S. Onesti

发表

Structure and evolutionary origins of the CMG complex

S. Onesti, S. MacNeill, 2013, Chromosoma.

Structural studies of the archaeal MCM complex in different functional states.

P. Brick, M. van Heel, T. Pape, 2006, Journal of structural biology.

The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli.

Andrew D. Miller, P. Brick, A. Miller, 1995, Structure.

Aplysia limacina myoglobin. Crystallographic analysis at 1.6 A resolution.

A Coda, M Brunori, M Bolognesi, 1989, Journal of molecular biology.

gky 723 p 15 PAF binding to PCNA modulates the DNA sliding surface

E. Crespan, G. Maga, R. Crehuet, 2018 .

Structural basis of human PCNA sliding on DNA

R. Crehuet, A. De Biasio, F. Blanco, 2017, Nature Communications.

Atomic Force Microscopy Investigation of the Interactions between the MCM Helicase and DNA

L. Casalis, S. Onesti, B. Medagli, 2021, Materials.

Reply to: “Does PCNA diffusion on DNA follow a rotation-coupled translation mechanism?”

A. De Biasio, S. Onesti, M. De March, 2020, Nature Communications.

Analysis of the Zn-Binding Domains of TRIM32, the E3 Ubiquitin Ligase Mutated in Limb Girdle Muscular Dystrophy 2H

G. Meroni, S. Onesti, C. Migliore, 2019, Cells.

Structural alignment and analysis of two distantly related proteins: Aplysia limacina myoglobin and sea lamprey globin

A. Lesk, M. Bolognesi, A. Pastore, 1988, Proteins.

DNA-conjugated gold nanoparticles based colorimetric assay to assess helicase activity: a novel route to screen potential helicase inhibitors

L. Casalis, S. Onesti, P. Parisse, 2017, Scientific Reports.

The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)

I. Luque, A. Rojas, A. De Biasio, 2019, The Journal of Biological Chemistry.

Overexpression and characterization of the 100K protein of Fowl adenovirus-4 as an antiviral target.

S. Onesti, M. Iqbal, M. D. March, 2017, Virus research.

Structure of the Kunitz-type soybean trypsin inhibitor (STI): implication for the interactions between members of the STI family and tissue-plasminogen activator.

P. Brick, D. Blow, S. Onesti, 1998, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary diffraction studies of Erythrina trypsin inhibitor.

P. Brick, D. Maeder, S. Onesti, 1989, Journal of molecular biology.

Status of the crystallography beamlines at Elettra

S. Mande, J. Plaisier, S. Onesti, 2015 .

Structural and Functional Insights into the DNA Replication Factor Cdc45 Reveal an Evolutionary Relationship to the DHH Family of Phosphoesterases*

O. Gileadi, H. Amenitsch, F. Pisani, 2011, The Journal of Biological Chemistry.

Structure and evolutionary origins of the CMG complex

S. Onesti, S. MacNeill, 2013, Chromosoma.

Mutations in Subdomain B of the Minichromosome Maintenance (MCM) Helicase Affect DNA Binding and Modulate Conformational Transitions*

A. Patwardhan, A. Leech, J. Chong, 2009, Journal of Biological Chemistry.

Active site of lysyl-tRNA synthetase: structural studies of the adenylation reaction.

P. Brick, S. Onesti, G. Desogus, 2000, Biochemistry.

Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds.

P. Brick, D. Blow, S. Onesti, 1991, Journal of molecular biology.

Crystal structure of RPB5, a universal eukaryotic RNA polymerase subunit and transcription factor interaction target.

P. Brick, R. Weinzierl, S. Onesti, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II

Finn Werner, P. Brick, F. Werner, 2005, Nucleic acids research.

Crystal structure and RNA binding of the Rpb 4 / Rpb 7 subunits of human RNA polymerase II

P. Brick, F. Werner, S. Onesti, 2005 .

Structural and functional homology between the RNAP(I) subunits A14/A43 and the archaeal RNAP subunits E/F.

P. Brick, F. Werner, S. Onesti, 2003, Nucleic acids research.

Structure of an archaeal homolog of the eukaryotic RNA polymerase II RPB4/RPB7 complex.

F Werner, P. Brick, F. Werner, 2001, Molecular cell.

Crystallization and preliminary diffraction studies of the RNA polymerase subunit RPB5 from Saccharomyces cerevisiae.

R. Weinzierl, S. Onesti, J. J. Eloranta, 1999, Acta crystallographica. Section D, Biological crystallography.

Binding of hirudin to human α, β and γ-thrombin: A comparative kinetic and thermodynamic study

M. Bolognesi, P. Ascenzi, M. Coletta, 1992 .

FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability

A. Boavida, Diana Santos, F. Pisani, 2022, bioRxiv.

Binding of the kunitz‐type trypsin inhibitor DE‐3 from Erythrina caffra seeds to serine proteinases: a comparative study

M Bolognesi, M. Bolognesi, P. Ascenzi, 1992, Journal of molecular recognition : JMR.

