P. Crépieux

发表

Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling

François Fages, Frédérique Clément, Anne Poupon, 2012, Molecular systems biology.

MAbTope: A Method for Improved Epitope Mapping

A. Poupon, N. Gallay, P. Crépieux, 2018, The Journal of Immunology.

Towards a systems biology approach of-G protein-coupled receptor signalling: challenges and expectations.

F. Fages, A. Poupon, D. Heitzler, 2009, Comptes rendus biologies.

GPCR signalling to the translation machinery.

P. Crépieux, E. Reiter, A. Musnier, 2010, Cellular signalling.

Unraveling the molecular architecture of a G protein-coupled receptor/β-arrestin/Erk module complex

D. Ritchie, A. Poupon, J. Azé, 2015, Scientific Reports.

Profiling of FSHR negative allosteric modulators on LH/CGR reveals biased antagonism with implications in steroidogenesis

A. Poupon, R. Yvinec, G. Jégot, 2016, Molecular and Cellular Endocrinology.

Phosphorylation of β-arrestin2 at Thr383 by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs

P. Marin, J. Bockaert, A. Poupon, 2017, eLife.

A Comprehensive View of the β-Arrestinome

Martin H. Schaefer, Luis Serrano, Anne Poupon, 2017, Front. Endocrinol..

Activation of a GPCR leads to eIF4G phosphorylation at the 5' cap and to IRES-dependent translation.

R. Backofen, J. Morales, A. Poupon, 2014, Journal of molecular endocrinology.

Follicle-Stimulating Hormone Receptor: Advances and Remaining Challenges.

A. Poupon, R. Yvinec, P. Crépieux, 2018, International review of cell and molecular biology.

Advances in computational modeling approaches of pituitary gonadotropin signaling

A. Poupon, R. Yvinec, P. Crépieux, 2018, Expert opinion on drug discovery.

Direct impact of gonadotropins on glucose uptake and storage.

T. G. Shrivastav, Surleen Kaur, P. Crépieux, 2020, Metabolism: clinical and experimental.

Mathematical modeling approaches of cellular endocrinology within the hypothalamo-pituitary-gonadal axis

R. Yvinec, D. Monniaux, P. Crépieux, 2020, Molecular and Cellular Endocrinology.

Preferential β-arrestin signalling at low receptor density revealed by functional characterization of the human FSH receptor A189 V mutation

G. Durand, C. Gauthier, P. Crépieux, 2011, Molecular and Cellular Endocrinology.

Reduced FSH and LH action: implications for medically assisted reproduction

N. Raine-Fenning, M. Simoni, A. Hanyaloglu, 2021, Human reproduction.

The Ets family of proteins: weak modulators of gene expression in quest for transcriptional partners.

P. Crépieux, J. Coll, D. Stéhelin, 1994, Critical reviews in oncogenesis.

A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation.

C. Gauthier, V. Piketty, P. Crépieux, 2006, Molecular endocrinology.

Dichlorodiphenyltrichloroethane impairs follicle-stimulating hormone receptor-mediated signaling in rat Sertoli cells.

Pascale Crépieux, Eric Reiter, Anne Tilloy-Ellul, 2007, Reproductive toxicology.

The RNA-binding protein Mex3b regulates the spatial organization of the Rap1 pathway

D. Nègre, Julien Courchet, D. Segretain, 2014, Development.

A highly sensitive near‐infrared fluorescent detection method to analyze signalling pathways by reverse‐phase protein array

D. Heitzler, G. Durand, L. Dupuy, 2009, Proteomics.

Molecular Mechanisms of Action of FSH

P. Crépieux, L. Casarini, 2019, Front. Endocrinol..

Sertoli and granulosa cell‐specific Cre recombinase activity in transgenic mice

C. Lécureuil, P. Crépieux, I. Fontaine, 2002, Genesis.

Dimeric Transferrin Inhibits Phagocytosis of Residual Bodies by Testicular Rat Sertoli Cells1

O. Benzakour, M. Maurel, P. Crépieux, 2008, Biology of reproduction.

G Protein-Coupled Receptor Kinases and Beta Arrestins Are Relocalized and Attenuate Cyclic 3′,5′-Adenosine Monophosphate Response to Follicle-Stimulating Hormone in Rat Primary Sertoli Cells1

P. Crépieux, E. Reiter, S. Marion, 2002, Biology of reproduction.

Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

Lee B. Smith, B. Vanhaesebroeck, W. Pearce, 2015, PLoS genetics.

