Mingtao Ao

发表

The molecular mechanism of hPPARα activation

Bowen Tang, Boqun Li, Yuqing Qian, 2017 .

A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter

Qiang Zhou, Mingtao Ao, Meijuan Fang, 2017, Scientific Reports.

New napelline-type diterpenoid alkaloids from Aconiti kusnezoffii roots: Structure elucidation, plausible biogenetic pathway and biological activities

Mingtao Ao, Cuicui Liu, Nannan Chen, 2021 .

Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors.

Boqun Li, Mingtao Ao, Meijuan Fang, 2020, Bioorganic chemistry.

The synthesis of PROTAC molecule and new target KAT6A identification of CDK9 inhibitor iCDK9

Zhanghua Wu, Mingtao Ao, Meijuan Fang, 2022, Chinese Chemical Letters.

Imaging-guided synergistic targeting-promoted photo-chemotherapy against cancers by methotrexate-conjugated hyaluronic acid nanoparticles

Yuemao Shen, Mengya Zhong, Mingtao Ao, 2020 .

Design, synthesis, and biological evaluation of AV6 derivatives as novel dual reactivators of latent HIV-1

Bowen Tang, Yuqing Qian, Mingtao Ao, 2018, RSC advances.

Design and synthesis of N-(1-(6-(substituted phenyl)-pyridazin-3-yl)-piperidine-3-yl)-amine derivatives as JMJD6 inhibitors.

Zhanghua Wu, Boqun Li, Yuqing Qian, 2022, Bioorganic chemistry.

A chalcone derivative reactivates latent HIV-1 transcription through activating P-TEFb and promoting Tat-SEC interaction on viral promoter

Qiang Zhou, Mingtao Ao, Meijuan Fang, 2017, Scientific Reports.

Design, synthesis, and biological evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-Indole-2-Carbohydrazide derivatives: the methuosis inducer 12A as a Novel and selective anticancer agent

Mingtao Ao, Meijuan Fang, Yafei Guo, 2021, Journal of enzyme inhibition and medicinal chemistry.

PEG–lipid–PLGA hybrid nanoparticles loaded with berberine–phospholipid complex to facilitate the oral delivery efficiency

Mingtao Ao, Z. Qi, Yang Li, 2017, Drug delivery.

Design and synthesis of adamantyl-substituted flavonoid derivatives as anti-inflammatory Nur77 modulators: Compound B7 targets Nur77 and improves LPS-induced inflammation in vitro and in vivo.

Zhanghua Wu, Boqun Li, Yuqing Qian, 2022, Bioorganic chemistry.

Synthesis and discovery of ω-3 polyunsaturated fatty acid- alkanolamine (PUFA-AA) derivatives as anti-inflammatory agents targeting Nur77.

Yuqing Qian, Mingtao Ao, Meijuan Fang, 2020, Bioorganic chemistry.

Carrier-free nanoparticles of camptothecin prodrug for chemo-photothermal therapy: the making, in vitro and in vivo testing

Mengya Zhong, Mingtao Ao, Xiaolian Sun, 2021, Journal of Nanobiotechnology.

Synthesis and biological evaluation of 1-(2-(adamantane-1-yl)-1H-indol-5-yl)-3-substituted urea/thiourea derivatives as anticancer agents

Bowen Tang, Mingtao Ao, Xiaoxiao Zhou, 2017 .

Synthesis, structure–activity relationship studies and biological evaluation of novel 2,5‐disubstituted indole derivatives as anticancer agents

Mingtao Ao, Meijuan Fang, Zhen Wu, 2016, Chemical biology & drug design.

Discovery of new chalone adamantyl arotinoids having RXRα-modulating and anticancer activities.

Xian-wen Hu, Fuquan Jiang, Boqun Li, 2021, Bioorganic chemistry.

Inhibition of Nur77 expression and translocation by compound B6 reduces ER stress and alleviates cigarette smoke-induced inflammation and injury in bronchial epithelial cells

Mingtao Ao, Baicun Li, Weiyu Li, 2023, Frontiers in Pharmacology.

Discovery of 4-((3,4-dichlorophenyl)amino)-2-methylquinolin-6-ol derivatives as EGFR and HDAC dual inhibitors

Yuqing Qian, Mingtao Ao, Yin Cao, 2023, European Journal of Pharmacology.

The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma

Mingtao Ao, Kaiqiang Guo, Wen Liu, 2023, British Journal of Cancer.