Chunming Liu

发表

Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling

J. Jia, Jiandang Shi, Yajuan Liu, 2015, Molecular and Cellular Biology.

Klf4 Interacts Directly with Oct4 and Sox2 to Promote Reprogramming

Wange Lu, M. Pera, Kouichi Hasegawa, 2009, Stem cells.

Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis.

T. Wang, Tianxin Yu, Chunming Liu, 2012, Carcinogenesis.

CD151-α3β1 integrin complexes are prognostic markers of glioblastoma and cooperate with EGFR to drive tumor cell motility and invasion

R. Segal, C. Horbinski, O. Thibault, 2015, Oncotarget.

Kruppel like factor KLF4 facilitates cutaneous wound healing by promoting fibrocyte generation from myeloid-derived suppressor cells

M. Nagarkatti, P. Nagarkatti, Ying Shi, 2015, The Journal of investigative dermatology.

Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4).

Michael V. Fiandalo, J. Mohler, D. Watt, 2017, Organic & biomolecular chemistry.

Analysis of trans-2,6-difluoro-4′-(N,N-dimethylamino)stilbene (DFS) in biological samples by liquid chromatography-tandem mass spectrometry: metabolite identification and pharmacokinetics

D. Watt, Chunming Liu, Hai‐Shu Lin, 2015, Analytical and Bioanalytical Chemistry.

Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells.

X. Chen, Xi He, Wen Zhang, 2006, The Journal of biological chemistry.

Protocol for rapid assessment of the efficacy of novel Wnt inhibitors using zebrafish models

Chunming Liu, Jessica S. Blackburn, J. Blackburn, 2021, STAR protocols.

Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors.

Eun Ryoung Jang, Chi Wang, H. Weiss, 2013, Carcinogenesis.

2′,6′-Dihalostyrylanilines, Pyridines, and Pyrimidines for the Inhibition of the Catalytic Subunit of Methionine S-Adenosyltransferase-2

L. Dwoskin, D. Watt, O. Tsodikov, 2014, Journal of medicinal chemistry.

Deficiency of KLF 4 compromises the lung function in an acute mouse model of allergic asthma

P. Nagarkatti, Chunming Liu, Daping Fan, 2018 .

Deficiency of KLF4 compromises the lung function in an acute mouse model of allergic asthma.

M. Nagarkatti, P. Nagarkatti, Chunming Liu, 2017, Biochemical and biophysical research communications.

Pictet-Spengler condensations using 4-(2-aminoethyl)coumarins.

Michael V. Fiandalo, J. Mohler, C. Zhan, 2020, New journal of chemistry = Nouveau journal de chimie.

Application of Mannich bases to the synthesis of hydroxymethylated isoflavonoids as potential antineoplastic agents.

J. Mohler, D. Watt, Wen Zhang, 2015, Organic & biomolecular chemistry.

TRIM56 Is a Virus- and Interferon-Inducible E3 Ubiquitin Ligase That Restricts Pestivirus Infection

Kui Li, Jie Wang, Baoming Liu, 2011, Journal of Virology.

Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection

C. Zhan, F. Zheng, R. Perera, 2022, PloS one.

A Benzenesulfonamide-Based Mitochondrial Uncoupler Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Epithelial Ovarian Cancer

Wen Zhang, Chunming Liu, Fangfang Bi, 2021, Molecular Cancer Therapeutics.

Diaminobutoxy-substituted Isoflavonoid (DBI-1) Enhances the Therapeutic Efficacy of GLUT1 inhibitor BAY-876 by Modulating Metabolic Pathways in Colon Cancer Cells.

B. Evers, Wen Zhang, Chunming Liu, 2022, Molecular cancer therapeutics.

Anti-neoplastic sulfonamides alter the metabolic homeostasis and disrupt the suppressor activity of regulatory T cells

B. Evers, Aman Khurana, Chunming Liu, 2022, Scientific Reports.

Krüppel-like Factor 4 Is Acetylated by p300 and Regulates Gene Transcription via Modulation of Histone Acetylation*

X. Chen, K. Bhakat, Wen Zhang, 2007, Journal of Biological Chemistry.

N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells.

D. Watt, Wen Zhang, Chunming Liu, 2015, Bioorganic & medicinal chemistry letters.

Synthesis and tautomerization of hydroxylated isoflavones bearing heterocyclic hemi-aminals.

D. Watt, Chunming Liu, V. Khilya, 2015, Organic & biomolecular chemistry.

Arylquins Target Vimentin to Trigger Par-4 Secretion for Tumor Cell Apoptosis

V. Rangnekar, A. Hamza, C. Zhan, 2014, Nature chemical biology.

Semisynthetic aurones A14 protects against T-cell acute lymphoblastic leukemia via suppressing proliferation and inducing cell cycle arrest with apoptosis

M. Wang, Jiayi Zhang, Chunming Liu, 2022, Chinese medicine.

Halogenated diarylacetylenes repress c-myc expression in cancer cells.

