J. Hopkins

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Expression of Ovine Herpesvirus -2 Encoded MicroRNAs in an Immortalised Bovine – Cell Line

K. Nightingale, Claire S. Levy, J. Hopkins, 2014, PloS one.

Differential cytokine gene expression profiles in the three pathological forms of sheep paratuberculosis

J. Hopkins, J. Smeed, C. Watkins, 2007, BMC veterinary research.

Generation of a sheep x mouse heterohybridoma cell line (1C6.3a6T.1D7) and evaluation of its use in the production of ovine monoclonal antibodies.

J. N. Flynn, J. Hopkins, G. Harkiss, 1989, Journal of immunological methods.

Variations in IL-23 and IL-25 receptor gene structure, sequence and expression associated with the two disease forms of sheep paratuberculosis

F. Chianini, J. Hopkins, R. Dalziel, 2016, Veterinary Research.

The Effect of Gene Gun‐delivered pGM‐CSF on the Immunopathology of the Vaccinated Skin

J. Hopkins, R. Dalziel, S. Rhind, 2007, Scandinavian journal of immunology.

Enhanced proliferation of CD4+ T cells induced by dendritic cells following antigen uptake in the presence of specific antibody.

J. Hopkins, G. Harkiss, S. Coughlan, 1996, Veterinary immunology and immunopathology.

The sheepCD1 gene family contains at least fourCD1B homologues

B. Dutia, J. Hopkins, E. Ferguson, 2007, Immunogenetics.

The sheep CD1 gene family contains at least four CD1B homologues

B. Dutia, J. Hopkins, E. Ferguson, 1996, Immunogenetics.

Patterns of major histocompatibility complex class II expression by T cell subsets in different immunological compartments. 2. Altered expression and cell function following activation in vivo

B. Dutia, J. Hopkins, R. Dalziel, 1993, European journal of immunology.

Interleukin‐1 receptor expression by ovine afferent lymph dendritic cells: response to secondary antigen challenge

J. Hopkins, D. Sargan, C. Fiskerstrand, 1994, European journal of immunology.

Biochemical and phenotypic characterization of the ovine beta 2 (leucocyte) integrins.

V. Gupta, J. Hopkins, R. Dalziel, 1995, Journal of comparative pathology.

Sheep CD1 genes and proteins.

B. Dutia, J. Hopkins, S. Rhind, 2000, Veterinary immunology and immunopathology.

Amino-terminal sequencing of sheep CD1 antigens and identification of a sheep CD1D gene

B. Dutia, J. Hopkins, S. Rhind, 1999, Immunogenetics.

Analysis of the CD1 cluster in sheep.

B. Dutia, J. Hopkins, 1991, Veterinary immunology and immunopathology.

Use of DNA fingerprinting in paternity analysis of closely-related Exmoor ponies.

J. Hopkins, B. Hopkins, F. O'Connell, 1991, Equine veterinary journal.

The effects of gene gun delivered pIL-3 adjuvant on skin pathology and cytokine expression.

J. Hopkins, R. Dalziel, S. Rhind, 2007, Veterinary immunology and immunopathology.

Follicular Dendritic Cell-Specific Prion Protein (PrPc) Expression Alone Is Sufficient to Sustain Prion Infection in the Spleen

K. Rajewsky, K. Brown, N. Mabbott, 2011, PLoS pathogens.

Summary of the third European Veterinary Immunology Workshop (EVIW), September 2009, Berlin, Germany.

C. Fossum, W. Ollier, D. Werling, 2010, Veterinary immunology and immunopathology.

Evidence for the expression of two distinct MHC class II DR beta like molecules in the sheep.

B. Dutia, J. Hopkins, K. Ballingall, 2009, Animal genetics.

Identification of a putative cellular receptor for the lentivirus visna virus.

B. Dutia, J. Hopkins, R. Dalziel, 1991, The Journal of general virology.

In vivo modulation of CD1 and MHC class II expression by sheep afferent lymph dendritic cells. Comparison of primary and secondary immune responses

B. Dutia, J. Hopkins, R. Bujdoso, 1989, The Journal of experimental medicine.

Expression and characterization of ovine major histocompatibility complex class II (OLA-DR) genes.

