J. Pike

Sungtae Kim, S. Christakos, Yan Liu, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 Potently Stimulates Gene-specific DNA Binding of the Vitamin D Receptor in Osteoblasts*

H. DeLuca, J. Pike, Hironori Yamamoto, 2003, Journal of Biological Chemistry.

Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.

J. Schrooten, T. Dresselaers, L. Bonewald, 2012, The Journal of clinical investigation.

Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression.

J. Pike, K. Dienger, A. C. Bendixen, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Genome-wide analysis of the VDR/RXR cistrome in osteoblast cells provides new mechanistic insight into the actions of the vitamin D hormone

J. Pike, M. Meyer, Paul D. Goetsch, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

Androgens suppress osteoclast formation induced by RANKL and macrophage-colony stimulating factor.

S. Srivastava, J. Pike, P. Pathrose, 2001, Endocrinology.

Targeted genomic deletions identify diverse enhancer functions and generate a kidney-specific, endocrine-deficient Cyp27b1 pseudo-null mouse

R. Redfield, Glenville Jones, J. Pike, 2019, The Journal of Biological Chemistry.

A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene Cyp27b1 essential for vitamin D3 activation

Glenville Jones, J. Pike, M. Meyer, 2017, The Journal of Biological Chemistry.

Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells*

J. Rubin, B. Sen, J. Pike, 2016, The Journal of Biological Chemistry.

Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D.

R. Wilkinson, J. Pike, J. Adams, 2010, The Journal of clinical endocrinology and metabolism.

Molecular Actions of 1,25‐Dihydroxyvitamin D3 on Genes Involved in Calcium Homeostasis

Sungtae Kim, J. Pike, M. Meyer, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The regulation of FGF23 production in bone and outside of bone

J. Pike, Erica L Clinkenbeard, S. Lee, 2021 .

Immunocytochemical detection of 1,25-dihydroxyvitamin D receptors in normal human tissues

M. Haussler, R. Coombes, J. Pike, 1988 .

Targeted deletion of a distant transcriptional enhancer of the receptor activator of nuclear factor-kappaB ligand gene reduces bone remodeling and increases bone mass.

R. Weinstein, C. O’Brien, S. Manolagas, 2008, Endocrinology.

Importin 4 Is Responsible for Ligand-independent Nuclear Translocation of Vitamin D Receptor*

K. Ozono, Y. Yoneda, J. Pike, 2005, Journal of Biological Chemistry.

Receptors for 1,25-dihydroxyvitamin D3 in chick pancreas: a partial physical and functional characterization.

J. Pike, J. Pike, 1982, Journal of steroid biochemistry.

The ovary: a target organ for 1,25-dihydroxyvitamin D3.

M. Haussler, S. Marion, J. Pike, 1983, Endocrinology.

Vitamin D-binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo.

B. Hollis, J. Pike, Lee A. Zella, 2008, Endocrinology.

An ochre mutation in the vitamin D receptor gene causes hereditary 1,25-dihydroxyvitamin D3-resistant rickets in three families.

B. O’Malley, Z. Hochberg, J. Pike, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Vitamin D3--resistant fibroblasts have immunoassayable 1,25-dihydroxyvitamin D3 receptors.

M. Haussler, U. Liberman, J. Pike, 1984, Science.

Sensitive and specific detection of retinoid receptor subtype proteins in cultured cell and tumor extracts.

M. Gottardis, J. Pike, E. Allegretto, 1994, Molecular endocrinology.

Effect of growth hormone on vitamin D metabolism

M. Haussler, J. Pike, I. Macintyre, 1978, Nature.

Evidence for a role of prolactin in calcium homeostasis: regulation of intestinal transient receptor potential vanilloid type 6, intestinal calcium absorption, and the 25-hydroxyvitamin D(3) 1alpha hydroxylase gene by prolactin.

P. Dhawan, S. Christakos, J. Pike, 2010, Endocrinology.

Dynamic changes in circulating 1,25-dihydroxyvitamin D during reproduction in rats.

M. Haussler, J. Parker, J. Pike, 1979, Science.

Calcium metabolism during lactation: enhanced intestinal calcium absorption in vitamin D-deprived, hypocalcemic rats.

M. Haussler, J. Pike, S. U. Toverud, 1981, Endocrinology.

Intracellular receptors mediate the biologic action of 1,25-dihydroxyvitamin D3.

J. Pike, 2009, Nutrition reviews.

1,25-Dihydroxyvitamin D3 does not up-regulate vitamin D receptor messenger ribonucleic acid levels in hypophosphatemic mice.

M. Haussler, J. Pike, Y. Seino, 1992, Bone and mineral.

Retinoid X Receptor Acts as a Hormone Receptor in Vivo to Induce a Key Metabolic Enzyme for 1,25-Dihydroxyvitamin D3(*)

B. Hollis, J. Pike, M. Boehm, 1995, The Journal of Biological Chemistry.

Multiple enhancer regions located at significant distances upstream of the transcriptional start site mediate RANKL gene expression in response to 1,25-dihydroxyvitamin D3

Sungtae Kim, J. Pike, M. Meyer, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

A control region near the fibroblast growth factor 23 gene mediates response to phosphate, 1,25(OH)2D3 and LPS in vivo.

J. Pike, M. Meyer, M. Onal, 2019, Endocrinology.

An improved radioreceptor assay for 1,25-dihydroxyvitamin D in human plasma.

M. Haussler, J. Pike, J. Mancini, 1981, Analytical biochemistry.

A potent analog of 1α,25-dihydroxyvitamin D3 selectively induces bone formation

H. DeLuca, J. Pike, Hironori Yamamoto, 2002, Proceedings of the National Academy of Sciences of the United States of America.

1,25-Dihydroxyvitamin D3 inhibits the clonogenic growth of transformed cells via its receptor.