Partially deglycosylated equine LH preferentially activates beta-arrestin-dependent signaling at the follicle-stimulating hormone receptor.

Vladimir Y. Butnev, G. Bousfield, M. Maurel, 2010, Molecular endocrinology.

Taxol selectively blocks microtubule dependent NF-κB activation by phorbol ester via inhibition of IκBα phosphorylation and degradation

N. Leclerc, H. Kwon, J. Hiscott, 1999, Oncogene.

Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor

A. Poupon, R. Yvinec, S. Palmer, 2021, International journal of molecular sciences.

I k B a Physically Interacts with a Cytoskeleton-Associated Protein through Its Signal Response Domain

N. Leclerc, S. Richard, H. Kwon, 1997 .

Taxol selectively blocks microtubule dependent NF-kappaB activation by phorbol ester via inhibition of IkappaBalpha phosphorylation and degradation.

N. Leclerc, H. Kwon, J. Hiscott, 1999, Oncogene.

Follicle-stimulating hormone activates p70 ribosomal protein S6 kinase by protein kinase A-mediated dephosphorylation of Thr 421/Ser 424 in primary Sertoli cells.

S. Tesseraud, C. Lécureuil, C. Gauthier, 2005, Molecular endocrinology.

Cellular and viral protein interactions regulating IκBα activity during human retrovirus infection

H. Kwon, J. Hiscott, P. Beauparlant, 1997, Journal of leukocyte biology.

Phylogeny of the p68c-ets-1 amino-terminal transactivating domain reveals some highly conserved structural features.

D. Leprince, P. Crépieux, D. Stéhelin, 1992, Oncogene.

c-ets-1 DNA binding to the PEA3 motif is differentially inhibited by all the mutations found in v-ets.

D. Leprince, P. Crépieux, D. Stéhelin, 1992, Oncogene.

Extracellular signal-regulated kinases (ERK) 1, 2 are required for luteinizing hormone (LH)-induced steroidogenesis in primary Leydig cells and control steroidogenic acute regulatory (StAR) expression.

P. Crépieux, E. Reiter, F. Guillou, 2005, Reproduction, nutrition, development.

during human retrovirus infection

H. Kwon, J. Hiscott, P. Beauparlant, 1997 .

Methionine deprivation regulates the S6K1 pathway and protein synthesis in avian QM7 myoblasts without activating the GCN2/eIF2 alpha cascade.

I. Seiliez, S. Tesseraud, S. Crochet, 2010, The Journal of nutrition.

Follicle-stimulating hormone (FSH) activates extracellular signal-regulated kinase phosphorylation independently of beta-arrestin- and dynamin-mediated FSH receptor internalization

V. Piketty, P. Crépieux, E. Reiter, 2006, Reproductive biology and endocrinology : RB&E.

Kinase-inactive G-protein-coupled receptor kinases are able to attenuate follicle-stimulating hormone-induced signaling.

P. Crépieux, E. Reiter, S. Marion, 2001, Biochemical and biophysical research communications.

FSH-stimulated PTEN activity accounts for the lack of FSH mitogenic effect in prepubertal rat Sertoli cells

H. Guillou, J. Dupont, S. Nef, 2010, Molecular and Cellular Endocrinology.

Receptors | Thyroid-Stimulating Hormone/Luteinizing Hormone/Follicle-Stimulating Hormone Receptors

Y. Combarnous, P. Crépieux, E. Reiter, 2020 .

Intracellular VHHs to monitor and modulate GPCR signaling

P. Crépieux, E. Reiter, V. Jugnarain, 2022, Frontiers in Endocrinology.

Series: “Encyclopedia of the Molecular Life Sciences” Volume: “Biological Signaling” Section: “Coupling of Recognition and Effect” Title: “Coupling of recognition and effect in GPCR signaling: computational modelling

R. Yvinec, P. Crépieux, E. Reiter, 2016 .

Hydrocortisone modulates the expression of c-ets-1 and 72 kDa type IV collagenase in chicken dermis during early feather morphogenesis.