D. Haig, B. Dutia, J. Hopkins, 2009, Animal Genetics.

Elevated manganese levels in blood and central nervous system occur before onset of clinical signs in scrapie and bovine spongiform encephalopathy.

J. Hopkins, D. Brown, J. Sassoon, 2007, Journal of animal science.

Human platelet glycoprotein VI function is antagonized by monoclonal antibody‐derived Fab fragments

L. A. Feeney, J. Villeval, C. Gachet, 2003, Journal of thrombosis and haemostasis : JTH.

BoLA class I charge heterogeneity reflects the expression of more than two loci.

J. Hopkins, E. Glass, S. Al-Murrani, 2009, Animal genetics.

Scrapie infection and endogenous retroviral expression in sheep lymphoid tissues.

N. Hunter, J. Hopkins, F. Houston, 2021, Veterinary immunology and immunopathology.

Differential expression of erythroid genes in prion disease.

J. Fazakerley, J. Hopkins, G. Miele, 2007, Biochemical and biophysical research communications.

Edinburgh Quantifying the Survival of Multiple Salmonella enterica Serovars in vivo using Massively-parallel Whole Genome Sequencing to Predict Zoonotic Risk

J. Hopkins, M. Bugarel, F. Turner, 2018 .

Nature and consequences of interactions between Salmonella enterica serovar Dublin and host cells in cattle

M. Stevens, C. Vrettou, J. Hopkins, 2019, Veterinary Research.

Differential expression of ovine CD1

J. Hopkins, S. Rhind, E. S. Grant, 2000, Immunology.

A study on lymphocyte activation in maedi-visna virus induced pneumonia.

D. Collie, J. Hopkins, H. Miller, 1995, Veterinary immunology and immunopathology.

Immune cell populations in the equine corpus luteum throughout the oestrous cycle and early pregnancy: an immunohistochemical and flow cytometric study.

J. Hopkins, D. Lawler, E. Watson, 1999, Journal of reproduction and fertility.

Edinburgh Research Explorer Relationship between susceptibility of Blackface sheep to Teladorsagia circumcincta infection and an inflammatory mucosal T cell response

D. Shaw, J. Pemberton, J. Hopkins, 2017 .

Variations in T Cell Transcription Factor Sequence and Expression Associated with Resistance to the Sheep Nematode Teladorsagia circumcincta

J. Hopkins, S. Bishop, A. Gossner, 2016, PloS one.

Reporter gene expression in dendritic cells after gene gun administration of plasmid DNA.

J. Hopkins, C. Watkins, G. Harkiss, 2005, Vaccine.

Analysis of reporter gene expression in ovine dermis and afferent lymph dendritic cells in vitro and in vivo.

J. Hopkins, C. Watkins, G. Harkiss, 1999, Veterinary immunology and immunopathology.

Persistent expression of Ia antigen and viral genome in visna-maedi virus-induced inflammatory cells. Possible role of lentivirus-induced interferon

H. Gendelman, J. Clements, O. Narayan, 1985, The Journal of experimental medicine.

T cell activation by Theileria annulata‐infected macrophages correlates with cytokine production

J. Hopkins, D. Brown, E. Glass, 1995, Clinical and experimental immunology.

T cell activation byTheileria annulata-infected macrophages correlates withcytokine production

J. Hopkins, E. Glass, G. Russell, 1995 .

Edinburgh Research Explorer Exploring the abomasal lymph node transcriptome for genes associated with resistance to the sheep nematode Teladorsagia

J. Hopkins, Anagha A. Joshi, H. Wilkie, 2017 .

Analysis of the expression and secretion of isotypes of sheep B cell immunoglobulins with a panel of isotype-specific monoclonal antibodies.

D. Allen, J. Hopkins, I. Mcconnell, 1995, Research in veterinary science.

Identification of three myeloid-specific differentiation antigens in sheep.

V. Gupta, J. Hopkins, 1996, Veterinary immunology and immunopathology.

Identification of CD45 (leucocyte common antigen) in the domestic cat.

