K. Heo

发表

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

Dongsup Kim, V. Wood, J. Hayles, 2010, Nature Biotechnology.

Role for SUMOylation in disturbed flow-induced atherosclerotic plaque formation

J. Abe, K. Heo, N. Le, 2015 .

Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals: Implications for Atherogenesis

J. Taunton, M. Doyley, G. Schifitto, 2019, Circulation.

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

C. Reinhart-King, K. Fujiwara, M. King, 2011, The Journal of cell biology.

Disturbed flow-induced FAK K152 SUMOylation initiates the formation of pro-inflammation positive feedback loop by inducing reactive oxygen species production in endothelial cells.

K. Fujiwara, K. Heo, N. Le, 2021, Free radical biology & medicine.

Inhibition of p90RSK activation sensitizes triple-negative breast cancer cells to cisplatin by inhibiting proliferation, migration and EMT

K. Kang, C. Myung, K. Heo, 2019, BMB reports.

Identification of Activators of ERK5 Transcriptional Activity by High-Throughput Screening and the Role of Endothelial ERK5 in Vasoprotective Effects Induced by Statins and Antimalarial Agents

K. Fujiwara, J. Abe, M. Akaike, 2014, The Journal of Immunology.

Anti-apoptotic effects of autophagy via ROS regulation in microtubule-targeted and PDGF-stimulated vascular smooth muscle cells

C. Myung, K. Heo, Sang-Hyuk Jung, 2018, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Rubiarbonone C inhibits platelet‐derived growth factor‐induced proliferation and migration of vascular smooth muscle cells through the focal adhesion kinase, MAPK and STAT3 Tyr705 signalling pathways

C. Myung, K. Heo, Khong Trong Quan, 2017, British journal of pharmacology.

Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein.

J. Taunton, J. Cooke, K. Fujiwara, 2019, JCI insight.

Cytokine‐induced apoptosis inhibitor 1 (CIAPIN1) accelerates vascular remodelling via p53 and JAK2‐STAT3 regulation in vascular smooth muscle cells

C. Myung, K. Heo, Joo-Hui Han, 2021, British journal of pharmacology.

Glucagon-Like Peptide-1 and its Cardiovascular Effects

K. Fujiwara, J. Abe, K. Heo, 2012, Current Atherosclerosis Reports.

Glycoprotein isolated from Ulmus davidiana Nakai inhibits TPA-induced apoptosis through nuclear factor-kappa B in NIH/3T3 cells.

K. Heo, P. Oh, Sei-Jung Lee, 2004, Toxicology letters.

Regulation of post-translational modification in breast cancer treatment

K. Heo, 2019, BMB reports.

Antioxidative effects of glycoprotein isolated from Solanum nigrum L.

K. Heo, K. Lim, 2003, Journal of medicinal food.

Glycoprotein isolated from Solanum nigrum L. modulates the apoptotic-related signals in 12-O-tetradecanoylphorbol 13-acetate-stimulated MCF-7 cells.

K. Heo, K. Lim, 2005, Journal of medicinal food.

Ginsenoside Rh1 Induces MCF-7 Cell Apoptosis and Autophagic Cell Death through ROS-Mediated Akt Signaling

C. Myung, K. Heo, D. Huynh, 2021, Cancers.

p90RSK Activation Promotes Epithelial-Mesenchymal Transition in Cisplatin-Treated Triple-Negative Breast Cancer Cells

K. Heo, Yujin Jin, 2019, Journal of Bacteriology and Virology.

Novel role of C terminus of Hsc70‐interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5‐mediated degradation of inducible cAMP early repressor

C. Molina, C. Patterson, Chen Yan, 2010 .

C. Molina, C. Patterson, Chen Yan, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hepatoprotective effects of an Acer tegmentosum Maxim extract through antioxidant activity and the regulation of autophagy.

