J. Verhaagen

发表

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons

H. MacGillavry, Jelmer Willems, A. D. de Jong, 2020, PLoS biology.

Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

F. Sablitzky, C. Levelt, S. Niclou, 2004, BMC Neuroscience.

Alteration of the microRNA network during the progression of Alzheimer's disease

Aikaterini S. Papadopoulou, B. de Strooper, S. Aerts, 2013, EMBO molecular medicine.

Modeling early Parkinson's disease pathology with chronic low dose MPTP treatment.

D. Swaab, J. Verhaagen, R. Eggers, 2013, Restorative neurology and neuroscience.

The Effects of Sindbis Viral Vectors on Neuronal Function

A. Smit, K. Li, J. Verhaagen, 2019, Front. Cell. Neurosci..

Analysis of Gene Expression in Parkinson's Disease: Possible Involvement of Neurotrophic Support and Axon Guidance in Dopaminergic Cell Death

C. Kruse, D. Swaab, J. Verhaagen, 2009, Brain pathology.

Cerebellar plasticity and associative memories are controlled by perineuronal nets

Cathrin B. Canto, C. D. De Zeeuw, H. Boele, 2019, Proceedings of the National Academy of Sciences.

Adenoviral Vector-Mediated Expression of B-50/GAP-43 Induces Alterations in the Membrane Organization of Olfactory Axon TerminalsIn Vivo

A. Holtmaat, M. Kaplitt, W. Gispen, 1997, The Journal of Neuroscience.

Expression of a Mutant SEMA3A Protein with Diminished Signalling Capacity Does Not Alter ALS-Related Motor Decline, or Confer Changes in NMJ Plasticity after BotoxA-Induced Paralysis of Male Gastrocnemic Muscle

F. de Winter, J. Verhaagen, B. Hobo, 2017, PloS one.

Timed GDNF gene therapy using an immune-evasive gene switch promotes long distance axon regeneration

M. Malessy, F. de Winter, J. Verhaagen, 2019, Brain : a journal of neurology.

Human Neuroma-in-Continuity Contains Focal Deficits in Myelination

M. Malessy, F. de Winter, J. Verhaagen, 2015, Journal of neuropathology and experimental neurology.

Phenotypic Characterization of Retinoic Acid Differentiated SH-SY5Y Cells by Transcriptional Profiling

Dick F. Swaab, Eva Blaas, August B. Smit, 2013, PloS one.

Identification of candidate transcriptional modulators involved in successful regeneration after nerve injury

A. Smit, N. Armstrong, M. D. de Gunst, 2007, The European journal of neuroscience.

Negative impact of rAAV2 mediated expression of SOCS3 on the regeneration of adult retinal ganglion cell axons

A. Harvey, E. Ehlert, M. Hellström, 2011, Molecular and Cellular Neuroscience.

Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease

P. Dijkhuizen, D. Swaab, J. Verhaagen, 1996, Neuroscience.

Neuroplasticity in the olfactory system: Differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B‐50/GAP43 and the olfactory marker protein

Y. Khew-Goodall, W. Gispen, J. Verhaagen, 1990, Journal of neuroscience research.

A Multilevel Screening Strategy Defines a Molecular Fingerprint of Proregenerative Olfactory Ensheathing Cells and Identifies SCARB2, a Protein That Improves Regenerative Sprouting of Injured Sensory Spinal Axons

A. Smit, R. van Kesteren, J. Verhaagen, 2013, The Journal of Neuroscience.

Upregulation of B50/GAP‐43 protein mRNA in rat dorsal root ganglia during cisplatin intoxication

J. Verhaagen, F. Hamers, J. Neijt, 1996, Journal of neuroscience research.

Viral vector-mediated gene transfer in the nervous system: application to the reconstruction of neural circuits in the injured mammalian brain

A. Holtmaat, M. Kaplitt, W. Gispen, 1995 .

The expression of B-50/GAP-43 in Schwann cells is upregulated in degenerating peripheral nerve stumps following nerve injury

E. Hol, W. Gispen, J. Verhaagen, 1993, Brain Research.

Light- and electron-microscopical study of phosphoprotein B-50 following denervation and reinnervation of the rat soleus muscle

W. Gispen, J. Verhaagen, F. Jennekens, 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains*

J. Fawcett, L. Hsieh‐Wilson, E. Ehlert, 2013, The Journal of Biological Chemistry.

Early molecular changes in Alzheimer disease: can we catch the disease in its presymptomatic phase?

D. Swaab, J. Verhaagen, K. Bossers, 2013, Journal of Alzheimer's disease : JAD.

Lentiviral Vector-Mediated Gradients of GDNF in the Injured Peripheral Nerve: Effects on Nerve Coil Formation, Schwann Cell Maturation and Myelination

M. Malessy, E. Ehlert, F. de Winter, 2013, PloS one.

Differential effects of lentiviral vector‐mediated overexpression of nerve growth factor and glial cell line‐derived neurotrophic factor on regenerating sensory and motor axons in the transected peripheral nerve

M. Malessy, G. D. de Ruiter, J. Verhaagen, 2008, The European journal of neuroscience.

Evaluation of five tests for the assessment of functional recovery following C 4 or T 7 dorsal column transection in the rat

J. Verhaagen, R. Eggers, N. Fagoe, 2014 .

Expression of the growth-associated protein B-50/GAP43 via a defective herpes-simplex virus vector results in profound morphological changes in non-neuronal cells.

D. Pfaff, S. Rabkin, M. Kaplitt, 1994, Brain research. Molecular brain research.

Gene delivery to rat and human Schwann cells and nerve segments: a comparison of AAV 1–9 and lentiviral vectors

M. Malessy, J. Verhaagen, M. Tannemaat, 2015, Gene Therapy.

Cellular tropism and transduction properties of seven adeno-associated viral vector serotypes in adult retina after intravitreal injection

A. Harvey, M. Ruitenberg, E. Ehlert, 2009, Gene Therapy.

The effect of ACTH4–10 on protein synthesis, actin and tubulin during regeneration

J. Verhaagen, F. Jennekens, P. Schotman, 1985, Brain Research Bulletin.

Suppression of inflammation by dexamethasone prolongs adenoviral vector-mediated transgene expression in the facial nucleus of the rat

J. Verhaagen, W. Hermens, 1998, Brain Research Bulletin.

Adenoviral vector-mediated gene expression in the nervous system of immunocompetent Wistar and T cell-deficient nude rats: preferential survival of transduced astroglial cells in nude rats.

