I. Struman

发表

Cell communication via microRNA exchange between endothelial and tumour cells during anti-cancer neoadjuvant chemotherapy

Stella Dederen, I. Struman, 2018 .

Exploring the RNA landscape of endothelial exosomes.

I. Struman, Jennifer Pérez-Boza, Michelle Lion, 2018, RNA.

Deeper insights into long-term survival heterogeneity of pancreatic ductal adenocarcinoma (PDAC) patients using integrative individual- and group-level transcriptome network analyses

K. Van Steen, I. Struman, C. Josse, 2020, Scientific Reports.

Evidence for a second receptor binding site on human prolactin.

J. Martial, V. Mainfroid, I. Struman, 1994, The Journal of biological chemistry.

The antiangiogenic factor 16K PRL induces programmed cell death in endothelial cells by caspase activation.

J. Martial, J. Martini, I. Struman, 2000, Molecular endocrinology.

The antiangiogenic factor 16K human prolactin induces caspase-dependent apoptosis by a mechanism that requires activation of nuclear factor-kappaB.

J. Martial, V. Bours, F. Rentier-Delrue, 2003, Molecular endocrinology.

Phenotyping and outcome on contemporary management in a German cohort of patients with peripartum cardiomyopathy

K. Sliwa, D. Tsikas, J. Jordan, 2013, Basic Research in Cardiology.

The Antiangiogenic 16K Prolactin Impairs Functional Tumor Neovascularization by Inhibiting Vessel Maturation

J. Martial, S. Blacher, S. Herkenne, 2011, PloS one.

The antiangiogenic factor 16 K hPRL induces caspases-dependent apoptosis by a mechanism that requires activation of NF-κ

J. Martial, V. Bours, I. Struman, 2009 .

Neoadjuvant Chemotherapy in Breast Cancer Patients Induces miR‐34a and miR‐122 Expression

V. Bours, G. Jerusalem, I. Struman, 2014, Journal of cellular physiology.

MiR-205 is a novel biomarker for hereditary hemorrhagic telangiectasia with antiangiogenic function

I. Struman, C. Bernabéu, L. Botella, 2013 .

MiR-205 is downregulated in hereditary hemorrhagic telangiectasia and impairs TGF-beta signaling pathways in endothelial cells

J. Martial, I. Struman, C. Bernabéu, 2013, Angiogenesis.

Angiogenesis pre print version 1 MiR205 MiR205 MiR205 is a novel biomarker for hereditary hemorrhagic telangiectasia with antiangiogenic function

J. Martial, I. Struman, C. Bernabéu, 2013 .

controlled randomized study is needed in order to determine the true value of bromocriptine as a specific novel therapy for PPCM

H. Drexler, D. Hilfiker-Kleiner, I. Struman, 2007 .

Biomarkers in systemic sclerosis-associated interstitial lung disease: review of the literature

M. Malaise, D. De seny, I. Struman, 2019, Rheumatology.

Molecular targeting of antiangiogenic factor 16K hPRL inhibits oxygen-induced retinopathy in mice.

J. Martial, F. Rentier-Delrue, M. Grant, 2004, Investigative ophthalmology & visual science.

Proteolytic Cleavage Confers Nitric Oxide Synthase Inducing Activity upon Prolactin*

B. Freeman, J. Eiserich, I. Struman, 2000, The Journal of Biological Chemistry.

A peptide mimicking the C‐terminal part of the reactive center loop induces the transition to the latent form of plasminogen activator inhibitor type‐1

J. Martial, S. D'amico, I. Struman, 2012, FEBS letters.

Recovery from postpartum cardiomyopathy in 2 patients by blocking prolactin release with bromocriptine.

H. Drexler, D. Hilfiker-Kleiner, I. Struman, 2007, Journal of the American College of Cardiology.

Sprouty1, a new target of the angiostatic agent 16K prolactin, negatively regulates angiogenesis

J. Martial, I. Struman, C. Sabatel, 2010, Molecular Cancer.

Inhibition of tumor growth and metastasis establishment by adenovirus-mediated gene transfer delivery of the antiangiogenic factor 16K hPRL.

