M. Galas

发表

Emerging Connections Between Tau and Nucleic Acids.

L. Buée, B. Lefebvre, M. Galas, 2019, Advances in experimental medicine and biology.

Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology

H. Soininen, L. Buée, J. Lambert, 2016, Molecular Psychiatry.

Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration.

Luc Buée, L. Buée, S. Hébert, 2010, Human molecular genetics.

Insight in the exocytotic process in chromaffin cells: regulation by trimeric and monomeric G proteins.

S. Chasserot-Golaz, N. Vitale, M. Bader, 2000, Biochimie.

Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

L. Rasmussen, J. Lundeberg, Yue Wang, 2020, iScience.

The peptidyl prolyl cis/trans isomerase Pin1 downregulates the Inhibitor of Apoptosis Protein Survivin.

L. Buée, K. Ando, M. Galas, 2007, Biochimica et biophysica acta.

Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly

L. Buée, V. Buchman, M. Galas, 2017, Cell Death & Disease.

Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy

L. Buée, V. Bohr, B. Lefebvre, 2020, Acta Neuropathologica Communications.

Increased Alix (apoptosis-linked gene-2 interacting protein X) immunoreactivity in the degenerating striatum of rats chronically treated by 3-nitropropionic acid

S. Schiffmann, D. Blum, M. Galas, 2004, Neuroscience Letters.

Chronic intoxication with 3-nitropropionic acid in rats induces the loss of striatal dopamine terminals without affecting nigral cell viability

S. Schiffmann, D. Blum, M. Galas, 2004, Neuroscience Letters.

Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast.

J. Winderickx, F. Madeo, M. Galas, 2011, Biochemical Society transactions.

Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics

David Blum, S. Schiffmann, R. Hourez, 2003, The Lancet Neurology.

Altered Neuronal Excitability in Cerebellar Granule Cells of Mice Lacking Calretinin

Egidio D'Angelo, David Gall, Stéphane Schurmans, 2003, The Journal of Neuroscience.

Presence of Dynamin—Syntaxin Complexes Associated with Secretory Granules in Adrenal Chromaffin Cells

S. Chasserot-Golaz, M. Bader, M. Galas, 2000, Journal of neurochemistry.

Tau/DDX6 interaction increases microRNA activity.

L. Buée, D. Weil, H. Drobecq, 2018, Biochimica et biophysica acta. Gene regulatory mechanisms.

Novel Lipidized Analog of Prolactin-Releasing Peptide Improves Memory Impairment and Attenuates Hyperphosphorylation of Tau Protein in a Mouse Model of Tauopathy.

D. Blum, M. Galas, V. Pražienková, 2018, Journal of Alzheimer's disease : JAD.

Anorexigenic lipopeptides ameliorate central insulin signaling and attenuate tau phosphorylation in hippocampi of mice with monosodium glutamate-induced obesity.

M. Galas, M. Haluzík, B. Železná, 2015, Journal of Alzheimer's disease : JAD.

The Peptidylprolyl cis/trans-Isomerase Pin1 Modulates Stress-induced Dephosphorylation of Tau in Neurons

L. Buée, D. Blum, K. Ando, 2006, Journal of Biological Chemistry.

Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo

L. Buée, B. Lefebvre, R. Kayed, 2015, Neurobiology of Disease.

Loss of Tau protein affects the structure, transcription and repair of neuronal pericentromeric heterochromatin

L. Buée, B. Lefebvre, F. Nesslany, 2016, Scientific Reports.

A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions

L. Buée, B. Lefebvre, F. Nesslany, 2014, Front. Cell. Neurosci..

Modification of receptor selectivity and functional activity of cyclic cholecystokinin analogues

Jean Martinez, M. Galas, M. Amblard, 1998 .

Pharmacological characterization of new cholecystokinin analogues.

M. Galas, J. Slaninová, L. Maletínská, 1992, European journal of pharmacology.

Identification of a Plasma Membrane-associated Guanine Nucleotide Exchange Factor for ARF6 in Chromaffin Cells

N. Vitale, M. Bader, M. Galas, 2000, The Journal of Biological Chemistry.

Regulated Exocytosis in Chromaffin Cells

D. Aunis, N. Vitale, M. Bader, 1998, The Journal of Biological Chemistry.

Regulated Exocytosis in Chromaffin Cells

J. Helms, D. Aunis, N. Vitale, 1997, The Journal of Biological Chemistry.

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker

L. Buée, I. Landrieu, G. Lippens, 2013, Neurobiology of Aging.

REGULATION OF PHOSPHOLIPASE C-13 ISOENZYMES

T. K. Harden, A. Paterson, T. Filtz, 1996 .

Regulation of Phospholipase C-β Isoenzymes

T. K. Harden, A. Paterson, T. Filtz, 1996 .

Receptor-induced heterologous desensitization of receptor-regulated phospholipase C.