C. Myung, K. Heo, InWha Park, 2019, Journal of ethnopharmacology.

LPS-stimulated Macrophage Activation Affects Endothelial Dysfunction

K. Heo, Naehwan Baek, Sohyun Sim, 2018 .

Cytotoxic effect of glycoprotein isolated from Solanum nigrum L. through the inhibition of hydroxyl radical-induced DNA-binding activities of NF-kappa B in HT-29 cells.

K. Heo, Sei-Jung Lee, K. Lim, 2004, Environmental toxicology and pharmacology.

PKC (cid:1) decreases eNOS protein stability via inhibitory phosphorylation of ERK5

Jian-Dong Li, K. Fujiwara, J. Lim, 2010 .

Regulation of autophagy by controlling Erk1/2 and mTOR for platelet-derived growth factor-BB-mediated vascular smooth muscle cell phenotype shift.

C. Myung, K. Heo, Joo-Hui Han, 2021, Life sciences.

Inhibition of Proliferation of Vascular Smooth Muscle Cells by Cucurbitanes from Momordica charantia.

C. Myung, K. Heo, M. Na, 2017, Journal of natural products.

Therapeutic Effects of Ginsenosides on Vascular Smooth Muscle Cell Phenotypic Switching in Vascular Diseases

K. Heo, D. Huynh, 2022, CardioMetabolic Syndrome Journal.

Ginsenoside Rh1 inhibits tumor growth in MDA-MB-231 breast cancer cells via mitochondrial ROS and ER stress-mediated signaling pathway

K. Heo, D. Huynh, Yujin Jin, 2022, Archives of Pharmacal Research.

Protective effects of ginsenoside-Rg2 and -Rh1 on liver function through inhibiting TAK1 and STAT3-mediated inflammatory activity and Nrf2/ARE-mediated antioxidant signaling pathway

K. Heo, D. Huynh, Yujin Jin, 2021, Archives of Pharmacal Research.

Inhibition of Collagen-Induced Platelet Aggregation by the Secobutanolide Secolincomolide A from Lindera obtusiloba Blume

Jung-Jin Lee, Y. H. Kim, C. Myung, 2017, Front. Pharmacol..

Alleviation of ascorbic acid-induced gastric high acidity by calcium ascorbate in vitro and in vivo

Jeong-Sook Park, C. Myung, K. Heo, 2017, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

ERK5 Activation in Macrophages Promotes Efferocytosis and Inhibits Atherosclerosis

K. Fujiwara, J. Abe, C. Woo, 2014, Circulation.

Inhibitory effects of 6′-sialyllactose on angiotensin II-induced proliferation, migration, and osteogenic switching in vascular smooth muscle cells

Lila Kim, K. Heo, Yujin Jin, 2022, Archives of Pharmacal Research.

Antioxidative effects of glycoprotein isolated from Solanum nigrum L.

K. Heo, K. Lim, 2003, Journal of medicinal food.

Ginsenoside-Rg2 affects cell growth via regulating ROS-mediated AMPK activation and cell cycle in MCF-7 cells.

K. Heo, D. Huynh, Naehwan Baek, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Therapeutic effects of celecoxib polymeric systems in rat models of inflammation and adjuvant-induced rheumatoid arthritis.

Jeong-Sook Park, C. Myung, K. Heo, 2020, Materials science & engineering. C, Materials for biological applications.

Ginsenoside-Rg2 exerts anti-cancer effects through ROS-mediated AMPK activation associated mitochondrial damage and oxidation in MCF-7 cells

C. Myung, K. Heo, Yujin Jin, 2021, Archives of Pharmacal Research.

Inhibitory Effect of Ginsenosides Rh1 and Rg2 on Oxidative Stress in LPS-Stimulated RAW 264.7 Cells

C. Myung, K. Heo, Yujin Jin, 2018 .

Sodium propionate exerts anticancer effect in mice bearing breast cancer cell xenograft by regulating JAK2/STAT3/ROS/p38 MAPK signaling

C. Myung, K. Heo, Joo-Hui Han, 2020, Acta Pharmacologica Sinica.

PPARgamma activation abolishes LDL-induced proliferation of human aortic smooth muscle cells via SOD-mediated down-regulation of superoxide.

