J. Hoflack

发表

Contribution of unusual Arginine-Arginine short-range interactions to stabilization and recognition in proteins

H. Scheraga, B. Maigret, A. Magalhães, 1994, Journal of protein chemistry.

Modeling of G-protein-coupled receptors: application to dopamine, adrenaline, serotonin, acetylcholine, and mammalian opsin receptors.

J Hoflack, S. Trumpp-Kallmeyer, J. Hoflack, 1992, Journal of medicinal chemistry.

Modeling of G-Protein-Coupled Receptors

Susanne Trumpp-Kallmeyer, Jan Hoflack, Marcel Hibert, 1994 .

Modelling of the binding site of the human m1 muscarinic receptor: Experimental validation and refinement

Susanne Trumpp-Kallmeyer, Hélène Bourdon, Herman Schreuder, 1997, J. Comput. Aided Mol. Des..

Three-dimensional models of G-protein coupled receptors

Jan Hoflack, Marcel Hibert, S. Trumpp-Kallmeyer, 1993 .

Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva‐Derived Endothelial Cells

M. Goumans, A. Bullock, P. Koolwijk, 2019, JBMR plus.

Synthesis of hexadeuterated hexestrol (R, S)-3,4-di-(4-hydroxyphenyl)hexane-1,1,1,6,6,6-2H6

J. Hoflack, C. Peteghem, P. D. Clercq, 1985 .

The sca program : an easy way for the conformational evaluation of polycyclic molecules

Jan Hoflack, J. Hoflack, P. D. Clercq, 1988 .

Modelling and modification of the binding site of endothelin and other receptors.

S. Trumpp-Kallmeyer, J. Hoflack, M. Hibert, 1993, European journal of pharmacology.

The Binding Site of Neuropeptide Vasopressin V1a Receptor

J Hoflack, S. Trumpp-Kallmeyer, B. Mouillac, 1995, The Journal of Biological Chemistry.

Structure of neuropeptide Y dimer in solution.

D. J. Cowley, V. Saudek, J. Hoflack, 1992, European journal of biochemistry.

Three-dimensional models of neurotransmitter G-binding protein-coupled receptors.

J Hoflack, S. Trumpp-Kallmeyer, J. Hoflack, 1991, Molecular pharmacology.

Three-dimensional models of gonado-thyrotropin hormone receptor transmembrane domain.

S. Trumpp-Kallmeyer, J. Bidart, J. Hoflack, 1993, Drug design and discovery.

This is not a G protein-coupled receptor.

S. Trumpp-Kallmeyer, J. Hoflack, M. Hibert, 1993, Trends in pharmacological sciences.

In Vivo Inhibition of RIPK2 Kinase Alleviates Inflammatory Disease*

Xiaodong Bai, Derek W. Abbott, F. Cominelli, 2014, The Journal of Biological Chemistry.

Tyr115 is the key residue for determining agonist selectivity in the V1a vasopressin receptor.

J Hoflack, S. Trumpp-Kallmeyer, M. Manning, 1995, The EMBO journal.

Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors

Jiang Ren, J. Hoflack, P. ten Dijke, 2021, Cancers.

Computational simulations of the conformational behaviour of the adhesive proteins RGDS fragment

Bernard Maigret, M. Cotrait, M. Kreissler, 1992, J. Comput. Aided Mol. Des..

Two aromatic residues regulate the response of the human oxytocin receptor to the partial agonist arginine vasopressin

S. Trumpp-Kallmeyer, B. Mouillac, J. Hoflack, 1996, FEBS letters.

Receptor-Ligand Interactions in Pharmacology and Drug Design

J. Hoflack, M. Hibert, S. Trumpp-Kallmeyer, 1994 .

Towards understanding the role of the first extracellular loop for the binding of peptide hormones to G-protein coupled receptors.

S. Trumpp-Kallmeyer, B. Mouillac, J. Hoflack, 1995, Pharmaceutica acta Helvetiae.

Intramolecular Diels-Alder Reaction with Furan-Diene: Syntheses of Gibberellins (+)-GA1 and (+)-GA3

G. Appendino, J. Hoflack, P. D. Clercq, 1995 .

Re-evaluation of bacteriorhodopsin as a model for G protein-coupled receptors.

J Hoflack, S. Trumpp-Kallmeyer, J. Hoflack, 1994, Trends in pharmacological sciences.

Intramolecular diels-alder reaction with furan-diene. Comparison of reactivity and stereoselectivity within a set of structurally related substrates of

G. Chiari, G. Appendino, J. Hoflack, 1988 .

Three-dimensional structure of G protein-coupled receptors: from speculations to facts

S. Trumpp-Kallmeyer, B. Mouillac, J. Hoflack, 1996 .

Recognition site mapping and receptor modelling: Application to 5-HT receptors

J. Hoflack, M. Hibert, A. Bruinvels, 1991, Neurochemistry International.

Development of small macrocyclic kinase inhibitors.

P. Dijke, J. Hoflack, G. Sánchez-Duffhues, 2022, Future medicinal chemistry.

Functional architecture of vasopressin/oxytocin receptors.

J Hoflack, N. Cotte, S. Trumpp-Kallmeyer, 1999, Journal of receptor and signal transduction research.

1H‐NMR study of endothelin, sequence‐specific assignment of the spectrum and a solution structure

V. Saudek, J. Hoflack, J. Pelton, 1989, FEBS letters.

REALISIS: A Medicinal Chemistry-Oriented Reagent Selection, Library Design, and Profiling Platform

Jan Hoflack, Michael F. M. Engels, Theo Thielemans, 2004, J. Chem. Inf. Model..

Three-dimensional models of neuropeptide G-protein coupled receptors

S. Trumpp-Kallmeyer, J. Hoflack, M. Hibert, 1994, Neuropeptides.

Solution conformation of endothelin-3 by 1H NMR and distance geometry calculations

V. Saudek, J. Hoflack, J. Pelton, 1991, Neurochemistry International.

Solution structure of salmon calcitonin

V. Saudek, J. Hoflack, Jean-Philippe Meyer, 1991, Biopolymers.

Identification of a Single Residue Responsible for Agonist Selectivity in the Oxytocin‐Vasopressin Receptors

M. Manning, B. Mouillac, J. Hoflack, 1997 .