A. Dhir

发表

Feed backwards model for microRNA processing and splicing in plants

N. Proudfoot, A. Dhir, Nick J Proudfoot, 2013, EMBO reports.

RNA structure is a key regulatory element in pathological ATM and CFTR pseudoexon inclusion events

E. Buratti, F. Baralle, M. Lewandowska, 2007, Nucleic acids research.

The intronic splicing code: multiple factors involved in ATM pseudoexon definition

R. Lührmann, E. Buratti, F. Baralle, 2010, The EMBO journal.

TDP‐43 regulates its mRNA levels through a negative feedback loop

Jernej Ule, Andrea D'Ambrogio, Marco Baralle, 2011, The EMBO journal.

Propofol in the treatment of refractory migraine headaches

A. Dhir, 2016, Expert review of neurotherapeutics.

Antidepressant-like effect of 17beta-estradiol: involvement of dopaminergic, serotonergic, and (or) sigma-1 receptor systems.

S. Kulkarni, A. Dhir, S. K. Kulkarni, 2008, Canadian journal of physiology and pharmacology.

Venlafaxine reverses chronic fatigue-induced behavioral, biochemical and neurochemical alterations in mice

S. Kulkarni, A. Dhir, Ashish Dhir, 2008, Pharmacology Biochemistry and Behavior.

Protective effect of cyclooxygenase‐2 (COX‐2) inhibitors but not non‐selective cyclooxygenase (COX)‐inhibitors on ethanol withdrawal‐induced behavioural changes

S. Kulkarni, A. Dhir, P. Naidu, 2005, Addiction biology.

Involvement of sigma-1 receptor modulation in the antidepressant action of venlafaxine

S. Kulkarni, A. Dhir, 2007, Neuroscience Letters.

Optimal antisense target reducing INS intron 1 retention is adjacent to a parallel G quadruplex

J. Královičová, I. Vořechovský, E. Buratti, 2014, Nucleic acids research.

Systemic administration of adenosine ameliorates pentylenetetrazol‐induced chemical kindling and secondary behavioural and biochemical changes in mice

S. Kulkarni, A. Dhir, K. K. Akula, 2007, Fundamental & clinical pharmacology.

Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice.

S. Kulkarni, A. Dhir, K. K. Akula, 2009, Methods and findings in experimental and clinical pharmacology.

Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A

C. Bodemer, C. Wouters, Y. Crow, 2021, bioRxiv.

Enhanced cGAS-STING–dependent interferon signaling associated with mutations in ATAD3A

C. Bodemer, C. Wouters, Y. Crow, 2021, The Journal of experimental medicine.

Effect of cyclooxygenase inhibitors on pentylenetetrazol (PTZ)-induced convulsions: Possible mechanism of action

S. Kulkarni, A. Dhir, P. Naidu, 2006, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Effect of cyclooxygenase-2 (COX-2) inhibitors in various animal models (bicuculline, picrotoxin, maximal electroshock-induced convulsions) of epilepsy with possible mechanism of action.

S. Kulkarni, A. Dhir, P. Naidu, 2006, Indian journal of experimental biology.

σ-1 receptors in major depression and anxiety

S. Kulkarni, A. Dhir, 2009, Expert review of neurotherapeutics.

Withania somnifera: An Indian ginseng

S. Kulkarni, A. Dhir, 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Natural polyphenols in preclinical models of epilepsy

A. Dhir, 2020, Phytotherapy research : PTR.

Effect of preferential cyclooxygenase-2 (COX-2) inhibitor against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced striatal lesions in rats: behavioral, biochemical and histological evidences.

Anil Kumar, Amit Gupta, A. Dhir, 2010, Indian journal of experimental biology.

Investigational drugs for treating major depressive disorder

A. Dhir, 2017, Expert opinion on investigational drugs.

Memantine delayed N‐methyl‐D‐aspartate ‐induced convulsions in neonatal rats

K. Chopra, A. Dhir, 2015, Fundamental & clinical pharmacology.

Edinburgh Research Explorer RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination

N. Proudfoot, Somdutta Dhir, A. Dhir, 2018 .

Seizure protection by intrapulmonary delivery of midazolam in mice

M. Rogawski, A. Dhir, D. Żółkowska, 2013, Neuropharmacology.

The efficacy of vortioxetine for the treatment of major depressive disorder

A. Dhir, J. Sarvaiya, 2014, Expert review of neurotherapeutics.

Novel variations in the signal peptide region of transforming growth factor β1 gene in patients with hepatitis: a brief report from India

R. Arora, R. Bamezai, A. Dhir, 2005, International journal of immunogenetics.

EFFECT OF NAPROXEN, A NON‐SELECTIVE CYCLO‐OXYGENASE INHIBITOR, ON PENTYLENETETRAZOL‐INDUCED KINDLING IN MICE

S. Kulkarni, A. Dhir, P. Naidu, 2005, Clinical and experimental pharmacology & physiology.

Effect of withdrawal of diazepam or morphine treatment on gastric motility (charcoal meal test) in mice: possible role of different central and peripheral receptors.

