R. Macgregor

发表

Glucose Metabolic Rate Kinetic Model Parameter Determination in Humans: The Lumped Constants and Rate Constants for [18F]Fluorodeoxyglucose and [11C]Deoxyglucose

C. D. Arnett, A. Alavi, M. Reivich, 1985, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Use of 2-Deoxy-D[1-11C]Glucose for the Determination of Local Cerebral Glucose Metabolism in Humans: Variation within and between Subjects

Y Yonekura, D Christman, A. Alavi, 1982, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Effects of Blood Flow on [11C]Raclopride Binding in the Brain: Model Simulations and Kinetic Analysis of PET Data

N. Volkow, Gene-Jack Wang, J. Fowler, 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Measuring age-related changes in dopamine D2 receptors with 11C-raclopride and 18F-N-methylspiroperidol

N. Volkow, Gene-Jack Wang, A. Wolf, 1996, Psychiatry Research: Neuroimaging.

Metabolic trapping as a principle of oradiopharmaceutical design: some factors resposible for the biodistribution of [18F] 2-deoxy-2-fluoro-D-glucose.

A. Wolf, J. Fowler, N. Gutterson, 1978, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Mapping human brain monoamine oxidase A and B with 11C-labeled suicide inactivators and PET.

C. D. Arnett, A. Wolf, J. Fowler, 1987, Science.

Brain monoamine oxidase A inhibition in cigarette smokers.

N. Volkow, Gene-Jack Wang, A. Wolf, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [N-11C-Methyl]-(−)-Cocaine PET Studies in Human Subjects

David J. Schlyer, Fowler, Bernard Bendriem, 1990, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Inhibition of monoamine oxidase B in the brains of smokers

N. Volkow, Gene-Jack Wang, A. Wolf, 1996, Nature.

A FLUORINATED GLUCOSE ANALOG, 2‐FLUORO-2‐DEOXY-D‐GLUCOSE (F‐18): NONTOXIC TRACER FOR RAPID TUMOR DETECTION

J S Fowler, R R MacGregor, H. Atkins, 1980, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

A synthesis of 2-deoxy-D-[1-11C]glucose for regional metabolic studies: concise communication.

A. Wolf, J. Fowler, R. Macgregor, 1981, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Neuropharmacological actions of cigarette smoke: brain monoamine oxidase B (MAO B) inhibition.

N. Volkow, Gene-Jack Wang, A. Wolf, 1998, Journal of addictive diseases.

Alcohol intoxication does not change [11C]cocaine pharmacokinetics in human brain and heart.

N. Volkow, A. Wolf, J. Fowler, 1992, Synapse.

Alcohol inoxication does not change [11C]cocaine pharmacokinetics in human brain and heart

N. Volkow, Gene-Jack Wang, A. Wolf, 1992 .

Is [l-nC]Putrescine Useful as a Brain Tumor Marker?

A. Wolf, J. Fowler, J. Logan, 2006 .

Positron emission tomography study of human prostatic adenocarcinoma using carbon-11 putrescine.

N. Volkow, A. Wolf, J. Fowler, 1994, Nuclear medicine and biology.

A shielded synthesis system for production of 2-deoxy-2-[18F]fluoro-D-glucose.

A. Wolf, J. Fowler, R. Macgregor, 1981, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Positron emission tomography (PET) studies of dopaminergic/cholinergic interaction in the baboon brain

N. Volkow, J. Brodie, A. Wolf, 1990, Synapse.

Serial [18F]N-methylspiroperidol PET studies to measure changes in antipsychotic drug D-2 receptor occupancy in schizophrenic patients

C. D. Arnett, J. Brodie, A. Wolf, 1988, Biological Psychiatry.

Evidence that gingko biloba extract does not inhibit MAO A and B in living human brain.

N. Volkow, Gene-Jack Wang, J. Fowler, 2000, Life sciences.

[11C]spiroperidol: synthesis, specific activity determination, and biodistribution in mice.

