I. Baró

R. Redon, P. Schwartz, M. Nyegaard, 2020, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains.

S. Severi, G. Loussouarn, I. Baró, 2015, Cardiovascular research.

AKAP proteins anchor cAMP-dependent protein kinase to KvLQT1/IsK channel complex.

J. Scott, D. Escande, I. Baró, 2001, American journal of physiology. Heart and circulatory physiology.

The effects of thapsigargin on [Ca2+]i in isolated rat mesenteric artery vascular smooth muscle cells

I. Baró, D. Eisner, 2004, Pflügers Archiv.

A Dominant Negative Isoform of the Long QT Syndrome 1 Gene Product*

A. Wilde, D. Escande, S. Demolombe, 1998, The Journal of Biological Chemistry.

Transgenic mice overexpressing human KvLQT1 dominant-negative isoform. Part I: Phenotypic characterisation.

A. Moorman, A. Wilde, T. Opthof, 2001, Cardiovascular research.

Atrial fibrillation: is NO an answer for refractoriness?

I. Baró, 2006, Cardiovascular research.

KvLQT1 potassium channel but not IsK is the molecular target for trans-6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethyl- chromane.

D. Escande, F. Charpentier, K. Kunzelmann, 1997, Molecular pharmacology.

Mutation in KCNQ1 that has both recessive and dominant characteristics

W. Reardon, I. Baró, C. Bellocq, 2002, Journal of medical genetics.

TO JMG Mutation in KCNQ 1 that has both recessive and dominant characteristics

W. Reardon, I. Baró, C. Bellocq, 2002 .

SCN5A-related cardiac channelopathy

C. Dina, A. Wilde, F. Charpentier, 2012 .

RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome.

R. Redon, E. Génin, C. Dina, 2018, European heart journal.

Inactivating properties of recombinant ROMK2 channels expressed in mammalian cells.

D. Escande, S. Hebert, G. MacGregor, 2001, Biochemical and biophysical research communications.

(cid:1) 2 -Receptor Ligand-Mediated Inhibition of Inwardly Rectifying K (cid:1) Channels in the Heart

L. Monassier, I. Baró, C. Bellocq, 2007 .

Multifocal Ectopic Purkinje Premature Contractions : a new SCN 5 A-related cardiac channelopathy

C. Dina, A. Wilde, F. Charpentier, 2012 .

Novel SCN5A Mutation Leading Either to Isolated Cardiac Conduction Defect or Brugada Syndrome in a Large French Family

D. Escande, S. Demolombe, J. Chevallier, 2001, Circulation.

Interferon-gamma downregulates CFTR gene expression in epithelial cells.

D. Escande, I. Baró, A. Edelman, 1994, The American journal of physiology.

Barium- and calcium-permeable channels open at negative membrane potentials in rat ventricular myocytes

I. Baró, A. Coulombe, E. Coraboeuf, 1989, The Journal of Membrane Biology.

Modelling sudden cardiac death risks factors in patients with coronavirus disease of 2019: the hydroxychloroquine and azithromycin case

F. Charpentier, G. Loussouarn, I. Baró, 2021, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Changes of intracellular [Ca2+] during refilling of sarcoplasmic reticulum in rat ventricular and vascular smooth muscle.

I. Baró, D. Eisner, S. O'Neill, 1993, The Journal of physiology.

Hyperexpression of recombinant CFTR in heterologous cells alters its physiological properties.

D. Escande, S. Demolombe, H. Pollard, 1998, American journal of physiology. Cell physiology.

Hyperexpression of recombinant CFTR in heterologous cells alters its physiological properties

D. Escande, S. Demolombe, H. Pollard, 1998 .

Expression of CFTR controls cAMP-dependent activation of epithelial K+ currents.

D. Escande, S. Demolombe, G. Loussouarn, 1996, The American journal of physiology.

Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome

F. Charpentier, G. Loussouarn, I. Baró, 2015, Journal of the American Heart Association.

HIV-Tat induces a decrease in IKr and IKsvia reduction in phosphatidylinositol-(4,5)-bisphosphate availability.

Bruno Beaumelle, Isabelle Baró, Gildas Loussouarn, 2016, Journal of molecular and cellular cardiology.