M. Haussler, S. Marion, J. Pike, 1986, Biochemical and biophysical research communications.

1,25-Dihydroxyvitamin D3 and the aging-related Forkhead Box O and Sestrin proteins in osteoblasts

R. Bouillon, G. Eelen, R. Gijsbers, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Bone vitamin D-dependent calcium-binding protein is localized in chondrocytes of growth-plate cartilage

M. Haussler, T. Clemens, D. Dempster, 1986, Calcified Tissue International.

The unsettled science of nonrenal calcitriol production and its clinical relevance.

J. Pike, M. Meyer, 2020, The Journal of clinical investigation.

Hormonal effects of vitamin D3 on epidermal melanocytes

V. Swope, Z. Abdel‐Malek, J. Nordlund, 1988, Journal of cellular physiology.

The Molecular Basis of Hereditary 1 , 25Dihydroxyvitamin 25Dihydroxyvitamin 25Dihydroxyvitamin D 3 Resistant Rickets in Seven Related Families

Z. Hochberg, J. Pike, P. Malloy, 2013 .

The molecular basis of hereditary 1,25-dihydroxyvitamin D3 resistant rickets in seven related families.

Z. Hochberg, J. Pike, P. Malloy, 1990, The Journal of clinical investigation.

Biosynthesis, purification and receptor binding properties of high specific radioactivity 1 alpha, 24(R),25-trihydroxy-[26,27-methyl-3H]-vitamin D3.

M. Haussler, J. Pike, J. Chandler, 1982, Journal of steroid biochemistry.

C-terminal proteolysis of the avian 1,25-dihydroxyvitamin D3 receptor.

M. Haussler, J. Pike, E. Allegretto, 1987, Biochemical and biophysical research communications.

Immunochemical detection of unique proteolytic fragments of the chick 1,25-dihydroxyvitamin D3 receptor. Distinct 20-kDa DNA-binding and 45-kDa hormone-binding species.

M. Haussler, J. Pike, E. Allegretto, 1987, The Journal of biological chemistry.

Trypsin cleavage of chick 1,25-dihydroxyvitamin D3 receptors. Generation of discrete polypeptides which retain hormone but are unreactive to DNA and monoclonal antibody.

J. Pike, E. Allegretto, 1985, The Journal of biological chemistry.

[62] Characteristics and purification of the intestinal receptor for 1,25-dihydroxyvitamin D

M. Haussler, J. Pike, 1980 .

Phenotypic and functional analysis of 1,25-dihydroxyvitamin D3 receptor mediated modulation of the human myeloma cell line RPMI 8226.

R. Bataille, M. Haussler, S. Marion, 1988, Cancer research.

Emerging concepts on the biologic role and mechanism of action of 1,25-dihydroxyvitamin D3

J. Pike, 1987, Steroids.

Biochemical evidence for 1,25-dihydroxyvitamin D receptor macromolecules in parathyroid, pancreatic, pituitary, and placental tissues.

M. Haussler, J. Pike, L. Goozé, 1980, Life sciences.

1,25-Dihydroxyvitamin D3 receptors in rat kidney cytosol.

M. Haussler, J. Pike, J. Chandler, 1979, Biochemical and biophysical research communications.

Immunocytology with microwave-fixed fibroblasts shows 1 alpha,25- dihydroxyvitamin D3-dependent rapid and estrogen-dependent slow reorganization of vitamin D receptors

H. DeLuca, J. Pike, S. Marx, 1990, The Journal of cell biology.

Immunocytochemical localization of the 1,25-dihydroxyvitamin D3 receptor in target cells.

M. Haussler, T. Clemens, D. Dempster, 1988, Endocrinology.

Immunocytochemical detection of 1,25-dihydroxyvitamin D receptors in normal human tissues.

M. Haussler, R. Coombes, J. Pike, 1987, The Journal of clinical endocrinology and metabolism.

Development of hybridomas secreting monoclonal antibodies to the chicken intestinal 1 alpha,25-dihydroxyvitamin D3 receptor.

M. Haussler, S. Marion, J. Pike, 1982, Proceedings of the National Academy of Sciences of the United States of America.

A potent analog of 1alpha,25-dihydroxyvitamin D3 selectively induces bone formation.

H. DeLuca, J. Pike, Hironori Yamamoto, 2002, Proceedings of the National Academy of Sciences of the United States of America.

A unique mutation in the vitamin D receptor gene in three Japanese patients with vitamin D-dependent rickets type II: utility of single-strand conformation polymorphism analysis for heterozygous carrier detection.

I. Yokota, T. Saijo, E. Naito, 1991, American journal of human genetics.

Expression of the vitamin D receptor in skeletal muscle: are we there yet?

J. Pike, 2014, Endocrinology.

Role of prolactin in vitamin D metabolism and calcium absorption during lactation in the rat.

M. Haussler, J. Pike, I. Macintyre, 1982, The Journal of endocrinology.

Influence of estrogen on renal vitamin D hydroxylases and serum 1alpha,25-(OH)2D3 in chicks.

M. Haussler, J. Pike, I. Macintyre, 1978, The American journal of physiology.

The RUNX2 Cistrome in Osteoblasts

J. Pike, M. Meyer, N. Benkusky, 2014, The Journal of Biological Chemistry.

The RUNX2 Cistrome in Osteoblasts: Characterization, Downregulation Following Differentiation and Relationship to Gene Expression*

J. Pike, M. Meyer, N. Benkusky, 2014 .

Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes

J. Pike, M. Meyer, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Ultrastructural immunocytochemical localization of endogenous 1,25-dihydroxyvitamin D3 and its receptors in osteoblasts and osteocytes from neonatal mouse and rat calvaria.

M. Haussler, R. Bouillon, G. Morel, 1987, Bone and mineral.

Mechanistic homeostasis of vitamin D metabolism in the kidney through reciprocal modulation of Cyp27b1 and Cyp24a1 expression

J. Pike, M. Meyer, 2020, The Journal of Steroid Biochemistry and Molecular Biology.

Rapid genomic changes by mineralotropic hormones and kinase SIK inhibition drive coordinated renal Cyp27b1 and Cyp24a1 expression via CREB modules

Marc N. Wein, J. Pike, M. Meyer, 2022, The Journal of biological chemistry.