SOYBEAN TRYPSIN INHIBITOR

P. Brick, D. Blow, S. Onesti, 1998 .

The tumor suppressor inhibitor of growth 4 binds double‐stranded DNA through its disordered central region

F. Blanco, S. Onesti, N. Merino, 2017, FEBS letters.

Molecular and Cellular Functions of the Warsaw Breakage Syndrome DNA Helicase DDX11

F. Pisani, S. Onesti, Ettore Napolitano, 2018, Genes.

New insights into the GINS complex explain the controversy between existing structural models

I. Taylor, A. Patwardhan, M. Carroni, 2017, Scientific reports.

Identification of the first archaeal oligopeptide-binding protein from the hyperthermophile Aeropyrum pernix

M. Rossi, G. Marino, S. Onesti, 2006, Extremophiles.

Structural biology of MCM helicases

Alessandro Costa, S. Onesti, 2009, Critical reviews in biochemistry and molecular biology.

Structure and Activity of the Cdc45-Mcm2–7-GINS (CMG) Complex, the Replication Helicase

S. Onesti, M. D. March, Barbara Medagli, 2016 .

Insights into the architecture of the replicative helicase from the structure of an archaeal MCM homolog.

S. Nair, I. Cann, Alessandro Costa, 2009, Structure.

The Elongator subunit Elp3 contains a Fe4S4 cluster and binds S‐adenosylmethionine

P. Brick, C. Paraskevopoulou, S. Fairhurst, 2006, Molecular microbiology.

Two further patients with Warsaw breakage syndrome. Is a mild phenotype possible?

P. Gasparini, A. Savoia, F. Corsolini, 2019, Molecular genetics & genomic medicine.

Unstructured N Terminus of the RNA Polymerase II Subunit Rpb4 Contributes to the Interaction of Rpb4·Rpb7 Subcomplex with the Core RNA Polymerase II of Saccharomyces cerevisiae*

S. Onesti, Jiyoti Verma-Gaur, B. Balakrishnan, 2008, Journal of Biological Chemistry.

Structure and mechanism of hexameric helicases.

S. Onesti, Barbara Medagli, 2013, Advances in experimental medicine and biology.

C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W)

M. McPherson, S. Onesti, A. Shehzad, 2020, International journal of molecular sciences.

Inhibition of Human α-, β- and γ-Thrombin by mono-, bis-, tris- and tetra-Benzamidine Structures: Thermodynamic Study

M. Bolognesi, R. Fruttero, P. Ascenzi, 1992 .

The MCM complex: (just) a replicative helicase?

Alessandro Costa, S. Onesti, 2008, Biochemical Society transactions.

Binding of hirudin to human alpha, beta and gamma-thrombin. A comparative kinetic and thermodynamic study.

M. Bolognesi, M. Coletta, E. Menegatti, 1992, Journal of molecular biology.

Identification and characterization of a DNA primase from the hyperthermophilic archaeon Methanococcus jannaschii.

P. Brick, M. Rossi, F. Pisani, 1999, Nucleic acids research.

Hexameric ring structure of the full‐length archaeal MCM protein complex

M. van Heel, T. Pape, Shaoxia Chen, 2003, EMBO reports.

Cryo‐electron microscopy reveals a novel DNA‐binding site on the MCM helicase

A. Patwardhan, Z. Kelman, S. Nair, 2008, The EMBO journal.

Structural basis of the Methanothermobacter thermautotrophicus MCM helicase activity

P. Brick, M. van Heel, T. Pape, 2006, Nucleic acids research.

Amino Acids of the Sulfolobus solfataricus Mini-chromosome Maintenance-like DNA Helicase Involved in DNA Binding/Remodeling*

M. Rossi, F. Pisani, S. Onesti, 2004, Journal of Biological Chemistry.

Bioinformatic analysis of RecQ4 helicases reveals the presence of a RQC domain and a Zn knuckle.

A. Vindigni, S. Onesti, Francesca Marino, 2013, Biophysical chemistry.

Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases

E. Buratti, A. Bhardwaj, G. Musco, 2016, Scientific Reports.

A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels

V. Torre, Alex Rodriguez, A. Laio, 2015, Proceedings of the National Academy of Sciences.

The Human RecQ4 Helicase Contains a Functional RecQ C-terminal Region (RQC) That Is Essential for Activity*

S. Onesti, A. Mojumdar, Francesca Marino, 2016, The Journal of Biological Chemistry.

Crystallization and preliminary diffraction studies of Escherichia coli lysyl-tRNA synthetase (LysU).

P. Brick, A. Miller, P. Plateau, 1994, Journal of Molecular Biology.

Genomic integrity and mitochondrial metabolism defects in Warsaw syndrome cells: a comparison with Fanconi anemia

C. Mecucci, A. Savoia, N. Zini, 2021, Journal of cellular physiology.

Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.

P. Brick, P. Plateau, A. Brevet, 2000, Biochemistry.

1H, 15N and 13C chemical shift assignments for the winged helix domains of two archeal MCM C-termini

O. Ohlenschläger, S. Onesti, M. Görlach, 2013, Biomolecular NMR Assignments.

The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)

I. Luque, A. Rojas, A. De Biasio, 2019, The Journal of Biological Chemistry.

Binding of the bovine and porcine pancreatic secretory trypsin inhibitor (Kazal) to human leukocyte elastase: a thermodynamic study.

M. Bolognesi, E. Menegatti, R. Petruzzelli, 1991, Journal of enzyme inhibition.

FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability

A. Boavida, Diana Santos, F. Pisani, 2024, EMBO reports.

Structural biology of MCM helicases

Alessandro Costa, S. Onesti, 2009, Critical reviews in biochemistry and molecular biology.