A. Wolf, J. Fowler, C. Arnett, 1982, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Rapid Stereoselective Hydrolysis of (+)‐Cocaine in Baboon Plasma Prevents Its Uptake in the Brain: Implications for Behavioral Studies

J. Fowler, D. Schlyer, R. Macgregor, 1990, Journal of neurochemistry.

Gas‐liquid chromatographic determination of relative amounts of 2‐deoxy‐2‐flouro‐D‐glucose and 2‐deoxy‐2‐fluoro‐D‐mannose synthesized from various methods

A. Wolf, J. Fowler, D. Alexoff, 1985 .

Comparison of two PET radioligands for imaging extrastriatal dopamine receptorsin the human brain

N. Volkow, Gene-Jack Wang, A. Wolf, 1993, Synapse.

Specific Binding of [11C]Spiroperidol in Rat Brain In Vivo

C. D. Arnett, A. Wolf, J. Fowler, 1983, Journal of neurochemistry.

Mapping brain neuroleptic receptors in the live baboon.

A. Wolf, J. Fowler, J. Logan, 1984, Biological psychiatry.

Alcohol and immune defense.

R. Macgregor, 1986, JAMA.

Synthesis of 15O-labeled butanol via organoborane chemistry.

J. Fowler, R. Macgregor, G. Kabalka, 1985, The International journal of applied radiation and isotopes.

of Human Brain MA 0 B After L-Deprenyl ( Selegeline ) Withdrawal

N. Volkow, Gene-Jack Wang, A. Wolf, 2004 .

Visualization of monoamine oxidase in human brain.

N. Volkow, J. Fowler, G. Wang, 1996, Advances in pharmacology.

A new improved synthesis of 2-deoxy-2-[18F]fluoro-d-glucose from 18F-labeled acetyl hypofluorite.

A. Wolf, J. Fowler, R. Macgregor, 1982, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Distribution of 18F-5-fluorouracil in tumor-bearing mice and rats.

H. Atkins, A. Wolf, J. Fowler, 1978, International journal of nuclear medicine and biology.

Studies with Differentially Labeled [11C]Cocaine, [11C]Norcocaine, [11C]Benzoylecgonine, and [11C]‐and 4′‐[18F]Fluorococaine to Probe the Extent to Which [11C]Cocaine Metabolites Contribute to PET Images of the Baboon Brain

N. Volkow, A. Wolf, J. Fowler, 1994, Journal of neurochemistry.

Fluorine-18-N-methylspiroperidol: radiolytic decomposition as a consequence of high specific activity and high dose levels.

A. Wolf, J. Fowler, D. Schlyer, 1987, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-deprenyl and carbon-11-deprenyl-D2 for MAO B mapping.

N. Volkow, C. Patlak, Gene-Jack Wang, 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Synthesis of suicide inhibitors of monoamine oxidase: Carbon‐11 labeled clorgyline, L‐deprenyl and D‐deprenyl

A. Wolf, B. Långström, C. Halldin, 1988 .

Serial PET studies of human cerebral malignancy with [1-11C]putrescine and [1-11C]2-deoxy-D-glucose.

N. Volkow, J. Brodie, A. Wolf, 1987, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Smoking a single cigarette does not produce a measurable reduction in brain MAO B in non-smokers.

N. Volkow, J. Fowler, G. Wang, 1999, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

An acute dose of nicotine does not inhibit MAO B in baboon brain in vivo.

N. Volkow, J. Fowler, J. Logan, 1998, Life sciences.

Serotonin 5-HT2 receptor availability in chronic cocaine abusers.

N. Volkow, A. Wolf, A. Gjedde, 1995, Life sciences.

Species differences in [11C]clorgyline binding in brain.

C. D. Arnett, N. Volkow, J. Fowler, 2001, Nuclear medicine and biology.

Turnover of Brain Monoamine Oxidase Measured In Vivo by Positron Emission Tomography Using l‐[11C]Deprenyl

C. D. Arnett, A. Wolf, B. Långström, 1987, Journal of neurochemistry.

Synthesis of 3H- and 14C-labeled tracers for studies of functional monoamine oxidase activity

A. Wolf, B. Långström, C. Halldin, 1988 .

Evidence that L-deprenyl treatment for one week does not inhibit MAO A or the dopamine transporter in the human brain.

