G. Costin

发表

Human skin pigmentation: melanocytes modulate skin color in response to stress

V. Hearing, G. Costin, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Targeted drug delivery

R. Dwek, S. Petrescu, N. Nichita, 1986 .

Mutations in dopachrome tautomerase (Dct) affect eumelanin/pheomelanin synthesis, but do not affect intracellular trafficking of the mutant protein.

A. Milac, K. Wakamatsu, S. Ito, 2005, The Biochemical journal.

IN VITRO SAFETY TESTING STRATEGY FOR SKIN IRRITATION USING THE 3D RECONSTRUCTED HUMAN EPIDERMIS

G. Costin, R. Curren, H. Raabe, 2009 .

Evaluation of a tiered in vitro testing strategy for assessing the ocular and dermal irritation/corrosion potential of pharmaceutical compounds for worker safety

Elizabeth A. Sly, G. Costin, J. Gould, 2018, Cutaneous and ocular toxicology.

Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the underwhite (uw) mutation. A model for oculocutaneous albinism (OCA) type 4

V. Hearing, G. Costin, J. Valencia, 2003, Journal of Cell Science.

Vaginal Irritation Models: The Current Status of Available Alternative and In Vitro Tests

G. Costin, R. Curren, H. Raabe, 2011, Alternatives to laboratory animals : ATLA.

Sialylated Core 1 O-Glycans Influence the Sorting of Pmel17/gp100 and Determine Its Capacity to Form Fibrils*

K. Nagashima, E. Appella, H. Yamaguchi, 2007, Journal of Biological Chemistry.

Cellular and molecular mechanisms involved in the action of vitamin D analogs targeting vitiligo depigmentation.

G. Costin, S. Birlea, D. Norris, 2008, Current drug targets.

Biphasic pro-melanogenic and pro-apoptotic effects of all-trans-retinoic acid (ATRA) on human melanocytes: time-course study.

K. Kechris, G. Costin, A. Filip, 2013, Journal of dermatological science.

pH-sensitive liposomes are efficient carriers for endoplasmic reticulum-targeted drugs in mouse melanoma cells.

R. Dwek, S. Petrescu, N. Nichita, 2002, Biochemical and biophysical research communications.

The etiology of oculocutaneous albinism (OCA) type II: the pink protein modulates the processing and transport of tyrosinase.

V. Ferrans, V. Hearing, V. Virador, 2002, Pigment cell research.

New insights on therapy with vitamin D analogs targeting the intracellular pathways that control repigmentation in human vitiligo

G. Costin, S. Birlea, D. Norris, 2009, Medicinal research reviews.

Trends in Regenerative Medicine: Repigmentation in Vitiligo Through Melanocyte Stem Cell Mobilization

D. Roop, G. Costin, S. Birlea, 2017, Medicinal research reviews.

Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease

David W. Miller, A. Singleton, E. Bergantino, 2005, Journal of neurochemistry.

What is the mechanism for melasma that so commonly accompanies human pregnancy?

G. Costin, S. Birlea, 2006, IUBMB life.

Intracellular composition of fatty acid affects the processing and function of tyrosinase through the ubiquitin-proteasome pathway.

M. Ichihashi, V. Hearing, Hee-Yong Kim, 2006, The Biochemical journal.

Regulation of constitutive and UVR‐induced skin pigmentation by melanocortin 1 receptor isoforms

Z. Abdel‐Malek, V. Hearing, G. Costin, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Regulation of melanocortin 1 receptor expression at the mRNA and protein levels by its natural agonist and antagonist

J. Annereau, V. Hearing, G. Costin, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Optimizied in vitro pigmentation screening assay using a reconstructed three dimensional human skin model.

G. Costin, H. Raabe, 2013 .

The Seiji memorial lecture: the melanosome: an ideal model to study cellular differentiation.

V. Hearing, G. Costin, K. Yasumoto, 2003, Pigment cell research.

Confirmation of in vitro and clinical safety assessment of behentrimonium chloride-containing leave-on body lotions using post-marketing adverse event data.

G. Costin, J. Avalos, W. Billhimer, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

Immortalization of mouse melanocytes carrying mutations in various pigmentation genes.

V. Hearing, G. Costin, F. Rouzaud, 2004, Analytical biochemistry.

In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Response

Michael J. Fevola, R. Walters, G. Costin, 2016, Alternatives to laboratory animals : ATLA.

In Vitro Toxicology Models

Gertrude-Emilia Costin, Hans Raabe, G. Costin, 2014 .

Application of In Vitro Methods in Preclinical Safety Assessment of Skin Care Products

G. Costin, K. Norman, 2017 .

Emerging trends in science and education: introducing the 3Rs concepts into pre-college classrooms

G. Costin, Adele Miller, 2020, Journal of Biological Education.

Qualification of a non-animal vaginal irritation method admitted as nonclinical assessment model (NAM) in the Incubator Phase of the United States Food and Drug Administration (US FDA) Medical Devices Development Tool (MDDT).

G. Costin, E. Hill, A. Clippinger, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Trends in wound repair: cellular and molecular basis of regenerative therapy using electromagnetic fields.

G. Costin, S. Birlea, David A. Norris, 2012, Current molecular medicine.