E. Rempel

发表

Decoding the regulatory logic of the Drosophila male stem cell system

M. Boutros, J. Lohmann, Juliane Mundorf, 2017, bioRxiv.

Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests

J. Rahnenführer, J. Hengstler, M. Leist, 2016, Archives of Toxicology.

RNA-Based Detection of Gene Fusions in Formalin-Fixed and Paraffin-Embedded Solid Cancer Samples

P. Schirmacher, A. Stenzinger, D. Kazdal, 2019, Cancers.

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

Nils Blüthgen, Tanja Waldmann, Jan G. Hengstler, 2015, Archives of Toxicology.

Spatial and temporal heterogeneity of panel-based tumor mutational burden (TMB) in pulmonary adenocarcinoma: separating biology from technical artifacts.

S. Fröhling, M. Kriegsmann, A. Warth, 2019, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Harmonization and Standardization of Panel-Based Tumor Mutational Burden (TMB) Measurement: Real-World Results and Recommendations of the QuIP Study.

S. Fröhling, M. Tiemann, W. Weichert, 2020, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Quantifying potential confounders of panel-based tumor mutational burden (TMB) measurement.

S. Fröhling, W. Weichert, P. Schirmacher, 2020, Lung cancer.

Motor neurons control blood vessel patterning in the developing spinal cord

Robert Luck, E. Rempel, O. Ermakova, 2017, Nature Communications.

Subclassification, survival prediction and drug target analyses of chemotherapy-naïve muscle-invasive bladder cancer with a molecular screening

A. Hartmann, M. Eckstein, P. Erben, 2018, Oncotarget.

Pan-cancer analysis of genomic scar patterns caused by homologous repair deficiency (HRD)

S. Fröhling, D. Kazdal, J. Budczies, 2022, npj Precision Oncology.

Conventional and semi-automatic histopathological analysis of tumor cell content for multigene sequencing of lung adenocarcinoma

M. Kriegsmann, J. Kriegsmann, R. Longuespée, 2021, Translational lung cancer research.

Decoding the Regulatory Logic of the Drosophila Male Stem Cell System.

M. Boutros, J. Lohmann, Juliane Mundorf, 2018, Cell reports.

Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis

J. Rahnenführer, J. Hengstler, C. Cadenas, 2016, Archives of Toxicology.

EDI3 links choline metabolism to integrin expression, cell adhesion and spreading

J. Rahnenführer, J. Hengstler, E. Rempel, 2014, Cell adhesion & migration.

Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases

Olaf Neumann, Michael Thomas, Ivo Buchhalter, 2019, International journal of cancer.

From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects

Michael R. Berthold, Raivo Kolde, Tanja Waldmann, 2014, Archives of Toxicology.

Glycerol-3-phosphate Acyltransferase 1 Promotes Tumor Cell Migration and Poor Survival in Ovarian Carcinoma.

J. Rahnenführer, K. Edlund, J. Hengstler, 2017, Cancer research.

Variant classification in precision oncology

Melanie Boerries, Olaf Neumann, Michael Thomas, 2019, International journal of cancer.

Optimizing panel-based tumor mutational burden (TMB) measurement.

S. Fröhling, P. Schirmacher, A. Stenzinger, 2019, Annals of oncology : official journal of the European Society for Medical Oncology.

Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels

Olaf Neumann, Michael Thomas, Ivo Buchhalter, 2019, International journal of cancer.

Size matters: Dissecting key parameters for panel‐based tumor mutational burden analysis

Olaf Neumann, Michael Thomas, Ivo Buchhalter, 2018, International journal of cancer.

Implementing tumor mutational burden (TMB) analysis in routine diagnostics-a primer for molecular pathologists and clinicians.

Olaf Neumann, Michael Thomas, Jan Budczies, 2018, Translational lung cancer research.

Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

M. Schmid, J. Lohmann, Anne Pfeiffer, 2016, eLife.

Targeting rare and non-canonical driver variants in NSCLC - An uncharted clinical field.

S. Fröhling, M. Kriegsmann, P. Schirmacher, 2021, Lung cancer.

Toxicogenomics directory of chemically exposed human hepatocytes

R. Stierum, G. Myatt, J. Rahnenführer, 2014, Archives of Toxicology.

Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells

Raivo Kolde, Tanja Waldmann, Jan G. Hengstler, 2014, Chemical research in toxicology.

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

Hedi Peterson, Daniel Gerhard, Raivo Kolde, 2012, Archives of Toxicology.

Immune cell recruitment in teratomas is impaired by increased Wnt secretion.

M. Boutros, E. Rempel, I. Augustin, 2016, Stem cell research.

Subtype specific expression and survival prediction of pivotal lncRNAs in muscle invasive bladder cancer

A. Hartmann, P. Erben, C. Bolenz, 2020, Scientific Reports.

YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis

P. Schirmacher, D. Kazdal, N. Gretz, 2020, Cancer Research.

Optimizing panel-based tumor mutational burden (TMB) measurement.

S. Fröhling, P. Schirmacher, A. Stenzinger, 2019, Annals of oncology : official journal of the European Society for Medical Oncology.

RSPO2 gene rearrangement: a powerful driver of β-catenin activation in liver tumours

A. Rosenwald, M. Kriegsmann, P. Schirmacher, 2019, Gut.

Immuno‐oncology gene expression profiling of formalin‐fixed and paraffin‐embedded clear cell renal cell carcinoma: Performance comparison of the NanoString nCounter technology with targeted RNA sequencing

P. Schirmacher, A. Stenzinger, D. Kazdal, 2020, Genes, chromosomes & cancer.

Stem Cell Transcriptome Responses and Corresponding Biomarkers That Indicate the Transition from Adaptive Responses to Cytotoxicity.

Tanja Waldmann, Anna-Katharina Holzer, Jan G Hengstler, 2017, Chemical research in toxicology.

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation.

Tanja Waldmann, Smita Jagtap, Marcel Leist, 2015, Journal of visualized experiments : JoVE.

The molecular signature of AML with increased ALDH activity suggests a stem cell origin

V. Beneš, A. Trumpp, S. Raffel, 2018, Leukemia & lymphoma.

Toxicogenomics directory of chemically exposed human hepatocytes

R. Stierum, G. Myatt, J. Rahnenführer, 2014, Archives of Toxicology.

The molecular signature of AML with increased ALDH activity suggests a stem cell origin

V. Beneš, A. Trumpp, S. Raffel, 2018, Leukemia & lymphoma.

WEADE: A workflow for enrichment analysis and data exploration

Michael Boutros, Nils Trost, Eugen Rempel, 2018, bioRxiv.