J. Foidart, A. Noël, J. Martial, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Endothelial extracellular vesicles promote tumour growth by tumour‐associated macrophage reprogramming

F. Dequiedt, C. Remacle, S. Rahmouni, 2022, Journal of extracellular vesicles.

16-kDa Prolactin and Bromocriptine in Postpartum Cardiomyopathy

K. Sliwa, D. Hilfiker-Kleiner, I. Struman, 2012, Current Heart Failure Reports.

Inhibition of the mitochondrial protein Opa1 curtails breast cancer growth

L. Scorrano, F. Grespi, M. Giacomello, 2022, Journal of experimental & clinical cancer research : CR.

The interaction of uPAR with VEGFR2 promotes VEGF-induced angiogenesis

P. Carmeliet, J. Martial, S. Herkenne, 2015, Science Signaling.

PAI-1 mediates the antiangiogenic and profibrinolytic effects of 16K prolactin

P. Carmeliet, J. Martial, A. Gils, 2014, Nature Medicine.

hnRNPA2B1 inhibits the exosomal export of miR-503 in endothelial cells

F. Dequiedt, I. Struman, Jennifer Pérez-Boza, 2020, Cellular and Molecular Life Sciences.

Increased KL-6 levels in moderate to severe COVID-19 infection

M. Moutschen, A. Rousseau, E. Cavalier, 2022, PloS one.

N-Hydroxy-6-(5-Nitro- Naphtalimide)-Hexanamide Inhibits Lysine Deacetylation, Mitigates Angiogenesis and Reduces Tumor Growth

A. Noël, P. Delvenne, J. Wouters, 2015 .

Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice

J. Rakic, V. Lambert, J. Foidart, 2013, Nature Protocols.

Cathepsin D processes human prolactin into multiple 16K-like N-terminal fragments: study of their antiangiogenic properties and physiological relevance.

J. Martial, P. Kelly, G. Bolbach, 2004, Molecular endocrinology.

The addition of nine residues at the C-terminus of human prolactin drastically alters its biological properties.

J. Martial, E. Goormaghtigh, I. Struman, 1993, European journal of biochemistry.

Circulating microRNA-based screening tool for breast cancer

P. Geurts, V. Bours, G. Jerusalem, 2015, Oncotarget.

Macrophage-derived exosomes attenuate fibrosis in airway epithelial cells through delivery of antifibrotic miR-142-3p

F. Dequiedt, M. Malaise, I. Struman, 2020, Thorax.

Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer

A. Noël, J. Martial, V. Bours, 2015, Oncotarget.

Vimentin prevents a miR-dependent negative regulation of tissue factor mRNA during epithelial–mesenchymal transitions and facilitates early metastasis

A. Noël, C. Gilles, M. Polette, 2020, Oncogene.

Exosomal miRNAs in Lung Diseases: From Biologic Function to Therapeutic Targets

M. Malaise, I. Struman, J. Guiot, 2019, Journal of clinical medicine.

A Blood Exosomal miRNA Signature in Acute Respiratory Distress Syndrome

M. Malaise, B. Misset, I. Struman, 2021, Frontiers in Molecular Biosciences.

The transcription factor ERG recruits CCR4–NOT to control mRNA decay and mitotic progression

M. Vidal, N. Simonis, F. Dequiedt, 2016, Nature Structural &Molecular Biology.

Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels

F. Dequiedt, I. Struman, M. Njock, 2022, BMC Biology.

Extracellular Vesicles Mediate Communication between Endothelial and Vascular Smooth Muscle Cells

M. Thiry, S. Herkenne, I. Struman, 2021, International journal of molecular sciences.

hnRNPA2B1 inhibits the exosomal export of miR-503 in endothelial cells

F. Dequiedt, I. Struman, Jennifer Pérez-Boza, 2020, Cellular and Molecular Life Sciences.

Dre-miR-2188 Targets Nrp2a and Mediates Proper Intersegmental Vessel Development in Zebrafish Embryos

Gabriela R. Moura, H. Pendeville, I. Struman, 2012, PloS one.

The expression of prolactin and its cathepsin D-mediated cleavage in the bovine corpus luteum vary with the estrous cycle.

J. Martial, F. Gaunitz, C. Isidoro, 2007, American journal of physiology. Endocrinology and metabolism.

uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

K. Alitalo, F. Morfoisse, S. Blacher, 2018, Nature Communications.

Expression of the antiangiogenic factor 16K hPRL in human HCT116 colon cancer cells inhibits tumor growth in Rag1(-/-) mice.

J. Martial, J. Martini, I. Struman, 2001, Cancer research.

Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: activation of plasminogen activator inhibitor 1 expression.

J. Martial, I. Struman, H. Lee, 1998, Endocrinology.

miRNA cargo within exosome‐like vesicle transfer influences metastatic bone colonization

E. Bandrés, F. Lecanda, D. Luis-Ravelo, 2014, Molecular oncology.

The antiangiogenic factor, 16-kDa human prolactin, induces endothelial cell cycle arrest by acting at both the G0-G1 and the G2-M phases.

J. Martial, I. Struman, A. Cornet, 2005, Molecular endocrinology.

159 Neoadjuvant chemotherapy in breast cancer patients induces expression of miR-34a and miR-122

V. Bours, G. Jerusalem, I. Struman, 2014 .

MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy.