J. Verhaagen, W. Hermens, Joost Verhaagen, 1997, Human gene therapy.

Coordinated changes in the expression of Wnt pathway genes following human and rat peripheral nerve injury

M. Malessy, L. Fradkin, F. de Winter, 2021, PloS one.

ATF 3 promotes regeneration of the central axon branch of sensory neurons but the addition of Smad 1 , c-Jun and STAT 3 does not exert synergistic effects

J. Verhaagen, N. Fagoe, C. L. Attwell, 2014 .

Transplantation of the rat suprachiasmatic nucleus . Functional studies and ex vivo adenoviral vector-mediated gene transfer

Boer, P. Dijkhuizen, J. Verhaagen, 2012 .

Portal Semaphorin 3 A in injury and disease : its role at the neuromuscular junction

J. Verhaagen, B. Hobo, E. Moloney, 2022 .

Olfactory ensheathing glia and Schwann cells exhibit a distinct interaction behavior with meningeal cells

J. Verhaagen, F. D. de Bree, Elske H. P. Franssen, 2009, Journal of neuroscience research.

A comparison of selected mRNA and protein abundances of target genes involved in Alzheimer’s disease development

D. Swaab, J. Verhaagen, K. Bossers, 2013 .

CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease

M. Mielke, H. D. de Vries, J. Walter, 2020, Alzheimer's research & therapy.

B‐50/GAP43 Gene Expression in the Rat Olfactory System During Postnatal Development and Aging

C. Greer, J. Verhaagen, F. Margolis, 1990, The European journal of neuroscience.

Expression of growth-associated protein B-50 (GAP43) in dorsal root ganglia and sciatic nerve during regenerative sprouting

W. Gispen, J. Verhaagen, L. Schrama, 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells

J. Verhaagen, R. Eggers, G. Boer, 2007, Journal of neuroscience research.

Adenoviral vector-mediated gene transfer and neurotransplantation: possibilities and limitations in grafting of the fetal rat suprachiasmatic nucleus

J. Verhaagen, W. Hermens, G. Boer, 1997, Journal of Neuroscience Methods.

Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death1

E. Hol, D. Goldgaber, J. Verhaagen, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Viral vectors, tools for gene transfer in the nervous system

J. Verhaagen, W. Hermens, 1998, Progress in Neurobiology.

Sema3A regulates the timing of target contact by cranial sensory axons

J. Verhaagen, R. Giger, M. Rochlin, 2004, The Journal of comparative neurology.

Comparison of neurotrophin and repellent sensitivities of early embryonic geniculate and trigeminal axons

A. Farbman, J. Verhaagen, R. Giger, 2000, The Journal of comparative neurology.

Ontogeny of neurotrophin receptor TrkC expression in the rat forebrain and anterior hypothalamus with emphasis on the suprachiasmatic nucleus

P. Dijkhuizen, J. Verhaagen, G. Boer, 1999, Neuroscience.

Differential myofiber-type transduction preference of adeno-associated virus serotypes 6 and 9

J. Verhaagen, S. M. van der Maarel, Y. Raz, 2015, Skeletal Muscle.

Chondroitin sulfate proteoglycans prevent immune cell phenotypic conversion and inflammation resolution via TLR4 in rodent models of spinal cord injury

V. Moreno-Manzano, F. de Winter, J. Verhaagen, 2022, Nature Communications.

A Gene Network Perspective on Axonal Regeneration

A. Smit, R. van Kesteren, H. MacGillavry, 2011, Front. Mol. Neurosci..

Inhibition of Semaphorin-3A promotes ocular dominance plasticity in the adult rat visual cortex

J. Fawcett, T. Pizzorusso, E. Boggio, 2018 .

Transient gene transfer to neurons and glia: Analysis of adenoviral vector performance in the CNS and PNS

A. Holtmaat, P. Dijkhuizen, J. Verhaagen, 1997, Journal of Neuroscience Methods.

Gene delivery to neurons of the dorsal root ganglia using adeno-associated viral vectors.

J. Verhaagen, R. Eggers, N. Fagoe, 2015 .

Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: Comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors

E. Ehlert, J. Verhaagen, J. Twisk, 2010, Journal of Neuroscience Methods.

GENETIC MODIFICATION OF HUMAN SURAL NERVE SEGMENTS BY A LENTIVIRAL VECTOR ENCODING NERVE GROWTH FACTOR

M. Malessy, J. Verhaagen, M. Tannemaat, 2007, Neurosurgery.

Long-Term Adeno-Associated Viral Vector-Mediated Expression of Truncated TrkB in the Adult Rat Facial Nucleus Results in Motor Neuron Degeneration

E. Castrén, R. Evers, J. Verhaagen, 2006, The Journal of Neuroscience.

Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system.

P. Dijkhuizen, D. Grimm, J. Kleinschmidt, 1999, Human gene therapy.

Human Neuroma Contains Increased Levels of Semaphorin 3A, Which Surrounds Nerve Fibers and Reduces Neurite Extension In Vitro

M. Malessy, E. Ehlert, J. Verhaagen, 2007, The Journal of Neuroscience.

Upregulation of B-50/GAP-43 in Schwann cells at denervated motor endplates and in motoneurons after rat facial nerve crush.

M. Mercken, W. Gispen, J. Verhaagen, 1993, Restorative neurology and neuroscience.

Regeneration of adult rat sensory and motor neuron axons through chimeric peroneal nerve grafts containing donor Schwann cells engineered to express different neurotrophic factors

A. Harvey, M. J. Godinho, G. Plant, 2020, Experimental Neurology.

Adenoviral vector-mediated gene delivery to injured rat peripheral nerve.

P. Dijkhuizen, F. de Winter, J. Verhaagen, 1998, Journal of neurotrauma.

Adenoviral vector-directed expression of neurotrophin-3 in rat dorsal root ganglion explants results in a robust neurite outgrowth response.

P. Dijkhuizen, J. Verhaagen, W. Hermens, 1997, Journal of neurobiology.

B-50/GAP-43 in neuronal development and repair.

J. Boonstra, W. Gispen, J. Verhaagen, 1990, Restorative neurology and neuroscience.

Mechanisms of intermittent hypoxia-induced functional recovery after spinal cord injury

J. Fawcett, D. Chew, R. Fässler, 2014 .

Effective use of a neurotrophic ACTH4-9 analogue in the treatment of a peripheral demyelinating syndrome (experimental allergic neuritis). An intervention study.

