B. Lüscher

B. Lüscher, A. Fallarero, L. Lehtiö, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter

A. Friedman, M. Oelgeschläger, B. Lüscher, 1996, Molecular and cellular biology.

Mad1 Function in Cell Proliferation and Transcriptional Repression Is Antagonized by Cyclin E/CDK2*

E. Kremmer, M. Eilers, C. Bouchard, 2005, Journal of Biological Chemistry.

Histone-specific RNA 3' processing in nuclear extracts from mammalian cells.

D. Soldati, D. Schümperli, B. Lüscher, 1990, Methods in enzymology.

Intramolecular hydrophobic interactions are critical mediators

D. Fahrenkamp, G. Rossetti, B. Lüscher, 2017 .

c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock

R. Eisenman, B. Lüscher, 1988, Molecular and cellular biology.

Characterization of a human TSPY promoter

J. Schmidtke, B. Lüscher, K. Nayernia, 2005, Molecular and Cellular Biochemistry.

Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.

L. Ratner, C. Robson, M. Henriksson, 2015, Virology.

GODZ-Mediated Palmitoylation of GABAA Receptors Is Required for Normal Assembly and Function of GABAergic Inhibitory Synapses

C. Keller, M. Fukata, Y. Fukata, 2006, The Journal of Neuroscience.

The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ.

C. Keller, M. Sassoè-Pognetto, M. Alldred, 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.

The gamma 2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses.

I. Mansuy, H. Bluethmann, C. Schweizer, 2003, Molecular and cellular neurosciences.

Mono-ADP-ribosylation by ARTD10 restricts Chikungunya virus replication by interfering with the proteolytic activity of nsP2

B. Lüscher, C. Goffinet, F. Pott, 2020, bioRxiv.

ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation

Anne K. Braczynski, E. Kremmer, B. Lüscher, 2013, Cell Communication and Signaling.

Knockdown of GABA(A) receptor signaling in GnRH neurons has minimal effects upon fertility.

B. Lüscher, A. Herbison, R. Campbell, 2010, Endocrinology.

IL-31 expression by inflammatory cells is preferentially elevated in atopic dermatitis.

B. Lüscher, J. Baron, 2012, Acta dermato-venereologica.

JAK1/3 inhibition preserves epidermal morphology in full‐thickness 3D skin models of atopic dermatitis and psoriasis

J. Gutermuth, B. Lüscher, I. Kortekaas Krohn, 2019, Journal of the European Academy of Dermatology and Venereology : JEADV.

Y-box protein 1 mediates PDGF-B effects in mesangioproliferative glomerular disease.

F. Eitner, P. Mertens, B. Lüscher, 2005, Journal of the American Society of Nephrology : JASN.

Myc/Max/Mad regulate the frequency but not the duration of productive cell cycles

D. Eick, B. Lüscher, M. Hölzel, 2001, EMBO reports.

Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l

I. Costa, S. Koschmieder, B. Lüscher, 2018, Scientific Reports.

Ubiquitination, proteasomes and GABAA receptors

C. Keller, B. Lüscher, 2001, Nature Cell Biology.

The E7 protein of human papillomavirus type 16 is phosphorylated by casein kinase II.

R. Eisenman, D. Galloway, B. Lüscher, 1989, The New biologist.

Cytokine-induced inhibition of Myc activity in monocytic cells.

L. Larsson, F. Bahram, B. Lüscher, 1997, Current topics in microbiology and immunology.

Casein kinase II as a potentially important enzyme concerned with signal transduction.

E. Krebs, R. Eisenman, D. Litchfield, 1988, Cold Spring Harbor symposia on quantitative biology.

Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo

J. Benson, H. Bluethmann, J. Fritschy, 1999 .

Analysis of Myc/Max/Mad network members in adipogenesis: Inhibition of the proliferative burst and differentiation by ectopically expressed Mad1

R. Eisenman, G. McArthur, A. Sommer, 2000, Journal of cellular physiology.

Analysis of the max‐binding protein MNT in human medulloblastomas

J. Tonn, R. Eisenman, A. Sommer, 1999, International journal of cancer.

Differential effects by Mad and Max on transformation by cellular and viral oncoproteins.