N. Volkow, J. Fowler, G. Wang, 2001, Life sciences.

Maintenance of brain monoamine oxidase B inhibition in smokers after overnight cigarette abstinence.

N. Volkow, J. Fowler, G. Wang, 2000, The American journal of psychiatry.

and Biodistributionin Mice

R. Macgregor, E. Norton, A. Wolf, 2006 .

GABAergic inhibition of endogenous dopamine release measured in vivo with 11C-raclopride and positron emission tomography

R R MacGregor, J D Brodie, J. Brodie, 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Monoamine oxidase: radiotracer development and human studies.

N. Volkow, Gene-Jack Wang, J. Fowler, 2000, Methods.

THE EFFECT OF TARGET-GAS PURITY ON THE CHEMICAL FORM OF 18F DURING 18F-F2 PRODUCTION USING THE NEON/FLUORINE TARGET

R. Ehrenkaufer, A. Wolf, J. Fowler, 1980, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Assessment of regional glucose metabolism in aging brain and dementia with positron-emission tomography

A. Alavi, M. Reivich, R. Dann, 1981 .

Nucleophilic aromatic substitution; kinetics of fluorine-18 substitution reactions in polyfluorobenzenes. Isotopic exchange between 18F− and polyfluorobenzenes in dimethylsulfoxide. A kinetic study

A. Wolf, R. Macgregor, F. Cacace, 1982 .

18F-5-Fluorouridine, a new probe for measuring the proliferation of tissue in vivo.

A. Wolf, J. Fowler, A. Goldin, 1982, Advances in enzyme regulation.

A direct comparison of the brain uptake and plasma clearance of N-[11C]methylspiroperidol and [18F]N-methylspiroperidol in baboon using PET.

C. D. Arnett, A. Wolf, B. Långström, 1986, International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology.

Selective, irreversible in vivo binding of [11C]clorgyline and [11C]-L-deprenyl in mice: potential for measurement of functional monoamine oxidase activity in brain using positron emission tomography.

J S Fowler, R R MacGregor, C. D. Arnett, 1985, Biochemical pharmacology.

Probing the biochemical basis of the PET image. Mechanistic PET studies of [11C]L-deprenyl binding using the deuterium isotope effect

A. Wolf, B. Långstrom, J. Fowler, 1989 .

Evaluation of radiorespirometry for the determination of monoamine oxidase activity in vivo utilizing [11C]octylamine as a substrate.

A. Wolf, J. Fowler, R. Macgregor, 1977, Biochemical pharmacology.

Carbon-11 labeled aliphatic amines in lung uptake and metabolism studies: potential for dynamic measurements in vivo.

A. Wolf, J. Fowler, R. Macgregor, 1976, The Journal of pharmacology and experimental therapeutics.

Decarbonylation of aroyl fluorides using Wilkinson's catalyst: a reevaluation

A. Wolf, R. Macgregor, R. Ehrenkaufer, 1982 .

Synthesis of (18F)Perchloryl Fluoride and its Reactions with Functionalized Aryl Lithiums

R. Macgregor, R. Ehrenkaufer, 1983 .

Anhydrous F-18 labeled eslemental flurine for radiopharmaceutical preparation.

R R MacGregor, T J Ruth, T Ido, 1980, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Synthesis and evaluation of fluorinated derivatives of fentanyl as candidates for opiate receptor studies using positron emission tomograpry

E. J. Simon, A. Wolf, D. Hwang, 1986 .

Mapping of functional activity in brain with 18F-fluoro-deoxyglucose.

A. Rosenquist, A. Alavi, M. Reivich, 1981, Seminars in nuclear medicine.

Synthesis of β‐Lactams and β‐Aminoesters via High Intensity Ultrasound‐Promoted Reformatsky Reactions.