Dexamethasone and interleukin-1 potently synergize to stimulate the production of granulocyte colony-stimulating factor in differentiated THP-1 cells.

K. Lei, J. Pike, Y. Wang, 1997, Biochemical and biophysical research communications.

Nuclear receptor comodulators do matter

J. Pike, N. Shevde, 2002 .

New nonsteroidal vitamin D receptor modulators: Are these ligands the real deal?

J. Pike, 2006 .

1,25-Dihydroxyvitamin D 3 -induced Differentiation in a Human Promyelocytic Leukemia Cell Line (HL-60) : Receptor-mediated Maturation to Macrophage-like Cells

M. Haussler, D. Mangelsdorf, H. Koeffler, 2002 .

A new point mutation in the deoxyribonucleic acid-binding domain of the vitamin D receptor in a kindred with hereditary 1,25-dihydroxyvitamin D-resistant rickets.

K. Ozono, J. Pike, K. Nagashima, 1993, The Journal of clinical endocrinology and metabolism.

Mouse and human BAC transgenes recapitulate tissue-specific expression of the vitamin D receptor in mice and rescue the VDR-null phenotype.

J. Goellner, C. O’Brien, J. Pike, 2014, Endocrinology.

1,25-Dihydroxyvitamin D3 receptors: altered functional domains are associated with cellular resistance to vitamin D3.

M. Haussler, D. Mangelsdorf, S. Marion, 1986, Advances in experimental medicine and biology.

The Inhibitory Effect of Interleukin‐10 on Mouse Osteoclast Formation Involves Novel Tyrosine‐Phosphorylated Proteins

J. Pike, M. Hong, C. H. Jin, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A Novel Distal Enhancer Mediates Inflammation‐, PTH‐, and Early Onset Murine Kidney Disease‐Induced Expression of the Mouse Fgf23 Gene

J. Pike, M. Meyer, M. Onal, 2017, JBMR plus.

Emerging regulatory paradigms for control of gene expression by 1,25-dihydroxyvitamin D3

R. D. Nerenz, J. Pike, M. Meyer, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

E. Takeda, K. Miyamoto, Y. Taketani, 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells

M. Haussler, D. Mangelsdorf, H. Koeffler, 1984, The Journal of cell biology.

Circulating levels and function of 1,25-(OH)2D3 in lactation.

M. Haussler, J. Pike, S. U. Toverud, 1983, Journal of steroid biochemistry.

Regulation of 1,25-dihydroxyvitamin D3 receptor gene expression by 1,25-dihydroxyvitamin D3 in the parathyroid in vivo.

E. Keshet, J. Silver, J. Pike, 1990, The Journal of clinical investigation.

Closing in on Vitamin D Action in Skeletal Muscle: Early Activity in Muscle Stem Cells?

J. Pike, 2016, Endocrinology.

A High-Calcium and Phosphate Rescue Diet and VDR-Expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and Renal Cyp27b1 and Cyp24a1 Expression in VDR Null Mice.

Glenville Jones, J. Pike, S. Lee, 2015, Endocrinology.

The vitamin D receptor: a primitive steroid receptor related to thyroid hormone receptor.

B. O’Malley, J. Pike, D. McDonnell, 1988, Journal of steroid biochemistry.

MOLECULAR ACTION OF 1,25‐DIHYDROXYVITAMIN D3: NEW CULTURED CELL MODELS *

M. Haussler, S. Manolagas, L. Deftos, 1981, Annals of the New York Academy of Sciences.

Intestinal 1,25-dihydroxyvitamin D3 receptors: hormone-dependent uptake and saturability of nuclear components in vitro.

J. Pike, 1981, Life sciences.

Survey of vitamin D metabolite-binding components in rachitic chick tissues: Detection with high specific activity sterols

M. Haussler, J. Pike, J. Chandler, 1979 .

Alternative promoters and renal cell-specific regulation of the mouse type IIa sodium-dependent phosphate cotransporter gene.

S. Kato, E. Takeda, K. Miyamoto, 2005, Biochimica et biophysica acta.

Analysis of SOST expression using large minigenes reveals the MEF2C binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D3 or TGFβ1 responsiveness

J. Pike, S. Hansen, H. C. S. John, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

Development of a radioligand immunoassay for 1,25-dihydroxycholecalciferol receptors utilizing monoclonal antibody.

M. Haussler, J. Pike, S. Dokoh, 1984, The Biochemical journal.

Purification of chicken intestinal receptor for 1,25-dihydroxyvitamin D.

M. Haussler, J. Pike, 1979, Proceedings of the National Academy of Sciences of the United States of America.

The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.

K. Ozono, J. Pike, R. Scott, 1990, The Journal of biological chemistry.

1,25-Dihydroxyvitamin D3 induces 25-hydroxyvitamin D3-24-hydroxylase in a cultured monkey kidney cell line (LLC-MK2) apparently deficient in the high affinity receptor for the hormone.

M. Haussler, J. Pike, J. Chandler, 1984, The Journal of biological chemistry.

Physiological importance of vitamin D metabolism.

M. Haussler, M. Pitt, J. Pike, 1980, Progress in biochemical pharmacology.

Positive regulation of the vitamin D receptor by its cognate ligand in heterologous expression systems.

J. Pike, D. McDonnell, G. Hilliard, 1993, Molecular endocrinology.

Circulating 1alpha,25-dihydroxyvitamin D in the chicken: enhancement by injection of prolactin and during egg laying.

M. Haussler, J. Pike, I. Macintyre, 1976, Life sciences.

Elevated serum levels of 1α, 25-dihydroxycholecalciferol in lactating rats

M. Haussler, J. Pike, S. U. Toverud, 1977, Nature.

Elevated serum levels of 1alpha, 25-dihydroxycholecalciferol in lactating rats.

M. Haussler, J. Pike, S. U. Toverud, 1977, Nature.

Dexamethasone potently enhances phorbol ester-induced IL-1beta gene expression and nuclear factor NF-kappaB activation.