T. K. Harden, M. Galas, T. Harden, 1995, European journal of pharmacology.

In Vivo Hyperthermic Stress Model: An Easy Tool to Study the Effects of Oxidative Stress on Neuronal Tau Functionality in Mouse Brain.

L. Buée, M. Galas, L. Delattre, 2017, Methods in molecular biology.

Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response

X. Montagutelli, M. Galas, E. Bonnefoy, 2022, Journal of neuroinflammation.

Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism: possible implication for Alzheimer’s disease

L. Buée, T. Voet, V. Deramecourt, 2022, Progress in Neurobiology.

Structure-activity relationship studies on cholecystokinin: analogues with partial agonist activity.

M. Galas, C. Mendre, P. Fulcrand, 1988, The American journal of physiology.

Synthetic CCKS Analogs with Antagonist Activity on Pancreatic Receptors: In Vivo Study in the Rat, Compared to Non‐Peptidic Antagonists

C. Rozé, M. Galas, J. Martinez, 1991, Pancreas.

Synthesis and biological activities of pseudopeptide analogues of the C-terminal heptapeptide of cholecystokinin. On the importance of the peptide bonds.

M. Galas, C. Mendre, A. Aumelas, 1987, Journal of medicinal chemistry.

A synthetic peptide derivative that is a cholecystokinin receptor antagonist.

M. Galas, A. Aumelas, J. Martinez, 1987, The Journal of biological chemistry.

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology

L. Buée, N. Sergeant, D. Blum, 2011, Neurobiology of Disease.

Atypical, non-standard functions of the microtubule associated Tau protein

L. Buée, E. Mandelkow, E. Mandelkow, 2017, Acta neuropathologica communications.

Nuclear Tau, a Key Player in Neuronal DNA Protection*

L. Buée, N. Sergeant, F. Nesslany, 2010, The Journal of Biological Chemistry.

Synthesis and biological activities of some cholecystokinin analogues substituted in position 29 by a β-alanine

Jean Martinez, M. Galas, A. Aumelas, 2009 .

Synthesis and biological activities of cholecystokinin analogues substituted in position 30 by 3-(1-naphthyl)-l-alanine [Nal(1)] or 3-(2-naphthyl)-l-alanine [Nal(2)]

Jean Martinez, M. Galas, A. Aumelas, 1991 .

Synthesis of cyclic analogues of cholecystokinin highly selective for central receptors.

M. Galas, M. Amblard, A. Aumelas, 2009, International journal of peptide and protein research.

2-Phenylethyl ester and 2-phenylethyl amide derivative analogues of the C-terminal hepta- and octapeptide of cholecystokinin.

M. Galas, A. Aumelas, P. Fulcrand, 2009, International journal of peptide and protein research.

Synthesis of S‐adenosyl‐L‐homocysteine and 5′‐methylthioadenosine specifically tritiated at the 5′C position

M. Galas, J. Beaucourt, G. Guillerm, 1986 .

Amyloid Precursor Protein (APP) Metabolites APP Intracellular Fragment (AICD), Aβ42, and Tau in Nuclear Roles*

L. Buée, M. Galas, O. Huber, 2015, The Journal of Biological Chemistry.

Cyclic cholecystokinin analogues that are highly selective for rat and guinea pig central cholecystokinin receptors.

M. Galas, M. Amblard, J. Martinez, 1990, Molecular pharmacology.

Synthesis and biological activity of 2-phenylethyl ester analogues of C-terminal heptapeptide of cholecystokinin modified in Trp 30 region.

M. Galas, A. Aumelas, M. Rolland, 2009, International journal of peptide and protein research.

Synthesis and biological activity of some partially modified retro-inverso analogues of cholecystokinin.

M. Galas, C. Mendre, A. Aumelas, 1989, Journal of medicinal chemistry.

A pseudopeptide that is a potent cholecystokinin agonist in the peripheral system is able to inhibit the dopamine-like effects of cholecystokinin in the striatum.

C. Gueudet, P. Worms, M. Galas, 1988, The Journal of biological chemistry.

On the importance of the peptide bonds in the C-terminal tetrapeptide of gastrin and in the C-terminal heptapeptide of cholecystokinin

Jean Martinez, M. Galas, J. Bali, 1988 .

Pharmacological activity of cholecystokinin analogues modified in the Met28-Gly29 region.

C. Gueudet, P. Worms, M. Galas, 1990, European journal of pharmacology.

Pharmacological studies on CCKB receptors in guinea pig synaptoneurosomes.

M. Galas, J. Martinez, N. Bernad, 1992, European journal of pharmacology.

On the significance of the C-terminal primary amide in cholecystokinin

Jean Martinez, M. Galas, M. Rolland, 1993 .

