, X. Tong, 2009, Annals of the New York Academy of Sciences.

Pim‐2 upregulation: Biological implications associated with disease progression and perinueral invasion in prostate cancer

T. Wheeler, T. Thompson, Rile Li, 2005, The Prostate.

A germline variation in the progesterone receptor gene increases transcriptional activity and may modify ovarian cancer risk.

D. Edwards, N. Weigel, D. Kieback, 2004, The Journal of clinical endocrinology and metabolism.

Comparison of Long-term Survival of Cytomegalovirus Promoter versus Rous Sarcoma Virus Promoter-Driven Thymidine Kinase Gene Therapy in Nude Mice Bearing Human Ovarian Cancer

C. Contant, A. Hasenburg, D. Kieback, 1999 .

A Genetic Mutation in the Progesterone Receptor (PROGINS) leads to an increased risk of non-familial breast and ovarian cancer causing inadequate control of estrogen receptor driven proliferation

N. Weigel, D. Kieback, I. Agoulnik, 1998 .

Oxidative DNA Damage Modulates DNA Methylation Pattern in Human Breast Cancer 1 (BRCA1) Gene via the Crosstalk between DNA Polymerase β and a de novo DNA Methyltransferase

Samuel H. Wilson, J. Horton, I. Agoulnik, 2020, Cells.

Androgen receptor signaling and vitamin D receptor action in prostate cancer cells

N. Weigel, I. Agoulnik, Shalini Murthy, 2005, The Prostate.

Developmental Expression and Gene Regulation of Insulin-like 3 Receptor RXFP2 in Mouse Male Reproductive Organs

C. Bishop, B. Korchin, T. Klonisch, 2007 .

Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile.

Catherine Z. Chen, M. Ferrer, Noel Southall, 2018, European journal of medicinal chemistry.

Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis

M. Ferrer, C. Bishop, Noel Southall, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Expression patterns and the roles of phosphatidylinositol phosphatases in testis

I. Agoulnik, A. Agoulnik, Y. Ceyhan, 2022, Biology of Reproduction.

Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2

M. Ferrer, Noel Southall, K. Wilson, 2022, Communications Biology.

Identification of Small-Molecule Agonists of Human Relaxin Family Receptor 1 (RXFP1) by Using a Homogenous Cell-Based cAMP Assay

Raisa E Jones, Catherine Z. Chen, M. Ferrer, 2013, Journal of biomolecular screening.

Relaxin/RXFP1 Signaling in Prostate Cancer Progression

A. Sood, M. Ittmann, G. Lopez-Berestein, 2009, Annals of the New York Academy of Sciences.

The role of relaxin in endometrial cancer

A. Sood, I. Agoulnik, F. Kheradmand, 2006, Cancer biology & therapy.

Coactivator selective regulation of androgen receptor activity

N. Weigel, I. Agoulnik, 2009, Steroids.

A novel androgen receptor mutant, A748T, exhibits hormone concentration-dependent defects in nuclear accumulation and activity despite normal hormone-binding affinity.

G. Buchanan, W. Tilley, Jonathan M. Harris, 2002, Molecular endocrinology.

INPP4B is an oncogenic regulator in human colon cancer

R. Scott, Y. Xi, H. Tseng, 2015, Oncogene.

INPP4B: the New Kid on the PI3K Block

M. Ittmann, I. Agoulnik, M. Hodgson, 2011, Oncotarget.

Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.

Leif E. Peterson, M. Ittmann, N. Weigel, 2011, Cancer research.

Tumor and Stem Cell Biology Decreased Expression and Androgen Regulation of the Tumor Suppressor Gene INPP 4 B in Prostate Cancer

Leif E. Peterson, M. Ittmann, N. Weigel, 2011 .

Coregulators and the Regulation of Androgen Receptor Action in Prostate Cancer

N. Weigel, I. Agoulnik, 2009 .

Androgen receptor coactivators and prostate cancer.

N. Weigel, I. Agoulnik, 2008, Advances in experimental medicine and biology.

Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer.

M. Ittmann, Carolyn L. Smith, N. Weigel, 2006, Cancer research.

Inositol Polyphosphate 4-phosphatase Type II Regulation of Androgen Receptor Activity

Leif E. Peterson, K. Rajapakshe, C. Coarfa, 2018, Oncogene.

Androgen Receptor and Poly(ADP-ribose) Glycohydrolase Inhibition Increases Efficiency of Androgen Ablation in Prostate Cancer Cells

I. Agoulnik, D. Ogilvie, I. Waddell, 2020, Scientific Reports.

Inhibition of base excision repair by natamycin suppresses prostate cancer cell proliferation.

I. Agoulnik, Y. Tse‐Dinh, Yuan Liu, 2019, Biochimie.

Androgen receptor footprint on the way to prostate cancer progression

I. Agoulnik, M. Hodgson, Wayne A. Bowden, 2011, World Journal of Urology.

Base Excision Repair of Chemotherapeutically-Induced Alkylated DNA Damage Predominantly Causes Contractions of Expanded GAA Repeats Associated with Friedreich's Ataxia

I. Agoulnik, Yuan Liu, Zunzhen Zhang, 2014, PloS one.

Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in mice

J. Vacher, I. Agoulnik, A. Agoulnik, 2020, PloS one.

A transgenic insertion upstream of Sox9 is associated with dominant XX sex reversal in the mouse

Paul A. Overbeek, Richard R. Behringer, Irina U. Agoulnik, 2000, Nature Genetics.