Dysfunction of the Voltage‐Gated K+ Channel β2 Subunit in a Familial Case of Brugada Syndrome

R. Redon, C. Dina, Céline Marionneau, 2016, Journal of the American Heart Association.

A consistent arrhythmogenic trait in Brugada syndrome cellular phenotype

R. Redon, F. Charpentier, V. Probst, 2021, Clinical and translational medicine.

Haploinsufficiency in combination with aging causes SCN5A-linked hereditary Lenègre disease.

D. Escande, S. Demolombe, J. Trochu, 2003, Journal of the American College of Cardiology.

OP-EHEA190316_online 3081..3094

R. Redon, C. Dina, Céline Marionneau, 2021 .

Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 Comparison

Céline Marionneau, F. Charpentier, Y. Péréon, 2016, Front. Pharmacol..

Mouse Models of SCN5A-Related Cardiac Arrhythmias

F. Charpentier, I. Baró, J. Montnach, 2012, Front. Physio..

Physiological and Pathophysiological Insights of Nav1.4 and Nav1.5 Comparison

Céline Marionneau, F. Charpentier, Y. Péréon, 2016, Front. Pharmacol..

Opposite Effects of the S4–S5 Linker and PIP2 on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels

G. Loussouarn, I. Baró, F. Abderemane-Ali, 2012, Front. Pharmacol..

Delayed rectifier K(+) currents and cardiac repolarization.

F. Charpentier, G. Loussouarn, I. Baró, 2010, Journal of molecular and cellular cardiology.

Mutations in a dominant-negative isoform correlate with phenotype in inherited cardiac arrhythmias.

D. Escande, S. Demolombe, F. Kyndt, 1999, American journal of human genetics.

A Common Antitussive Drug, Clobutinol, Precipitates the Long QT Syndrome 2

Ronald Wilders, Isabelle Baró, Denis Escande, 2004, Molecular Pharmacology.

Intracellular pH and buffering power measured in isolated single cells from pregnant rat uterus

S. Wray, I. Baró, S. Raimbach, 1991, Experimental physiology.

A long lasting Ca2+ -activated outward current in guinea-pig atrial myocytes

D. Escande, I. Baró, 1989, Pflügers Archiv.

Phosphatidylinositol‐4,5‐bisphosphate, PIP2, controls KCNQ1/KCNE1 voltage‐gated potassium channels: a functional homology between voltage‐gated and inward rectifier K+ channels

D. Escande, F. Charpentier, G. Loussouarn, 2003, The EMBO journal.

ATP-sensitive K+ channels regulated by intracellular Ca2+ and phosphorylation in normal (T84) and cystic fibrosis (CFPAC-1) epithelial cells

D. Escande, I. Baró, A. -. Hongre, 2004, Pflügers Archiv.

Neural modulation of ion channels in cardiac arrhythmias: clinical implications and future investigations.

G. Loussouarn, I. Baró, 2010, Heart rhythm.

Impaired KCNQ1–KCNE1 and Phosphatidylinositol-4,5-Bisphosphate Interaction Underlies the Long QT Syndrome

Kyu-Ho Park, Shehrazade Dahimene, Isabelle Baró, 2005, Circulation research.

Multifocal Ectopic Purkinje-Related Premature Contractions A New SCN5A -Related Cardiac Channelopathy

C. Dina, A. Wilde, F. Charpentier, 2012 .

Dynamic analysis of the QT interval in long QT1 syndrome patients with a normal phenotype.

D. Escande, F. Kyndt, I. Baró, 2001, European heart journal.

Arrhythmias precede cardiomyopathy and remodeling of Ca2+ handling proteins in a novel model of long QT syndrome.

F. Charpentier, G. Loussouarn, I. Baró, 2018, Journal of molecular and cellular cardiology.

Complex Brugada syndrome inheritance in a family harbouring compound SCN5A and CACNA1C mutations

R. Redon, D. Pavin, V. Probst, 2014, Basic Research in Cardiology.

Transforming growth factor &bgr; receptor inhibition prevents ventricular fibrosis in a mouse model of progressive cardiac conduction disease

F. Charpentier, W. Colledge, A. Grace, 2017, Cardiovascular research.

Torsades de pointes complicating atrioventricular block: evidence for a genetic predisposition.

H. Lemarec, J. Barhanin, J. Schott, 2007, Heart rhythm.

Basic Physiology of Ion Channel Function

Isabelle Baró, Denis Escande, D. Escande, 2008 .

