E. Wang

发表

The HDAC3–SMARCA4–miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma

Noah E. Berlow, Matthew N. Svalina, T. Perkins, 2018, Science Signaling.

Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains

J. Kinney, Junwei Shi, C. Vakoc, 2015, Nature Biotechnology.

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

S. Lowe, J. Qi, J. Bradner, 2011, Nature.

Up‐regulated P21CIP1 expression is part of the regulation quantitatively controlling serum deprivation‐induced apoptosis

E. Wang, A. Duttaroy, E. Wang, 1997, Journal of cellular biochemistry.

RNA Splicing and Cancer.

I. Aifantis, E. Wang, 2020, Trends in cancer.

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

Michael A. Freitas, Miranda L. Gardner, C. Bloomfield, 2019, Nature Communications.

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

J. Zuber, S. Minucci, R. Johnstone, 2015, Blood.

SMARCA4 biology in alveolar rhabdomyosarcoma

Kenneth Chang, J. Michalek, A. Karnezis, 2022, Oncogene.

The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;NrasG12D acute myeloid leukemia

S. Lowe, J. Zuber, Junwei Shi, 2013, Oncogene.

Targeting the Noncoding Genome: Superenhancers Meet Their Kryptonite.

E. Wang, Ioannis D. Aifantis, 2017, Cancer discovery.

NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia

J. Brumbaugh, K. Hochedlinger, O. Abdel-Wahab, 2022, Nature Immunology.

Small-Molecule Inhibition of BRD4 Is a Novel Promising Approach to Therapeutically Target Leukemia Stem Cells in AML,

S. Lowe, J. Bradner, J. Zuber, 2011 .

Cell type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening

T. Sakellaropoulos, D. Fenyö, A. Tsirigos, 2022, bioRxiv.

Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia.

Alexander V Penson, O. Abdel-Wahab, R. Bradley, 2022, Cancer cell.

Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation

O. Abdel-Wahab, N. Rosen, F. McCormick, 2022, Cancer discovery.

Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia.

Marc L. Mendillo, Hu Li, A. Heguy, 2020, Cancer discovery.

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.

T. Graeber, S. Lowe, J. Zuber, 2011, Genes & development.

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

Ming Yu, Junwei Shi, Eric Wang, 2013, Genes & development.

JAB1/COPS5 is a putative oncogene that controls critical oncoproteins deregulated in prostate cancer.

Guang Zhou, D. Danielpour, E. Wang, 2019, Biochemical and biophysical research communications.

Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia

R. Roeder, Jun Zhu, S. Kawaoka, 2013, Proceedings of the National Academy of Sciences.

SIRT4 inhibits malignancy progression of NSCLCs, through mitochondrial dynamics mediated by the ERK-Drp1 pathway

E. Wang, J. Xing, Q. Dong, 2017, Oncogene.

The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer

J. Kinney, Yutaka Suzuki, Jae-seok Roe, 2015, eLife.

regulation Myc enhancer-mediated Role of SWI / SNF in acute leukemia maintenance and Material Supplemental

J. Kendall, M. Wigler, R. Young, 2013 .

Valine tRNA levels and availability regulate complex I assembly in leukaemia

A. Tsirigos, A. Kloetgen, I. Aifantis, 2021, Nature.

Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition

O. Abdel-Wahab, F. McCormick, R. Bradley, 2021, Nature Genetics.

Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation.

A. Tsirigos, Xufeng Chen, A. Kloetgen, 2021, Cell stem cell.

A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit.

J. Zuber, M. Chou, G. Blobel, 2009, Molecular cell.

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.

Pedro P. Rocha, L. Zon, D. Reinberg, 2016, Cell stem cell.

Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia.

A. Krainer, O. Abdel-Wahab, Kuan-Ting Lin, 2019, Cancer cell.

The impact of inflammation-induced tumor plasticity during myeloid transformation.

J. Byrd, O. Abdel-Wahab, A. Tsirigos, 2022, Cancer discovery.

Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.

T. Sakellaropoulos, A. Tsirigos, Xufeng Chen, 2019, Cancer discovery.

Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

J. Wolchok, O. Abdel-Wahab, D. Chowell, 2021, Cell.

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.

Yutaka Suzuki, L. Joshua-Tor, D. Pappin, 2015, Molecular cell.

Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening

T. Sakellaropoulos, D. Fenyö, A. Tsirigos, 2023, Nature Biotechnology.

Pharmacologicmodulation of RNA splicing enhances anti-tumor immunity

J. Wolchok, O. Abdel-Wahab, D. Chowell, 2022 .

Kinase Dead BTK Mutations Confer Resistance to Covalent and Noncovalent BTK Inhibitors but Are Susceptible to Clinical Stage BTK Degraders

A. Zelenetz, O. Abdel-Wahab, A. Linley, 2022, Blood.

Preclinical rationale for entinostat in embryonal rhabdomyosarcoma

Noah E. Berlow, Matthew N. Svalina, T. Perkins, 2019, Skeletal Muscle.