R. Else, J. Hopkins, I. Mcconnell, 1995, Research in veterinary science.

Comparison of workshop CD45R monoclonal antibodies with OvCD45R monoclonal antibodies in sheep.

B. Dutia, J. Hopkins, A. Ross, 1993, Veterinary immunology and immunopathology.

Analysis of the monoclonal antibodies comprising WC6.

B. Dutia, J. Hopkins, A. Ross, 1993, Veterinary immunology and immunopathology.

Early events in immune evasion by the lentivirus maedi-visna occurring within infected lymphoid tissue

D. Allen, H. Reyburn, J. Hopkins, 1993, Journal of virology.

Discrimination between major histocompatibility complex class II DQ and DR locus products in cattle.

B. Dutia, J. Hopkins, E. Glass, 2009, Animal genetics.

Discrimination of two subsets of CD1 molecules in the sheep.

B. Dutia, J. Hopkins, S. Rhind, 1996, Veterinary immunology and immunopathology.

Sequence of the sheep interleukin-10-encoding cDNA.

B. Dutia, J. Hopkins, R. Dalziel, 1994, Gene.

Studies on the lymphocytes of sheep. Destination of lymph‐borne immunoblasts in relation to their tissue of origin

J. Hopkins, E. Orlans, J. Hall, 1977, European journal of immunology.

Fcγ Receptor Expression on Sheep Afferent Lymph Dendritic Cells and Rapid Modulation of Cell Surface Phenotype Following Fcγ Receptor Engagement In Vitro and In Vivo

J. Hopkins, G. Harkiss, L. Dickson, 1996, Scandinavian journal of immunology.

Uptake of antigen by afferent lymph dendritic cells mediated by antibody

J. Hopkins, I. Mcconnell, G. Harkiss, 1990, European journal of immunology.

Exploring the abomasal lymph node transcriptome for genes associated with resistance to the sheep nematode Teladorsagia circumcincta

A. Joshi, J. Hopkins, A. Gossner, 2013, Veterinary Research.

Relationship between susceptibility of Blackface sheep to Teladorsagia circumcincta infection and an inflammatory mucosal T cell response

D. Shaw, J. Pemberton, J. Hopkins, 2012, Veterinary Research.

Phenotypic analysis of host-parasite interactions in lambs infected with Teladorsagia circumcincta.

J. Pemberton, D. Beraldi, J. Hopkins, 2008, International journal for parasitology.

Characterization of sheep afferent lymph dendritic cells and their role in antigen carriage

B. Dutia, J. Hopkins, R. Bujdoso, 1989, The Journal of experimental medicine.

Skin‐derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure

N. Mabbott, J. Hopkins, Joanne Mohan, 2005, Immunology.

A novel expression vector for transfection of bovine MHC class I genes.

J. Hopkins, G. Russell, R. Spooner, 1996, Gene.

Immunological aspects of lymphocyte recirculation.

J. Hopkins, I. Mcconnell, I. McConnell, 1984, Veterinary immunology and immunopathology.

Quantifying the Survival of Multiple Salmonella enterica Serovars In Vivo via Massively Parallel Whole-Genome Sequencing To Predict Zoonotic Risk

M. Stevens, J. Hopkins, M. Bugarel, 2017, Applied and Environmental Microbiology.

Retrospective application of transposon-directed insertion-site sequencing to investigate niche-specific virulence of Salmonella Typhimurium in cattle

N. Thomson, R. Chaudhuri, M. Stevens, 2019, BMC Genomics.

Lymphocyte subpopulations in the blood of sheep persistently infected with border disease virus.

M. Brandon, H. Reid, P. Nettleton, 1989, Clinical and experimental immunology.

Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants.

J. Hopkins, W. Davis, J. Naessens, 1993, Veterinary immunology and immunopathology.

Initial lentivirus-host interactions within lymph nodes: a study of maedi-visna virus infection in sheep

D. Allen, I. Maclennan, J. Hopkins, 1995, Journal of virology.

Reactivity of the CD11/CD18 workshop monoclonal antibodies in the sheep.

V. Gupta, J. Hopkins, I. Mcconnell, 1993, Veterinary immunology and immunopathology.

Characterization of monoclonal antibodies specific for alpha- and beta-chains of sheep MHC class II.