Targeted disruption of the p160 coactivator interface of androgen receptor (AR) selectively inhibits AR activity in both androgen-dependent and castration-resistant AR-expressing prostate cancer cells.

N. Weigel, I. Agoulnik, Manjula Nakka, 2013, The international journal of biochemistry & cell biology.

INPP 4 B suppresses prostate cancer cell invasion

Yuzhuo Wang, I. Gorlov, I. Agoulnik, 2019 .

Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression

Leif E. Peterson, K. Rajapakshe, M. Ittmann, 2016, Clinical Cancer Research.

INPP4B suppresses prostate cancer cell invasion

Yuzhuo Wang, I. Gorlov, I. Agoulnik, 2014, Cell Communication and Signaling.

Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities.

I. Agoulnik, B. Rosen, C. Packianathan, 2013, Biochemical and biophysical research communications.

Techniques for Evaluation of AR Transcriptional Output and Recruitment to DNA.

I. Agoulnik, Manqi Zhang, W. Krause, 2018, Methods in molecular biology.

Target Gene-specific Regulation of Androgen Receptor Activity by P42/p44 Mitogen-activated Protein Kinase

X. Liu, Wei Li, Qianben Wang, 2008 .

INPP4B protects from metabolic syndrome and associated disorders

J. Vacher, M. Ittmann, F. Knop, 2021, Communications Biology.

INPP4B protects from metabolic syndrome and associated disorders

J. Vacher, M. Ittmann, F. Knop, 2021, Communications Biology.

Relaxin Promotes Prostate Cancer Progression

M. Ittmann, Rile Li, G. Ayala, 2007, Clinical Cancer Research.

Androgen receptor action in hormone‐dependent and recurrent prostate cancer

N. Weigel, I. Agoulnik, Nancy L. Weigel, 2006, Journal of cellular biochemistry.

Roles of Androgen Receptor Coregulators and Cell Signaling in the Regulation of Androgen-Responsive Genes

N. Weigel, I. Agoulnik, 2013 .

Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility

Adam T. Szafran, J. Price, N. Weigel, 2006, Journal of cellular biochemistry.

Improvement of gene therapy for ovarian cancer by using acyclovir instead of ganciclovir in adenovirus mediated thymidine kinase gene therapy.

C. Contant, A. Hasenburg, D. Kieback, 1998, Anticancer research.

Editorial: Sphingolipid metabolism and cancer

M. Lleonart, I. Agoulnik, Margarita M Ivanova, 2022, Frontiers in Oncology.

Human epithelial ovarian cancer xenotransplants into nude mice can be cured by adenovirus-mediated thymidine kinase gene therapy.

K. Blankenburg, C. Contant, E. Stickeler, 1997, Anticancer research.

Adenovirus mediated thymidine kinase gene therapy may enhance sensitivity of ovarian cancer cells to chemotherapeutic agents.

A. Hasenburg, D. Kieback, S. Woo, 1998, Anticancer research.

In vivo gene therapy of ovarian cancer by adenovirus-mediated thymidine kinase gene transduction and ganciclovir administration.

K. Blankenburg, C. Contant, D. Kieback, 1996, Gynecologic oncology.

Multiferroic coreshell magnetoelectric nanoparticles as NMR sensitive nanoprobes for cancer cell detection

R. Guduru, S. Khizroev, I. Agoulnik, 2017, Scientific Reports.

Human Relaxin Receptor Is Fully Functional in Humanized Mice and Is Activated by Small Molecule Agonist ML290

Javier J. How, J. Marugan, C. Yoo, 2017, Journal of the Endocrine Society.

Activation of Relaxin Family Receptor 1 from Different Mammalian Species by Relaxin Peptide and Small-Molecule Agonist ML290

M. Ferrer, Noel Southall, Xin Hu, 2015, Front. Endocrinol..

Telomere length in human white blood cells remains constant with age and is shorter in breast cancer patients.

E. Atkinson, I. Runnebaum, E. Stickeler, 1998, Anticancer research.

The efficacy of adenovirus-mediated gene therapy of ovarian cancer is enhanced by using the cytomegalovirus promoter.

C. Contant, Z. Guo, A. Hasenburg, 1998, Anticancer research.

Structural Insights into the Activation of Human Relaxin Family Peptide Receptor 1 by Small-Molecule Agonists.

M. Ferrer, Noel Southall, Xin Hu, 2016, Biochemistry.

Androgen Receptor and Poly(ADP-ribose) Glycohydrolase Inhibition Increases Efficiency of Androgen Ablation in Prostate Cancer Cells

I. Agoulnik, D. Ogilvie, I. Waddell, 2020, Scientific Reports.

Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1

Raisa E Jones, Catherine Z. Chen, M. Ferrer, 2013, Nature Communications.

Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities.

I. Agoulnik, B. Rosen, C. Packianathan, 2013, Biochemical and Biophysical Research Communications - BBRC.

FIU Digital Commons FIU Digital Commons

H. Tempest, I. Agoulnik, G. Anifandis, 2022 .

Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.

Leif E. Peterson, M. Ittmann, N. Weigel, 2011, Cancer research.

Regulation of EZH2 Expression by INPP4B in Normal Prostate and Primary Prostate Cancer

I. Agoulnik, Taghreed Hirz, Manqi Zhang, 2023, Cancers.

Long-Lasting Consequences of Testosterone Exposure.

I. Agoulnik, A. Agoulnik, 2015, Endocrinology.