K. Hoe, Dong-Uk Kim, C. Myung, 2007, Biochemical and biophysical research communications.

Ginsenoside Rh1 protects human endothelial cells against lipopolysaccharide-induced inflammatory injury through inhibiting TLR2/4-mediated STAT3, NF-κB, and ER stress signaling pathways.

C. Myung, K. Heo, Yujin Jin, 2022, Life sciences.

Therapeutic effects of ginsenosides on breast cancer growth and metastasis

K. Heo, D. Huynh, Yujin Jin, 2020, Archives of Pharmacal Research.

Correction: Inhibitory Effect of Ginsenosides Rh1 and Rg2 on Oxidative Stress in LPS-Stimulated RAW 264.7 Cells

C. Myung, K. Heo, Yujin Jin, 2019, Journal of Bacteriology and Virology.

Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function.

J. Taunton, E. Yeh, K. Fujiwara, 2015, The Journal of clinical investigation.

Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events.

J. Abe, B. Berk, K. Heo, 2016, Antioxidants & redox signaling.

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

P. Bourne, Lin-Feng Chen, Tomoaki Koga, 2012, Nature Communications.

De-SUMOylation Enzyme of Sentrin/SUMO-Specific Protease 2 Regulates Disturbed Flow–Induced SUMOylation of ERK5 and p53 that Leads to Endothelial Dysfunction and Atherosclerosis

Keigi Fujiwara, Edward T H Yeh, E. Yeh, 2013, Circulation research.

A Crucial Role for p90RSK-Mediated Reduction of ERK5 Transcriptional Activity in Endothelial Dysfunction and Atherosclerosis

Michael S. Cohen, J. Taunton, K. Fujiwara, 2013, Circulation.

Glycoprotein isolated from Solanum nigrum L. inhibits the DNA-binding activities of NF-kappaB and AP-1, and increases the production of nitric oxide in TPA-stimulated MCF-7 cells.

K. Heo, J. Ko, S. Lee, 2004, Toxicology in vitro : an international journal published in association with BIBRA.

Phosphorylation of Protein Inhibitor of Activated STAT1 (PIAS1) by MAPK-Activated Protein Kinase-2 Inhibits Endothelial Inflammation via Increasing Both PIAS1 Transrepression and SUMO E3 Ligase Activity

K. Fujiwara, J. Abe, C. Woo, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Role of mitochondrial dynamics and mitophagy of vascular smooth muscle cell proliferation and migration in progression of atherosclerosis

K. Heo, D. Huynh, 2021, Archives of Pharmacal Research.

Role for SUMOylation in disturbed flow-induced atherosclerotic plaque formation

J. Abe, K. Heo, N. Le, 2015, Biomedical Engineering Letters.

Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction.

K. Fujiwara, J. Abe, K. Heo, 2011, Circulation journal : official journal of the Japanese Circulation Society.

Activation of PKCbeta(II) and PKCtheta is essential for LDL-induced cell proliferation of human aortic smooth muscle cells via Gi-mediated Erk1/2 activation and Egr-1 upregulation.

K. Hoe, Dong-Uk Kim, C. Myung, 2008, Biochemical and biophysical research communications.

Effects of combination therapy with candesartan and ramipril on hypertension and related complications

C. Myung, K. Heo, Sang-Hyuk Jung, 2017, Journal of Pharmaceutical Investigation.

Cucurbitane Triterpenoids from the Fruits of Momordica Charantia Improve Insulin Sensitivity and Glucose Homeostasis in Streptozotocin‐Induced Diabetic Mice

C. Myung, K. Heo, Khong Trong Quan, 2018, Molecular nutrition & food research.

Therapeutic targets for endothelial dysfunction in vascular diseases

K. Heo, D. Huynh, 2019, Archives of Pharmacal Research.

PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5.