K. Sliwa, V. Lambert, J. Martial, 2013, The Journal of clinical investigation.

The angiostatic protein 16K human prolactin significantly prevents tumor-induced lymphangiogenesis by affecting lymphatic endothelial cells.

A. Noël, J. Martial, S. Blacher, 2011, Endocrinology.

A Cathepsin D-Cleaved 16 kDa Form of Prolactin Mediates Postpartum Cardiomyopathy

K. Sliwa, J. Balligand, H. Drexler, 2007, Cell.

MicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells

J. Rakic, V. Lambert, A. Noël, 2011, PloS one.

Exploring the RNA landscape of endothelial exosomes

I. Struman, Jennifer Pérez-Boza, Michelle Lion, 2018, RNA.

Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis.

J. Martial, V. Mainfroid, H. Lee, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin.

J. Martial, I. Struman, R. Weiner, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Prolactin/growth hormone–derived antiangiogenic peptides highlight a potential role of tilted peptides in angiogenesis

R. Brasseur, J. Martial, L. Lins, 2006, Proceedings of the National Academy of Sciences.

Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels

F. Dequiedt, I. Struman, M. Njock, 2022, BMC biology.

Zebrafish Sox7 and Sox18 function together to control arterial-venous identity.

J. Martial, H. Pendeville, V. Pasque, 2008, Developmental biology.

Evaluation of Bromocriptine in the Treatment of Acute Severe Peripartum Cardiomyopathy: A Proof-of-Concept Pilot Study

K. Sliwa, J. McMurray, D. Hilfiker-Kleiner, 2010, Circulation.

NF-κB activation in endothelial cells is critical for the activity of angiostatic agents

J. Martial, A. Griffioen, K. Mayo, 2009, Molecular Cancer Therapeutics.

Stabilization of T7-promoter-based pARHS expression vectors using the parB locus.

J. Martial, I. Struman, L. De Moerlooze, 1992, Gene.

uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis

K. Alitalo, F. Morfoisse, S. Blacher, 2018, Nature Communications.

Matrix metalloproteinase-2 governs lymphatic vessel formation as an interstitial collagenase.

V. Lambert, P. Carmeliet, J. Foidart, 2012, Blood.

Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization

V. Lambert, A. Noël, S. Heymans, 2021, Aging.

The angiostatic 16K human prolactin overcomes endothelial cell anergy and promotes leukocyte infiltration via nuclear factor-kappaB activation.

J. Martial, A. Griffioen, I. Struman, 2007, Molecular endocrinology.

The angiostatic 16 K human prolactin overcomes endothelial cell anergy and promotes leukocyte infiltration via NF-κ B activation

J. Martial, A. Griffioen, I. Struman, 2009 .

Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes

D. Baiwir, E. De Pauw, A. Blomme, 2016, Oncotarget.

The 14-Kilodalton Human Growth Hormone Fragment a Potent Inhibitor of Angiogenesis and Tumor Metastasis

M. Rahmani, I. Struman, K. Bajou, 2023, International journal of molecular sciences.

Antiangiogenic liposomal gene therapy with 16K human prolactin efficiently reduces tumor growth.

A. Noël, J. Martial, S. Blacher, 2009, Cancer letters.

Inhibition of tumor growth and metastasis establishment by adenovirus-mediated gene transfer delivery of the antiangiogenic factor 16K hPRL.

Jean-Michel Foidart, J. Foidart, A. Noël, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Systematic review of overlapping microRNA patterns in COVID-19 and idiopathic pulmonary fibrosis

M. Malaise, C. Remacle, I. Struman, 2023, Respiratory Research.

Sputum exosomes: promising biomarkers for idiopathic pulmonary fibrosis

F. Dequiedt, M. Thiry, I. Struman, 2018, Thorax.

Altered epigenetic features in circulating nucleosomes in idiopathic pulmonary fibrosis

I. Struman, J. Guiot, M. Henket, 2017, Clinical Epigenetics.

Altered epigenetic features in circulating nucleosomes in idiopathic pulmonary fibrosis

I. Struman, J. Guiot, M. Henket, 2017, Clinical Epigenetics.

Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice

J. Rakic, V. Lambert, J. Foidart, 2013, Nature Protocols.

Neoadjuvant Chemotherapy in Breast Cancer Patients Induces miR-34a and miR-122 Expression

V. Bours, G. Jerusalem, I. Struman, 2014 .

Zebrafish Sox7 and Sox18 function together to control arterial-venous identity.

J. Martial, V. Pasque, B. Peers, 2008, Developmental biology.

Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer

A. Noël, J. Martial, V. Bours, 2015, Oncotarget.

Cardiomyopathy : A Proof-of-Concept Pilot Study Evaluation of Bromocriptine in the Treatment of Acute Severe Peripartum

K. Sliwa, J. McMurray, D. Hilfiker-Kleiner, 2010 .