C. Seelos, M. Henriksson, C. Cerni, 1995, Oncogene.

Expression and regulation of protein kinase CK2 during the cell cycle

D. Litchfield, B. Lüscher, D. Bosc, 2004, Molecular and Cellular Biochemistry.

A second c-myb protein is translated from an alternatively spliced mRNA expressed from normal and 5'-disrupted myb loci

R. Eisenman, B. Lüscher, G. Shen-Ong, 1989, Molecular and cellular biology.

Protein and RNA ADP-ribosylation detection is influenced by sample preparation and reagents used

D. Filippov, B. Lüscher, R. Žaja, 2022, Life Science Alliance.

SH3TC2, a protein mutant in Charcot-Marie-Tooth neuropathy, links peripheral nerve myelination to endosomal recycling.

U. Suter, D. Litchfield, J. Senderek, 2010, Brain : a journal of neurology.

A role for the p34cdc2 kinase and phosphatases in the regulation of phosphorylation and disassembly of lamin B2 during the cell cycle.

D. Beach, L. Brizuela, B. Lüscher, 1991, The EMBO journal.

The Ins and Outs of MYC Regulation by Posttranslational Mechanisms*

B. Lüscher, J. Lüscher-Firzlaff, J. Vervoorts, 2006, Journal of Biological Chemistry.

Ultraviolet B radiation and reactive oxygen species modulate interleukin‐31 expression in T lymphocytes, monocytes and dendritic cells

A. Kim, D. Bickers, B. Lüscher, 2011, The British journal of dermatology.

Regulatory domains of the A-Myb transcription factor and its interaction with the CBP/p300 adaptor molecules.

M. Oelgeschläger, B. Lüscher, V. Facchinetti, 1997, The Biochemical journal.

Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels

B. Lüscher, F. Dong, C. Long, 2019, Molecular Brain.

GABAergic Control of Adult Hippocampal Neurogenesis in Relation to Behavior Indicative of Trait Anxiety and Depression States

Shigeyoshi Itohara, Bernhard Lüscher, Takuji Iwasato, 2007, The Journal of Neuroscience.

The mono-ADP-ribosyltransferase ARTD10 regulates the voltage-gated K+ channel Kv1.1 through protein kinase C delta

C. Bolm, B. Lüscher, B. Falkenburger, 2020, BMC Biology.

Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors.

A. Aguzzi, J. Benson, H. Bluethmann, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.

C. Keller, B. Lüscher, 2004, Pharmacology & therapeutics.

Postsynaptic clustering of major GABAA receptor subtypes requires the γ2 subunit and gephyrin

Bernhard Lüscher, J. Benson, M. Lorez, 1998, Nature Neuroscience.

IL-31 regulates differentiation and filaggrin expression in human organotypic skin models.

B. Lüscher, J. Wenzel, J. Lüscher-Firzlaff, 2012, The Journal of allergy and clinical immunology.

The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function

B. Lüscher, J. Baron, Y. Marquardt, 2017, Scientific Reports.

Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.

R. Tjian, P. Mitchell, B. Lüscher, 1989, Genes & development.

Negative charge at the casein kinase II phosphorylation site is important for transformation but not for Rb protein binding by the E7 protein of human papillomavirus type 16.

R. Eisenman, B. Lüscher, J. Firzlaff, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Cytokines and the Skin Barrier

B. Lüscher, J. Baron, C. Cornelissen, 2013, International journal of molecular sciences.

Myc oncoproteins are phosphorylated by casein kinase II.

E. Krebs, B. Lüscher, B Lüscher, 1989, The EMBO journal.

The search for inhibitors of macrodomains for targeting the readers and erasers of mono-ADP-ribosylation.

B. Lüscher, Wei Fu, Qianqian Zhao, 2021, Drug discovery today.

The conserved macrodomains of the non-structural proteins of Chikungunya virus and other pathogenic positive strand RNA viruses function as mono-ADP-ribosylhydrolases

G. Rossetti, B. Lüscher, B. Kümmerer, 2017, Scientific Reports.

Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

Bernhard Lüscher, Herwig Schüler, F. Koch-Nolte, 2010, Trends in biochemical sciences.

Mitosis-specific phosphorylation of the nuclear oncoproteins Myc and Myb

R. Eisenman, B. Lüscher, Bernhard Lüscher, 1992, The Journal of cell biology.

A Selenium‐Based Click AdoMet Analogue for Versatile Substrate Labeling with Wild‐Type Protein Methyltransferases

E. Weinhold, B. Lüscher, Michael Martin, 2012, Chembiochem : a European journal of chemical biology.

Enzymatic site-specific functionalization of protein methyltransferase substrates with alkynes for click labeling.