Computer modeling of whole-cell voltage-clamp analyses to delineate guidelines for good practice of manual and automated patch-clamp

Isabelle Baró, Gildas Loussouarn, Jérôme Montnach, 2020, Scientific Reports.

KCNQ1 Channels Voltage Dependence through a Voltage-dependent Binding of the S4-S5 Linker to the Pore Domain*

D. Escande, F. Charpentier, G. Loussouarn, 2010, The Journal of Biological Chemistry.

Kv7.1 (KCNQ1) properties and channelopathies

G. Loussouarn, I. Baró, F. Choveau, 2008, The Journal of physiology.

β3-Adrenoceptor Control the Cystic Fibrosis Transmembrane Conductance Regulator through a cAMP/Protein Kinase A-independent Pathway*

D. Escande, S. Demolombe, D. Langin, 1999, The Journal of Biological Chemistry.

The N-Terminal Juxtamembranous Domain of KCNQ1 Is Critical for Channel Surface Expression: Implications in the Romano-Ward LQT1 Syndrome

Isabelle Baró, Denis Escande, Annick Thomas, 2006, Circulation research.

Concomitant activation of Cl‐ and K+ currents by secretory stimulation in human epithelial cells.

D. Escande, I. Baró, A. -. Hongre, 1994, The Journal of physiology.

SARS-CoV-2 E and 3a Proteins Are Inducers of Pannexin Currents

F. Charpentier, N. Escriou, G. Loussouarn, 2022, bioRxiv.

Differential expression of KvLQT1 isoforms across the human ventricular wall.

D. Escande, S. Demolombe, F. Charpentier, 2000, American journal of physiology. Heart and circulatory physiology.

Microarray Analysis Reveals Complex Remodeling of Cardiac Ion Channel Expression With Altered Thyroid Status: Relation to Cellular and Integrated Electrophysiology

J. Nerbonne, J. Léger, D. Escande, 2003, Circulation research.

A Long QT Mutation Substitutes Cholesterol for Phosphatidylinositol-4,5-Bisphosphate in KCNQ1 Channel Regulation

Annick Thomas, R. Brasseur, Céline Marionneau, 2014, PloS one.

LQT1-associated Mutations Increase KCNQ1 Proteasomal Degradation Independently of Derlin-1*

G. Loussouarn, I. Baró, David Péroz, 2009, Journal of Biological Chemistry.

Predicting hERG repolarization power at 37°C from recordings at room temperature

F. Charpentier, G. Loussouarn, I. Baró, 2023, bioRxiv.

A standardised hERG phenotyping pipeline to evaluate KCNH2 genetic variant pathogenicity

V. Probst, J. Barc, F. Kyndt, 2021, Clinical and translational medicine.

Gap-134, a Connexin43 activator, prevents age-related development of ventricular fibrosis in Scn5a+/- mice.

F. Charpentier, Audrey Donnart, A. Bihouée, 2020, Pharmacological research.

S. Hohnloser, S. Nattel, R. Brandes, 2009, Heart Rhythm.

Multifocal ectopic Purkinje-related premature contractions: a new SCN5A-related cardiac channelopathy.

F. Charpentier, Y. Coudière, L. Faivre, 2012, Journal of the American College of Cardiology.

Multifocal Ectopic Purkinje-related Premature Contractions a New Scn5a-related Cardiac Channelopathy

F. Charpentier, Y. Coudière, C. Thauvin-Robinet, 2022 .

RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome.

R. Redon, E. Génin, C. Dina, 2019, European heart journal.

Non-invasive testing of acquired long QT syndrome: evidence for multiple arrhythmogenic substrates.

P. Touboul, G. Kirkorian, J. Schott, 2001, Cardiovascular research.

Precipitates the Long QT2 Syndrome

D. Escande, R. Wilders, J. Schott, 2004 .

Modeling sudden cardiac death risks factors in COVID-19 patients -the hydroxychloroquine and azithromycin case

F. Charpentier, G. Loussouarn, I. Baró, 2023 .

IKs response to protein kinase A-dependent KCNQ1 phosphorylation requires direct interaction with microtubules.

R. Kass, D. Escande, J. Camonis, 2008, Cardiovascular Research.

KCNE1–KCNQ1 osmoregulation by interaction of phosphatidylinositol‐4,5‐bisphosphate with Mg2+ and polyamines

F. Charpentier, G. Loussouarn, I. Baró, 2010, The Journal of physiology.