K. Lei, W. Dai, J. Pike, 1997, Journal of immunology.

Evidence for a reactive sulfhydryl in the DNA binding domain of the 1,25-dihydroxyvitamin D3 receptor.

J. Pike, J.Wesley Pike, 1981, Biochemical and biophysical research communications.

[63] A sensitive radioreceptor assay for 1α,25-dihydroxyvitamin D in biological fluid

M. Haussler, J. Pike, J. Chandler, 1980 .

Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3.

K. Ozono, J. Pike, D. McDonnell, 1990, Proceedings of the National Academy of Sciences of the United States of America.

CHAPTER 87 – 2-Carbon-Modified Analogs of 19-Nor-1α,25-Dihydroxyvitamin D3

H. DeLuca, J. Pike, M. Clagett-Dame, 2005 .

Reconstitution oftheVitamin D-Responsive Osteocalcin Transcription UnitinSaccharomyces cerevisiae

B. O’Malley, T. Butt, J. Pike, 1989 .

Biology and Mechanisms of Action of the Vitamin D Hormone.

S. Christakos, J. Pike, J. Pike, 2017, Endocrinology and metabolism clinics of North America.

Unique Distal Enhancers Linked to the Mouse Tnfsf11 Gene Direct Tissue-Specific and Inflammation-Induced Expression of RANKL.

J. Pike, M. Onal, A. L. Danielson, 2016, Endocrinology.

Mutant vitamin D receptors which confer hereditary resistance to 1,25-dihydroxyvitamin D3 in humans are transcriptionally inactive in vitro.

B. O’Malley, J. Pike, P. Malloy, 1989, The Journal of biological chemistry.

1,25-dihydroxyvitamin D3 receptors in rat lung during the perinatal period: regulation and immunohistochemical localization.

J. Pike, T. M. Nguyen, M. Dufour, 1990, Endocrinology.

[64] Use of chick kidney to enzymatically generate radiolabeled 1,25-dihydroxyvitamin D and other vitamin D metabolites

M. Haussler, J. Pike, J. Chandler, 1980 .

Monoclonal antibodies to chick intestinal receptors for 1,25-dihydroxyvitamin D3. Interaction and effects of binding on receptor function.

J. Pike, 1984, The Journal of biological chemistry.

Distribution and subcellular immunolocalization of 1,25-dihydroxyvitamin D3 receptors in rat epiphyseal cartilage.

M. Hauchecorne, J. Pike, H. Mathieu, 1993, Cellular and molecular biology.

Activation of Receptor Activator of NF-κB Ligand Gene Expression by 1,25-Dihydroxyvitamin D3 Is Mediated through Multiple Long-Range Enhancers

Sungtae Kim, J. Pike, Lee A. Zella, 2006, Molecular and Cellular Biology.

An enhancer 20 kilobases upstream of the human receptor activator of nuclear factor-kappaB ligand gene mediates dominant activation by 1,25-dihydroxyvitamin D3.

R. D. Nerenz, J. Pike, Melissa L. Martowicz, 2008, Molecular endocrinology.

Potent vitamin D3 analogs: their abilities to enhance transactivation and to bind to the vitamin D3 response element.

H. Koeffler, J. Pike, Y. Imai, 1995, Leukemia research.

Receptor-Mediated Action of the Vitamin D Hormone

M. Haussler, D. Mangelsdorf, S. Marion, 1987 .

High performance liquid chromatography of the 1,25-dihydroxyvitamin D3 receptor: its application toward resolution of receptor-monoclonal antibody complexes.

M. Haussler, J. Pike, M. Kelly, 1982, Biochemical and biophysical research communications.

Hormone-dependent phosphorylation of the 1,25-dihydroxyvitamin D3 receptor in mouse fibroblasts.

J. Pike, N. M. Sleator, 1985, Biochemical and biophysical research communications.

Molecular cloning of complementary DNA encoding the avian receptor for vitamin D.

M. Haussler, B. O’Malley, D. Mangelsdorf, 1987, Science.

Chicken intestinal receptor for 1,25-dihydroxyvitamin D3. Immunologic characterization and homogeneous isolation of a 60,000-dalton protein.

M. Haussler, J. Pike, N. M. Sleator, 1987, The Journal of biological chemistry.

Avian and mammalian receptors for 1,25-dihydroxyvitamin D3: in vitro translation to characterize size and hormone-dependent regulation.

M. Haussler, D. Mangelsdorf, J. Pike, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Association of 1,25-dihydroxyvitamin D3 with cultured 3T6 mouse fibroblasts. Cellular uptake and receptor-mediated migration to the nucleus.

M. Haussler, J. Pike, 1983, The Journal of biological chemistry.

A variant form of the 1,25-dihydroxyvitamin D3 receptor with low apparent hormone affinity in cultured monkey kidney cells (LLC-MK2). A model for tissue resistance to vitamin D.

M. Haussler, S. Marion, J. Pike, 1985, The Journal of biological chemistry.

CARM1 Methylates Chromatin Remodeling Factor BAF155 to Enhance Tumor Progression and Metastasis.

P. Ahlquist, W. Cai, Menggang Yu, 2016, Cancer cell.

Inhibition of vitamin D receptor-retinoid X receptor-vitamin D response element complex formation by nuclear extracts of vitamin D-resistant New World primate cells.

J. Adams, J. Pike, J. Arbelle, 1996, Endocrinology.

Effect of hormones and development on the expression of the rat 1,25-dihydroxyvitamin D3 receptor gene. Comparison with calbindin gene expression.

D. Bruns, S. Christakos, J. Pike, 1989, The Journal of biological chemistry.

1,25‐Dihydroxyvitamin D3 Stimulates Cyclic Vitamin D Receptor/Retinoid X Receptor DNA‐Binding, Co‐activator Recruitment, and Histone Acetylation in Intact Osteoblasts

Sungtae Kim, J. Pike, N. Shevde, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cell- and stage-specific expression of vitamin D receptor and calbindin genes in rat incisor: regulation by 1,25-dihydroxyvitamin D3.