B. Dutia, J. Hopkins, R. Bujdoso, 1990, Immunology.

Immunohistology of lymph nodes draining local skin reactions (chancres) in sheep infected with Trypanosoma congolense.

J. Hopkins, D. Mwangi, A. Luckins, 1991, Journal of comparative pathology.

Monoclonal antibodies to the sheep analogues of human CD45 (leucocyte common antigen), MHC class I and CD5. Differential expression after lymphocyte activation in vivo.

B. Dutia, J. Hopkins, 1990, Veterinary immunology and immunopathology.

Differential expression of pattern recognition receptors in sheep tissues and leukocyte subsets.

J. Hopkins, R. Dalziel, A. Gossner, 2007, Veterinary immunology and immunopathology.

Cellular phenotypes in Trypanosoma congolense infected sheep: The local skin reaction

J. Hopkins, D. Mwangi, A. Luckins, 1990, Parasite immunology.

MIycobacterium paratuberculosis

J. Hopkins, N. Morrison, 2022 .

Trypanosoma congolense infection in sheep: ultrastructural changes in the skin prior to development of local skin reactions.

J. Hopkins, D. Mwangi, A. Luckins, 1995, Veterinary parasitology.

Pathways and Genes Associated with Immune Dysfunction in Sheep Paratuberculosis

F. Chianini, J. Hopkins, C. Watkins, 2017, Scientific Reports.

Incremental generation of an EST set for the analysis of scrapie pathogenesis

J. Hopkins, A. Gossner, 2009 .

Role of lymph-borne cells in the early stages of scrapie agent dissemination from the skin.

N. Hunter, J. Hopkins, A. Gossner, 2006, Veterinary immunology and immunopathology.

The effect of PrPSc accumulation on inflammatory gene expression within sheep peripheral lymphoid tissue

J. Hopkins, A. Gossner, 2015, Veterinary microbiology.

Variations in T cell transcription factor gene structure and expression associated with the two disease forms of sheep paratuberculosis

J. Hopkins, R. Dalziel, C. Watkins, 2016, Veterinary Research.

Expression profiling reveals differences in immuno-inflammatory gene expression between the two disease forms of sheep paratuberculosis.

J. Hopkins, J. Smeed, C. Watkins, 2010, Veterinary immunology and immunopathology.

Antigen-induced non-specific suppressor factor in sheep efferent lymph is prostaglandin E2.

J. Hopkins, I. Mcconnell, J. Raniwalla, 1981, Immunology.

Differential expression of Prnp and Sprn in scrapie infected sheep also reveals Prnp genotype specific differences.

N. Hunter, J. Hopkins, A. Gossner, 2009, Biochemical and biophysical research communications.

Variable exon usage of differentially-expressed genes associated with resistance of sheep to Teladorsagia circumcincta

J. Hopkins, A. Gossner, H. Wilkie, 2015, Veterinary parasitology.

Early stages of infection with Trypanosoma congolense: parasite kinetics and expression of metacyclic variable antigen types.

J. Hopkins, D. Mwangi, D. Sutherland, 1994, Acta tropica.

Stability of metacyclic variable antigen types (M-VATs) during the early stages of infection with Trypanosoma congolense.

J. Hopkins, A. Luckins, C. Ross, 1990, Acta tropica.

Changes in peripheral blood lymphocyte subpopulations and parasite-specific antibody responses in Trypanosoma evansi infection of sheep

J. Hopkins, A. Luckins, Denis Nnabuike Onah, 1999, Parasitology Research.

Concurrent Infection With the Filarial Helminth Litomosoides sigmodontis Attenuates or Worsens Influenza A Virus Pathogenesis in a Stage-Dependent Manner

B. Dutia, J. Hopkins, Johanna A. Knipper, 2022, Frontiers in Immunology.

Lymphocyte traffic through antigen-stimulated lymph nodes. II. Role of Prostaglandin E2 as a mediator of cell shutdown.

