J. Sandoval

M. Esteller, D. Beer, L. Rozek, 2014, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

ZNF577 Methylation Levels in Leukocytes From Women With Breast Cancer Is Modulated by Adiposity, Menopausal State, and the Mediterranean Diet

F. Casanueva, A. Crujeiras, M. Carreira, 2020, Frontiers in Endocrinology.

In vivo GSH depletion induces c-myc expression by modulation of chromatin protein complexes.

J. Viña, J. Sandoval, José L. Rodríguez, 2009, Free radical biology & medicine.

Glutamate cysteine ligase up-regulation fails in necrotizing pancreatitis.

J. Sastre, F. Pallardó, J. Viña, 2008, Free radical biology & medicine.

Epigenetic crosstalk: a molecular language in human metabolic disorders.

C. Martinez-Jimenez, J. Sandoval, 2015, Frontiers in bioscience.

Id2 leaves the chromatin of the E2F4-p130-controlled c-myc promoter during hepatocyte priming for liver regeneration.

M. Avila, J. Sastre, J. Viña, 2006, Biochemical Journal.

Epigenomic signature of adrenoleukodystrophy predicts compromised oligodendrocyte differentiation

M. Esteller, J. Sandoval, A. Schlüter, 2018, Brain pathology.

CD137 (4-1BB) Costimulation Modifies DNA Methylation in CD8+ T Cell–Relevant Genes

M. Esteller, I. Melero, A. Korman, 2017, Cancer Immunology Research.

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

T. Ørntoft, C. Andersen, M. Esteller, 2014, Nature Communications.

Potential usefulness of pentoxifylline, a non-specific phosphodiesterase inhibitor with anti-inflammatory, anti-thrombotic, antioxidant, and anti-fibrogenic properties, in the treatment of SARS-CoV-2.

J. Sandoval, H. González-Pacheco, L. Amezcua-Guerra, 2020, European review for medical and pharmacological sciences.

Whole genome grey and white matter DNA methylation profiles in dorsolateral prefrontal cortex

M. Esteller, H. Heyn, S. Moran, 2017, Synapse.

Events at the transition between cell cycle exit and oligodendrocyte progenitor differentiation: the role of HDAC and YY1.

J. Sandoval, P. Casaccia‐Bonnefil, Ye He, 2007, Neuron glia biology.

Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice

A. Gutiérrez-Adán, J. Cervera, J. Sandoval, 2022, Leukemia.

Translation of a tissue epigenetic signature to circulating free DNA suggests BCAT1 as a potential noninvasive diagnostic biomarker for lung cancer

J. Galbis-Caravajal, M. Benet, D. Hervás, 2022, Clinical Epigenetics.

MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression

M. Esteller, B. Espinet, J. Sandoval, 2016, Molecular Cancer.

Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice

A. Gutiérrez-Adán, J. Cervera, J. Sandoval, 2022, Leukemia.

Protein phosphatases and chromatin modifying complexes in the inflammatory cascade in acute pancreatitis.

J. Sastre, A. Arduini, J. Sandoval, 2010, World journal of gastrointestinal pharmacology and therapeutics.

Interaction between cytokines and oxidative stress in acute pancreatitis.

J. Sastre, J. Viña, J. Sandoval, 2006, Current medicinal chemistry.

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

M. Esteller, H. Heyn, J. Serra-Musach, 2011, Epigenetics.

The Oxygen Load Supplied during Delivery Room Stabilization of Preterm Infants Modifies the DNA Methylation Profile

D. Hervás, J. Sandoval, A. Parra-Llorca, 2018, The Journal of pediatrics.

Translating cancer epigenomics into the clinic: focus on lung cancer

A. Crujeiras, J. Sandoval, A. Calvo, 2017, Translational research : the journal of laboratory and clinical medicine.

Generation and Characterization of Rat and Mouse Monoclonal Antibodies Specific for MeCP2 and Their Use in X-Inactivation Studies

