D. Skalnik

发表

Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.

Adrian Bird, Robert Andrews, Robert S. Illingworth, 2012, Genes & development.

CCAAT displacement protein as a repressor of the myelomonocytic-specific gp91-phox gene promoter.

S. Orkin, D. Skalnik, E. Strauss, 1991, The Journal of biological chemistry.

Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut

S. Orkin, E. Neufeld, P. Lievens, 1992, Nature Genetics.

CpG-binding Protein Is a Nuclear Matrix- and Euchromatin-associated Protein Localized to Nuclear Speckles Containing Human Trithorax

Jeong-Heon Lee, D. Skalnik, Jeong‐Heon Lee, 2002, The Journal of Biological Chemistry.

The Human Immunodeficiency Virus Protease Inhibitor Ritonavir Inhibits Lung Cancer Cells, in Part, by Inhibition of Survivin

A. Srirangam, A. Rizzardi, D. Potter, 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Rbm15-Mkl1 Interacts with the Setd1b Histone H3-Lys4 Methyltransferase via a SPOC Domain That Is Required for Cytokine-Independent Proliferation

Jeong-Heon Lee, D. Skalnik, Jeong‐Heon Lee, 2012, PloS one.

Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558.

P. Newburger, E. Eklund, D. Skalnik, 1994, The Journal of clinical investigation.

Identification of the human HEX1/hExo1 gene promoter and characterization of elements responsible for promoter activity.

David M. Wilson, M. Kelley, P. Ladd, 2003, DNA repair.

The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis

H. HogenEsch, Jeong-Heon Lee, D. Skalnik, 2014, PloS one.

Simple and efficient identification of chromatin modifying complexes and characterization of complex composition.

D. Skalnik, Jeong Heon Lee, 2013, Methods in molecular biology.

CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.

Jeong-Heon Lee, D. Skalnik, J. S. Butler, 2008, DNA and cell biology.

Antisense Targeting of CXXC Finger Protein 1 Inhibits Genomic Cytosine Methylation and Primitive Hematopoiesis in Zebrafish*

D. Skalnik, J. Marrs, Suzanne R. L. Young, 2006, Journal of Biological Chemistry.

Efficient differentiation of murine embryonic stem cells requires the binding of CXXC finger protein 1 to DNA or methylated histone H3-Lys4.

D. Skalnik, J. Mahadevan, 2016, Gene.

Dynamic Loss of H2B Ubiquitylation without Corresponding Changes in H3K4 Trimethylation during Myogenic Differentiation

B. Dynlacht, Christopher Bowman, Jeong-Heon Lee, 2012, Molecular and Cellular Biology.

Uhrf 1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd 1 a

Jonghwan Kim, Bilal Cakir, Yangfei Xiang, 2018 .

CCAAT Displacement Protein Competes with Multiple Transcriptional Activators for Binding to Four Sites in the Proximal gp91phox Promoter*

W. Luo, D. Skalnik, 1996, The Journal of Biological Chemistry.

CXXC finger protein 1 is required for normal proliferation and differentiation of the PLB-985 myeloid cell line.

D. Skalnik, Suzanne R. L. Young, 2007, DNA and cell biology.

PAGE separation of hemi-methylated or unmethylated oligonucleotide substrates to distinguish between maintenance and de novo DNA methyltranferase activity.

Jeong-Heon Lee, D. Skalnik, J. S. Butler, 2006, Journal of biochemical and biophysical methods.

Restriction of neuroblastoma to the prostate gland in transgenic mice

S. Orkin, D. Dorfman, D. Skalnik, 1991, Molecular and cellular biology.

The nucleotide sequence of Syrian hamster HMG-CoA reductase cDNA.

D. Skalnik, R. D. Simoni, 1985, DNA.

Interferon Regulatory Factor-2 Directs Transcription from the gp91phox Promoter*

W. Luo, D. Skalnik, 1996, The Journal of Biological Chemistry.

Characterization of a gp91-phox Promoter Element That Is Required for Interferon γ-induced Transcription (*)

D. Skalnik, E. Eklund, 1995, The Journal of Biological Chemistry.

Epigenetic regulator Cfp1 safeguards male meiotic progression by regulating meiotic gene expression

Y. Okada, D. Skalnik, Ho-Geun Yoon, 2022, Experimental & Molecular Medicine.

CCAAT displacement protein, a regulator of differentiation-specific gene expression, binds a negative regulatory element within the 5' end of the human papillomavirus type 6 long control region

D. Skalnik, S. Pattison, A. Roman, 1997, Journal of virology.

DNA-binding properties of CCAAT displacement protein cut repeats.

W. Luo, D. Skalnik, D. Catt, 1999, Cellular and molecular biology.

Targeting of transgene expression to monocyte/macrophages by the gp91-phox promoter and consequent histiocytic malignancies.

