Z. Lai

发表

Control of Cell Proliferation and Apoptosis by Mob as Tumor Suppressor, Mats

Ying Li, Xiaomu Wei, Nikolas Nikolaidis, 2005, Cell.

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

Li Li, Xiaomu Wei, Joungmok Kim, 2007, Genes & development.

LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.

R. Hakem, K. Guan, Cun-Yu Wang, 2013, Cell reports.

Tramtrack 69 Is Positively and Autonomously Required for Drosophila Photoreceptor Development

Y. Li, Z. Lai, 1999 .

The N-terminal BTB/POZ domain and C-terminal sequences are essential for Tramtrack69 to specify cell fate in the developing Drosophila eye.

Y. Li, Z. Lai, Y. Wen, 2000, Genetics.

Recent progress in studies of factors that elicit pancreatic β-cell expansion

Z. Lai, Qiu Li, 2014, Protein & Cell.

Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival

Z. Lai, Qiu Li, Yurika Matsui, 2016, Protein & Cell.

The yan gene is highly conserved in Drosophila and its expression suggests a complex role throughout development

Z. Lai, Mitch Price, 1999, Development Genes and Evolution.

Characterization of the structure and transcriptional patterns of the gene encoding the late histone subtype H1-beta of the sea urchin Strongylocentrotus purpuratus

Z. Lai, G. Childs, 1988, Molecular and cellular biology.

Isolation, characterization, and expression of the gene encoding the late histone subtype H1-gamma of the sea urchin Strongylocentrotus purpuratus

J. Knowles, Z. Lai, G. Childs, 1987, Molecular and cellular biology.

Isolation, Characterization, and Expression of the Gene Encoding the Late Histone Subtype Hi-Gamma of the Sea Urchin Strongylocentrotus purpuratus

J. Knowles, Z. Lai, G. Childs, 2022 .

LATS 2 Suppresses Oncogenic Wnt Signaling by Disrupting b-Catenin / BCL 9 Interaction

R. Hakem, K. Guan, Cun-Yu Wang, 2013 .

Loss of function of the Drosophila zfh-1 gene results in abnormal development of mesodermally derived tissues.

G. Rubin, M. Bate, Z. Lai, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Both basal and ontogenic promoter elements affect the timing and level of expression of a sea urchin H1 gene during early embryogenesis.

Z. Lai, R. Maxson, G. Childs, 1988, Genes & development.

An embryonic enhancer determines the temporal activation of a sea urchin late H1 gene

D. DeAngelo, Z. Lai, G. Childs, 1989, Molecular and cellular biology.

Evolutionary conservation of the leucine-rich repeat transmembrane protein Gp150 in Drosophila and Bombyx

Z. Lai, D. Nguyen, D. Dhulkotia, 2000, Development Genes and Evolution.

Evolution of the mob Gene Family

M. Nei, N. Nikolaidis, Z. Lai, 2009 .

Akt is negatively regulated by Hippo signaling for growth inhibition in Drosophila.

X. Ye, Z. Lai, Yaoting Deng, 2012, Developmental biology.

TEAD mediates YAP-dependent gene induction and growth control.

Jiandie D. Lin, A. Chinnaiyan, Siming Li, 2008, Genes & development.

Developmental control of promoter-specific factors responsible for the embryonic activation and inactivation of the sea urchin early histone H3 gene.

Z. Lai, G. Childs, H. Fei, 1989, Genes & development.

Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development

S. Girirajan, Z. Lai, Matthew Jensen, 2019, bioRxiv.

Scabrous and Gp150 are endosomal proteins that regulate Notch activity

M. Fetchko, Z. Lai, N. Baker, 2003, Development.

Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer

Z. Lai, Tian Yu, John Bachman, 2014, Protein & Cell.

Evolution of the hedgehog gene family.

S. Kumar, Z. Lai, K. A. Balczarek, 1996, Genetics.

Evolution of functional diversification of the paired box (Pax) DNA-binding domains.

S. Kumar, Z. Lai, K. A. Balczarek, 1997, Molecular biology and evolution.

Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein

Gerald M. Rubin, G. Rubin, Z. Lai, 1992, Cell.

Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila.

Xiaomu Wei, Z. Lai, Takeshi Shimizu, 2010, Developmental biology.

Mob as tumor suppressor is regulated by bantam microRNA through a feedback loop for tissue growth control.

Z. Lai, Yifan Zhang, 2013, Biochemical and biophysical research communications.

The yan gene is highly conserved in Drosophila and its expression suggests a complex role throughout development

Z. Lai, Zhi-Chun Lai, 2022 .

Evidence for a Tumor Suppressor Role for the Large Tumor Suppressor Genes LATS1 and LATS2 in Human Cancer

Z. Lai, Tian Yu, John Bachman, 2013, Genetics.

Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila

Xiaomu Wei, Z. Lai, Takeshi Shimizu, 2007, The EMBO journal.

Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche.