R. Macgregor, R. Bartsch, N. A. Ross, 2004 .

Synthesis of β-lactams and β-aminoesters via high intensity ultrasound-promoted Reformatsky reactions

R. Macgregor, R. Bartsch, N. A. Ross, 2004 .

Radiopharmaceuticals. 16. Halogenated dopamine analogs. Synthesis and radiolabeling of 6-iododopamine and tissue distribution studies in animals.

H. Atkins, A. Wolf, J. Fowler, 1976, Journal of medicinal chemistry.

Radiopharmaceuticals. 12. A new rapid synthesis of carbon-11 labeled norepinephrine hydrochloride.

H. Atkins, A. Wolf, J. Fowler, 1974, Journal of medicinal chemistry.

A simple one-pot synthesis of cyclopropane [11C]carbonyl chloride. Synthesis and biodistribution of [11C]cyclorphan†

C. D. Arnett, A. Wolf, D. Hwang, 1986 .

Synthesis and preliminary evaluation in animals of carrier-free 11C-1-dopamine hydrochloride: X.

H. Atkins, A. Wolf, J. Fowler, 1973, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Radiopharmaceuticals XXVII. 18F-labeled 2-deoxy-2-fluoro-d-glucose as a radiopharmaceutical for measuring regional myocardial glucose metabolism in vivo: tissue distribution and imaging studies in animals.

J S Fowler, R R MacGregor, D E Kuhl, 1977, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Effects of central cholinergic blockade on striatal dopamine release measured with positron emission tomography in normal human subjects.

J S Fowler, R R MacGregor, J D Brodie, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Mapping muscarinic receptors in human and baboon brain using [N‐11C‐methyl]‐benztropine

N. Volkow, J. Brodie, A. Wolf, 1990, Synapse.

Synthesis of carbon-11 labeled iodinated cocaine derivatives and their distribution in baboon brain measured using positron emission tomography.

A. Wolf, J. Fowler, D. Schlyer, 1992, Journal of medicinal chemistry.

Localization of monoamine oxidase B in human brain by autoradiographical use of11C-labelled L-deprenyl

B. Långström, C. Halldin, S. Aquilonius, 2005, Journal of Neural Transmission.

Comparative PET studies of the kinetics and distribution of cocaine and cocaethylene in baboon brain

N. Volkow, A. Wolf, J. Fowler, 1992, Synapse.

Comparison of two pet radioligands for imaging extrastriatal dopamine transporters in human brain.

N. Volkow, A. Wolf, J. Fowler, 1995, Life sciences.

Tissue distributions of radiopharmaceuticals labeled with positron emitters and problems in relating them to human studies

A. Wolf, J. Fowler, D. Christman, 1983 .

Modular automation in PET tracer manufacturing: application of an autosynthesizer to the production of 2-deoxy-2-[18F]fluoro-D-glucose.

D L Alexoff, J A Russell, C Y Shiue, 1986, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Mapping cocaine binding sites in human and baboon brain in vivo

Bernard Bendriem, Jean Logan, Joanna S. Fowler, 1989, Synapse.

Imaging endogenous dopamine competition with [11C]raclopride in the human brain

Jean Logan, Jeffrey Lieberman, Joanna S. Fowler, 1994, Synapse.

Mechanistic Positron Emission Tomography Studies: Demonstration of a Deuterium Isotope Effect in the Monoamine Oxidase‐Catalyzed Binding of [11C]l‐Deprenyl in Living Baboon Brain

A. Wolf, B. Långstrom, J. Fowler, 1988, Journal of neurochemistry.

Cocaine Uptake Is Decreased in the Brain of Detoxified Cocaine Abusers

Nora D. Volkow, Jean Logan, Joanna S. Fowler, 1996, Neuropsychopharmacology.

Evaluation of age-related changes in serotonin 5-HT2 and dopamine D2 receptor availability in healthy human subjects.

J S Fowler, R R MacGregor, N. Volkow, 1995, Life sciences.

Decreased dopamine transporters with age in healthy human subjects

J S Fowler, N. Volkow, Gene-Jack Wang, 1994, Annals of neurology.

Distribution and kinetics of carbon-11-cocaine in the human body measured with PET.