W. Gispen, J. Verhaagen, E. D. de Bruijn, 1994, Brain : a journal of neurology.

A Role for Neuropilins in the Interaction between Schwann Cells and Meningeal Cells

J. Verhaagen, Elske H. P. Franssen, K. Wirz, 2014, PloS one.

Evidence that the neurotrophic actions of α-MSH may derive from its ability to mimick the actions of a peptide formed in degenerating nerve stumps

W. Gispen, J. Verhaagen, F. Jennekens, 1984, Journal of the Neurological Sciences.

CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease

M. Mielke, H. D. de Vries, J. Walter, 2020, Alzheimer's Research & Therapy.

General introduction Understanding the neural repair- promoting properties of olfactory ensheathing cells

J. Verhaagen, K. Roet, 2011 .

Adenoviral Vector-Mediated Expression of a Foreign Gene in Peripheral Nerve Tissue Bridges Implanted in the Injured Peripheral and Central Nervous System

T. Carlstedt, P. Dijkhuizen, J. Verhaagen, 1999, Experimental Neurology.

Lentiviral vector-mediated reporter gene expression in avulsed spinal ventral root is short-term, but is prolonged using an immune "stealth" transgene.

T. Carlstedt, J. Verhaagen, R. Eggers, 2007, Restorative neurology and neuroscience.

Schwann cells transduced with a lentiviral vector encoding Fgf‐2 promote motor neuron regeneration following sciatic nerve injury

X. Navarro, I. Allodi, E. Udina, 2014, Glia.

The Jun-dependent axon regeneration gene program: Jun promotes regeneration over plasticity

A. Behrens, J. Verhaagen, G. Raivich, 2021, Human molecular genetics.

Intrinsic Determinants of Axon Regeneration

J. Fawcett, J. Verhaagen, 2018, Developmental neurobiology.

Early regenerative effects of NGF-transduced Schwann cells in peripheral nerve repair

R. Midha, A. Shakhbazau, J. Verhaagen, 2012, Molecular and Cellular Neuroscience.

The Use of Adenoviral Vectors and Ex Vivo Transduced Neurotransplants: Towards Promotion of Neuroregeneration

P. Dijkhuizen, J. Verhaagen, W. Hermens, 2000, Cell transplantation.

Transgene expression in rat fetal brain grafts is maintained for 7 months after ex vivo adenoviral vector-mediated gene transfer

J. Verhaagen, W. Hermens, G. Boer, 1998, Neuroscience Letters.

The Expression of B‐50/GAP‐43 in Schwann Cells

W. Gispen, J. Verhaagen, L. Plantinga, 1993, Annals of the New York Academy of Sciences.

Pharmacological evidence for the involvement of endogenous α-MSH-like peptides in peripheral nerve regeneration

W. Gispen, J. Verhaagen, J. Brakkee, 1995, Peptides.

Characterization of an immune-evading doxycycline-inducible lentiviral vector for gene therapy in the spinal cord

J. Verhaagen, R. Eggers, B. Hobo, 2022, Experimental Neurology.

A spatio-temporal analysis of motoneuron survival, axonal regeneration and neurotrophic factor expression after lumbar ventral root avulsion and implantation

E. Ehlert, J. Verhaagen, R. Eggers, 2010, Experimental Neurology.

Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries

J. Fawcett, J. Verhaagen, J. Kwok, 2020, Scientific Reports.

α-Melanocyte-stimulating hormone stimulates the outgrowth of myelinated nerve fibers after peripheral nerve crush

W. Gispen, J. Verhaagen, F. Jennekens, 1986, Experimental Neurology.

Early passage bone marrow stromal cells express genes involved in nervous system development supporting their relevance for neural repair.

J. Grotenhuis, M. Oudega, J. Verhaagen, 2011, Restorative neurology and neuroscience.

Neurotherapy: Progress in Restorative Neuroscience and Neurology. Preface.

J. Verhaagen, 2009, Progress in brain research.

Large-Scale Chondroitin Sulfate Proteoglycan Digestion with Chondroitinase Gene Therapy Leads to Reduced Pathology and Modulates Macrophage Phenotype following Spinal Cord Contusion Injury

Rafael J. Yáñez-Muñoz, A. Didangelos, J. Verhaagen, 2014, The Journal of Neuroscience.

Combining timed GDNF and ChABC gene therapy to promote long‐distance regeneration following ventral root avulsion and repair

J. Verhaagen, R. Eggers, M. Tannemaat, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Enhanced regeneration and reinnervation following timed GDNF gene therapy in a cervical ventral root avulsion

F. de Winter, J. Verhaagen, R. Eggers, 2019, Experimental Neurology.

Use of GFP to analyze morphology, connectivity, and function of cells in the central nervous system.

A. Harvey, C. Levelt, E. Drummond, 2009, Methods in molecular biology.

Restoring the pattern of proteoglycan sulphation in perineuronal nets corrects age-related memory loss

J. Fawcett, L. Saksida, H. Kitagawa, 2020, bioRxiv.

Restoring the pattern of perineuronal net sulphation corrects age-related memory loss

J. Fawcett, L. Saksida, H. Kitagawa, 2020 .

1 General introduction. Nerve surgery and gene therapy: a neurobiological and clinical perspective

M. Malessy, J. Verhaagen, M. Tannemaat, 2016 .

CHAPTER 8 General discussion

D. Swaab, J. Verhaagen, R. E. Kesteren, 2012 .

B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system

W. Gispen, J. Verhaagen, L. Schrama, 1997, Progress in Neurobiology.

Resolution of Rat Brain Synaptic Phosphoprotein B‐50 into Multiple Forms by Two‐Dimensional Electrophoresis: Evidence for Multisite Phosphorylation

W. Gispen, J. Verhaagen, C. J. Dongen, 1985, Journal of neurochemistry.

ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease

F. de Winter, J. Verhaagen, E. Moloney, 2014, Front. Neurosci..

On the neurotrophic action of melanocortins.

W. Gispen, J. Verhaagen, C. Van der Zee, 1987, Progress in brain research.

Characterization of epitopes shared by α‐melanocyte‐stimulating hormone (α‐MSH) and the 150‐kd neurofilament protein (NF150): Relationship to neurotrophic sequences

J. Verhaagen, P. Schotman, P. M. Edwards, 1986, Journal of neuroscience research.

B‐50/GAP43 Expression Correlates with Process Outgrowth in the Embryonic Mouse Nervous System

S. Biffo, J. Verhaagen, L. Schrama, 1990, The European journal of neuroscience.

The kinase C substrate protein B-50 (GAP43) and its function in axonal repair mechanisms

W. Gispen, J. Verhaagen, C. V. Hooff, 1988 .

The kinase c substrate protein b-50 and axonal regeneration

W. Gispen, J. Verhaagen, F. Jennekens, 1986, Brain Research Bulletin.

Immunolocalization of B-50 (GAP-43) in the mouse olfactory bulb: Predominant presence in preterminal axons

W. Gispen, J. Verhaagen, F. Margolis, 1992, Journal of neurocytology.

Regulation of gene expression in the olfactory neuroepithelium: a neurogenetic matrix.

