N. Manfrini

发表

Role of microRNAs in translation regulation and cancer

S. Biffo, S. Oliveto, Marilena Mancino, 2017, World journal of biological chemistry.

Mechanisms and regulation of DNA end resection

N. Manfrini, Maria Pia Longhese, M. Longhese, 2010, The EMBO journal.

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.

R. Müller, S. Gallo, S. Ricciardi, 2018, Cell metabolism.

Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits

M. Degano, S. Ricciardi, S. Biffo, 2020, Cells.

High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of TCR-stimulated CD4+ T cells in both mice and humans.

H. Fuchs, D. Busch, V. Gailus-Durner, 2017, Developmental and comparative immunology.

The MRX Complex Plays Multiple Functions in Resection of Yku- and Rif2-Protected DNA Ends

G. Lucchini, N. Manfrini, M. Longhese, 2010, PloS one.

Processing of Meiotic DNA Double Strand Breaks Requires Cyclin-dependent Kinase and Multiple Nucleases*

G. Lucchini, N. Manfrini, A. Citterio, 2010, The Journal of Biological Chemistry.

RACK1 Specifically Regulates Translation through Its Binding to Ribosomes

S. Gallo, S. Ricciardi, S. Biffo, 2018, Molecular and Cellular Biology.

Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study

S. Ricciardi, S. Biffo, S. Oliveto, 2022, International journal of molecular sciences.

Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2

R. De Francesco, S. Ricciardi, S. Biffo, 2022, eBioMedicine.

Maintenance of genome integrity in gametes: coping with accidental and programmed DNA double-strand breaks during meiosis

N. Manfrini, 2011 .

Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response

R. De Francesco, S. Biffo, F. Blasi, 2022, Frontiers in Immunology.

Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae

F. d’Adda di Fagagna, A. Morillon, M. Wery, 2015, eLife.

DNA double-strand breaks in meiosis: checking their formation, processing and repair.

N. Manfrini, I. Guerini, M. Longhese, 2009, DNA repair.

Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma

S. Biffo, S. Oliveto, N. Manfrini, 2021, Nature Communications.

Ribosome profiling unveils translational regulation of metabolic enzymes in primary CD4+ Th1 cells.

S. Biffo, N. Manfrini, R. Alfieri, 2020, Developmental and comparative immunology.

Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation

H. Fuchs, D. Busch, M. D. de Angelis, 2017, Data in brief.

Translational control by mTOR-independent routes: how eIF6 organizes metabolism.

S. Biffo, S. Oliveto, N. Manfrini, 2016, Biochemical Society transactions.

Working hard at the nexus between cell signaling and the ribosomal machinery: An insight into the roles of RACK1 in translational regulation

S. Gallo, N. Manfrini, 2015, Translation.

Crosstalks between translation and metabolism in cancer.

S. Biffo, N. Manfrini, Sara Ricciardi, 2018, Current opinion in genetics & development.

Ribosomal RACK1 promotes proliferation of neuroblastoma cells independently of global translation upregulation.

L. Zolla, N. Manfrini, N. Romano, 2019, Cellular signalling.

RNA‐processing proteins regulate Mec1/ATR activation by promoting generation of RPA‐coated ssDNA

F. d’Adda di Fagagna, A. Morillon, M. Wery, 2015, EMBO reports.

Regulation of the DNA damage response by cyclin-dependent kinases.

N. Manfrini, M. Longhese, M. Falcettoni, 2013, Journal of molecular biology.

Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesis.

S. Minucci, S. Biffo, A. Bachi, 2021, Developmental cell.

Role of the Saccharomyces cerevisiae Rad53 Checkpoint Kinase in Signaling Double-Strand Breaks during the Meiotic Cell Cycle

G. Lucchini, N. Manfrini, I. Guerini, 2008, Molecular and Cellular Biology.

FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy

G. Tonon, M. Sassoè-Pognetto, T. Bonaldi, 2020, Cancer Research.

G1/S and G2/M Cyclin-Dependent Kinase Activities Commit Cells to Death in the Absence of the S-Phase Checkpoint

G. Lucchini, N. Manfrini, M. Longhese, 2012, Molecular and Cellular Biology.

FAM46C Is an Interferon-Stimulated Gene That Inhibits Lentiviral Particle Production by Modulating Autophagy

S. Biffo, A. Cuomo, E. Vicenzi, 2023, Microbiology spectrum.

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.

R. Müller, S. Gallo, S. Biffo, 2018, Cell metabolism.

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling

R. Müller, S. Gallo, S. Biffo, 2018, Cell metabolism.

G1/S and G2/M Cyclin-Dependent Kinase Activities Commit Cells to Death in the Absence of the S-Phase Checkpoint

G. Lucchini, N. Manfrini, E. Gobbini, 2012, Molecular and Cellular Biology.

Ribosome profiling unveils translational regulation of metabolic enzymes in primary CD4+ Th1 cells.

S. Biffo, N. Manfrini, R. Alfieri, 2020, Developmental and comparative immunology.