A. Berdal, J. Pike, H. Mathieu, 1993, Developmental biology.

Regulation of gene expression by 1,25-dihydroxyvitamin D3 in bone cells: exploiting new approaches and defining new mechanisms.

J. Pike, M. Meyer, S. Lee, 2014, BoneKEy reports.

A unique point mutation in the human vitamin D receptor chromosomal gene confers hereditary resistance to 1,25-dihydroxyvitamin D3.

U. Liberman, J. Pike, S. Marx, 1990, Molecular endocrinology.

Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets.

B. O’Malley, R. Kesterson, D. Kieback, 1988, Science.

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

J. Shine, M. Haussler, B. O’Malley, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Overexpression of the human vitamin D3 receptor in mammalian cells using recombinant adenovirus vectors.

G. Hager, J. Pike, S. Marx, 1991, Molecular endocrinology.

Vitamin D3 receptors: structure and function in transcription.

J. Pike, J. W. Pike, J. Pike, 1991, Annual review of nutrition.

A novel distal enhancer mediates cytokine induction of mouse RANKl gene expression.

J. Pike, M. Meyer, Kathleen A. Bishop, 2009, Molecular endocrinology.

The Phosphorylated Estrogen Receptor α (ER) Cistrome Identifies a Subset of Active Enhancers Enriched for Direct ER-DNA Binding and the Transcription Factor GRHL2

Christopher L. Warren, E. Alarid, J. Pike, 2018, Molecular and Cellular Biology.

Genomic Determinants of Gene Regulation by 1,25-Dihydroxyvitamin D3 during Osteoblast-lineage Cell Differentiation*♦

J. Pike, M. Meyer, Chang-Hun Lee, 2014, The Journal of Biological Chemistry.

The vitamin D receptor: new paradigms for the regulation of gene expression by 1,25-dihydroxyvitamin D3.

J. Pike, M. Meyer, J. Pike, 2012, Rheumatic diseases clinics of North America.

Regulation of target gene expression by the vitamin D receptor - an update on mechanisms

J. Pike, M. Meyer, Kathleen A. Bishop, 2012, Reviews in Endocrine and Metabolic Disorders.

The vitamin D receptor: new paradigms for the regulation of gene expression by 1,25-dihydroxyvitamin D(3).

J. Pike, M. Meyer, J. Pike, 2010, Endocrinology and metabolism clinics of North America.

A Downstream Intergenic Cluster of Regulatory Enhancers Contributes to the Induction of CYP24A1 Expression by 1α,25-Dihydroxyvitamin D3*

J. Pike, M. Meyer, Paul D. Goetsch, 2010, The Journal of Biological Chemistry.

New techniques in transcription research extend our understanding of the molecular actions of the vitamin D hormone

J. Pike, M. Meyer, Melissa L. Martowicz, 2009 .

The Vitamin D Receptor

J. Pike, M. Meyer, S. Lee, 2005 .

Human vitamin D receptor mutations: identification of molecular defects in hypocalcemic vitamin D resistant rickets.

B. O’Malley, D. Kieback, J. Pike, 1989, Advances in experimental medicine and biology.

Vitamin D and its analogs

Glenville Jones, J. Pike, J. W. Pike, 2020 .

Mesenchymal Differentiation, Epigenetic Dynamics, and Interactions With VDR

J. Pike, M. Meyer, N. Benkusky, 2018 .

Vitamin D receptor-mediated gene regulation mechanisms and current concepts of vitamin D analog selectivity.

J. Pike, Hironori Yamamoto, N. Shevde, 2002, Advances in renal replacement therapy.

Selective Distal Enhancer Control of the Mmp13 Gene Identified through Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Genomic Deletions*

J. Pike, M. Meyer, N. Benkusky, 2015, The Journal of Biological Chemistry.

Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene

K. Umesono, R. Evans, D. Mangelsdorf, 1990, Cell.

Genome-Wide Perspectives on Vitamin D Receptor–Mediated Control of Gene Expression in Target Cells

J. Pike, M. Meyer, M. Onal, 2018 .

The vitamin D receptor: contemporary genomic approaches reveal new basic and translational insights.

Seong-Min Lee, J. Pike, M. Meyer, 2017, The Journal of clinical investigation.

Epigenetic histone modifications and master regulators as determinants of context dependent nuclear receptor activity in bone cells.

J. Pike, M. Meyer, N. Benkusky, 2015, Bone.

Distinct molecular mechanism for initiating TRAF6 signalling

Hao Wu, Yongwon Choi, Sujay K. Singh, 2002, Nature.

CHAPTER 69 - Vitamin D 3 : Synthesis, Actions, and Mechanisms in the Intestine and Colon

J. Pike, Makoto Watanuki, N. Shevde, 2006 .

Genomic Determinants of Vitamin D-Regulated Gene Expression.

J. Pike, M. Meyer, M. Onal, 2016, Vitamins and hormones.

The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone.

Ning Leng, C. Kendziorski, L. Bonewald, 2014, Molecular endocrinology.

Mechanisms of Enhancer-mediated Hormonal Control of Vitamin D Receptor Gene Expression in Target Cells*

C. O’Brien, J. Pike, M. Meyer, 2015, The Journal of Biological Chemistry.

Transcriptional activation and dimerization functions in the human vitamin D receptor.

J. Pike, S. Kerner, M. Hong, 1996, Molecular endocrinology.

Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1

J. Pike, G. Rodriguez, C. Hamilton, 2016, Oncotarget.

Progestins inhibit calcitriol-induced CYP24A1 and synergistically inhibit ovarian cancer cell viability: An opportunity for chemoprevention.

T. Conrads, J. Pike, K. Darcy, 2016, Gynecologic oncology.

Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression.

B. O’Malley, J. Pike, R. Scott, 1989, Molecular endocrinology.

Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation.

L. Donahue, T. Clemens, J. Fagin, 2000, Endocrinology.

Isolation and characterization of unsaturated fatty acids as natural ligands for the retinoid-X receptor.

