Oguz Kanca

发表

Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila

H. Bellen, F. Schnorrer, Oguz Kanca, 2017, Genetics.

Loss-of-function in IRF2BPL is associated with neurological phenotypes

Henry J. Lin, Rebecca C. Spillmann, Michael F. Wangler, 2018, bioRxiv.

Drosophila functional screening of de novo variants in autism uncovers deleterious variants and facilitates discovery of rare neurodevelopmental diseases

Michael F. Wangler, Nele A. Haelterman, Jill A. Madden, 2021, bioRxiv.

Lipid Microdomain Clustering Induces a Redistribution of Antigen Recognition and Adhesion Molecules on Human T Lymphocytes1

Jason S. Mitchell, Oguz Kanca, B. McIntyre, 2002, The Journal of Immunology.

Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling

N. C. Yeo, Undiagnosed Diseases Network, S. Nelson, 2022, Science advances.

This information is current as Lymphocytes Adhesion Molecules on Human T Redistribution of Antigen Recognition and Lipid Microdomain Clustering Induces a

Jason S. Mitchell, Oguz Kanca, B. McIntyre, 2002 .

De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia.

Matthew H. Brush, Gabor T. Marth, John Arul Phillips, 2019, American journal of human genetics.

An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms

N. Perrimon, A. Spradling, Yanhui Hu, 2019, bioRxiv.

Gene Tagging Strategies To Assess Protein Expression, Localization, and Function in Drosophila

H. Bellen, F. Schnorrer, Oguz Kanca, 2017, Genetics.

The recurrent de novo c.2011C>T missense variant in MTSS2 causes syndromic intellectual disability.

H. Bellen, K. Boycott, K. Kernohan, 2022, American journal of human genetics.

TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila.

Michael F. Wangler, Q. K. Tan, R. Pfundt, 2021, American journal of human genetics.

De novo mutations in TOMM70, a receptor of the mitochondrial import translocase, cause neurological impairment.

Michael F. Wangler, Undiagnosed Diseases Network, A. Vanderver, 2020, Human molecular genetics.

A cellular process that includes asymmetric cytokinesis remodels the dorsal tracheal branches in Drosophila larvae

M. Affolter, A. Denes, Oguz Kanca, 2015, Development.

Engineered kinases as a tool for phosphorylation of selected targets in vivo

M. Affolter, M. Vigano, Oguz Kanca, 2022, The Journal of cell biology.

The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer

Daryl M. Gohl, M. Affolter, A. Denes, 2015, G3: Genes, Genomes, Genetics.

an essential apterous wing enhancer

Daryl M. Gohl, M. Affolter, A. Denes, 2015 .

Drosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases

Michael F. Wangler, Nele A. Haelterman, Jill A. Madden, 2022, Cell reports.

IRF2BPL Is Associated with Neurological Phenotypes.

Henry J. Lin, Rebecca C. Spillmann, Michael F. Wangler, 2018, American journal of human genetics.

A gene-specific T2A-GAL4 library for Drosophila

N. Perrimon, A. Spradling, Yanhui Hu, 2018, eLife.

Fluorescent fusion protein knockout mediated by anti-GFP nanobody

M. Affolter, Oguz Kanca, E. Caussinus, 2011, Nature Structural &Molecular Biology.

In vivo regulation of fluorescent fusion proteins by engineered kinases

M. Affolter, Oguz Kanca, Clemens Cabernard, 2021, bioRxiv.

Establishment of a Developmental Compartment Requires Interactions between Three Synergistic Cis-regulatory Modules

Daryl M. Gohl, Matthew Slattery, Fisun Hamaratoglu, 2015, PLoS genetics.

A gene-specific T 2 AGAL 4 library for Drosophila 1

Verena, N. Perrimon, A. Spradling, 2018 .

Raeppli: a whole-tissue labeling tool for live imaging of Drosophila development

Markus Affolter, Oguz Kanca, M. Affolter, 2014, Development.

An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila

Oguz Kanca, David Li-Kroeger, Pei-Tseng Lee, 2018, bioRxiv.

Drosophila as a diet discovery tool for treating amino acid disorders

M. Piper, H. Bellen, J. Christodoulou, 2022, Trends in Endocrinology & Metabolism.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

N. Perrimon, Yanhui Hu, R. Levis, 2021, bioRxiv.

IRF2BPL Is Associated with Neurological Phenotypes.

Henry J. Lin, Rebecca C. Spillmann, Michael F. Wangler, 2018, American journal of human genetics.

De Novo Variants in MRTFB have gain of function activity in Drosophila and are associated with a novel neurodevelopmental phenotype with dysmorphic features

Ellen F. Macnamara, Michael F. Wangler, H. Bellen, 2022, bioRxiv.

Heterozygous loss-of-function variants significantly expand the phenotypes associated with loss of GDF11

Sharyn A. Lincoln, Michael F. Wangler, J. Rosenfeld, 2021, Genetics in Medicine.

