Manishha Patel

发表

Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening

Jun Liu, S. Batalov, A. Orth, 2014, BMC Cancer.

Exploring Rac GTPase regulation : the molecular mechanisms governing the DOCK180 and ELMO interaction and the role of this complex in Rac-mediated cell migration

Manishha Patel, 2011 .

Structural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)*

R. Liddington, L. Jaroszewski, B. Stec, 2010, The Journal of Biological Chemistry.

Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening

S. Batalov, A. Orth, Jennifer L. Harris, 2014, BMC Cancer.

An Evolutionarily Conserved Autoinhibitory Molecular Switch in ELMO Proteins Regulates Rac Signaling

K. Hofmann, M. Bouvier, J. Côté, 2010, Current Biology.

An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.

D. Barford, D. Komander, J. Côté, 2008, Molecular biology of the cell.

Opening up on ELMO regulation

J. Côté, Manishha Patel, Ariane Pelletier, 2011, Small GTPases.

The Arf Family GTPase Arl4A Complexes with ELMO Proteins to Promote Actin Cytoskeleton Remodeling and Reveals a Versatile Ras-binding Domain in the ELMO Proteins Family*

J. Côté, Manishha Patel, F. Lee, 2011, The Journal of Biological Chemistry.

The Invadopodia Scaffold Protein Tks5 Is Required for the Growth of Human Breast Cancer Cells In Vitro and In Vivo

W. You, Xiayu Huang, Manishha Patel, 2015, PloS one.

Ras GTPases’ interaction with effector domains

J. Côté, Manishha Patel, 2013, Communicative & integrative biology.