H. DeLuca, A. Dobrzyń, J. Pike, 2003, Archives of biochemistry and biophysics.

Deletion of Mediator 1 suppresses TGFβ signaling leading to changes in epidermal lineages and regeneration

A. Hata, J. Pike, Thai D. Nguyen, 2020, PloS one.

High pressure liquid chromatographic detection of intracellular retinoid binding proteins from cultured cell and tumor cytosols.

M. Haussler, J. Pike, E. Allegretto, 1983, Biochemical and biophysical research communications.

Immunoselection of cDNAs to avian intestinal calcium binding protein 28K and a novel calmodulin-like protein: assessment of mRNA regulation by the vitamin D hormone.

B. Komm, M. Haussler, D. Mangelsdorf, 1987, Biochemistry.

Vitamin D metabolites in adolescents and young adults with cystic fibrosis: effects of sun and season.

M. Haussler, J. Pike, L. Taussig, 1985, The Journal of pediatrics.

Highly crosslinked vs conventional polyethylene particles--an in vitro comparison of biologic activities.

M. Laurent, J. Pike, C. Blanchard, 2008, The Journal of arthroplasty.

Genome-wide principles of gene regulation by the vitamin D receptor and its activating ligand

J. Pike, J. Pike, 2011, Molecular and Cellular Endocrinology.

Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide.

H. DeLuca, M. Benning, J. Vanhooke, 2004, Biochemistry.

Deletion of a Distal RANKL Gene Enhancer Delays Progression of Atherosclerotic Plaque Calcification in Hypercholesterolemic Mice

J. Pike, M. Onal, Sohel Shamsuzzaman, 2017, Journal of cellular biochemistry.

Human invariant natural killer T cells acquire transient innate responsiveness via histone H4 acetylation induced by weak TCR stimulation

J. Pike, J. Gumperz, Xiaohuan Wang, 2012, The Journal of experimental medicine.

Structural organization of the human vitamin D receptor chromosomal gene and its promoter.

H. Yamamoto, R. Kesterson, E. Nishiwaki, 1997, Molecular endocrinology.

Vitamin D receptor as a candidate tumor-suppressor gene in severe hyperparathyroidism of uremia.

N. Palanisamy, R. Chaganti, M. Brandi, 2000, The Journal of clinical endocrinology and metabolism.

Expression of human vitamin D receptor in Saccharomyces cerevisiae. Purification, properties, and generation of polyclonal antibodies.

B. O’Malley, J. Pike, D. McDonnell, 1990, The Journal of biological chemistry.

Receptor activator of nuclear factor-kappaB ligand-induced nuclear factor of activated T cells (C1) autoregulates its own expression in osteoclasts and mediates the up-regulation of tartrate-resistant acid phosphatase.

Sujay K. Singh, J. Pike, B. Darnay, 2008, Molecular endocrinology.

Transcriptional Regulation of the Human TNFSF11 Gene in T Cells via a Cell Type‐Selective Set of Distal Enhancers

J. Pike, J. Gumperz, M. Meyer, 2015, Journal of cellular biochemistry.

Mouse Rankl Expression Is Regulated in T Cells by c-Fos through a Cluster of Distal Regulatory Enhancers Designated the T Cell Control Region*

R. D. Nerenz, J. Pike, M. Meyer, 2011, The Journal of Biological Chemistry.

Identification of a novel mutation in hereditary vitamin D resistant rickets causing exon skipping

J. Pike, M. Hewison, S. Vadher, 1996, Clinical endocrinology.

Selective regulation of Mmp13 by 1,25(OH)2D3, PTH, and Osterix through distal enhancers

J. Pike, M. Meyer, M. Onal, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

In vitro binding of vitamin D receptor occupied by 24R, 25-dihydroxyvitamin D3 to vitamin D responsive element of human osteocalcin gene

J. Pike, M. Uchida, Keiichi Ozonco, 1997, The Journal of Steroid Biochemistry and Molecular Biology.

A 55-kilodalton accessory factor facilitates vitamin D receptor DNA binding.

K. Ozono, J. Pike, T. Sone, 1991, Molecular endocrinology.

Perspectives: The genomic mechanism of action of 1,25‐dihydroxyvitamin D3

K. Ozono, J. Pike, T. Sone, 1991, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

1,25-Dihydroxyvitamin D3 induces expression of the Wnt signaling co-regulator LRP5 via regulatory elements located significantly downstream of the gene's transcriptional start site

Sungtae Kim, J. Pike, Lee A. Zella, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

1,25-Dihydroxyvitamin D3 regulates the expression of low-density lipoprotein receptor-related protein 5 via deoxyribonucleic acid sequence elements located downstream of the start site of transcription.

Sungtae Kim, J. Pike, Lee A. Zella, 2006, Molecular endocrinology.

Dexamethasone Enhances 1α,25-Dihydroxyvitamin D3 Effects by Increasing Vitamin D Receptor Transcription*

D. Trump, Candace S. Johnson, J. Pike, 2011, The Journal of Biological Chemistry.

The human osteocalcin promoter directs bone-specific vitamin D-regulatable gene expression in transgenic mice.

R. Kesterson, F. DeMayo, F. Demayo, 1993, Molecular endocrinology.

Immunocytochemical determination of estrogen receptor, progesterone receptor, and 1,25-dihydroxyvitamin D3 receptor in breast cancer and relationship to prognosis.

M. Haussler, D. Easton, R. Coombes, 1991, Cancer research.

The human transient receptor potential vanilloid type 6 distal promoter contains multiple vitamin D receptor binding sites that mediate activation by 1,25-dihydroxyvitamin D3 in intestinal cells.

Sungtae Kim, J. Pike, M. Meyer, 2006, Molecular endocrinology.

Absence of the Vitamin D Receptor Inhibits Atherosclerotic Plaque Calcification in Female Hypercholesterolemic Mice

J. Pike, J. Jeffery, M. Onal, 2017, Journal of cellular biochemistry.

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

M. Tzukerman, M. Parker, J. Pike, 1994, Molecular endocrinology.

Transactivation properties of retinoic acid and retinoid X receptors in mammalian cells and yeast. Correlation with hormone binding and effects of metabolism.