S. Kulkarni, A. Dhir, Anu Kaushal, 2007, Indian journal of experimental biology.

Protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice.

S. Kulkarni, A. Dhir, S. V. Padi, 2006, European journal of pharmacology.

Anticonvulsant potencies of the enantiomers of the neurosteroids androsterone and etiocholanolone exceed those of the natural forms

M. Rogawski, A. Dhir, K. Krishnan, 2014, Psychopharmacology.

Novel discoveries in understanding the complexities of epilepsy and major depression

A. Dhir, 2010, Expert opinion on therapeutic targets.

Antidepressant-like effect of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a putative trace amine receptor ligand involves l-arginine–nitric oxide–cyclic guanosine monophosphate pathway

S. Kulkarni, A. Dhir, 2011, Neuroscience Letters.

Neuroprotective effect of nimesulide, a preferential COX-2 inhibitor, against pentylenetetrazol (PTZ)-induced chemical kindling and associated biochemical parameters in mice

S. Kulkarni, A. Dhir, P. Naidu, 2007, Seizure.

Effect of rofecoxib, a cyclo‐oxygenase‐2 inhibitor, on various biochemical parameters of brain associated with pentylenetetrazol‐induced chemical kindling in mice

S. Kulkarni, A. Dhir, P. Naidu, 2006, Fundamental & clinical pharmacology.

Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication

Brad A. Hobson, D. Harvey, M. Rogawski, 2020, Neurobiology of Disease.

Rofecoxib potentiates the anticonvulsant effect of topiramate

S. Kulkarni, A. Dhir, K. K. Akula, 2008, Inflammopharmacology.

Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor potentiates the anticonvulsant activity of tiagabine against pentylenetetrazol-induced convulsions in mice

S. Kulkarni, A. Dhir, 2006, InflammoPharmacology.

Functional IFNG polymorphism in intron 1 in association with an increased risk to promote sporadic breast cancer

A. Dhir, A. Ranjan, R. Bamezai, 2005, Immunogenetics.

An update of cyclooxygenase (COX)-inhibitors in epilepsy disorders

A. Dhir, 2018, Expert opinion on investigational drugs.

Nimesulide, a cyclooxygenase-2 (COX-2) inhibitor counteracts immobilization stress-induced alterations in different behavioral and biochemical parameters in mice

S. Kulkarni, A. Dhir, 2007, Inflammation Research.

Risperidone, an atypical antipsychotic enhances the antidepressant-like effect of venlafaxine or fluoxetine: Possible involvement of alpha-2 adrenergic receptors

S. Kulkarni, A. Dhir, 2008, Neuroscience Letters.

Curcumin in epilepsy disorders

A. Dhir, 2018, Phytotherapy research : PTR.

Characterization of Seizures Induced by Acute and Repeated Exposure to Tetramethylenedisulfotetramine

Mark R. McCoy, M. Rogawski, B. Hammock, 2012, Journal of Pharmacology and Experimental Therapeutics.

On the anticonvulsant effect of allopregnanolone (a neurosteroid) in neonatal rats.

K. Chopra, A. Dhir, 2015, Life sciences.

Perampanel, a potent AMPA receptor antagonist, protects against tetramethylenedisulfotetramine-induced seizures and lethality in mice: comparison with diazepam

M. Rogawski, A. Dhir, D. Żółkowska, 2021, Archives of Toxicology.

Allopregnanolone and perampanel as adjuncts to midazolam for treating diisopropylfluorophosphate‐induced status epilepticus in rats

D. Harvey, M. Rogawski, D. Tancredi, 2020, Annals of the New York Academy of Sciences.

Seizure Protection by Intrapulmonary Delivery of Propofol Hemisuccinate

M. Rogawski, R. Murphy, A. Dhir, 2011, Journal of Pharmacology and Experimental Therapeutics.

Effect of Withania somnifera Dunal root extract against pentylenetetrazol seizure threshold in mice: possible involvement of GABAergic system.

S. Kulkarni, A. Dhir, K. K. Akula, 2008, Indian journal of experimental biology.

Pentylenetetrazol (PTZ) Kindling Model of Epilepsy

A. Dhir, 2012, Current protocols in neuroscience.

On the mechanism of antidepressant-like action of berberine chloride.

S. Kulkarni, A. Dhir, 2008, European journal of pharmacology.

Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant activity of berberine chloride.

S. Kulkarni, A. Dhir, 2007, European journal of pharmacology.

Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders

A. Dhir, Ashish Dhir, S K Kulkarni, 2010, Phytotherapy research : PTR.

Pro-convulsant effect of cefazolin sodium against pentylenetetrazol- or picrotoxin-induced convulsions in mice.

S. Kulkarni, A. Dhir, K. K. Akula, 2007, Indian journal of experimental biology.

Possible involvement of sigma‐1 receptors in the anti‐immobility action of bupropion, a dopamine reuptake inhibitor

S. Kulkarni, A. Dhir, 2008, Fundamental & clinical pharmacology.

Involvement of l-arginine–nitric oxide–cyclic guanosine monophosphate pathway in the antidepressant-like effect of venlafaxine in mice

S. Kulkarni, A. Dhir, 2007, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Nitric oxide and major depression.

S. Kulkarni, A. Dhir, Sushrut Krishnaji Kulkarni, 2011, Nitric oxide : biology and chemistry.

Potential of Polyphenols in the Treatment of Major Depression

A. Dhir, 2017 .

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

A. Munnich, M. Teitell, Y. Crow, 2018, Nature.

Mechanisms of action of antiseizure drugs.