C. Zhan, D. Watt, Wen Zhang, 2014, Bioorganic & medicinal chemistry letters.

Antineoplastic Isoflavonoids Derived from Intermediate ortho‐Quinone Methides Generated from Mannich Bases

Michael V. Fiandalo, J. Mohler, D. Watt, 2016, ChemMedChem.

Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues.

J. Thorson, J. Rohr, A. Morris, 2014, Angewandte Chemie.

Developing Quinoline-based Secretagogues for Prostate Apoptosis Response-4 Protein (Par-4) as Potential Antineoplastic Agents

R. Burikhanov, Chunming Liu, Vitaliy M. Sviripa, 2021, Tumor Suppressor Par-4.

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

J. Chen, L. Dwoskin, C. Zhan, 2019, Scientific Reports.

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

J. Chen, L. Dwoskin, C. Zhan, 2019, Scientific Reports.

Adenomatous Polyposis Coli (APC) Differentially Regulates β-Catenin Phosphorylation and Ubiquitination in Colon Cancer Cells*

Xi He, Wen Zhang, Chunming Liu, 2006, Journal of Biological Chemistry.

Krüppel-like Factor 4 Regulates Intestinal Epithelial Cell Morphology and Polarity

X. Chen, R. Xu, T. Wang, 2011, PloS one.

Neurotensin, a novel target of Wnt/β‐catenin pathway, promotes growth of neuroendocrine tumor cells

H. Weiss, B. Evers, Chunming Liu, 2015, International journal of cancer.

proliferation -catenin and cell β -GlcNAcylation drive the expression of O The hexosamine biosynthetic pathway and

T. Lefebvre, C. Guinez, A. Mir, 2013 .

The hexosamine biosynthetic pathway and O-GlcNAcylation drive the expression of β-catenin and cell proliferation.

T. Lefebvre, C. Guinez, A. Mir, 2012, American journal of physiology. Endocrinology and metabolism.

the expression of β-catenin and cell proliferation

T. Lefebvre, C. Guinez, Stéphanie Olivier, 2011 .

KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract.

Chunming Liu, D. Pritchard, D Mark Pritchard, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Kruppel-like Factor 4 (Klf4) Prevents Embryonic Stem (ES) Cell Differentiation by Regulating Nanog Gene Expression*

Yang Yang, Wange Lu, Chunming Liu, 2010, The Journal of Biological Chemistry.

Regulation of Ketogenic Enzyme HMGCS2 by Wnt/β-catenin/PPARγ Pathway in Intestinal Cells

H. Weiss, Yuning Zhou, B. Evers, 2019, Cells.

Regulation of Induced Pluripotent Stem (iPS) Cell Induction by Wnt/β-Catenin Signaling*

S. Bellusci, Wen-Hsuan Chang, Chunming Liu, 2014, The Journal of Biological Chemistry.

KLF4 gene expression is inhibited by the Notch signaling pathway that controls goblet cell differentiation in mouse GI tract

Chunming Liu, D. Pritchard, Hai Zheng, 2008 .

Phenylethynyl-substituted Heterocycles Inhibit Cyclin D1 and Induce the Expression of Cyclin-dependent Kinase Inhibitor p21Wif1/Cip1 in Colorectal Cancer Cells.

C. Zhan, D. Watt, Wen Zhang, 2018, MedChemComm.

PR55α, a Regulatory Subunit of PP2A, Specifically Regulates PP2A-mediated β-Catenin Dephosphorylation

X. Chen, J. Jia, Yajuan Liu, 2009, The Journal of Biological Chemistry.

Deptor Is a Novel Target of Wnt/β-Catenin/c-Myc and Contributes to Colorectal Cancer Cell Growth.

Chi Wang, Jinpeng Liu, H. Weiss, 2018, Cancer research.

Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression.

X. Chen, D. Watt, B. Evers, 2011, Journal of medicinal chemistry.

Deletion of tetraspanin CD151 alters the Wnt oncogene-induced mammary tumorigenesis: A cell type-linked function and signaling

K. Chen, Chi Wang, Jinpeng Liu, 2019, Neoplasia.

Epigenetic Regulation of Wnt Signaling by Carboxamide-Substituted Benzhydryl Amines that Function as Histone Demethylase Inhibitors

C. Zhan, D. Watt, Tianxin Yu, 2020, iScience.

Regulation of the Potential Marker for Intestinal Cells, Bmi1, by β-Catenin and the Zinc Finger Protein KLF4

H. Weiss, Eun Y. Lee, B. Evers, 2011, The Journal of Biological Chemistry.

Development of 6H-Chromeno[3,4-c]pyrido[3',2':4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 Secretagogues.