F. Huang, S. Biffo, J. Verhaagen, 1991, Progress in brain research.

The expression of the growth associated protein B50/GAP43 in the olfactory system of neonatal and adult rats

J. Verhaagen, F. Margolis, W. Gispen, 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

The role of the neural growth associated protein B-50/GAP-43 in morphogenesis.

W. Gispen, J. Verhaagen, L. Schrama, 1998, Advances in experimental medicine and biology.

Gene therapy approaches to enhance regeneration of the injured peripheral nerve.

M. Malessy, F. de Winter, J. Verhaagen, 2013, European journal of pharmacology.

Org.2766 stimulates collateral sprouting in the soleus muscle of the rat following partial denervation

J. Verhaagen, F. Jennekens, W. Sloot, 1989, Muscle & nerve.

Proteomics of the Injured Rat Sciatic Nerve Reveals Protein Expression Dynamics During Regeneration *

A. Smit, F. J. Stam, K. Li, 2005, Molecular & Cellular Proteomics.

Gene Delivery and Therapy for Neurological Disorders

J. Verhaagen, X. Bo, 2015, Neuromethods.

A novel peptidomics approach to detect markers of Alzheimer's disease in cerebrospinal fluid.

L. McDonnell, D. Swaab, D. Wijte, 2012, Methods.

Expression of the Gene Encoding the Chemorepellent Semaphorin III Is Induced in the Fibroblast Component of Neural Scar Tissue Formed Following Injuries of Adult But Not Neonatal CNS

M. Ruitenberg, J. D. Wit, J. Verhaagen, 1999, Molecular and Cellular Neuroscience.

ACTH and signal transduction in the neuronal membrane

W. Gispen, J. Verhaagen, V. Wiegant, 1986 .

ACTH/MSH-derived peptides and peripheral nerve plasticity: neuropathies, neuroprotection and repair.

W. Gispen, J. Verhaagen, D. Bär, 1994, Progress in brain research.

The neurotrophic analogue of ACTH(4-9), Org 2766, protects against experimental allergic neuritis.

W. Gispen, J. Verhaagen, H. Duckers, 1993, Brain : a journal of neurology.

alpha MSH but not Org 2766 induces expression of c-fos in cultured rat spinal cord cells.

E. Hol, W. Gispen, J. Verhaagen, 1993, Neuroreport.

Early effect of an ACTH4–9 analog (Org. 2766) on regenerative sprouting demonstrated by the use of neurofilament-binding antibodies isolated from a serum raised by α-MSH immunization

W. Gispen, J. Verhaagen, P. Schotman, 1987, Brain Research.

Targeted Overexpression of the Neurite Growth-Associated Protein B-50/GAP-43 in Cerebellar Purkinje Cells Induces Sprouting after Axotomy But Not Axon Regeneration into Growth-Permissive Transplants

A. Holtmaat, P. Strata, F. Rossi, 1997, The Journal of Neuroscience.

Continuous renewal of the axonal pathway sensor apparatus by insertion of new sensor molecules into the growth cone membrane

D. Pfaff, P. Sonderegger, M. Kaplitt, 1996, Current Biology.

Transgenic expression of B-50/GAP-43 in mature olfactory neurons triggers downregulation of native B-50/GAP-43 expression in immature olfactory neurons.

A. Holtmaat, W. Gispen, J. Verhaagen, 1999, Brain research. Molecular brain research.

Efficient adenoviral vector-directed expression of a foreign gene to neurons and sustentacular cells in the mouse olfactory neuroepithelium.

A. Holtmaat, M. Kaplitt, W. Gispen, 1996, Brain research. Molecular brain research.

Brain Endothelial Cells Control Fertility through Ovarian-Steroid–Dependent Release of Semaphorin 3A

S. Bouret, A. Messina, M. Mazzone, 2014, PLoS biology.

Neurotrophic ACTH4–9 analogue therapy normalizes electroencephalographic alterations in chronic experimental allergic encephalomyelitis

F. D. da Silva, E. van Luijtelaar, A. Coenen, 1998, The European journal of neuroscience.

Gene therapy and peripheral nerve repair: a perspective

M. Malessy, F. de Winter, J. Verhaagen, 2015, Front. Mol. Neurosci..

Functional and neurophysiological evidence of the efficacy of trophic pharmacotherapy using an adrenocorticotrophic hormone4–9 analog in experimental allergic encephalomyelitis, an animal model of multiple sclerosis

W. Gispen, J. Verhaagen, H. Duckers, 1996, Neuroscience.

Proteoglycans as modulators of axon guidance cue function.

J. Verhaagen, Joris de Wit, 2007, Advances in experimental medicine and biology.

Semaphorins in axon regeneration: developmental guidance molecules gone wrong?

J. Verhaagen, R. Pasterkamp, R. Jeroen Pasterkamp, 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

Role of semaphorins in the adult nervous system

J. D. Wit, J. Verhaagen, 2003, Progress in Neurobiology.

Neuropilin and class 3 semaphorins in nervous system regeneration.

A. Holtmaat, F. de Winter, J. Verhaagen, 2002, Advances in experimental medicine and biology.

Wnt Signaling through the Ror Receptor in the Nervous System

M. Malessy, L. Fradkin, J. Verhaagen, 2013, Molecular Neurobiology.

Chondroitinase ABC promotes plasticity of spinal reflexes following peripheral nerve injury

J. Fawcett, S. McMahon, J. Verhaagen, 2012, Experimental Neurology.

Manipulation of gene expression in the mammalian nervous system: application in the study of neurite outgrowth and neuroregeneration-related proteins

A. Holtmaat, W. Gispen, J. Verhaagen, 1998, Brain Research Reviews.

Overexpression of ATF3 or the combination of ATF3, c-Jun, STAT3 and Smad1 promotes regeneration of the central axon branch of sensory neurons but without synergistic effects.

J. Verhaagen, N. Fagoe, C. L. Attwell, 2015, Human molecular genetics.

The application of viral vectors to enhance regeneration after peripheral nerve repair

M. Malessy, J. Verhaagen, M. Tannemaat, 2008, Neurological research.

The glycoprotein fibulin‐3 regulates morphology and motility of olfactory ensheathing cells in vitro

A. Harvey, Takako Sasaki, S. Busfield, 2009, Glia.

Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

Rafael J. Yáñez-Muñoz, J. Verhaagen, T. Hutson, 2011, Gene Therapy.