Kelly E. Duncan, D. Litchfield, E. Weinhold, 2010, Angewandte Chemie.

Proteins of the Myc network: essential regulators of cell growth and differentiation.

M. Henriksson, B. Lüscher, B Lüscher, 1996, Advances in cancer research.

Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes reduces chromatin accessibility at promoters

I. Costa, B. Lüscher, J. Lüscher-Firzlaff, 2022, Scientific reports.

Structural prediction of the interaction of the tumor suppressor p27KIP1 with cyclin A/CDK2 identifies a novel catalytically relevant determinant

Jinyu Li, Paolo Carloni, Jörg Vervoorts, 2017, BMC Bioinformatics.

Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin

B. Lüscher, J. Lüscher-Firzlaff, Agnieszka Bochyńska, 2018, Cells.

Targeting insulin-like growth factor - I receptor in breast cancer

B. Litzenburger, B. Lüscher, 2011 .

Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

E. Krebs, R. Eisenman, D. Litchfield, 1990, Nature.

Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements.

R. Tjian, A. Admon, B. Lüscher, 1988, Genes & development.

MAD1 and its life as a MYC antagonist: an update.

B. Lüscher, 2012, European journal of cell biology.

Regulation of the MAD1 promoter by G-CSF

Bernhard Lüscher, B. Lüscher, Kan Jiang, 2008, Nucleic acids research.

Regulation of the potential tumorsuppressor gene mad1 by G-CSF

B. Lüscher, Kan Jiang, 2006 .

The Mad side of the Max network: antagonizing the function of Myc and more.

B. Lüscher, S. Rottmann, Bernhard Lüscher, 2006, Current topics in microbiology and immunology.

Repression of in vivo growth of Myc/Ras transformed tumor cells by Mad1

M. Henriksson, C. Cerni, L. Larsson, 2002, Oncogene.

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

E. Guccione, B. Amati, Fabio Casadio, 2007, Nature.

Stimulation of c‐MYC transcriptional activity and acetylation by recruitment of the cofactor CBP

B. Lüscher, R. Lilischkis, M. Austen, 2003, EMBO reports.

Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation

M. Henriksson, L. Larsson, A. Grandien, 2009, Proceedings of the National Academy of Sciences.

C‐MYC expression in medulloblastoma and its prognostic value

P. Schürmann, F. Hanefeld, H. Kretzschmar, 2000, International journal of cancer.

YY1 binding to a subset of p53 DNA-target sites regulates p53-dependent transcription.

T. Ekström, T. Yakovleva, K. Tan-No, 2004, Biochemical and biophysical research communications.

The Transcription Factor YY1 Is a Substrate for Polo-Like Kinase 1 at the G2/M Transition of the Cell Cycle

M. Hurt, B. Lüscher, R. Rizkallah, 2011, PloS one.

H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.

E. Kremmer, T. Höller, R. Büttner, 2010, Human pathology.

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop

A. Menssen, H. Hermeking, L. Larsson, 2011, Proceedings of the National Academy of Sciences.

Basic Concepts of Tumor Biology

A. Nordheim, B. Lüscher, 2000 .

Regulation of Sirtuin Function by Posttranslational Modifications

B. Lüscher, Franziska Flick, 2012, Front. Pharmacol..

New light on Myc and Myb. Part II. Myb.

R. Eisenman, B. Lüscher, Bernhard Lüscher, 1990, Genes & development.

Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.

R. Tjian, N. Mermod, A. Admon, 1990, Genes & development.

Inhibition of SIRT2 suppresses hepatic fibrosis.

P. Breslin, B. Lüscher, S. Cotler, 2016, American journal of physiology. Gastrointestinal and liver physiology.

Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter.

M. Eilers, C. Bouchard, B. Lüscher, 2001, Genes & development.

The basic region/helix – loop – helix/leucine zipper domain of Myc proto-oncoproteins: Function and regulation

L. Larsson, B. Lüscher, 1999, Oncogene.

Inhibition of apoptosis by MAD1 is mediated by repression of the PTEN tumor suppressor gene

B. Lüscher, J. Lüscher-Firzlaff, S. Rottmann, 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Studies on a novel poly(ADP-ribosyl)ation polymerase PARP-10 and its functional interaction with c-Myc