Jian-Dong Li, K. Fujiwara, J. Lim, 2010, Blood.

Therapeutic targets and drugs for hyper-proliferation of vascular smooth muscle cells

K. Heo, D. Huynh, Yujin Jin, 2019, Journal of Pharmaceutical Investigation.

Shear Stress and Atherosclerosis

Keigi Fujiwara, K. Fujiwara, J. Abe, 2014, Molecules and cells.

MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation.

K. Fujiwara, J. Abe, C. Woo, 2011, Blood.

6′-Sialylactose abolished lipopolysaccharide-induced inflammation and hyper-permeability in endothelial cells

C. Myung, K. Heo, D. Van Nguyen, 2022, Archives of Pharmacal Research.

Rosuvastatin Inhibits the Apoptosis of Platelet-Derived Growth Factor–Stimulated Vascular Smooth Muscle Cells by Inhibiting p38 via Autophagy

C. Myung, K. Heo, Joo-Hui Han, 2021, The Journal of Pharmacology and Experimental Therapeutics.

p90RSK Targets the ERK5-CHIP Ubiquitin E3 Ligase Activity in Diabetic Hearts and Promotes Cardiac Apoptosis and Dysfunction

J. Taunton, C. Molina, C. Patterson, 2012, Circulation research.

Cream formulation improved skin-lightening effect of ginsenoside Rh1, Rg2, and Hydrangea macrophylla flower extract

K. Heo, J. Park, Dong-Hyun Kim, 2023, Journal of Pharmaceutical Investigation.

Ginsenoside Rh1 ameliorates the asthma and allergic inflammation via inhibiting Akt, MAPK, and NF-κB signaling pathways in vitro and in vivo.

H. Son, K. Heo, Ji-Yun Lee, 2023, Life sciences.

Cl- -channel is essential for LDL-induced cell proliferation via the activation of Erk1/2 and PI3k/Akt and the upregulation of Egr-1 in human aortic smooth muscle cells.

K. Hoe, Dong-Uk Kim, C. Myung, 2008, Molecules and cells.

Experimental model and novel therapeutic targets for non-alcoholic fatty liver disease development

K. Heo, Yujin Jin, 2023, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Inhibition of p90RSK is critical to abolish Angiotensin II-induced rat aortic smooth muscle cell proliferation and migration.

C. Myung, K. Heo, D. Huynh, 2019, Biochemical and biophysical research communications.

Ginsenoside Rh1 Inhibits Angiotensin II-Induced Vascular Smooth Muscle Cell Migration and Proliferation through Suppression of the ROS-Mediated ERK1/2/p90RSK/KLF4 Signaling Pathway

C. Myung, K. Heo, D. Van Nguyen, 2022, Antioxidants.

Protective effects of ginsenoside-Rg2 and -Rh1 on liver function through inhibiting TAK1 and STAT3-mediated inflammatory activity and Nrf2/ARE-mediated antioxidant signaling pathway

K. Heo, D. Huynh, Yujin Jin, 2021, Archives of Pharmacal Research.

Ginsenoside Rh1 Prevents Migration and Invasion through Mitochondrial ROS-Mediated Inhibition of STAT3/NF-κB Signaling in MDA-MB-231 Cells

C. Myung, K. Heo, D. Huynh, 2021, International journal of molecular sciences.

Minor Ginsenoside Rg2 and Rh1 Attenuates LPS-Induced Acute Liver and Kidney Damages via Downregulating Activation of TLR4-STAT1 and Inflammatory Cytokine Production in Macrophages

C. Myung, K. Heo, D. Huynh, 2020, International journal of molecular sciences.

PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation

C. Reinhart-King, K. Fujiwara, M. King, 2011, The Journal of cell biology.