In vivo targeting of subventricular zone astrocytes

E. Hol, J. Verhaagen, Carlyn Mamber, 2010, Progress in Neurobiology.

Overexpression of a truncated TrkB isoform increases the proliferation of neural progenitors

E. Castrén, T. Tervonen, F. Ajamian, 2006, The European journal of neuroscience.

Viral vector-mediated gene transfer of neurotrophins to promote regeneration of the injured spinal cord.

M. Ruitenberg, J. Verhaagen, G. Boer, 2004, Progress in brain research.

Molecular Changes in the Dorsal Root Ganglion during the Late Phase of Peripheral Nerve Injury–induced Pain in Rodents: A Systematic Review

A. Dahan, M. Malessy, J. Verhaagen, 2021, Anesthesiology.

Gene Therapy for Spinal Cord Injury

M. Ruitenberg, J. Verhaagen, G. Boer, 2006 .

Ex Vivo Adenoviral Vector-Mediated Neurotrophin Gene Transfer to Olfactory Ensheathing Glia: Effects on Rubrospinal Tract Regeneration, Lesion Size, and Functional Recovery after Implantation in the Injured Rat Spinal Cord

P. Dijkhuizen, M. Ruitenberg, W. Gispen, 2003, The Journal of Neuroscience.

Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord

A. Harvey, S. Niclou, M. Ruitenberg, 2002, Gene Therapy.

Long-Term Transgene Expression in Fetal Rat Suprachiasmatic Nucleus Neurografts Followingex VivoAdenoviral Vector-Mediated Gene Transfer

J. Verhaagen, W. Hermens, G. Boer, 1997, Experimental Neurology.

Homodimerization of the Wnt Receptor DERAILED Recruits the Src Family Kinase SRC64B

M. Malessy, L. Fradkin, J. Verhaagen, 2013, Molecular and Cellular Biology.

Evidence for a Role of the Chemorepellent Semaphorin III and Its Receptor Neuropilin-1 in the Regeneration of Primary Olfactory Axons

A. Holtmaat, F. de Winter, J. Verhaagen, 1998, The Journal of Neuroscience.

Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system

S. Niclou, E. Ehlert, J. Verhaagen, 2010, BMC Neuroscience.

Anti-inflammatory effect by lentiviral-mediated overexpression of IL-10 or IL-1 receptor antagonist in rat glial cells and macrophages

J. Bol, J. Verhaagen, S. Poole, 2010, Gene Therapy.

Chemorepellent axon guidance molecules in spinal cord injury.

S. Niclou, E. Ehlert, J. Verhaagen, 2006, Journal of neurotrauma.

Semaphorin 3A displays a punctate distribution on the surface of neuronal cells and interacts with proteoglycans in the extracellular matrix

J. Klooster, J. D. Wit, J. Verhaagen, 2005, Molecular and Cellular Neuroscience.

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain.

E. Hol, A. Vescovi, W. V. D. van de Berg, 2011, Brain : a journal of neurology.

Spinal Cord Injury and the Neuron-Intrinsic Regeneration-Associated Gene Program

J. Verhaagen, N. Fagoe, Jessica van Heest, 2014, NeuroMolecular Medicine.

General introduction : Spinal cord injury and the neuron-intrinsic regeneration-associated gene program And : Aim and scope of this thesis

J. Verhaagen, N. Fagoe, M. Mason, 2014 .

The cell biology of olfaction

A. Farbman, J. Verhaagen, 1992 .

Olfactory ensheathing glia: Their contribution to primary olfactory nervous system regeneration and their regenerative potential following transplantation into the injured spinal cord

J. Verhaagen, Elske H. P. Franssen, F. Bree, 2007, Brain Research Reviews.

Understanding the neural repair-promoting properties of olfactory ensheathing cells

J. Verhaagen, K. Roet, 2012, Experimental Neurology.

Clinical and neurobiological advances in promoting regeneration of the ventral root avulsion lesion

M. Malessy, F. de Winter, J. Verhaagen, 2016, The European journal of neuroscience.

Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord

J. Fawcett, D. Chew, R. Fässler, 2016, The Journal of Neuroscience.

P75 Neurotrophin Receptor in the Nucleus Basalis of Meynert in Relation to Age, Sex, and Alzheimer's Disease

D. Swaab, J. Verhaagen, A. Salehi, 2000, Experimental Neurology.

Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease.

C. Kruse, D. Swaab, J. Verhaagen, 2010, Brain : a journal of neurology.

A comparative morphological, electrophysiological and functional analysis of axon regeneration through peripheral nerve autografts genetically modified to overexpress BDNF, CNTF, GDNF, NGF, NT3 or VEGF

M. Malessy, J. Verhaagen, L. Boon, 2014, Experimental Neurology.

Growth of pyramidal, but not non‐pyramidal, dendrites in long‐term organotypic explants of neonatal rat neocortex chronically exposed to neurotrophin‐3

J. van Pelt, J. Pelt, P. Dijkhuizen, 1998, The European journal of neuroscience.

Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor

T. Carlstedt, P. Dijkhuizen, L. Tenenbaum, 2004, Experimental Neurology.

Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa.

J. Flannery, S. Beck, Marina Garcia Garrido, 2014, Human molecular genetics.

The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease

S. Niclou, F. J. Stam, J. Verhaagen, 2006, Molecular and Cellular Neuroscience.

Gene therapy and transplantation in CNS repair: The visual system

A. Harvey, G. Plant, J. Verhaagen, 2006, Progress in Retinal and Eye Research.

GDNF Gene Therapy to Repair the Injured Peripheral Nerve

M. Malessy, F. de Winter, J. Verhaagen, 2020, Frontiers in Bioengineering and Biotechnology.

Neuroregenerative effects of lentiviral vector-mediated GDNF expression in reimplanted ventral roots

T. Carlstedt, J. Verhaagen, R. Eggers, 2008, Molecular and Cellular Neuroscience.

Evaluation of Five Tests for Sensitivity to Functional Deficits following Cervical or Thoracic Dorsal Column Transection in the Rat

J. Verhaagen, R. Eggers, N. Fagoe, 2016, PloS one.

Combinatorial overexpression of regeneration-associated transcription factors in medium-throughput cellular screens for neurite outgrowth

A. Smit, J. Verhaagen, R. E. Kesteren, 2014 .

NFIL3 and cAMP Response Element-Binding Protein Form a Transcriptional Feedforward Loop that Controls Neuronal Regeneration-Associated Gene Expression

A. Smit, R. van Kesteren, F. J. Stam, 2009, The Journal of Neuroscience.

Lentiviral-mediated expression of polysialic acid in spinal cord and conditioning lesion promote regeneration of sensory axons into spinal cord.

