D. Sims

发表

Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype

Tao Liu, Jennifer L. Rohn, Norbert Perrimon, 2011, The Journal of cell biology.

PDGF/VEGF signaling controls cell size in Drosophila

B. Baum, D. Sims, P. Duchek, 2009, Genome Biology.

Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology

Tao Liu, Buzz Baum, T. Liu, 2009, Genome Biology.

The FLIGHT Drosophila RNAi database

M. Zvelebil, B. Baum, D. Sims, 2010, Fly.

Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen

A. Ashworth, M. Zvelebil, I. Kozarewa, 2011, Proceedings of the National Academy of Sciences.

Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.

Alan Ashworth, James Campbell, Kerry Fenwick, 2014, Cancer research.

ROCK: a breast cancer functional genomics resource

Borisas Bursteinas, Marketa Zvelebil, Costas Mitsopoulos, 2010, Breast Cancer Research and Treatment.

An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor.

Marketa Zvelebil, Stuart M Haslam, Anne Dell, 2014, Cancer discovery.

Hippo Stabilises Its Adaptor Salvador by Antagonising the HECT Ubiquitin Ligase Herc4

N. Tapon, D. Sims, B. Aerne, 2015, PloS one.

Functional Role of Matrix Metalloproteinase-8 in Stem/Progenitor Cell Migration and Their Recruitment Into Atherosclerotic Lesions

Qingbo Xu, M. Mayr, S. Ye, 2013, Circulation research.

Parallel high-throughput RNA interference screens identify PINK1 as a potential therapeutic target for the treatment of DNA mismatch repair-deficient cancers.

A. Ashworth, C. Lord, D. Sims, 2011, Cancer research.

Integrative molecular and functional profiling of ERBB2-amplified breast cancers identifies new genetic dependencies

A. Ashworth, H. Horlings, J. Reis-Filho, 2014, Oncogene.

Comprehensive Genomic Analysis of a BRCA2 Deficient Human Pancreatic Cancer

A. Ashworth, M. Zvelebil, I. Kozarewa, 2011, PloS one.

Functional viability profiles of breast cancer.

Alan Mackay, Alan Ashworth, Daniel Wetterskog, 2011, Cancer discovery.

High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing

Marketa Zvelebil, Alan Ashworth, Costas Mitsopoulos, 2011, Genome Biology.

Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor

A. Ashworth, M. Zvelebil, Dafydd G. Thomas, 2012, Breast Cancer Research and Treatment.

Genomic distance entrained clustering and regression modelling highlights interacting genomic regions contributing to proliferation in breast cancer

David Sims, Marketa Zvelebil, Alan Mackay, 2010, BMC Systems Biology.

Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype

N. Perrimon, A. Kiger, J. Rohn, 2011, Journal of Cell Biology.

FLIGHT: database and tools for the integration and cross-correlation of large-scale RNAi phenotypic datasets

David Sims, Qiong Gao, Borisas Bursteinas, 2005, Nucleic Acids Res..

Smooth Muscle Cell Differentiation from Embryonic Stem Cells: Role of HDAC7 and PDGF-BB

D. Sims, Q. Xiao, 2012 .

Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity.

A. Ashworth, S. Hooper, R. Natrajan, 2014, Cancer research.

An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor.

A. Ashworth, M. Zvelebil, N. Orr, 2014, Cancer discovery.