J. Pike, M. Elgort, M. Boehm, 1993, The Journal of biological chemistry.

Class 3 semaphorins are transcriptionally regulated by 1,25(OH)2D3 in osteoblasts

J. Pike, M. Meyer, L. Verlinden, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

1,25-dihydroxyvitamin D3 modulates phosphorylation of serine 205 in the human vitamin D receptor: site-directed mutagenesis of this residue promotes alternative phosphorylation.

R. Cook, N. Weigel, J. Pike, 1994, Biochemistry.

The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets.

J. Pike, P. Malloy, D. Feldman, 1999, Endocrine reviews.

Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism

J. Pike, M. Meyer, S. Lee, 2020, JBMR plus.

Insights into the Genomic Mechanism of Action of 1,25-Dihydroxyvitamin D3

J. Pike, 1994 .

THE OSTEOCALCIN GENE AS A MOLECULAR MODEL FOR TISSUE-SPECIFIC EXPRESSION AND 1,25-DIHYDROXYVITAMIN D3 REGULATION

R. Kesterson, K. Ozono, J. Pike, 1993 .

Multifunctional enhancers regulate mouse and human vitamin D receptor gene transcription.

R. D. Nerenz, J. Pike, M. Meyer, 2010, Molecular endocrinology.

1,25‐dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3‐E1 cells by direct regulation of cystathionine β‐synthase

S. Boonen, P. Lips, N. V. van Schoor, 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cellular Responses to Hormones

J. Pike, N. Horseman, 2001 .

Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators.

Carolyn D. DuSell, Russell S. Thomas, E. Nelson, 2010, Molecular endocrinology.

Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D(3) action.

J. Pike, M. Meyer, J. Pike, 2012, Archives of biochemistry and biophysics.

Human vitamin D receptor-dependent transactivation in Saccharomyces cerevisiae requires retinoid X receptor.

J. Pike, C. H. Jin, 1996, Molecular endocrinology.

Vitamin D receptor interaction with specific DNA. Association as a 1,25-dihydroxyvitamin D3-modulated heterodimer.

J. Pike, S. Kerner, T. Sone, 1991, The Journal of biological chemistry.

1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components*

H. DeLuca, J. Pike, M. Meyer, 2015, The Journal of Biological Chemistry.

The impact of VDR expression and regulation in vivo

C. O’Brien, J. Pike, M. Meyer, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

New Approaches to Assess Mechanisms of Action of Selective Vitamin D Analogues

J. Pike, M. Meyer, 2021, International journal of molecular sciences.

Synthetic LXXLL peptide antagonize 1,25‐dihydroxyvitamin D3‐dependent transcription

J. Pike, Hironori Yamamoto, O. Barmina, 2003, Journal of cellular biochemistry.

The Vitamin D Receptor: Discovery, Structure, and Function

J. Pike, 1998 .

Analysis of regulatory regions in the COL1A1 gene responsible for 1,25‐dihydroxyvitamin D3‐mediated transcriptional repression in osteoblastic cells

D. Rowe, J. Pike, D. Pavlin, 1994, Journal of cellular biochemistry.

The mouse RANKL gene locus is defined by a broad pattern of histone H4 acetylation and regulated through distinct distal enhancers

J. Pike, M. Meyer, Melissa L. Martowicz, 2011, Journal of cellular biochemistry.

Deletion of the Distal Tnfsf11 RL‐D2 Enhancer That Contributes to PTH‐Mediated RANKL Expression in Osteoblast Lineage Cells Results in a High Bone Mass Phenotype in Mice

J. Pike, M. Onal, A. L. Danielson, 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

The parathyroid hormone-regulated transcriptome in osteocytes: parallel actions with 1,25-dihydroxyvitamin D3 to oppose gene expression changes during differentiation and to promote mature cell function.

L. Bonewald, J. Pike, M. Meyer, 2015, Bone.

New Aspects of DBP

R. Bouillon, J. Pike, C. Verboven, 2005 .

Comparison of Vitamin D Receptor ( VDR ) Content by lmmunocytology with 9 A 7 Antibody and by Calcitriol High A ~ inity Binding Capacity from Competitive Binding Studies with [ zH ] Calcitriol in Various Cell Lines

J. Pike, S. Marx, H. Deluca, 2002 .

Immunocytochemical detection of 1,25-dihydroxyvitamin D3 receptor in breast cancer.

M. Haussler, R. Coombes, J. Pike, 1987, Cancer research.

The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3

J. Pike, S. Lee, S. M. Lee, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

A humanized mouse model of hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia.

J. Goellner, C. O’Brien, J. Pike, 2014, Endocrinology.

1,25‐Dihydroxyvitamin D regulates expression of the tryptophan hydroxylase 2 and leptin genes: implication for behavioral influences of vitamin D

P. Jurutka, J. Hsieh, M. Sabir, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Saccharomyces cerevisiae Requires Retinoid X Receptor

J. Pike, C. H. Jin, 1996 .

Does Sex Make a Difference? - Sex-Neutral Nongenomic Signaling by Estrogens

J. Pike, 2001 .

CHAPTER 11 – The Vitamin D Receptor

J. Pike, N. Shevde, 2005 .

Receptors for 1,25-Dihydroxyvitamin D3: Structural Comparisons and Recent Functional Insights

M. Haussler, D. Mangelsdorf, J. Pike, 1987 .

Transcriptional control of receptor activator of nuclear factor-kappaB ligand by the protein kinase A activator forskolin and the transmembrane glycoprotein 130-activating cytokine, oncostatin M, is exerted through multiple distal enhancers.

Sungtae Kim, J. Pike, M. Yamazaki, 2007, Molecular endocrinology.