B. Lüscher, Mei Yu, 2005 .

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

E. Kremmer, A. Sommer, B. Lüscher, 1997, Current Biology.

Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62

E. Kremmer, G. Müller-Newen, A. Herrmann, 2012, Cell Communication and Signaling.

TGFβ1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors

B. Lüscher, Kan Jiang, Nadine Hein, 2011, BMC Molecular Biology.

TGF b 1 enhances MAD 1 expression and stimulates promoter-bound Pol II phosphorylation : basic functions of C / EBP , SP and SMAD 3 transcription factors

B. Lüscher, Kan Jiang, Nadine Hein, 2011 .

Mechanistic insights into the PARP10-mediated ADP-ribosylation reaction and analysis of PARP10's subcellular localization

B. Lüscher, Henning Schuchlautz, 2008 .

Overlap of the gene encoding the novel poly(ADP-ribose) polymerase Parp10 with the plectin 1 gene and common use of exon sequences.

B. Lüscher, G. Wiche, P. Fuchs, 2005, Genomics.

Inhibition of Proliferation and Apoptosis by the Transcriptional Repressor Mad1

B. Lüscher, A. Menkel, A. Krippner-Heidenreich, 2000, The Journal of Biological Chemistry.

DNA Binding of Myc/Max/Mad Network Complexes to Oligonucleotides Containing Two E Box Elements: c-Myc/Max Heterodimers Do Not Bind DNA Cooperatively

B. Lüscher, J. Vervoorts, 1999, Biological chemistry.

Identification and Characterization of Specific DNA-binding Complexes Containing Members of the Myc/Max/Mad Network of Transcriptional Regulators*

E. Kremmer, A. Sommer, B. Lüscher, 1998, The Journal of Biological Chemistry.

Characterization of the Transcriptional Regulator YY1

Bernhard Lüscher, B. Lüscher, M. Austen, 1997, The Journal of Biological Chemistry.

Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc.

L. Larsson, M. Pettersson, B. Lüscher, 1994, Oncogene.

Identification of casein kinase II phosphorylation sites in Max: effects on DNA-binding kinetics of Max homo- and Myc/Max heterodimers.

M. Henriksson, D. Litchfield, B. Lüscher, 1993, Oncogene.

Mutational analysis of the carboxy-terminal casein kinase II phosphorylation site in human c-myc.

R. Eisenman, B. Lüscher, E. Blackwood, 1990, Current topics in microbiology and immunology.

Synergistic activation of the mkp‐1 gene by protein kinase A signaling and USF, but not c‐Myc

A. Sommer, S. Keyse, B. Lüscher, 2000, FEBS letters.

Caspase‐dependent cleavage of the mono‐ADP‐ribosyltransferase ARTD10 interferes with its pro‐apoptotic function

E. Kremmer, B. Lüscher, Henning Kleine, 2013, The FEBS journal.

The human trithorax protein hASH2 functions as an oncoprotein.

E. Kremmer, C. Cerni, A. Wellmann, 2008, Cancer research.

The GDP-GTP Exchange Factor Collybistin: An Essential Determinant of Neuronal Gephyrin Clustering

M. Owen, Ian Duguid, M. Alldred, 2004, The Journal of Neuroscience.

SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310

B. Lüscher, M. Hottiger, Suheda Erener, 2010, Journal of Cell Science.

SIRT 2 regulates NFk B-dependent gene expression through deacetylation of p 65 Lys 310

B. Lüscher, M. Hottiger, Suheda Erener, 2010 .

Neuronal subtype-specific expression directed by the GABA(A) receptor delta subunit gene promoter/upstream region in transgenic mice and in cultured cells.

T. Rülicke, J. Fritschy, B. Lüscher, 1997, Brain research. Molecular brain research.

Palmitoylation of Gephyrin Controls Receptor Clustering and Plasticity of GABAergic Synapses

J. Meier, T. Lamkemeyer, G. Schwarz, 2014, PLoS biology.

The highly conserved DNA-binding domains of A-, B- and c-Myb differ with respect to DNA-binding, phosphorylation and redox properties.

B. Lüscher, K. Andersson, O. Gabrielsen, 2001, Nucleic acids research.

Characterisation of the role of ING5

B. Lüscher, Poornima Basavarajaiah, 2005 .

ING5 Is Phosphorylated by CDK2 and Controls Cell Proliferation Independently of p53

Jörg Vervoorts, Bernhard Lüscher, Andrea Ullius, 2015, PloS one.