AUTORADIOGRAPHIC LOCALIZATION OF CCK BINDING SITES IN THE HUMAN BRAIN

J. Vanderhaeghen, M. Galas, S. Goldman, 1987 .

Alkalizing Drugs Induce Accumulation of Amyloid Precursor Protein By-products in Luminal Vesicles of Multivesicular Bodies*

A. Delacourte, L. Buée, N. Sergeant, 2007, Journal of Biological Chemistry.

Tau Stabilizes Chromatin Compaction

L. Buée, X. Thuru, H. Drobecq, 2021, Frontiers in Cell and Developmental Biology.

The Adenosine A1 Receptor Agonist Adenosine Amine Congener Exerts a Neuroprotective Effect against the Development of Striatal Lesions and Motor Impairments in the 3-Nitropropionic Acid Model of Neurotoxicity

P. d'Alcantara, S. Schiffmann, D. Blum, 2002, The Journal of Neuroscience.

Minocycline in phenotypic models of Huntington's disease

S. Schiffmann, J. Brotchi, M. Levivier, 2005, Neurobiology of Disease.

Boc-Tyr(SO3H)-Nle-Gly-Trp-Nle-Asp-2-Phenylethyl Ester — JMV180: A Unique CCK Analogue with Different Actions on High- and Low-Affinity CCK Receptors

J. Martínez, M. Galas, P. Fulcrand, 1991 .

Large and prolonged in vivo response of pancreatic secretion to phenylethylamide and phenylethylester derivatives of Boc-[Nle28-Nle31]CCK(26–33) in the rat

C. Rozé, M. Galas, J. Martinez, 1992, Peptides.

Cognition and hippocampal synaptic plasticity in mice with a homozygous tau deletion

R. D'Hooge, L. Buée, D. Balschun, 2014, Neurobiology of Aging.

Striatal and Cortical Neurochemical Changes Induced by Chronic Metabolic Compromise in the 3-Nitropropionic Model of Huntington's Disease

S. Schiffmann, D. Blum, M. Galas, 2002, Neurobiology of Disease.

Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms

S. Schiffmann, D. Blum, E. Brouillet, 2004, Neurobiology of Disease.

Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism: Possible implication for Alzheimer’s disease

L. Buée, T. Voet, V. Deramecourt, 2022, Progress in Neurobiology.

Cyclic AMP-induced desensitization of G-protein-regulated phospholipase C in turkey erythrocyte membranes.

M. Galas, T. Harden, 1996, European journal of pharmacology.

Ectosomes: A New Mechanism for Non-Exosomal Secretion of Tau Protein

L. Buée, M. Colin, A. Loyens, 2014, PloS one.

Biological Evaluation of JMV180 Cholecystokinin Analogs

M. Galas, D. Fourmy, M. Amblard, 1994, Annals of the New York Academy of Sciences.

Neuroprotective effect of zVAD against the neurotoxin 3-nitropropionic acid involves inhibition of calpain

S. Schiffmann, D. Blum, E. Brouillet, 2005, Neuropharmacology.

Pin1 allows for differential Tau dephosphorylation in neuronal cells

A. Delacourte, L. Buée, G. Lippens, 2006, Molecular and Cellular Neuroscience.

Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation.

L. Buée, I. Landrieu, G. Lippens, 2015, Biochemistry.

The peptidyl prolyl cis/trans isomerase Pin1/Ess1 inhibits phosphorylation and toxicity of tau in a yeast model for Alzheimer's disease

J. Winderickx, A. Vos, F. Madeo, 2015 .

Correlation between phospholipid breakdown, intracellular calcium mobilization and enzyme secretion in rat pancreatic acini treated with Boc-[Nle28, Nle31]-CCK-7 and JMV180, two cholecystokinin analogues.

M. Galas, J. Martinez, M. Rodríguez, 1990, Cellular Signalling.

A Dual Role of Adenosine A2A Receptors in 3-Nitropropionic Acid-Induced Striatal Lesions: Implications for the Neuroprotective Potential of A2A Antagonists

S. Schiffmann, C. Ledent, Anne‐Sophie Rolland, 2003, The Journal of Neuroscience.

Synphilin-1 Enhances α-Synuclein Aggregation in Yeast and Contributes to Cellular Stress and Cell Death in a Sir2-Dependent Manner

J. Winderickx, L. Buée, C. Delay, 2010, PloS one.

Tau Monoclonal Antibody Generation Based on Humanized Yeast Models

M. Caldara, J. Winderickx, L. Buée, 2014, The Journal of Biological Chemistry.

Genome-wide identification of genic and intergenic neuronal DNA regions bound by Tau protein under physiological and stress conditions

L. Buée, B. Albaud, B. Lefebvre, 2018, Nucleic acids research.

Feeding High-Fat Diet Accelerates Development of Peripheral and Central Insulin Resistance and Inflammation and Worsens AD-like Pathology in APP/PS1 Mice

M. Galas, V. Vrkoslav, V. Strnadová, 2023, Nutrients.