M. Esteller, E. Kremmer, H. Leonhardt, 2011, PloS one.

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

R. Franklin, J. Sandoval, P. Casaccia‐Bonnefil, 2008, Nature Neuroscience.

DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

T. Spector, J. Bell, K. Ward, 2012, Carcinogenesis.

Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model

M. Esteller, S. Sayols, J. Sandoval, 2013, RNA biology.

Epigenetics and Oxidative Stress in Aging

A. Guillaumet-Adkins, J. Sandoval, Y. Yáñez, 2017, Oxidative medicine and cellular longevity.

Genome-Wide DNA Methylation Analysis Identifies Novel Hypomethylated Non-Pericentromeric Genes with Potential Clinical Implications in ICF Syndrome

M. Esteller, A. Crujeiras, M. Gagliardi, 2015, PloS one.

Novel Insights into DNA Methylation Features in Spermatozoa: Stability and Peculiarities

Holger Heyn, Juan Sandoval, Sergi Sayols, 2012, PloS one.

Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoids

Aurélie A G Gabriel, N. Le Stang, N. Girard, 2019, Nature Communications.

MicroRNA Deregulation in Lung Cancer and Their Use as Clinical Tools

J. Sandoval, P. Lopez-Serra, Paula Lopez-Serra, 2016 .

miRNAs Regulation and Its Role as Biomarkers in Endometriosis

Juan Sandoval, J. Gilabert-Estellés, A. Braza-Boïls, 2016, International journal of molecular sciences.

Epigenetic Regulation of microRNAs in Cancer: Shortening the Distance from Bench to Bedside

E. Bandrés, M. Pajares, J. Sandoval, 2021, International journal of molecular sciences.

Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion

Maite Huarte, C. Kanduri, Ivan Raimondi, 2020, The Journal of cell biology.

Oxidative Stress in the Pathogenesis of Crohn’s Disease and the Interconnection with Immunological Response, Microbiota, External Environmental Factors, and Epigenetics

I. Moret, J. Sandoval, B. Mateos, 2021, Antioxidants.

DNA Methylation Biomarkers in Lung Cancer

J. Sandoval, P. Serra, 2016 .

Epigenetic biomarkers in laboratory diagnostics: emerging approaches and opportunities

F. Pallardó, J. Sandoval, J. García-Giménez, 2013, Expert review of molecular diagnostics.

Molecular-Subtype-Specific Biomarkers Improve Prediction of Prognosis in Colorectal Cancer.

Søren Vang, Juan Sandoval, Halit Ongen, 2017, Cell reports.

An integrated approach to design novel therapeutic interventions for demyelinating disorders

R. Nowakowski, J. Sandoval, P. Casaccia, 2012, The European journal of neuroscience.

Identification of HERC5 and its potential role in NSCLC progression

M. Esteller, A. Risch, M. Westphal, 2015, International journal of cancer.

Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer

F. Setién, M. Esteller, H. Heyn, 2016, Proceedings of the National Academy of Sciences.

Epigenetic control of influenza virus: role of H3K79 methylation in interferon-induced antiviral response

M. Esteller, L. Marcos-Villar, J. Sandoval, 2018, Scientific Reports.

DNA methylation contributes to natural human variation

T. Marquès-Bonet, Liewei Wang, M. Esteller, 2013, Genome research.

DNA methylation contributes to natural human variation Material Supplemental

T. Marquès-Bonet, Liewei Wang, M. Esteller, 2013 .

Whole-genome bisulfite DNA sequencing of a DNMT3B mutant patient

M. Esteller, J. Dopazo, I. Medina, 2012, Epigenetics.

A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients

M. Esteller, A. Lluch, A. Crujeiras, 2019, Clinical Epigenetics.

A prognostic DNA methylation signature for stage I non-small-cell lung cancer.

