K. Sengmany

发表

Metabotropic glutamate receptor subtype 5: molecular pharmacology, allosteric modulation and stimulus bias

K. Gregory, K. Sengmany, K J Gregory, 2016, British journal of pharmacology.

Kinetic and system bias as drivers of metabotropic glutamate receptor 5 allosteric modulator pharmacology

K. Gregory, A. Christopoulos, L. May, 2019, Neuropharmacology.

Probe dependence and biased potentiation of metabotropic glutamate receptor 5 is mediated by differential ligand interactions in the common allosteric binding site.

K. Gregory, A. Christopoulos, K. Sengmany, 2020, Biochemical pharmacology.

Metabotropic glutamate receptor 5 (mGlu5)‐positive allosteric modulators differentially induce or potentiate desensitization of mGlu5 signaling in recombinant cells and neurons

K. Gregory, K. Sengmany, K. Leach, 2019, Journal of Neurochemistry.

Ambient temperature modulates the effects of the Prader-Willi syndrome candidate gene Snord116 on energy homeostasis

Lei Zhang, H. Herzog, A. Sainsbury, 2017, Neuropeptides.

Drugs to Tune Up Glutamatergic Systems: Modulators of Glutamate Metabotropic Receptors

K. Gregory, K. Sengmany, 2018 .

Kinetics of ligand binding and signaling

N. Holliday, S. Charlton, K. Sengmany, 2020 .

Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery

K. Gregory, A. Christopoulos, P. Conn, 2017, Neuropharmacology.

Differential contribution of metabotropic glutamate receptor 5 common allosteric binding site residues to biased allosteric agonism.

K. Gregory, A. Christopoulos, K. Sengmany, 2020, Biochemical pharmacology.