V. Rangnekar, D. Watt, R. Burikhanov, 2015, Tetrahedron letters.

CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling

Q. She, R. Drapkin, Chi Wang, 2014, Oncotarget.

CD 151-α 3 β 1 Integrin Complexes Suppress Ovarian Tumor Growth by Repressing Slug-Mediated EMT and Canonical Wnt Signaling

John, Q. She, Chi Wang, 2014 .

BRD4 modulates vulnerability of triple-negative breast cancer to targeting of integrin-dependent signaling pathways

Chi Wang, O. Thibault, B. Zhou, 2020, Cellular Oncology.

Multifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesis.

D. Watt, Xuehe Xu, Chunming Liu, 2015, Acta biochimica et biophysica Sinica.

Thymine DNA Glycosylase Is a Positive Regulator of Wnt Signaling in Colorectal Cancer*

X. Chen, Chi Wang, Jiandang Shi, 2014, The Journal of Biological Chemistry.

Potent Synergistic Effect on C-Myc–Driven Colorectal Cancers Using a Novel Indole-Substituted Quinoline with a Plk1 Inhibitor

Chi Wang, Eun Y. Lee, Daheng He, 2021, Molecular Cancer Therapeutics.

Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents

V. Rangnekar, R. Guy, D. Watt, 2021, Journal of medicinal chemistry.

A Direct Synthesis of 2‐(ω‐Carboxyalkyl)isoflavones from ortho ‐Hydroxylated Deoxybenzoins

J. Mohler, D. Watt, Chunming Liu, 2018, European Journal of Organic Chemistry.

Characterization of Squamous Cell Lung Cancers from Appalachian Kentucky

Sally R. Ellingson, Nathan L. Vanderford, Heidi L. Weiss, 2018, Cancer Epidemiology, Biomarkers & Prevention.

Autophagic flux modulation by Wnt/β-catenin pathway inhibition in hepatocellular carcinoma

D. Watt, Chunming Liu, Jieyun Jiang, 2019, PloS one.

Xom, a ventralizing factor, regulates beta‐catenin levels and cell fate

Chunming Liu, Yanqi Xie, 2018, FEBS letters.

Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation

D. Watt, B. Evers, Chunming Liu, 2019, PloS one.

Induction of AMPK activation by N,N’-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers

D. Watt, H. Weiss, B. Evers, 2018, bioRxiv.

CD151 represses mammary gland development by maintaining the niches of progenitor cells

B. Zhou, Chunming Liu, Yadi Wu, 2014, Cell cycle.

Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin.

L. Dwoskin, V. Rangnekar, C. Zhan, 2016, Organic & biomolecular chemistry.

An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors.

C. Zhan, D. Watt, B. Evers, 2019, Journal of medicinal chemistry.

Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma

J. Zwischenberger, D. Watt, B. Evers, 2020, Oncotarget.

Fluorinated N,N-dialkylaminostilbenes repress colon cancer by targeting methionine S-adenosyltransferase 2A.

Xi Chen, Chang-Guo Zhan, Adel Hamza, 2013, ACS chemical biology.

Fluorinated N,N'-diarylureas as AMPK activators.

D. Watt, Wen Zhang, Chunming Liu, 2013, Bioorganic & medicinal chemistry letters.

Kruppel-like factor 4-dependent Staufen1-mediated mRNA decay regulates cortical neurogenesis

Jiandang Shi, Chunming Liu, Byoung-San Moon, 2018, Nature Communications.

Potential protein markers for breast cancer recurrence: a retrospective cohort study

V. Rangnekar, Chi Wang, B. Zhou, 2018, Cancer Causes & Control.

Abstract 992: PR55alpha, a regulatory subunit of PP2A, specifically regulates PP2A-mediated beta-catenin dephosphorylation

J. Jia, Wen Zhang, Tianxin Yu, 2010 .

Efficient synthesis of aurone Mannich bases and evaluation of their antineoplastic activity in PC-3 prostate cancer cells

Michael V. Fiandalo, J. Mohler, D. Watt, 2018, Chemical Papers.

Fluorinated N,N'-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells

H. Weiss, B. Evers, Chunming Liu, 2017, Molecular Cancer Therapeutics.

Chromatin silencing maintains the identity of intestinal stem cells.

Tianxin Yu, Chunming Liu, 2016, Stem cell investigation.

Chalcone Derivative CX258 Suppresses Colorectal Cancer via Inhibiting the TOP2A/Wnt/β-Catenin Signaling

Wei Wang, Wen Zhang, Chunming Liu, 2023, Cells.

Genomic screening methodology not requiring barcoding: Single nucleotide polymorphism-based, mixed-cell screening (SMICS).

Jinpeng Liu, Wen Zhang, Chunming Liu, 2023, Genomics.

Zebrafish Drug Screening Identifies Erlotinib as an Inhibitor of Wnt/β-Catenin Signaling and Self-Renewal in T-cell Acute Lymphoblastic Leukemia

Wen Zhang, Chunming Liu, Jessica S. Blackburn, 2023, bioRxiv.