J. Pearson, J. Hopkins, I. Mcconnell, 1981, Immunology.

The immunology and genetics of resistance of sheep to Teladorsagia circumcincta

J. Hopkins, A. Gossner, V. Venturina, 2013, Veterinary Research Communications.

Mucosal Expression of T Cell Gene Variants Is Associated with Differential Resistance to Teladorsagia circumcincta

J. Hopkins, A. Gossner, H. Wilkie, 2016, PloS one.

Patterns of major histocompatibility complex class II expression on T cell subsets in different immunological compartments 1. Expression on resting T cells

B. Dutia, J. Hopkins, I. Mcconnell, 1993, European journal of immunology.

Specific selection of antigen-reactive lymphocytes into antigenically stimulated lymph nodes in sheep

P. Lachmann, J. Hopkins, I. Mcconnell, 1981, The Journal of experimental medicine.

Digital gene expression analysis of gastrointestinal helminth resistance in Scottish blackface lambs

J. Pemberton, J. Pemberton, D. Beraldi, 2011, Molecular ecology.

Ov2 is a modulator of OvHV-2 RTA mediated gene expression

J. Ferguson, K. Nightingale, J. Hopkins, 2019, Veterinary Research Communications.

Gene Gun‐delivered pGM‐CSF Adjuvant Induces Enhanced Emigration of two Dendritic Cell Subsets from the Skin

J. Hopkins, R. Dalziel, C. Watkins, 2007, Scandinavian journal of immunology.

Afferent lymph dendritic cells: a model for antigen capture and presentation in vivo.

J. Hopkins, R. Bujdoso, I. Mcconnell, 1990, International reviews of immunology.

Molecular immunology--gene regulation and signal transduction.

J. Hopkins, 2002, Veterinary immunology and immunopathology.

Transcriptome analysis of CNS immediately before and after the detection of PrPSc in SSBP/1 sheep scrapie

J. Hopkins, A. Gossner, 2014, Veterinary microbiology.

Differential expression of pattern recognition receptors in the three pathological forms of sheep paratuberculosis.

J. Hopkins, R. Dalziel, J. Smeed, 2008, Microbes and infection.

Differential expression of pattern recognition receptors during the development of foetal sheep.

J. Hopkins, R. Dalziel, A. Gossner, 2008, Developmental and comparative immunology.

Monoclonal antibodies to sheep lymphocytes. I. Identification of MHC class II molecules on lymphoid tissue and changes in the level of class II expression on lymph-borne cells following antigen stimulation in vivo.

B. Dutia, J. Hopkins, I. Mcconnell, 1986, Immunology.

Expression of sheep interleukin 23 (IL23A, alpha subunit p19) in two distinct gastrointestinal diseases.

J. Hopkins, C. Watkins, A. Gossner, 2012, Veterinary immunology and immunopathology.

Selective entry of immunoblasts into gut from intestinal lymph

J. Hopkins, J. Hall, 1976, Nature.

Transcriptional profiling of peripheral lymphoid tissue reveals genes and networks linked to SSBP/1 scrapie pathology in sheep.

N. Hunter, J. Foster, J. Hopkins, 2011, Veterinary microbiology.

Gene expression analysis in distinct regions of the central nervous system during the development of SSBP/1 sheep scrapie.

N. Hunter, J. Foster, J. Fazakerley, 2011, Veterinary microbiology.

The PrP(C) C1 fragment derived from the ovine A136R154R171PRNP allele is highly abundant in sheep brain and inhibits fibrillisation of full-length PrP(C) protein in vitro.

N. Hunter, W. Goldmann, M. Tranulis, 2013, Biochimica et biophysica acta.

Haematological changes in sheep experimentally infected with Trypanosoma evansi

J. Hopkins, A. Luckins, D. N. Onah, 1996, Parasitology Research.

Non‐random migration of cd4 and cd8 t cells: changes in the cd4: cd8 ratio and interleukin 2 responsiveness of efferent lymph cells following in vivo antigen challenge

D. Allen, J. Hopkins, R. Bujdoso, 1989, European journal of immunology.

Possible role of surface Ig in non-random recirculation of small lymphocytes

J. Hopkins, R. Scollay, Joe Hall, 1976, Nature.

Analysis of the fine specificities of sheep major histocompatibility complex class II-specific monoclonal antibodies using mouse L-cell transfectants.