Revisiting a selection of target genes for the hematopoietic transcription factor c-Myb using chromatin immunoprecipitation and c-Myb knockdown.

B. Lüscher, O. Gabrielsen, V. Matre, 2007, Blood cells, molecules & diseases.

IL-31 - a regulator of skin differentiation

B. Lüscher, C. Cornelissen, 2011 .

RNA 3′ processing regulates histone mRNA levels in a mammalian cell cycle mutant. A processing factor becomes limiting in G1‐arrested cells.

D. Schümperli, B. Lüscher, 1987, The EMBO journal.

New light on Myc and Myb. Part I. Myc.

R. Eisenman, B. Lüscher, Bernhard Luscher, 1990, Genes & development.

The GABAA receptors. From subunits to diverse functions.

J. Benson, J. Fritschy, H. Mohler, 1996, Ion channels.

Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation

Bernhard Lüscher, B. Lüscher, Patricia Verheugd, 2013, Nature Reviews Molecular Cell Biology.

Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l

I. Costa, S. Koschmieder, B. Lüscher, 2019, Scientific Reports.

Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis. Oncotarget,

G. Müller-Newen, D. Fahrenkamp, B. Lüscher, 2016 .

Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity

E. Dahl, J. Bernhagen, H. Lue, 2007, Oncogene.

A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation

Reinhard Ullmann, Cheng Fang, Kirsten Harvey, 2009, Human mutation.

GABAergic Terminals Are Required for Postsynaptic Clustering of Dystrophin But Not of GABAA Receptors and Gephyrin

I. Knuesel, J. Fritschy, I. Brünig, 2002, The Journal of Neuroscience.

Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin.

J. Benson, M. Lorez, J. Fritschy, 1998, Nature neuroscience.

Signaling by IL-31 and functional consequences.

Bernhard Lüscher, B. Lüscher, Christian Cornelissen, 2012, European journal of cell biology.

The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

Jörg Vervoorts, Bernhard Lüscher, Edwin Lasonder, 2008, The Journal of cell biology.

Effect of C-Terminal S-Palmitoylation on D2 Dopamine Receptor Trafficking and Stability

V. Wong, R. Levenson, I. Stagljar, 2015, PloS one.

AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

S. Geley, D. Neumann, D. Chanda, 2020, Nature Communications.

The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site

W. Becker, B. Lüscher, R. Lilischkis, 2006, BMC Biochemistry.

PARP10 (ARTD10) modulates mitochondrial function

M. Antal, B. Lüscher, P. Bai, 2018, PloS one.

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

D. Litchfield, B. Lüscher, M. Hottiger, 2008, Molecular cell.

Bacterial Growth Inhibition Screen (BGIS): harnessing recombinant protein toxicity for rapid and unbiased interrogation of protein function

B. Lüscher, F. Kappes, B. Hermanns-Sachweh, 2021, FEBS letters.

Sulfoximines as ATR inhibitors: Analogs of VE-821.

C. Bolm, G. Rossetti, B. Lüscher, 2017, Bioorganic & medicinal chemistry letters.

The Golden Hamster Aphrodisin Gene

B. Lüscher, W. Forssmann, O. Alkan, 1999, The Journal of Biological Chemistry.

Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes

I. Costa, B. Lüscher, J. Lüscher-Firzlaff, 2022, bioRxiv.

Faithful cell-cycle regulation of a recombinant mouse histone H4 gene is controlled by sequences in the 3'-terminal part of the gene.

D. Schümperli, B. Lüscher, R. Schindler, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Bacterial Growth Inhibition Screen (BGIS) identifies a loss‐of‐function mutant of the DEK oncogene, indicating DNA modulating activities of DEK in chromatin

E. Ferrando-May, B. Lüscher, F. Kappes, 2021, FEBS letters.

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases

A. Caflisch, B. Lüscher, M. Hottiger, 2013, Nature Structural &Molecular Biology.

Diversity in Structure, Pharmacology, and Regulation of GABAA Receptors

J. Benson, J. Fritschy, B. Lüscher, 1997 .

Phosphorylation of the Transcription Factor YY1 by CK2α Prevents Cleavage by Caspase 7 during Apoptosis

M. Hurt, B. Lüscher, R. Rizkallah, 2011, Molecular and Cellular Biology.

The Mad1 transcription factor is a novel target of activin and TGF-β action in keratinocytes: possible role of Mad1 in wound repair and psoriasis