R. Paulson, Z. Lai, A. Patterson, 2019, Blood advances.

Dual Role of a C-Terminally Truncated Isoform of Large Tumor Suppressor Kinase 1 in the Regulation of Hippo Signaling and Tissue Growth.

R. Paulson, Z. Lai, Yifan Zhang, 2019, DNA and cell biology.

Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein.

K. Guan, X. Ye, Z. Lai, 2009, Cancer research.

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation.

Kun-Liang Guan, Hyun Woo Park, Susan S. Taylor, 2013, Genes & development.

Hippo activation through homodimerization and membrane association for growth inhibition and organ size control.

Z. Lai, Yifan Zhang, Yurika Matsui, 2013, Developmental biology.

The mob as tumor suppressor Gene Is Essential for Early Development and Regulates Tissue Growth in Drosophila

Z. Lai, Takeshi Shimizu, L. Ho, 2008, Genetics.

Yap1 promotes proliferation of transiently amplifying stress erythroid progenitors during erythroid regeneration.

R. Paulson, Z. Lai, Siyang Hao, 2019, Experimental hematology.

Shortsighted acts in the decapentaplegic pathway in Drosophila eye development and has homology to a mouse TGF-beta-responsive gene.

G. Rubin, J. Treisman, Z. Lai, 1995, Development.

Photoreceptor Cell Differentiation Requires Regulated Proteolysis of the Transcriptional Repressor Tramtrack

Y. Li, R. Carthew, Z. Lai, 1997, Cell.

The Drosophila homolog of Onecut homeodomain proteins is a neural-specific transcriptional activator with a potential role in regulating neural differentiation

Z. Lai, M. Rohrbaugh, D. Nguyen, 2000, Mechanisms of Development.

Tramtrack69 is positively and autonomously required for Drosophila photoreceptor development.

Y. Li, Z. Lai, Z C Lai, 1999, Genetics.

Two distantly positioned PDZ domains mediate multivalent INAD–phospholipase C interactions essential for G protein‐coupled signaling

W. Stark, Y. Li, Z. Lai, 1998, The EMBO journal.

Mutual regulation between Hippo signaling and actin cytoskeleton

Z. Lai, Yurika Matsui, 2013, Protein & Cell.

The mob as tumor suppressor (mats1) gene is required for growth control in developing zebrafish embryos.

Yuan Yuan, Shuo Lin, Zuoyan Zhu, 2009, International Journal of Developmental Biology.

Mutual regulation between Hippo signaling and actin cytoskeleton

Z. Lai, Yurika Matsui, 2013, Protein & Cell.

Drosophila Gp150 is required for early ommatidial development through modulation of Notch signaling

Ying Li, Wei Huang, Michael Fetchko, 2002, The EMBO journal.

Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer

Z. Lai, Tian Yu, John Bachman, 2014, Protein & Cell.

Editor's Note: Both TEAD-Binding and WW Domains Are Required for the Growth Stimulation and Oncogenic Transformation Activity of Yes-Associated Protein

K. Guan, Z. Lai, Joungmok Kim, 2021, Cancer Research.

The Drosophila ortholog of breast cancer metastasis suppressor gene, dBrms1, is critical for developmental timing through regulating ecdysone signaling.

Yuan Yuan, Zuoyan Zhu, Z. Lai, 2013, Developmental biology.

Efficient multiplexed genome engineering with a polycistronic tRNA and CRISPR guide-RNA reveals an important role of detonator in reproduction of Drosophila melanogaster

Huiqing Zeng, Aimin Liu, Z. Lai, 2021, PloS one.

Recent progress in studies of factors that elicit pancreatic β-cell expansion

Z. Lai, Qiu Li, 2014, Protein & Cell.

Repression of Drosophila photoreceptor cell fate through cooperative action of two transcriptional repressors Yan and Tramtrack.

Y. Li, M. Fetchko, Z. Lai, 1997, Genetics.

Loss of tramtrack gene activity results in ectopic R7 cell formation, even in a sina mutant background.

G. Rubin, Y. Li, F. Karim, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival

Z. Lai, Qiu Li, Yurika Matsui, 2016, Protein & Cell.

Notch Activation of yan Expression Is Antagonized by RTK/Pointed Signaling in the Drosophila Eye

E. Ramos, Z. Lai, M. Rohrbaugh, 2002, Current Biology.

The defender against apoptotic cell death 1 gene is required for tissue growth and efficient N-glycosylation in Drosophila melanogaster.

Z. Lai, Yifan Zhang, Chang Cui, 2016, Developmental biology.

TEAD mediates YAP-dependent gene induction and growth control.

Jiandie D. Lin, A. Chinnaiyan, Siming Li, 2008, Genes & development.

Bimolecular Fluorescence Complementation (BiFC) in Tissue Culture and in Developing Tissues of Drosophila to Study Protein-Protein Interactions.

Z. Lai, Yurika Matsui, 2019, Methods in molecular biology.

Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila.

Xiaomu Wei, Z. Lai, Takeshi Shimizu, 2010, Developmental biology.