M. Esteller, D. Beer, Guoan Chen, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Non‐CpG island promoter hypomethylation and miR‐149 regulate the expression of SRPX2 in colorectal cancer

T. Ørntoft, E. Dermitzakis, C. Andersen, 2013, International journal of cancer.

Genome-wide DNA methylation profiling predicts relapse in childhood B-cell acute lymphoblastic leukaemia

M. Esteller, H. Heyn, S. Moran, 2012, British journal of haematology.

Obesity and menopause modify the epigenomic profile of breast cancer.

M. Esteller, J. Jónasson, S. Moran, 2017, Endocrine-related cancer.

Label-free DNA-methylation detection by direct ds-DNA fragment screening using poly-purine hairpins.

L. Lechuga, M. Esteller, R. Eritja, 2018, Biosensors & bioelectronics.

Epigenomic Biomarkers for the Advance of Personalized Medicine

J. Sandoval, J. Méndez-González, 2015 .

Cancer Epigenetic Biomarkers in Liquid Biopsy for High Incidence Malignancies

J. Sandoval, A. Calvo, L. Montuenga, 2021, Cancers.

Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels

R. Siebert, M. Esteller, F. Prósper, 2014, Journal of Hematology & Oncology.

Identification of an episignature of human colorectal cancer associated with obesity by genome-wide DNA methylation analysis

M. Esteller, S. Moran, F. Casanueva, 2018, International Journal of Obesity.

Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: a key role for protein phosphatases.

Juan Sandoval, Javier Escobar, J. Sastre, 2009, Current pharmaceutical design.

Oxidative and nitrosative stress in acute pancreatitis. Modulation by pentoxifylline and oxypurinol.

L. Joosten, J. Sastre, A. Arduini, 2012, Biochemical pharmacology.

Role of redox signaling, protein phosphatases and histone acetylation in the inflammatory cascade in acute pancreatitis. Therapeutic implications.

J. Sastre, A. Arduini, J. Sandoval, 2010, Inflammation & allergy drug targets.

Pentoxifylline Prevents Loss of PP2A Phosphatase Activity and Recruitment of Histone Acetyltransferases to Proinflammatory Genes in Acute Pancreatitis

J. Sastre, J. Sandoval, José L. Rodríguez, 2009, Journal of Pharmacology and Experimental Therapeutics.

Ordered transcriptional factor recruitment and epigenetic regulation of tnf-α in necrotizing acute pancreatitis

L. Joosten, J. Sastre, J. Rodriguez, 2010, Cellular and Molecular Life Sciences.

Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1

R. López-López, M. Pajares, D. Hervás, 2019, Scientific Reports.

The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus

M. Esteller, A. Guillaumet-Adkins, L. Montoliu, 2014, Epigenetics & Chromatin.

Methods for analysis of specific DNA methylation status.

R. Urtasun, M. Pajares, J. Sandoval, 2020, Methods.

MicroRNA expression profiling and DNA methylation signature for deregulated microRNA in cutaneous T-cell lymphoma.

F. Climent, M. Esteller, P. Ortiz-Romero, 2015, The Journal of investigative dermatology.

Primary cutaneous marginal zone B-cell lymphoma: Response to treatment and disease-free survival in a series of 137 patients

F. Climent, J. Rodríguez-Peralto, P. Ortiz-Romero, 2013 .

Early radiological response as predictor of overall survival in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor mutations.

J. Sandoval, A. Lahoz, D. Lorente, 2018, Journal of thoracic disease.

The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus

M. Esteller, A. Guillaumet-Adkins, L. Montoliu, 2014, Epigenetics & Chromatin.

RNAPol-ChIP: a novel application of chromatin immunoprecipitation to the analysis of real-time gene transcription.

J. Sastre, J. Sandoval, José L. Rodríguez, 2004, Nucleic acids research.

Inhibition of p53 Transcriptional Activity: A Potential Target for Future Development of Therapeutic Strategies for Primary Demyelination

Jin Young Kim, J. Sandoval, P. Casaccia‐Bonnefil, 2008, The Journal of Neuroscience.