S. Werner, B. Lüscher, C. Mauch, 2001, Oncogene.

The transcription factor Yin Yang 1 is an activator of BACE1 expression

K. Nowak, A. Robitzki, B. Lüscher, 2006, Journal of neurochemistry.

CD73/Ecto-5′-Nucleotidase Protects Against Vascular Inflammation and Neointima Formation

A. Zernecke, C. Weber, J. Schrader, 2006, Circulation.

Role of STAT3 N-terminal domain and GAS-site recognition in signaling and crosstalk with STAT1 and NF-κB

G. Müller-Newen, M. Zenke, B. Lüscher, 2017 .

ADP-ribosylation of RNA and DNA: from in vitro characterization to in vivo function

B. Lüscher, R. Žaja, Jeffrey Momoh, 2021, Nucleic acids research.

ADP-Ribosylation, a Multifaceted Posttranslational Modification Involved in the Control of Cell Physiology in Health and Disease.

B. Lüscher, B. Shilton, Laura Eckei, 2017, Chemical reviews.

Establishment of an Intradermal Ear Injection Model of IL-17A and IL-36γ as a Tool to Investigate the Psoriatic Cytokine Network

B. Lüscher, Ali T. Abdallah, J. Baron, 2021, Life.

The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function

B. Lüscher, J. Baron, Y. Marquardt, 2017, Scientific Reports.

Post-translational regulation of the tumor suppressor p27KIP1

B. Lüscher, J. Vervoorts, 2008, Cellular and Molecular Life Sciences.

Evaluation of 3‐ and 4‐Phenoxybenzamides as Selective Inhibitors of the Mono‐ADP‐Ribosyltransferase PARP10

C. Bolm, G. Rossetti, Albert Galera‐Prat, 2021, ChemistryOpen.

4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10.

B. Lüscher, Serena Massari, O. Tabarrini, 2018, European journal of medicinal chemistry.

ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation

Anne K. Braczynski, E. Kremmer, B. Lüscher, 2013, Cell Communication and Signaling.

PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1

B. Lüscher, O. Krämer, J. Hartkamp, 2019, Scientific Reports.

Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription

A. von Kriegsheim, G. Müller-Newen, C. Preisinger, 2018, Scientific Reports.

Expanding functions of intracellular resident mono‐ADP‐ribosylation in cell physiology

Bernhard Lüscher, B. Lüscher, Patricia Verheugd, 2013, The FEBS journal.

Paradox of sonic hedgehog (SHH) transcriptional regulation: Alternative transcription initiation overrides the effect of downstream promoter DNA methylation

E. Dahl, J. Veeck, R. Knüchel, 2011, Epigenetics.

Decreased GABAA-receptor clustering results in enhanced anxiety and a bias for threat cues

Bernhard Lüscher, Dietmar Benke, J. Laurent, 1999, Nature Neuroscience.

IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell‐death mediator receptor‐interacting protein kinase 1

T. Luedde, F. Tacke, C. Trautwein, 2016, Hepatology.

Casein kinase II phosphorylation site mutations in c-Myb affect DNA binding and transcriptional cooperativity with NF-M

M. Oelgeschläger, B. Lüscher, J. Krieg, 1995, Molecular and cellular biology.

Targeted Inactivation of a Developmentally Regulated Neural Plectin Isoform (Plectin 1c) in Mice Leads to Reduced Motor Nerve Conduction Velocity*

H. Lassmann, B. Lüscher, S. Reipert, 2009, The Journal of Biological Chemistry.

Insight into the Mechanism of Intramolecular Inhibition of the Catalytic Activity of Sirtuin 2 (SIRT2)

Paolo Carloni, Giulia Rossetti, Bernhard Lüscher, 2015, PloS one.

Gastroprotective peptide trefoil factor family 2 gene is activated by upstream stimulating factor but not by c-Myc in gastrointestinal cancer cells

N. Blin, B. Lüscher, J. Vervoorts, 2002, Gut.

Transcriptional Activity of GLI1 Is Negatively Regulated by Protein Kinase A

S. Kaesler, U. Rüther, B. Lüscher, 2000, Biological chemistry.

Analysis of the DNA-binding activities of Myc/Max/Mad network complexes during induced differentiation of U-937 monoblasts and F9 teratocarcinoma cells

L. Larsson, F. Bahram, B. Lüscher, 1997, Oncogene.

Subcellular localization and regulation of GABAA receptors and associated proteins.