P. Crépieux, D. Stéhelin, G. Buttice, 1997, The International journal of developmental biology.

Rel/NF-kappa B transcription factors and I kappa B inhibitors: evolution from a unique common ancestor.

V. Laudet, P. Crépieux, C. Huguet, 1997, Oncogene.

Human Monocytic Cell Lines Transformed In Vitro by Epstein-Barr Virus Display a Type II Latency and LMP-1-Dependent Proliferation

C. Montpellier, P. Crépieux, E. Adriaenssens, 2002, Journal of Virology.

Methods to Determine Interaction Interfaces Between β-Arrestins and Their Protein Partners.

A. Poupon, P. Crépieux, E. Reiter, 2019, Methods in molecular biology.

G Protein-Coupled Receptors As Regulators of Localized Translation: The Forgotten Pathway?

P. Crépieux, E. Reiter, F. Guillou, 2018, Front. Endocrinol..

G protein‐dependent signaling triggers a β‐arrestin‐scaffolded p70S6K/ rpS6 module that controls 5'TOP mRNA translation

A. Poupon, S. Tesseraud, A. Inoue, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mapping the Follicle-Stimulating Hormone-Induced Signaling Networks

Anne Poupon, Domitille Heitzler, Pascale Crépieux, 2011, Front. Endocrin..

G protein-coupled receptor kinase 2 and beta-arrestins are recruited to FSH receptor in stimulated rat primary Sertoli cells.

V. Piketty, P. Crépieux, E. Reiter, 2006, The Journal of endocrinology.

A mechanistic overview on male infertility and germ cell cancers.

C. Lécureuil, V. Piketty, P. Crépieux, 2004, Current pharmaceutical design.

Rel/NF-κB transcription factors and IκB inhibitors: Evolution from a unique common ancestor

V. Laudet, P. Crépieux, C. Huguet, 1997, Oncogene.

mRNA-selective translation induced by FSH in primary Sertoli cells.

J. Morales, A. Poupon, P. Vourc'h, 2012, Molecular endocrinology.

Novel pathways in gonadotropin receptor signaling and biased agonism

A. Poupon, M. Maurel, P. Crépieux, 2011, Reviews in Endocrine and Metabolic Disorders.

Biased Signaling and Allosteric Modulation at the FSHR

A. Poupon, R. Yvinec, P. Crépieux, 2019, Front. Endocrinol..

Follicle-Stimulating Hormone (FSH) Action on Spermatogenesis: A Focus on Physiological and Therapeutic Roles

D. Santi, G. Spaggiari, M. Simoni, 2020, Journal of clinical medicine.

FSH for the Treatment of Male Infertility

D. Santi, M. Simoni, P. Crépieux, 2020, International journal of molecular sciences.

The ERK-dependent signalling is stage-specifically modulated by FSH, during primary Sertoli cell maturation

Pascale Crépieux, Eric Reiter, Florian Guillou, 2001, Oncogene.

