Ko-Fan Chen

发表

Functional genomics in Drosophila models of human disease.

Ko-Fan Chen, Damian C Crowther, Ko-Fan Chen, 2012, Briefings in functional genomics.

Nuclear Export of Drosophila PERIOD contributes to temperature compensation of the circadian clock

R. Stanewsky, Astrid V Giesecke, Deniz Top, 2021, bioRxiv.

Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance*

Shih-Chieh Lin, Ko-Fan Chen, S. Tsai, 2008, Journal of Biological Chemistry.

Neurocalcin regulates nighttime sleep and arousal in Drosophila

Ko-Fan Chen, J. Jepson, Angélique Lamaze, 2019, eLife.

Aberrant expression of leptin in human endometriotic stromal cells is induced by elevated levels of hypoxia inducible factor-1alpha.

Shih-Chieh Lin, Ko-Fan Chen, S. Tsai, 2007, The American journal of pathology.

Transcriptional repression of human cad gene by hypoxia inducible factor-1α

Ko-Fan Chen, S. Tsai, H. Sun, 2005, Nucleic acids research.

Neurocalcin acts in a clock- and light-modulated dopaminergic pathway to promote night sleep in Drosophila

Ko-Fan Chen, J. Jepson, P. Kratschmer, 2017 .

N eurocalcin acts in a clock-and light-modulated dopaminergic 1 pathway to promote night sleep in Drosophila 2

Ko-Fan Chen, J. Jepson, P. Kratschmer, 2017 .

A novel period mutation implicating nuclear export in temperature compensation of the Drosophila circadian clock

R. Stanewsky, Astrid V Giesecke, Deniz Top, 2022, Current Biology.

The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer’s disease

Ko-Fan Chen, Bernard Possidente, David A. Lomas, 2014, Disease Models & Mechanisms.

Novel mechanisms operating in the central pacemaker and in the light-synchronization pathway of Drosophila’s circadian clock

Ko-Fan Chen, 2011 .

A Role for the PERIOD:PERIOD Homodimer in the Drosophila Circadian Clock

E. Wolf, R. Stanewsky, Ko-Fan Chen, 2009, PLoS biology.

Light-Dependent Interactions between the Drosophila Circadian Clock Factors Cryptochrome, Jetlag, and Timeless

R. Stanewsky, Ko-Fan Chen, Nicolai Peschel, 2009, Current Biology.

Computational analysis and refinement of sequence structure on chromosome 22q11.2 region: application to the development of quantitative real-time PCR assay for clinical diagnosis.

Chung-Ming Chen, Ko-Fan Chen, S. Tsai, 2006, Genomics.

Central and peripheral circadian clocks and their role in Alzheimer's disease

Ko-Fan Chen, Damian C. Crowther, Ruchi Chauhan, 2017, Disease Models & Mechanisms.

Disrupted Glutamate Signaling in Drosophila Generates Locomotor Rhythms in Constant Light

C. Kyriacou, E. Rosato, Ko-Fan Chen, 2020, Frontiers in Physiology.

Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability

Edgar Buhl, R. Stanewsky, Ko-Fan Chen, 2016, Proceedings of the National Academy of Sciences.

K-F. (2016). Quasimodo mediates daily and acute light effects on Drosophila clock neuron excitability. Proceedings of the National Academy of Sciences of the United States of America, 113(47), 13486-13491. DOI: 10.1073/pnas.1606547113

Edgar Buhl, Ko-Fan Chen, James J. L. Hodge, 2016 .

CRYPTOCHROMES confer robustness, not rhythmicity, to circadian timekeeping

M. Putker, A. Sancar, K. Feeney, 2020, bioRxiv.

A Wake-Promoting Circadian Output Circuit in Drosophila

Ko-Fan Chen, Patrick Krätschmer, James E. C. Jepson, 2018, Current Biology.

The Drosophila dystonia gene homolog Neurocalcin facilitates sleep by inhibiting a movement-promoting neural network

Ko-Fan Chen, J. Jepson, Patrick Krätschmer, 2017, bioRxiv.

Impaired Pre‐Motor Circuit Activity and Movement in a Drosophila Model of KCNMA1‐Linked Dyskinesia

D. Kullmann, Edgar Buhl, A. Pittman, 2021, Movement disorders : official journal of the Movement Disorder Society.

Flyglow: Single-fly observations of simultaneous molecular and behavioural circadian oscillations in controls and an Alzheimer’s model

J. O’Neill, Ko-Fan Chen, D. Crowther, 2016, Scientific Reports.

Simultaneous Monitoring of Behavior & Peripheral Clocks in Drosophila Reveals Unstructured Sleep in an Alzheimer’s Model

J. O’Neill, Ko-Fan Chen, D. Crowther, 2015, bioRxiv.

QUASIMODO, a Novel GPI-Anchored Zona Pellucida Protein Involved in Light Input to the Drosophila Circadian Clock

R. Závodská, H. Sehadová, R. Stanewsky, 2011, Current Biology.

Prion protein stabilizes amyloid-β (Aβ) oligomers and enhances Aβ neurotoxicity in a Drosophila model of Alzheimer's disease

J. H. Viles, Ko-Fan Chen, D. Crowther, 2018, The Journal of Biological Chemistry.

Insights into amyloid disease from fly models.

Ko-Fan Chen, D. Crowther, 2014, Essays in biochemistry.

Expression of Sex-Determining Genes in the Scalp of Men with Androgenetic Alopecia

C. Zouboulis, Ko-Fan Chen, S. Tsai, 2007, Dermatology.

Expression of sex‐determining genes in human sebaceous glands and their possible role in the pathogenesis of acne

C. Zouboulis, Ko-Fan Chen, S. Tsai, 2006, Journal of the European Academy of Dermatology and Venereology : JEADV.

Neurocalcin regulates nighttime sleep and arousal in Drosophila

Ko-Fan Chen, J. Jepson, Simon A. Lowe, 2019, eLife.

A knock-in Drosophila model supports a conserved link between potassium channelopathy and involuntary movement

D. Kullmann, Edgar Buhl, Ko-Fan Chen, 2020, bioRxiv.