De novo FZR1 loss-of-function variants cause developmental and epileptic encephalopathies including Myoclonic Atonic Epilepsy

H. Mefford, H. Bellen, Shinya Yamamoto, 2021, medRxiv.

IV. Tools and methods for studying cell migration and cell rearrangement in tissue and organ development.

M. Affolter, Oguz Kanca, Amanda Ochoa-Espinosa, 2014, Methods.

Very-long-chain fatty acids induce glial-derived sphingosine-1-phosphate synthesis, secretion, and neuroinflammation.

S. G. Tattikota, H. Bellen, Oguz Kanca, 2023, Cell metabolism.

Loss of Mitochondrial Enoyl CoA Reductase causes elevated ceramide levels and impairs iron metabolism

M. Wheeler, H. Bellen, J. Kohler, 2023, bioRxiv.

Bi-allelic variants in INTS11 are associated with a complex neurological disorder.

William E. Byrd, Marni J. Falk, Mahshid S. Azamian, 2023, American journal of human genetics.

La CaSSA da Drosophila: A Versatile Expansion of the Tool Box

Oguz Kanca, Hugo J. Bellen, H. Bellen, 2019, Neuron.

Protein Knockouts in Living Eukaryotes Using deGradFP and Green Fluorescent Protein Fusion Targets

M. Affolter, Oguz Kanca, E. Caussinus, 2013, Current protocols in protein science.

Use of the CRISPR‐Cas9 System in Drosophila Cultured Cells to Introduce Fluorescent Tags into Endogenous Genes

N. Perrimon, Yanhui Hu, H. Bellen, 2020, Current protocols in molecular biology.

Systematic expression profiling of dprs and DIPs reveals cell surface codes in Drosophila larval peripheral neurons

Robert A. Carrillo, H. Bellen, Oguz Kanca, 2021, bioRxiv.

Integrating non-mammalian model organisms in the diagnosis of rare genetic diseases in humans

Michael F. Wangler, H. Bellen, M. Wangler, 2023, Nature reviews. Genetics.

A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

Michael F. Wangler, S. Celniker, K. Wan, 2023, Cell Reports.

De Novo Variants in WDR37 Are Associated with Epilepsy, Colobomas, Dysmorphism, Developmental Delay, Intellectual Disability, and Cerebellar Hypoplasia.

Michael F. Wangler, W. Chung, A. Fatemi, 2019, American journal of human genetics.

A defect in mitochondrial fatty acid synthesis impairs iron metabolism and causes elevated ceramide levels

M. Wheeler, H. Bellen, J. Kohler, 2023, Nature Metabolism.

Very-long-chain fatty acids induce glial-derived sphingosine-1-phosphate synthesis, secretion, and neuroinflammation.

S. G. Tattikota, H. Bellen, Oguz Kanca, 2023, Cell metabolism.

De novo and inherited variants in DDX39B cause a Novel Syndrome Characterized by Neurodevelopmental Delay, Short Stature, and Congenital Hypotonia

Michael F. Wangler, H. Bellen, Sharayu Jangam, 2023, medRxiv.

Systematic expression profiling of dprs and DIPs reveals cell surface codes in 1 Drosophila larval peripheral neurons 2 3

Robert A. Carrillo, H. Bellen, Oguz Kanca, 2021 .

De novo variants in EMC1 lead to neurodevelopmental delay and cerebellar degeneration and affect glial function in drosophila.

J. Lupski, H. Bellen, J. Fock, 2022, Human molecular genetics.

Rare de novo gain-of-function missense variants in DOT1L are associated with developmental delay and congenital anomalies.

Michael F. Wangler, C. Cytrynbaum, R. Weksberg, 2023, American journal of human genetics.

Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays

J. Pruneda, Oguz Kanca, D. Sweetser, 2023, eLife.

Allelic strengths of encephalopathy-associated UBA5 variants correlate between in vivo and in vitro assays

H. Bellen, J. Pruneda, Oguz Kanca, 2023, medRxiv.

A cellular process that includes asymmetric cytokinesis remodels the dorsal tracheal branches in Drosophila larvae

M. Affolter, A. Denes, Oguz Kanca, 2015, Development.

Systematic expression profiling of dprs and DIPs reveals cell surface codes in Drosophila larval motor and sensory neurons.

Robert A. Carrillo, H. Bellen, Oguz Kanca, 2022, Development.

De novo variants in FRYL are associated with developmental delay, intellectual disability, and dysmorphic features.

Denise G. Lanza, Jason D. Heaney, J. Posey, 2024, American journal of human genetics.

Identifying potential dietary treatments for inherited metabolic disorders using Drosophila nutrigenomics

Oguz Kanca, Sarah Mele, Jiayi Lin, 2024, Cell reports.

Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila

E. Verheyen, Oguz Kanca, Paul C. Marcogliese, 2024, Nature communications.

LymphocytesAdhesion Molecules on Human T Redistribution of Antigen Recognition and Lipid Microdomain Clustering Induces a

Oguz Kanca, Bradley W. McIntyre, Jason S. Mitchell, 2002 .

Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress.

Oguz Kanca, Julie Jacquemyn, Isha Ralhan, 2024, Nature neuroscience.