Developmental regulation of p70 S6 kinase by a G protein-coupled receptor dynamically modelized in primary cells

H. Guillou, A. Poupon, S. Tesseraud, 2009, Cellular and Molecular Life Sciences.

FSH Receptor Signaling: Complexity of Interactions and Signal Diversity

P. Crépieux, E. Reiter, A. Ulloa-Aguirre, 2018, Endocrinology.

Biased signalling in follicle stimulating hormone action

A. Poupon, G. Jégot, G. Durand, 2014, Molecular and Cellular Endocrinology.

Integrating microRNAs into the complexity of gonadotropin signaling networks

A. Poupon, N. Gallay, P. Crépieux, 2013, Front. Cell Dev. Biol..

The Follicle-Stimulating Hormone Signaling Network in Gonadal Cells

R. Yvinec, N. Gallay, P. Crépieux, 2021 .

Cellular adhesion of primary Sertoli cells affects responsiveness of the extracellular signal-regulated kinases 1 and 2 to follicle-stimulating hormone but not to epidermal growth factor.

P. Crépieux, E. Reiter, S. Marion, 2002, Archives of biochemistry and biophysics.

The Follicle-Stimulating Hormone Signaling Network in Sertoli Cells

N. Gallay, P. Crépieux, F. Guillou, 2014 .

I kappaB alpha physically interacts with a cytoskeleton-associated protein through its signal response domain

N. Leclerc, H. Kwon, J. Hiscott, 1997, Molecular and cellular biology.

The RNA-binding protein Mex 3 b regulates the spatial organization of the Rap 1 pathway

D. Nègre, Julien Courchet, D. Segretain, 2014 .

β-arrestin signalling and bias in hormone-responsive GPCRs

A. Poupon, R. Yvinec, P. Crépieux, 2017, Molecular and Cellular Endocrinology.

Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges

M. Parmentier, J. Steyaert, J. Pin, 2017, mAbs.

TATA-less promoters of some Ets-family genes are efficiently repressed by wild-type p53.

V. Laudet, V. Iotsova, C. Montpellier, 1996, Oncogene.

A New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs and Accurately Predicts Off-Target Reactivity

A. Poupon, N. Gallay, P. Crépieux, 2022, International journal of molecular sciences.

Computational modeling approaches in gonadotropin signaling.

A. Poupon, R. Yvinec, P. Crépieux, 2016, Theriogenology.

A logic-based method to build signaling networks and propose experimental plans

Christine Froidevaux, Anne Poupon, Adrien Rougny, 2018, Scientific Reports.

Serum-induced inhibition of myogenesis is differentially relieved by retinoic acid and triiodothyronine in C2 murine muscle cells.

A. Bonnieu, G. Carnac, P. Crépieux, 1993, Differentiation; research in biological diversity.

Accurate determination of epitope for antibodies with unknown 3D structures

A. Poupon, P. Crépieux, E. Reiter, 2021, mAbs.

Assessing Gonadotropin Receptor Function by Resonance Energy Transfer-Based Assays

A. Poupon, G. Jégot, N. Gallay, 2015, Front. Endocrinol..

Workflow Description to Dynamically Model β-Arrestin Signaling Networks.

Anne Poupon, Pascale Crépieux, Eric Reiter, 2018, Methods in molecular biology.

Identification of a second promoter in the human c-ets-2 proto-oncogene.

V. Laudet, P. Crépieux, D. Stéhelin, 1997, Gene expression.

A logic-based method to build signaling networks and propose experimental plans

A. Poupon, P. Crépieux, E. Reiter, 2018, Scientific Reports.

β-Arrestins and Endocrine-Related GPCRs

A. Poupon, R. Yvinec, P. Crépieux, 2021 .

The two functionally distinct amino termini of chicken c-ets-1 products arise from alternative promoter usage.

D. Leprince, P. Crépieux, D. Stéhelin, 1993, Gene expression.

Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR

A. Poupon, P. Crépieux, V. Jugnarain, 2023, International journal of molecular sciences.

Towards the convergent therapeutic potential of GPCRs in autism spectrum disorders.

P. Crépieux, L. Pellissier, V. Bozon, 2022, British journal of pharmacology.

Reproductive Biology and Endocrinology Follicle-stimulating Hormone (fsh) Activates Extracellular Signal-regulated Kinase Phosphorylation Independently of Beta-arrestin-and Dynamin-mediated Fsh Receptor Internalization

V. Piketty, P. Crépieux, E. Reiter, 2022 .