Vitamin D: Nuclear Receptor for 1,25(OH)2D3

J. Pike, N. Shevde, 2003 .

1 , 25-Dihydroxyvitamin D 3 Influences Cellular Homocysteine Levels in Murine Preosteoblastic MC 3 T 3E 1 Cells by Direct Regulation of Cystathionine b-Synthase

S. Boonen, P. Lips, R. Banerjee, 2011 .

A DNA Segment Spanning the Mouse Tnfsf11 Transcription Unit and Its Upstream Regulatory Domain Rescues the Pleiotropic Biologic Phenotype of the RANKL Null Mouse

J. Goellner, C. O’Brien, J. Pike, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Estrogen modulates the recruitment of myelopoietic cell progenitors in rat through a stromal cell-independent mechanism involving apoptosis.

J. Pike, N. Shevde, NK Shevde, 1996, Blood.

VDR/RXR and TCF4/β-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression.

J. Pike, M. Meyer, Paul D. Goetsch, 2012, Molecular endocrinology.

Enhancers located within two introns of the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3.

Sungtae Kim, J. Pike, Lee A. Zella, 2006, Molecular endocrinology.

Genetic defects of the 1,25-dihydroxyvitamin D3 receptor.

B. O’Malley, J. Pike, P. Malloy, 1991, Journal of Receptor Research.

Abnormal binding of vitamin D receptors to deoxyribonucleic acid in a kindred with vitamin D-dependent rickets, type II.

Z. Hochberg, J. Pike, P. Malloy, 1989, The Journal of clinical endocrinology and metabolism.

A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis

R. Xavier, R. Sadreyev, Thomas B. Sundberg, 2023, The Journal of clinical investigation.

A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene Cyp24a1 in renal and non-renal tissues

Glenville Jones, J. Pike, M. Meyer, 2019, The Journal of Biological Chemistry.

Inhibition of 1,25‐Dihydroxyvitamin D3‐Dependent Transcription by Synthetic LXXLL Peptide Antagonists that Target the Activation Domains of the Vitamin D and Retinoid X Receptors

J. Pike, O. Barmina, D. McDonnell, 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo

C. O’Brien, J. Pike, M. Meyer, 2021, PloS one.

Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor

Sungtae Kim, J. Pike, M. Meyer, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

Analysis of Osteocalcin Expression in Transgenic Mice Reveals a Species Difference in Vitamin D Regulation of Mouse and Human Osteocalcin Genes

R. Kesterson, F. DeMayo, J. Pike, 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Fundamentals of vitamin D hormone-regulated gene expression

J. Pike, M. Meyer, J. W. Pike, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

Monoclonal antibodies as probes in the characterization of 1,25-dihydroxyvitamin D3 receptors.

M. Haussler, J. Pike, 1986, Methods in Enzymology.

Genomic mechanisms controlling renal vitamin D metabolism

J. Pike, M. Meyer, 2023, The Journal of Steroid Biochemistry and Molecular Biology.

Supplemental Information CARM 1 Methylates Chromatin Remodeling Factor BAF 155 to Enhance Tumor Progression and Metastasis

P. Ahlquist, W. Cai, Menggang Yu, 2013 .

Genome-wide analyses of gene expression profile identify key genes and pathways involved in skeletal response to phosphate and 1,25-dihydroxyvitamin D3 in vivo

J. Pike, M. Meyer, N. Benkusky, 2023, The Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1 , 25-dihydroxyvitamin D 3 ( vitamin D response element / steroid receptor / gene activation / osteocalcin promoter / nuclear accessory factor )

K. Ozono, J. Pike, T. Sone, 2022 .

Enhancers located in the vitamin D receptor gene mediate transcriptional autoregulation by 1,25-dihydroxyvitamin D3

Sungtae Kim, J. Pike, Lee A. Zella, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

Interaction between 1,25-dihydroxyvitamin D3 receptors and intestinal nuclei. Binding to nuclear constituents in vitro.

J. Pike, 1982, The Journal of biological chemistry.

A sensitive radioreceptor assay for 1 alpha, 25-dihydroxyvitamin D in biological fluids.

M. Haussler, J. Pike, J. Chandler, 1980, Methods in Enzymology.

Vitamin D receptor cross-talk with p63 signaling promotes epidermal cell fate

J. Pike, M. Meyer, D. Bikle, 2023, The Journal of Steroid Biochemistry and Molecular Biology.

1,25-Dihydroxyvitamin D3 receptors in space-flown vs. grounded control rat kidneys.

M. Haussler, D. Mangelsdorf, S. Marion, 1985, The Physiologist.

Molecular insights into mineralotropic hormone inter-regulation

J. Pike, M. Meyer, Seong Min Lee, 2023, Frontiers in Endocrinology.

VITAMIN D3 RECEPTORS: MOLECULAR STRUCTURE OF THE PROTEIN AND ITS CHROMOSOMAL GENE

B. O’Malley, R. Kesterson, J. Pike, 1988 .

VITAMIN D RECEPTOR MUTATIONS AND HEREDITARY 1,25-DIHYDROXYVITAMIN D RESISTANT RICKETS

J. Pike, P. Malloy, D. Feldman, 1991 .

Regulation of RANKL promoter activity is associated with histone remodeling in murine bone stromal cells

Sungtae Kim, J. Rubin, T. Murphy, 2004, Journal of cellular biochemistry.

The vitamin D receptor interacts preferentially with DRIP205-like LxxLL motifs.

J. Pike, Lee A. Zella, D. McDonnell, 2007, Archives of biochemistry and biophysics.

Sujay K. Singh, J. Pike, B. Darnay, 2008, Molecular Endocrinology.

1,25-Dihydroxyvitamin D3 induced histone profiles guide discovery of VDR action sites

J. Pike, M. Meyer, N. Benkusky, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

An ochre mutation in the vitamin D receptor gene causes hereditary 1 , 25-dihydroxyvitamin D 3-resistant rickets in three families ( receptor chromosomal gene / steroid receptor / transcription / genetic disease )

B. O’Malley, Z. Hochberg, J. Pike, 2022 .

The Vitamin D3 Receptor and Its Chromosomal Gene

B. O’Malley, R. Kesterson, R. A. Scott, 1989 .