J. Fritschy, B. Lüscher, Bernhard Luscher, 2001, International review of neurobiology.

The Myc:Max protein complex and cell growth regulation.

R. Eisenman, L. Kretzner, B. Lüscher, 1991, Cold Spring Harbor symposia on quantitative biology.

Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains.

Bianca Nijmeijer, Bernhard Lüscher, Henning Kleine, 2013, Structure.

Autoradiographic imaging of altered synaptic αβγ2 and extrasynaptic αβ GABAA receptors in a genetic mouse model of anxiety

B. Lüscher, E. Korpi, S. Sinkkonen, 2004, Neurochemistry International.

GABAA-receptor subtypes in vivo: cellular localization, pharmacology and regulation.

J. Benson, J. Fritschy, H. Mohler, 1995, Advances in biochemical psychopharmacology.

Single‐channel properties of neuronal GABAA receptors from mice lacking the γ2 subunit

J. Benson, M. Lorez, B. Lüscher, 2000, The Journal of physiology.

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

A. Plückthun, J. Grossmann, B. Lüscher, 2020, Nature Communications.

Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation

O. Frings, L. Larsson, P. Hydbring, 2015, Oncotarget.

Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication

B. Lüscher, C. Goffinet, F. Pott, 2023, Cellular and Molecular Life Sciences.

Correction: SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310 (doi:10.1242/jcs.073783)

B. Lüscher, M. Hottiger, Suheda Erener, 2019, Journal of Cell Science.

The role of IL-31 in skin barrier formation

D. Ostareck, B. Lüscher, K. Hänel, 2015 .

Behavioural changes produced by transgenic overexpression of γ2L and γ2S subunits of the GABAA receptor

R. Radcliffe, R. Harris, M. Wick, 2000 .

Brexanolone, a neurosteroid antidepressant, vindicates the GABAergic deficit hypothesis of depression and may foster resilience

B. Lüscher, H. Möhler, 2019, F1000Research.

Distinct γ2 Subunit Domains Mediate Clustering and Synaptic Function of Postsynaptic GABAA Receptors and Gephyrin

M. Alldred, B. Lüscher, Gong Chen, 2005, The Journal of Neuroscience.

Successful omalizumab treatment in chronic spontaneous urticaria is associated with lowering of serum IL‐31 levels

B. Lüscher, M. Maurer, M. Church, 2016, Journal of the European Academy of Dermatology and Venereology : JEADV.

Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription

A. von Kriegsheim, G. Müller-Newen, C. Preisinger, 2018, Scientific Reports.

Behavioural changes produced by transgenic overexpression of gamma2L and gamma2S subunits of the GABAA receptor.

R. Radcliffe, R. Harris, M. Wick, 2000, The European journal of neuroscience.

Enhanced Sampling Approach to the Induced-Fit Docking Problem in Protein-Ligand Binding: The Case of Mono-ADP-Ribosylation Hydrolase Inhibitors.

P. Carloni, Riccardo Capelli, G. Rossetti, 2021, Journal of chemical theory and computation.

An Enhanced Sampling Approach to the Induced Fit Docking Problem in Protein-Ligand Binding: the case of mono-ADP-ribosylation hydrolases inhibitors

P. Carloni, Riccardo Capelli, G. Rossetti, 2021, bioRxiv.

Endotoxin tolerance in mast cells, its consequences for IgE-mediated signalling, and the effects of BCL3 deficiency

M. Huber, M. Lesina, H. Algül, 2017, Scientific Reports.

PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1

B. Lüscher, O. Krämer, J. Hartkamp, 2019, Scientific Reports.

Activation of the GABA(A)-receptor delta-subunit gene promoter following pentylenetetrazole-induced seizures in transgenic mice.

J. Fritschy, B. Lüscher, F. Crestani, 1997, Brain research. Molecular brain research.

Studying the Role of AMPK in Autophagy.

B. Lüscher, J. Vervoorts, Sarah Krieg, 2018, Methods in molecular biology.

Tissue-specific expression of a FMR1/beta-galactosidase fusion gene in transgenic mice.

M. Gassmann, A. Aguzzi, T. Rülicke, 1995, Human molecular genetics.

Structural prediction of the interaction of the tumor suppressor p27KIP1 with cyclin A/CDK2 identifies a novel catalytically relevant determinant

P. Carloni, G. Rossetti, B. Lüscher, 2017, BMC Bioinformatics.

Mono-ADP-ribosylation by PARP10 inhibits Chikungunya virus nsP2 proteolytic activity and viral replication

B. Lüscher, C. Goffinet, F. Pott, 2023, Cellular and Molecular Life Sciences.

Players in ADP-ribosylation: Readers and Erasers.