J. Verhaagen, P. Richardson, X. Bo, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Peripheral nerve injury fails to induce growth of lesioned ascending dorsal column axons into spinal cord scar tissue expressing the axon repellent Semaphorin3A

J. Verhaagen, R. Pasterkamp, Patrick N. Anderson, 2001, The European journal of neuroscience.

Anatomy of rat semaphorin III collapsin‐1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis

D. Wolfer, J. Verhaagen, R. Giger, 1996 .

NT‐3 delivered by an adenoviral vector induces injured dorsal root axons to regenerate into the spinal cord of adult rats

P. Dijkhuizen, Yi Zhang, J. Verhaagen, 1998, Journal of neuroscience research.

Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo

A. Smit, R. van Kesteren, E. Ehlert, 2015, PloS one.

Genome-wide gene expression and promoter binding analysis identifies NFIL3 as a repressor of C/EBP target genes in neuronal outgrowth

August B. Smit, Ronald E. van Kesteren, A. Smit, 2011, Molecular and Cellular Neuroscience.

Expression of the pro-opiomelanocortin gene in dorsal root ganglia, spinal cord and sciatic nerve after sciatic nerve crush in the rat.

J. Burbach, W. Gispen, J. Verhaagen, 1992, Brain research. Molecular brain research.

Developing a potentially immunologically inert tetracycline-regulatable viral vector for gene therapy in the peripheral nerve

J. Verhaagen, R. Eggers, T. Ozawa, 2014, Gene Therapy.

Sulfatase‐mediated manipulation of the astrocyte‐Schwann cell interface

J. Riddell, J. Turnbull, S. Barnett, 2016, Glia.

A perspective on the role of class III semaphorin signaling in central nervous system trauma

J. Verhaagen, Vasilis Mecollari, Bart Nieuwenhuis, 2014, Front. Cell. Neurosci..

Reply: Quantitative evaluation of the human subventricular zone

E. Hol, A. Vescovi, J. Verhaagen, 2012 .

Anatomy of rat semaphorin III/collapsin-1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis.

D. Wolfer, J. Verhaagen, R. Giger, 1996, The Journal of comparative neurology.

The Effect of Inflammatory Priming on the Therapeutic Potential of Mesenchymal Stromal Cells for Spinal Cord Repair

M. Oudega, J. Verhaagen, Ines Maldonado-Lasunción, 2021, Cells.

Macrophage-Derived Inflammation Induces a Transcriptome Makeover in Mesenchymal Stromal Cells Enhancing Their Potential for Tissue Repair

M. Oudega, J. Verhaagen, Ines Maldonado-Lasunción, 2021, International journal of molecular sciences.

Mesenchymal Stem Cell-Macrophage Choreography Supporting Spinal Cord Repair

M. Oudega, J. Verhaagen, Ines Maldonado-Lasunción, 2018, Neurotherapeutics.

Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries

J. Fawcett, J. Verhaagen, J. Kwok, 2020, Scientific Reports.

Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons

Rafael J. Yáñez-Muñoz, J. Fawcett, R. Keynes, 2011, Journal of Neuroscience Methods.

GFAP-Driven GFP Expression in Activated Mouse Müller Glial Cells Aligning Retinal Blood Vessels Following Intravitreal Injection of AAV2/6 Vectors

J. Wijnholds, R. Ali, E. Ehlert, 2010, PloS one.

Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo.

A. Holtmaat, P. Emson, J. Verhaagen, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Lentiviral-mediated transfer of CNTF to schwann cells within reconstructed peripheral nerve grafts enhances adult retinal ganglion cell survival and axonal regeneration.

Qi Cui, Simone P Niclou, Alan R Harvey, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

A meta-analysis of microarray-based gene expression studies of olfactory bulb-derived olfactory ensheathing cells

M. Ruitenberg, J. Verhaagen, K. Bossers, 2011, Experimental Neurology.

From microsurgery to nanosurgery: how viral vectors may help repair the peripheral nerve.

M. Malessy, J. Verhaagen, R. Eggers, 2009, Progress in brain research.

Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex

J. Fawcett, C. V. Vander Kooi, T. Pizzorusso, 2019, Molecular Neurobiology.

Pharmacological, Cell, and Gene Therapy Strategies to Promote Spinal Cord Regeneration

J. Verhaagen, G. Boer, B. Blits, 2002, Cell transplantation.

Transient downregulation of sema3a mrna in a rat model for temporal lobe epilepsy A novel molecular event potentially contributing to mossy fiber sprouting

A. Holtmaat, F. D. Silva, S. Spijker, 2003, Experimental Neurology.

NT-3 expression from engineered olfactory ensheathing glia promotes spinal sparing and regeneration.

A. Harvey, M. Ruitenberg, G. Plant, 2005, Brain : a journal of neurology.

Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer’s disease mouse models

Sebastian Munck, Dick F. Swaab, Julien Colombelli, 2015, Science Translational Medicine.

Cell-replacement and gene-therapy strategies for Parkinson's and Alzheimer's disease.

E. Hol, J. Verhaagen, J. Korecka, 2007, Regenerative medicine.

Microarray and Morphological Analysis of Early Postnatal CRB2 Mutant Retinas on a Pure C57BL/6J Genetic Background

J. Wijnholds, P. J. van der Spek, J. Verhaagen, 2013, PloS one.

Integrins promote axonal regeneration after injury of the nervous system

J. Fawcett, J. Verhaagen, Barbara Haenzi, 2018, Biological reviews of the Cambridge Philosophical Society.

Early growth response‐1 regulates acetylcholinesterase and its relation with the course of Alzheimer’s disease

D. Swaab, J. Verhaagen, Juan Zhao, 2018, Brain pathology.

Brain-derived neurotrophic factor in the ventral midbrain–nucleus accumbens pathway: a role in depression

M. Barrot, E. Nestler, J. D. Wit, 2003, Biological Psychiatry.

Injury-Induced Class 3 Semaphorin Expression in the Rat Spinal Cord

J. Verhaagen, M. Oudega, M. Ruitenberg, 2002, Experimental Neurology.

Semaphorins in Adult Nervous System Plasticity and Disease

F. de Winter, J. Verhaagen, D. Carulli, 2021, Frontiers in Synaptic Neuroscience.

Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters

J. Fawcett, J. Verhaagen, B. Hobo, 2020, Gene Therapy.

Cells in human postmortem brain tissue slices remain alive for several weeks in culture

R. Verwer, P. Dijkhuizen, D. Swaab, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Reversible CD8 T cell–neuron cross-talk causes aging-dependent neuronal regenerative decline

J. Bixby, S. Di Giovanni, F. de Winter, 2022, Science.

Comparison of AAV serotypes for gene delivery to dorsal root ganglion neurons.