S. Orkin, N. Copeland, N. Jenkins, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Transcriptional mechanisms regulating myeloid-specific genes.

D. Skalnik, 2002, Gene.

Sequence-specific binding of HMG-I (Y) to the proximal promoter of the gp91-phox gene.

E. Neufeld, D. Skalnik, 1992, Biochemical and biophysical research communications.

Identification of a minimal cis-element and cognate trans-factor(s) required for induction of Rac2 gene expression during K562 cell differentiation.

D. Skalnik, R. Muthukrishnan, 2009, Gene.

CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin

D. Skalnik, C. Tate, Jeong‐Heon Lee, 2010, The FEBS journal.

Wdr82 Is a C-Terminal Domain-Binding Protein That Recruits the Setd1A Histone H3-Lys4 Methyltransferase Complex to Transcription Start Sites of Transcribed Human Genes

D. Skalnik, Jeong‐Heon Lee, 2007, Molecular and Cellular Biology.

Identification and Characterization of the Human Set1B Histone H3-Lys4 Methyltransferase Complex*

D. Skalnik, J. You, C. Tate, 2007, Journal of Biological Chemistry.

CpG-binding Protein (CXXC Finger Protein 1) Is a Component of the Mammalian Set1 Histone H3-Lys4 Methyltransferase Complex, the Analogue of the Yeast Set1/COMPASS Complex*

D. Skalnik, Jeong‐Heon Lee, 2005, Journal of Biological Chemistry.

Reduced Genomic Cytosine Methylation and Defective Cellular Differentiation in Embryonic Stem Cells Lacking CpG Binding Protein

D. Skalnik, D. Carlone, Suzanne R. L. Young, 2005, Molecular and Cellular Biology.

Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

Jonghwan Kim, Bilal Cakir, Yangfei Xiang, 2018, Nature Communications.

Histone deacetylase activity is required for embryonic stem cell differentiation

D. Skalnik, Jeong-Heon Lee, Suzanne R L Hart, 2004, Genesis.

Cloning and characterization of the gene encoding the mouse homologue of CpG binding protein.

P. Ladd, D. Skalnik, D. Carlone, 2002, Gene.

CpG Binding Protein Is Crucial for Early Embryonic Development

D. Skalnik, D. Carlone, D. L. Carlone, 2001, Molecular and Cellular Biology.

Embryonic Development CpG Binding Protein Is Crucial for Early

D. Skalnik, D. Carlone, 2001 .

Cloning of a Mammalian Transcriptional Activator That Binds Unmethylated CpG Motifs and Shares a CXXC Domain with DNA Methyltransferase, Human Trithorax, and Methyl-CpG Binding Domain Protein 1

B. Jacobsen, D. Skalnik, D. Carlone, 2000, Molecular and Cellular Biology.

Identification and Characterization of the DNA Binding Domain of CpG-binding Protein*

K. Voo, D. Skalnik, Jeong‐Heon Lee, 2001, The Journal of Biological Chemistry.

Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2

H. Kimura, G. Stewart, H. Kurumizaka, 2018, Molecular cell.

Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases*

M. Cosgrove, D. Skalnik, V. Dharmarajan, 2012, The Journal of Biological Chemistry.

Methyl group acceptance assay for the determination of global DNA methylation levels.

K. Nephew, C. Balch, D. Skalnik, 2009, Methods in molecular biology.

Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2

H. Kimura, G. Stewart, H. Kurumizaka, 2018, Molecular cell.

Title Histone Methylation by SETD 1 A Protects Nascent DNAthrough the Nucleosome Chaperone Activity of FANCD 2

H. Kimura, G. Stewart, H. Kurumizaka, 2018 .

Cfp 1 integrates both CpG content and gene activity for accurate H 3 K 4 me 3 deposition in embryonic stem cells

Robert S. Illingworth, A. Bird, R. Andrews, 2012 .

The epigenetic regulator Cfp1

D. Skalnik, 2010, Biomolecular concepts.

Overexpression of CCAAT Displacement Protein Represses the Promiscuously Active Proximal gp91phox Promoter

W. Luo, D. Skalnik, S. Hawkins, 1999 .

PHAGOCYTES Overexpression of CCAAT Displacement Protein Represses the Promiscuously Active Proximal gp 91

W. Luo, D. Skalnik, S. Hawkins, 1999 .

CCAAT Displacement Protein (CDP/Cut) Binds a Negative Regulatory Element in the Human Tryptophan Hydroxylase Gene

D. Skalnik, N. Teerawatanasuk, L. Carr, 1999, Journal of neurochemistry.

Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes*

M. Cosgrove, D. Skalnik, David G. Skalnik, 2016, The Journal of Biological Chemistry.

Cloning of a cDNA encoding a human DNA-binding protein similar to ribosomal protein S1.