Molecular mechanisms of Id2 down-regulation in rat liver after acetaminophen overdose. Protection by N-acetyl-L-cysteine

J. Viña, J. Sandoval, E. R. García-Trevijano, 2010, Free radical research.

Maternal imprinting on cognition markers of wild type and transgenic Alzheimer’s disease model mice

R. Franco, J. Sandoval, F. Gil-Bea, 2018, Scientific Reports.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

Epigenetic Silencing of Tumor Suppressor miR-124 Directly Supports STAT3 Activation in Cutaneous T-Cell Lymphoma

L. Espinosa, A. Bigas, J. Sandoval, 2020, Cells.

Epigenetic Regulation of Early- and Late-Response Genes in Acute Pancreatitis

J. Sastre, J. Sandoval, José L. Rodríguez, 2016, The Journal of Immunology.

NF-ĸB as Node for Signal Amplification During Weaning

J. Viña, A. Bosch, J. Sandoval, 2011, Cellular Physiology and Biochemistry.

Vitamin E deficiency induces liver nuclear factor-κB DNA-binding activity and changes in related genes

F. Pallardó, T. Barber, J. Viña, 2005, Free radical research.

MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression

M. Esteller, B. Espinet, J. Sandoval, 2016, Molecular Cancer.

Corrigendum: A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

T. Ørntoft, C. Andersen, M. Esteller, 2016, Nature Communications.

DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients

S. Navas-Carretero, F. Milagro, J. Martínez, 2017, Scientific Reports.

Identification of Epigenetic Methylation Signatures With Clinical Value in Crohn's Disease

D. Hervás, J. Sandoval, M. Iborra, 2019, Clinical and translational gastroenterology.

Disruption of NIPBL/Scc2 in Cornelia de Lange Syndrome provokes cohesin genome-wide redistribution with an impact in the transcriptome

M. Esteller, A. Cuadrado, B. Puisac, 2021, Nature communications.

A Novel Epigenetic Signature for Early Diagnosis in Lung Cancer

Antoni Rosell, Juan Sandoval, Luis M. Montuenga, 2016, Clinical Cancer Research.

Epigenetic alterations leading to TMPRSS4 promoter hypomethylation and protein overexpression predict poor prognosis in squamous lung cancer patients

M. Esteller, M. Pajares, J. Sandoval, 2016, Oncotarget.

Epigenetic Modifiers Are Necessary but Not Sufficient for Reprogramming Non-Myelinating Cells into Myelin Gene-Expressing Cells

J. Sandoval, P. Casaccia, L. Cai, 2010, PloS one.

Genome-wide DNA methylation pattern in visceral adipose tissue differentiates insulin-resistant from insulin-sensitive obese subjects.

M. Esteller, J. Moreno-Navarrete, W. Ricart, 2016, Translational research : the journal of laboratory and clinical medicine.

Identification of a gene-pathway associated with non-alcoholic steatohepatitis.

José L Sevilla, Shelly C. Lu, Á. Rubio, 2007, Journal of hepatology.

An Epigenetic Signature in Adipose Tissue Is Linked to Nicotinamide N‐Methyltransferase Gene Expression

M. Esteller, J. Moreno-Navarrete, W. Ricart, 2018, Molecular nutrition & food research.

A two-gene epigenetic signature for the prediction of response to neoadjuvant chemotherapy in triple-negative breast cancer patients

M. Esteller, A. Lluch, A. Crujeiras, 2019, Clinical Epigenetics.

Epigenetics of Inflammatory Bowel Disease: Unraveling Pathogenic Events

I. Moret, J. Sandoval, B. Mateos, 2019, Crohn's & Colitis 360.

Identification of Epigenetic Methylation Signatures With Clinical Value in Crohn's Disease.

D. Hervás, J. Sandoval, M. Iborra, 2019, Clinical and translational gastroenterology.

MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

E. Dermitzakis, C. Andersen, M. Esteller, 2020, Nature Communications.

Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1.

R. López-López, M. Pajares, D. Hervás, 2019 .