E. Ehlert, J. Verhaagen, R. Eggers, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Receptor complexes for each of the Class 3 Semaphorins

A. Harvey, J. Verhaagen, Anil Sharma, 2012, Front. Cell. Neurosci..

Comparative gene expression profiling of olfactory ensheathing glia and Schwann cells indicates distinct tissue repair characteristics of olfactory ensheathing glia

J. Verhaagen, Elske H. P. Franssen, A. Ramón-Cueto, 2008, Glia.

Recent advances in the therapeutic uses of chondroitinase ABC

J. Verhaagen, F. Winter, E. Muir, 2019, Experimental Neurology.

Comparison of AAV Serotypes for Gene Delivery to Dopaminergic Neurons in the Substantia Nigra

J. Verhaagen, M. Schouten, R. Eggers, 2011 .

Chondroitinase gene therapy improves upper limb function following cervical contusion injury

J. Verhaagen, B. Schneider, E. Muir, 2015, Experimental Neurology.

Meningeal cell-derived semaphorin 3A inhibits neurite outgrowth

S. Niclou, E. Ehlert, J. Verhaagen, 2003, Molecular and Cellular Neuroscience.

Emerging roles for semaphorins in neural regeneration

J. Verhaagen, R. Pasterkamp, 2001, Brain Research Reviews.

Nerve surgery and gene therapy: a neurobiological and clinical perspective

M. Malessy, F. de Winter, J. Verhaagen, 2011, The Journal of hand surgery, European volume.

International spinal research trust research strategy. III: A discussion document

G. Raisman, R. Lemon, T. Carlstedt, 2007, Spinal Cord.

Amelioration of chronic neuropathic pain after partial nerve injury by adeno-associated viral (AAV) vector-mediated over-expression of BDNF in the rat spinal cord

M. Oudega, M. Ruitenberg, J. Verhaagen, 2002, Gene Therapy.

Semaphorin III: role in neuronal development and structural plasticity.

A. Holtmaat, J. Verhaagen, R. Giger, 1998, Progress in brain research.

The Chemorepulsive Protein Semaphorin 3A and Perineuronal Net-Mediated Plasticity

J. Fawcett, F. de Winter, J. Verhaagen, 2016, Neural plasticity.

An Extracellular Perspective on CNS Maturation: Perineuronal Nets and the Control of Plasticity

J. Verhaagen, D. Carulli, 2021, International journal of molecular sciences.

Title Targeted ablation of Crb 2 in photoreceptor cells induces retinitis pigmentosa

J. Flannery, S. Beck, Christina Seide, 2014 .

Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury

P. Dijkhuizen, M. Ruitenberg, J. Verhaagen, 2004, Neurobiology of Disease.

Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular fiber growth

P. Dijkhuizen, A. Berns, J. Verhaagen, 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

A compact dual promoter adeno-associated viral vector for efficient delivery of two genes to dorsal root ganglion neurons

J. Verhaagen, R. Eggers, N. Fagoe, 2013, Gene Therapy.

AAV-mediated expression of CNTF promotes long-term survival and regeneration of adult rat retinal ganglion cells

A. Harvey, G. Plant, J. Verhaagen, 2006, Gene Therapy.

Pharmacological aspects of the influence of melanocortins on the formation of regenerative peripheral nerve sprouts

W. Gispen, J. Verhaagen, P. M. Edwards, 1987, Peptides.

Semaphorins: contributors to structural stability of hippocampal networks?

A. Holtmaat, F. D. da Silva, J. Gorter, 2002, Progress in brain research.

Vesicular Trafficking of Semaphorin 3A is Activity‐Dependent and Differs Between Axons and Dendrites

M. Verhage, R. Toonen, J. Verhaagen, 2006, Traffic.

Spinal Cord Injury and the Neuron-Intrinsic Regeneration-Associated Gene Program

J. Verhaagen, N. Fagoe, Jessica van Heest, 2014, NeuroMolecular Medicine.

Immune-evasive gene switch enables regulated delivery of chondroitinase after spinal cord injury

A. Didangelos, F. de Winter, J. Verhaagen, 2018, Brain : a journal of neurology.

The use of neurotrophic factors to treat spinal cord injury: advantages and disadvantages of different delivery methods

P. Dijkhuizen, J. Verhaagen, 1999 .

Immunohistochemical, Ultrastructural and Functional Analysis of Axonal Regeneration through Peripheral Nerve Grafts Containing Schwann Cells Expressing BDNF, CNTF or NT3

A. Harvey, M. J. Godinho, G. Plant, 2013, PloS one.

Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior

D. Steindler, F. Verbeek, I. Zalachoras, 2013, Molecular Psychiatry.

The neurotrophic peptide Org 2766 does not influence the expression of the immediate early gene c-fos following sciatic nerve crush in the rat

W. Gispen, J. Verhaagen, P. M. Edwards, 1994, International Journal of Developmental Neuroscience.

Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model

E. Hol, D. Swaab, W. Kamphuis, 2013, Neurobiology of Aging.

Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing

J. Fawcett, L. Saksida, H. Kitagawa, 2021, Molecular Psychiatry.

Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters

James R. Tribble, J. Fawcett, J. Verhaagen, 2023, Gene Therapy.

The Dorsal Column Lesion Model of Spinal Cord Injury and Its Use in Deciphering the Neuron‐Intrinsic Injury Response

J. Verhaagen, C. L. Attwell, M. Mason, 2018, Developmental neurobiology.

Longitudinal in vivo magnetic resonance imaging studies in experimental allergic encephalomyelitis: effect of a neurotrophic treatment on cortical lesion development

K. Nicolay, W. Gispen, J. Verhaagen, 1997, Neuroscience.

Intravitreal Injection of Adeno-associated Viral Vectors Results in the Transduction of Different Types of Retinal Neurons in Neonatal and Adult Rats: A Comparison with Lentiviral Vectors

A. R. Harvey, W. Kamphuis, J. Verhaagen, 2002, Molecular and Cellular Neuroscience.

Small Scale Production of Recombinant Adeno-Associated Viral Vectors for Gene Delivery to the Nervous System.

A. Harvey, E. Ehlert, J. Verhaagen, 2018, Methods in molecular biology.

Expression of class-3 semaphorins and their receptors in the neonatal and adult rat retina.