B. Dutia, J. Hopkins, K. Ballingall, 2009, Animal genetics.

Cell phenotypes in the efferent lymph of sheep persistently infected with Border disease virus

J. Hopkins, G. Entrican, I. Mcconnell, 1992, Clinical and Experimental Immunology.

Induction of CD4+CD8+ double positive T cells and increase in CD5+ B cells in efferent lymph in sheep infected with Trypanosoma evansi

J. Hopkins, A. Luckins, D. N. Onah, 1998, Parasite immunology.

Increase in CD5+ B cells and depression of immune responses in sheep infected with Trypanosoma evansi.

J. Hopkins, A. Luckins, D. N. Onah, 1998, Veterinary immunology and immunopathology.

Effects of the depletion of CD8(+) T cells and monocytes on the proliferative responses of peripheral blood leucocytes from Trypanosoma evansi-infected sheep.

J. Hopkins, A. Luckins, D. N. Onah, 2000, Veterinary parasitology.

Ruminant cluster CD14.

J. Hopkins, P. Berthon, 1996, Veterinary immunology and immunopathology.

Identification of the sheep homologue of the monocyte cell surface molecule--CD14.

V. Gupta, J. Hopkins, R. Dalziel, 1996, Veterinary immunology and immunopathology.

Syngeneic antitumour antibodies in rats: clearance of cell-bound antibody in vivo and in vitro.

J. Hopkins, S. Hobbs, C. Dean, 1982, British Journal of Cancer.

Migration pathways of lymphoid cells with reference to the gut, immunoglobulins and lymphomata [proceedings].

J. Hopkins, J. Hall, E. Orlans, 1977, Biochemical Society transactions.

A novel cell surface proliferation‐associated marker expressed on T cells and up‐regulated on germinal center B cells

J. Hopkins, E. Glass, A. Nichani, 1998, Journal of Leukocyte Biology.

Expressed gene sequences of two variants of sheep interleukin-25.

J. Hopkins, A. Gossner, V. Venturina, 2011, Veterinary immunology and immunopathology.

Variable expression of major histocompatibility complex class II in the domestic cat.

C. K. Grant, R. Else, J. Hopkins, 1995, Research in veterinary science.

Lymphocyte traffic through lymph nodes during cell shutdown.

P. Lachmann, J. Hopkins, I. Mcconnell, 1980, Ciba Foundation symposium.

Gene expression profiling of ovine keratinocytes stimulated with Psoroptes ovis mite antigen – a preliminary study

T. McNeilly, J. Hopkins, J. Huntley, 2009, Parasite immunology.

Novel virus-encoded microRNA molecules expressed by ovine herpesvirus 2-immortalized bovine T-cells.

J. Hopkins, R. Dalziel, G. Russell, 2012, The Journal of general virology.

Ovine herpesvirus-2-encoded microRNAs target virus genes involved in virus latency.

D. Shaw, J. Hopkins, Finn E. Grey, 2014, The Journal of general virology.

A candidate gene approach to study nematode resistance traits in naturally infected sheep

J. Pemberton, R. Houston, J. Hopkins, 2017, Veterinary parasitology.

Effects of Trypanosoma evansi on the output of cells from a lymph node draining the site of Pasteurella haemolytica vaccine administration.

J. Hopkins, A. Luckins, D. N. Onah, 1997, Journal of comparative pathology.

Explorer Differential cytokine gene expression profiles in the three pathological forms of sheep paratuberculosis

J. Hopkins, J. Smeed, C. Watkins, 2017 .

Summary of workshop findings for leukocyte antigens of sheep.

C. Mackay, M. Brandon, B. Dutia, 1991, Veterinary immunology and immunopathology.

Regulation of Ov2 by virus encoded microRNAs

K. Nightingale, J. Hopkins, R. Dalziel, 2019, Veterinary Research Communications.

Development and validation of an oligonucleotide microarray for immuno-inflammatory genes of ruminants

J. Hopkins, K. Stevenson, C. Watkins, 2008, Veterinary Research Communications.