J S Fowler, N. Volkow, A. Wolf, 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Quantitative autoradiography with radiopharmaceuticals, Part 2: Applications in radiopharmaceutical research: concise communication.

J S Fowler, R R MacGregor, Y Yonekura, 1983, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Pet studies of cocaine inhibition of myocardial norepinephrine uptake

N. Volkow, A. Wolf, J. Fowler, 1994, Synapse.

Reproducibility of repeated measures of deuterium substituted [11C]L-deprenyl ([11C]L-deprenyl-D2) binding in the human brain.

J S Fowler, R R MacGregor, N. Volkow, 2000, Nuclear medicine and biology.

N. Volkow, Gene-Jack Wang, J. Fowler, 1997, Neurobiology of Aging.

Positron Emission Tomography in the Study of Aging and Senile Dementia

B. Reisberg, M. Leon, A. Wolf, 1980, Neurobiology of Aging.

Opioid receptor imaging and displacement studies with [6-O-[11C] methyl]buprenorphine in baboon brain.

I. Galynker, J. Brodie, A. Wolf, 1996, Nuclear medicine and biology.

Monoamine oxidase B (MAO B) inhibitor therapy in Parkinson's disease

N. Volkow, A. Wolf, J. Fowler, 1993, Neurology.

Carbon-11-cocaine binding compared at subpharmacological and pharmacological doses: a PET study.

J S Fowler, R R MacGregor, N. Volkow, 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

PET imaging of monoamine oxidase B in peripheral organs in humans.

N. Volkow, Gene-Jack Wang, J. Fowler, 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Reproducibility of repeated measures of carbon-11-raclopride binding in the human brain.

J S Fowler, N. Volkow, Gene-Jack Wang, 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Regional cerebral glucose metabolism in aging and senile dementia as determined by 18F-deoxyglucose and positron emission tomography.

A. Alavi, M. Reivich, R. Dann, 1982, Experimental brain research.

Increased accumulation of 2-deoxy-2-[18F]Fluoro-D-glucose in liver metastases from colon carcinoma.

J S Fowler, R R MacGregor, Y Yonekura, 1982, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Regional distribution and kinetics of haloperidol binding in human brain: A pet study with [18F]haloperidol

N. Volkow, A. Alavi, J. Brodie, 1992, Synapse.

N. Volkow, J. Fowler, D. Schlyer, 1990, Journal of neuroscience research.

ANHYDROUS 18F LABELED ELEMENTAL FLUORINE FOR RADIOPHARMACEUTICAL PREPARATION

A. Wolf, J. Fowler, R. Macgregor, 1981 .

Color-blind fluorescence detection for four-color DNA sequencing.

Lori A Burns, Carter Kittrell, Freddy T. Nguyen, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Improved delineation of human dopamine receptors using [18F]-N-methylspiroperidol and PET.

A. Wolf, J. Fowler, D. Christman, 1986, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Regional brain glucose metabolism in chronic schizophrenia. A positron emission transaxial tomographic study.

J. Brodie, A. Wolf, J. Fowler, 1984, Archives of general psychiatry.

RADIOPHARMACEUTICALS PART 12, A NEW RAPID SYNTHESIS OF CARBON-11 LABELED NOREPINEPHRINE HYDROCHLORIDE

H. Atkins, A. Wolf, J. Fowler, 1974 .

Monoamine oxidase: radiotracer development and human studies.

Gene-Jack Wang, J. Logan, R. Macgregor, 2002 .

Monoamine oxidase: radiotracer development and human studies.

N. Volkow, Gene-Jack Wang, J. Fowler, 2000, Methods.

METABOLIC TRAPPING AS A PRINCIPLE OF RADIO-PHARMACEUTICAL DESIGN: SOME FACTORS RESPONSIBLE FOR THE BIODISTRIBUTION OF 18F-2-DEOXY-2-FLUORO-D-GLUCOSE

A. Wolf, J. Fowler, N. Gutterson, 1979 .

Synthesis of 11C-compounds including double isotopic labelling: Some perspectives

A. Wolf, G. Antoni, A. Gee, 1988 .