S. W. Lee, E. Eklund, D. Skalnik, 1995, Gene.

Elf-1 and PU.1 induce expression of gp91(phox) via a promoter element mutated in a subset of chronic granulomatous disease patients.

K. Voo, D. Skalnik, 1999, Blood.

The Matrix Attachment Region-binding Protein SATB1 Interacts with Multiple Elements within the gp91 phox Promoter and Is Down-regulated during Myeloid Differentiation*

T. Kohwi-Shigematsu, D. Skalnik, S. Hawkins, 2001, The Journal of Biological Chemistry.

Characterization of three promoter elements and cognate DNA binding protein(s) necessary for IFN-gamma induction of gp91-phox transcription.

W. Luo, E. Eklund, D. Skalnik, 1996, Journal of immunology.

YY1 Binds Five cis-Elements and Trans-activates the Myeloid Cell-restricted gp91 phox Promoter*

B. Jacobsen, D. Skalnik, 1999, The Journal of Biological Chemistry.

Overexpression of CCAAT displacement protein represses the promiscuously active proximal gp91(phox) promoter.

W. Luo, D. Skalnik, S. Hawkins, 1999, Blood.

Differential translation of the genes encoding the proton-translocating ATPase of Escherichia coli.

D. Klionsky, D. Skalnik, R. D. Simoni, 1986, The Journal of biological chemistry.

Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer

Pearlly Yan, Kenneth P. Nephew, K. Nephew, 2005, Molecular Cancer Therapeutics.

Interferon Regulatory Factor-2 Directs Transcription from the gp91 phox Promoter*

W. Luo, D. Skalnik, 1996 .

Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity.

M. Egorin, D. Skalnik, M. Fishel, 2009, DNA repair.

Restriction ofNeuroblastoma totheProstate GlandIn Transgenic Mice

D. Dorfman, D. Skalnik, 1991 .

Methyl-CpG-Binding Proteins

D. Skalnik, 2004 .

DNA Methyltransferase protein synthesis is reduced in CXXC finger protein 1-deficient embryonic stem cells.

D. Skalnik, R. Wek, J. Sanford, 2009, DNA and cell biology.

H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes

D. Skalnik, T. Muir, K. Ge, 2020, Nucleic acids research.

CXXC Finger Protein 1 Contains Redundant Functional Domains That Support Embryonic Stem Cell Cytosine Methylation, Histone Methylation, and Differentiation

D. Skalnik, C. Tate, Jeong‐Heon Lee, 2009, Molecular and Cellular Biology.

Identification and Characterization of a Novel Human PP1 Phosphatase Complex*

D. Skalnik, J. You, Erika A. Dobrota, 2010, The Journal of Biological Chemistry.

Explorer Cfp 1 integrates both CpG content and gene activity for accurate H 3 K 4 me 3 deposition in embryonic stem cells

Robert S. Illingworth, A. Bird, R. Andrews, 2017 .

H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass

Yong Zhang, J. Wong, D. Skalnik, 2016, Stem cells.

Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.

P. Ladd, D. Skalnik, J. S. Butler, 2004, Gene.

Identification and functional characterization of the murine Rac2 gene promoter.

M. Dinauer, E. Gharehbaghi-Schnell, D. Skalnik, 1999, DNA and cell biology.

Sequence-specific binding of HMG-I(Y) to the proximal promoter of the gp91-phox gene.

E. Neufeld, D. Skalnik, 1992, Biochemical and biophysical research communications.

The membrane domain of 3-hydroxy-3-methylglutaryl-coenzyme A reductase confers endoplasmic reticulum localization and sterol-regulated degradation onto beta-galactosidase.

H. Narita, C. Kent, D. Skalnik, 1988, The Journal of biological chemistry.

Transcription | Chromatin: Methyl-CpG-Binding Proteins

D. Skalnik, Jeong‐Heon Lee, 2021, Encyclopedia of Biological Chemistry III.

Chromatin: Methyl-CpG-Binding Proteins

D. Skalnik, 2013 .

Mechanisms of 3-hydroxy-3-methylglutaryl coenzyme A reductase overaccumulation in three compactin-resistant cell lines.

E. Hardeman, R. Schimke, D. Skalnik, 1985, The Journal of biological chemistry.

CFP1 governs uterine epigenetic landscapes to intervene in progesterone responses for uterine physiology and suppression of endometriosis.

F. DeMayo, J. Lydon, D. Skalnik, 2023, Nature communications.

Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a

Jonghwan Kim, Bilal Cakir, Yangfei Xiang, 2018, Nature Communications.

Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells.

Robert S. Illingworth, A. Bird, R. Andrews, 2012, Genes & development.