A. Harvey, F. de Winter, J. Verhaagen, 2004, Investigative ophthalmology & visual science.

Noninvasive Bioluminescence Imaging of Olfactory Ensheathing Glia and Schwann Cells following Transplantation into the Lesioned Rat Spinal Cord

J. Verhaagen, R. Eggers, K. Roet, 2012, Cell transplantation.

Regulation of Semaphorin III/Collapsin-1 Gene Expression during Peripheral Nerve Regeneration

J. Verhaagen, R. Giger, R. Pasterkamp, 1998, Experimental Neurology.

Anatomical distribution of the chemorepellent semaphorin III/collapsin‐1 in the adult rat and human brain: Predominant expression in structures of the olfactory‐hippocampal pathway and the motor system

A. Holtmaat, J. Verhaagen, R. Giger, 1998, Journal of neuroscience research.

The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain

J. Fawcett, G. Neufeld, E. Ehlert, 2013, Molecular and Cellular Neuroscience.

Alpha 9 integrin expression enables reconstruction of the spinal cord sensory pathway

V. Herynek, F. de Winter, J. Verhaagen, 2023, bioRxiv.

Ectopic adenoviral vector-directed expression of Sema3A in organotypic spinal cord explants inhibits growth of primary sensory afferents.

J. Verhaagen, W. Hermens, R. Giger, 2000, Developmental biology.

Neurotrophin receptors in Alzheimer's disease.

D. Swaab, J. Verhaagen, A. Salehi, 1998, Progress in brain research.

Repulsive Guidance Molecule a (RGMa) Induces Neuropathological and Behavioral Changes That Closely Resemble Parkinson's Disease

A. Smit, D. Swaab, R. van Kesteren, 2017, The Journal of Neuroscience.

Elevated expression of B‐50 (GAP‐43)‐mRNA in a subpopulation of olfactory bulb mitral cells following axotomy

W. Gispen, J. Verhaagen, F. Hamers, 1993, Sheng li xue bao : [Acta physiologica Sinica].

Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis

C. V. van Eden, J. Verhaagen, K. Schuurman, 2019, Acta neuropathologica communications.

Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent

J. Fawcett, P. Aebischer, J. Verhaagen, 2016, eNeuro.

Molecular target discovery for neural repair in the functional genomics era.

A. Smit, R. van Kesteren, H. MacGillavry, 2012, Handbook of clinical neurology.

Role for semaphorin III and its receptor neuropilin-1 in neuronal regeneration and scar formation?

F. de Winter, J. Verhaagen, R. Giger, 1998, Progress in brain research.

Wnt Signaling through the Ror Receptor in the Nervous System

M. Malessy, L. Fradkin, J. Verhaagen, 2014, Molecular Neurobiology.

Misdirection and guidance of regenerating axons after experimental nerve injury and repair.

M. Malessy, G. D. de Ruiter, J. Verhaagen, 2014, Journal of neurosurgery.

Differential myofiber-type transduction preference of adeno-associated virus serotypes 6 and 9

J. Verhaagen, S. M. van der Maarel, Y. Raz, 2015, Skeletal Muscle.

The application of gene transfer technology in neurobiology

J. Verhaagen, L. Schrama, Joost Verhaagen, 1997, Journal of Neuroscience Methods.

The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways

J. Fawcett, A. Holtmaat, S. Niclou, 2003, Molecular and Cellular Neuroscience.

AAV vector-mediated secretion of chondroitinase provides a sensitive tracer for axonal arborisations

J. Fawcett, R. Keynes, J. Verhaagen, 2014, Journal of Neuroscience Methods.

Use of viral vectors to promote neuroregeneration.

A. Holtmaat, P. Dijkhuizen, W. Gispen, 1995, Clinical Neuroscience.

Adeno-associated viral vectors as agents for gene delivery: application in disorders and trauma of the central nervous system.

M. Ruitenberg, J. Verhaagen, R. Eggers, 2002, Methods.

Intercostal Nerve Implants Transduced with an Adenoviral Vector Encoding Neurotrophin-3 Promote Regrowth of Injured Rat Corticospinal Tract Fibers and Improve Hindlimb Function

P. Dijkhuizen, J. Verhaagen, G. Boer, 2000, Experimental Neurology.

Adenoviral Vector-Mediated Expression of Neurotrophin-3 Increases Neuronal Survival in Suprachiasmatic Nucleus Grafts

P. Dijkhuizen, J. Verhaagen, W. Hermens, 2001, Experimental Neurology.

Effect of adenoviral vector-mediated expression of neurotrophic3 in suprachiasmatic nucleus transplants on restoration of circadian rhythmicity; preliminary results

P. Dijkhuizen, J. Verhaagen, G. Boer, 2012 .

Transplantation of the rat suprachiasmatic nucleus. Functional studies and ex vivo adenoviral vector-mediated gene transfer

J. Verhaagen, W. Hermens, G. Boer, 1999 .

Adeno-associated viral vector-mediated neurotrophin gene transfer in the injured adult rat spinal cord improves hind-limb function

M. Oudega, J. Verhaagen, G. Boer, 2003, Neuroscience.

Handbook of clinical neurology

L S Illis, L. Illis, J. Verhaagen, 2013, Spinal Cord.

LLM3D: a log-linear modeling-based method to predict functional gene regulatory interactions from genome-wide expression data

Geert Geeven, August B. Smit, A. Smit, 2011, Nucleic acids research.

Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis

C. V. van Eden, J. Verhaagen, K. Schuurman, 2019, Acta Neuropathologica Communications.

Abundant Ecto-ATPase ENTPD2 expression in olfactory ensheathing cells following transplantation in the spinal cord: an explanation for the tissue-protective effects of OEC- transplants?

J. Verhaagen, K. Roet, R. Saavedra-Pascual, 2012 .

Tropism of AAV‐2 vectors for neurons of the globus pallidus

M. Levivier, L. Tenenbaum, T. Velu, 2000, Neuroreport.

Intensity-based analysis of dual-color gene expression data as an alternative to ratio-based analysis to enhance reproducibility

M. A. van de Wiel, B. Ylstra, R. Brakenhoff, 2010, BMC Genomics.

Induction of Brain Region-Specific Forms of Obesity by Agouti

G. Barsh, M. Kas, G. van Dijk, 2004, The Journal of Neuroscience.

Noninvasive Bioluminescence Imaging of Olfactory Ensheathing Glia and Schwann Cells following Transplantation into the Lesioned Rat Spinal Cord

J. Verhaagen, R. Eggers, K. Roet, 2012, Cell transplantation.

Semaphorins and their receptors in olfactory axon guidance.

M. Ruitenberg, J. Verhaagen, R. Pasterkamp, 1999, Cellular and molecular biology.