B. Lüscher, Laura Eckei, Patricia Verheugd, 2016, Current protein and peptide science.

Assessment of Intracellular Auto-Modification Levels of ARTD10 Using Mono-ADP-Ribose-Specific Macrodomains 2 and 3 of Murine Artd8.

G. Rossetti, B. Lüscher, Laura Eckei, 2018, Methods in molecular biology.

Comparative analysis of MACROD1, MACROD2 and TARG1 expression, localisation and interactome

B. Lüscher, R. Feederle, R. Žaja, 2020, Scientific Reports.

The mono-ADP-ribosyltransferase ARTD10 regulates the voltage-gated K+ channel Kv1.1 through protein kinase C delta

C. Bolm, B. Lüscher, B. Falkenburger, 2020, BMC biology.

ARTD10/PARP10 Induces ADP-Ribosylation of GAPDH and Recruits GAPDH into Cytosolic Membrane-Free Cell Bodies When Overexpressed in Mammalian Cells

Maria Di Girolamo, Emilia Mayo, Gaia Fabrizio, 2018 .

The CCNY (cyclin Y)-CDK16 kinase complex: a new regulator of autophagy downstream of AMPK

D. Neumann, B. Lüscher, J. Vervoorts, 2020, Autophagy.

Postsynaptic clustering of gamma-aminobutyric acid type A receptors by the gamma3 subunit in vivo.

J. Benson, H. Bluethmann, J. Fritschy, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Rescue of γ2 subunit‐deficient mice by transgenic overexpression of the GABAA receptor γ2S or γ2L subunit isoforms

R. Harris, M. Wick, J. Fritschy, 2000 .

Rescue of gamma2 subunit-deficient mice by transgenic overexpression of the GABAA receptor gamma2S or gamma2L subunit isoforms.

R. Harris, M. Wick, J. Fritschy, 2000, The European journal of neuroscience.

Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l

I. Costa, S. Koschmieder, B. Lüscher, 2019, Scientific Reports.

Molecular Simulation-Based Structural Prediction of Protein Complexes in Mass Spectrometry: The Human Insulin Dimer

Jinyu Li, Paolo Carloni, Simone Raugei, 2014, PLoS Comput. Biol..

Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation

B. Lüscher, Karla L. H. Feijs, Alexandra H. Forst, 2013, Nature Reviews Molecular Cell Biology.

Heterogeneity of GABAA-receptors: cell-specific expression, pharmacology, and regulation

J. Paysan, J. Fritschy, H. Mohler, 1995, Neurochemical Research.

IκB kinaseα/β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell‐death mediator receptor‐interacting protein kinase 1

T. Luedde, F. Tacke, C. Trautwein, 2016, Hepatology.

Caspase‐dependent cleavage of the mono‐ADP‐ribosyltransferase ARTD10 interferes with its pro‐apoptotic function

E. Kremmer, B. Lüscher, Henning Kleine, 2013, The FEBS Journal.

AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy

S. Geley, D. Neumann, D. Chanda, 2020, Nature Communications.

Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

D. Litchfield, B. Lüscher, M. Hottiger, 2008, Molecular cell.

Regulation of gene transcription by the oncoprotein MYC.

B. Lüscher, J. Vervoorts, 2012, Gene.

Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10

E. Kremmer, B. Lüscher, Henning Kleine, 2013, Nature Communications.

The 2 Subunit of GABAA Receptors Is a Substrate for Palmitoylation by GODZ

C. Keller, M. Sassoè-Pognetto, M. Alldred, 2004 .

Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors.

B. Lüscher, A. Fallarero, L. Lehtiö, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1.

E. Kremmer, T. Höller, R. Büttner, 2010, Human pathology.

Distinct (cid:1) 2 Subunit Domains Mediate Clustering and Synaptic Function of Postsynaptic GABA A Receptors and Gephyrin

M. Alldred, B. Lüscher, Gong Chen, 2005 .

Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.

L. Ratner, C. Robson, M. Henriksson, 2015, Virology.

Cytokines and inflammation.

G. Müller-Newen, J. Floege, B. Lüscher, 2012, European journal of cell biology.