M. Rogawski, R. Macdonald, A. Dhir, 2012, Handbook of clinical neurology.

Mechanisms of Action of Antiseizure Drugs (Chapter 39)

M. Rogawski, R. Macdonald, A. Dhir, 2012 .

Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo

A. Pajak, A. Dhir, R. Wibom, 2019, PLoS genetics.

Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection.

N. Proudfoot, E. Buratti, F. Baralle, 2012, Genes & development.

Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence

N. Proudfoot, G. Dujardin, Takayuki Nojima, 2018, Molecular cell.

Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs

Maria Carmo-Fonseca, M. Carmo-Fonseca, N. Proudfoot, 2017, Molecular cell.

Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats

S. Kulkarni, A. Dhir, K. K. Akula, 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Dhir, Ashish and Dhir, Somdutta and Proudfoot, Nick J. and Jopling, Catherine L. (2015) Microprocessor mediates transcriptional termination of long noncoding RNA

N. Proudfoot, Somdutta Dhir, C. Jopling, 2017 .

Microprocessor mediates transcriptional termination in long noncoding microRNA genes

N. Proudfoot, Somdutta Dhir, C. Jopling, 2015, Nature Structural &Molecular Biology.

RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination

N. Proudfoot, Somdutta Dhir, A. Dhir, 2018, Molecular cell.

Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor increases pentylenetetrazol seizure threshold in mice: Possible involvement of adenosinergic mechanism

S. Kulkarni, A. Dhir, K. K. Akula, 2008, Epilepsy Research.

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

Martin A. M. Reijns, Y. Crow, H. Van Esch, 2020, Nature Genetics.

Alternative splicing: role of pseudoexons in human disease and potential therapeutic strategies

E. Buratti, A. Dhir, 2010, The FEBS journal.

Antagonistic Activity of Ascorbic Acid (Vitamin C) on Dopaminergic Modulation: Apomorphine-Induced Stereotypic Behavior in Mice

S. Kulkarni, A. Dhir, C. Deshpande, 2006, Pharmacology.

Propofol hemisuccinate suppresses cortical spreading depression

Michael A. Rogawski, M. Rogawski, A. Dhir, 2012, Neuroscience Letters.

Animal models of tardive dyskinesia.

S. Kulkarni, A. Dhir, 2011, International review of neurobiology.

Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats

Anil Kumar, Amit Gupta, A. Dhir, 2009, Pharmacology Biochemistry and Behavior.

SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications

P. Vyas, Ulrike Schulze, A. Schuh, 2020, Leukemia.

An Overview of Curcumin in Neurological Disorders

A. Dhir, S. K. Kulkarni, Sushrut Krishnaji Kulkarni, 2010, Indian journal of pharmaceutical sciences.

Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice.

S. Kulkarni, A. Dhir, K. K. Akula, 2008, European journal of pharmacology.

Determination of minimal steady‐state plasma level of diazepam causing seizure threshold elevation in rats

M. Rogawski, A. Dhir, 2018, Epilepsia.

Current investigational drugs for major depression

S. Kulkarni, A. Dhir, 2009 .

Current investigational drugs for major depression.

S. Kulkarni, A. Dhir, 2009, Expert opinion on investigational drugs.

Pre- and post-exposure talampanel (GYKI 53773) against kainic acid seizures in neonatal rats

A. Dhir, Vishal Chavda, Vishal Chavda, 2016, Pharmacological reports : PR.

Cannabidiol in Refractory Epilepsy

A. Dhir, 2018 .

Significantly higher serologic responses of Chlamydia trachomatis B group serovars versus C and I serogroups.

S. Kulkarni, A. Dhir, 2009 .

Potentials of Curcumin as an Antidepressant

A. Dhir, K. K. Akula, S. K. Kulkarni, 2009, TheScientificWorldJournal.

Natural polyphenols in the management of major depression

A. Dhir, Y. Agrawal, L. Pathak, 2013, Expert opinion on investigational drugs.

Effect of various classes of antidepressants in behavioral paradigms of despair

S. Kulkarni, A. Dhir, 2007, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Curcumin in Neurological Disorders: An Overview

A. Dhir, 2019, Curcumin for Neurological and Psychiatric Disorders.

The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity

D. Harvey, M. Rogawski, A. Dhir, 2020, Archives of Toxicology.

Curcumin potentiates the anti-inflammatory activity of cyclooxygenase inhibitors in the cotton pellet granuloma pouch model.

K. Chopra, A. Kuhad, A. Dhir, 2009, Methods and findings in experimental and clinical pharmacology.

Cyclooxygenase in epilepsy: from perception to application.

S. Kulkarni, A. Dhir, 2009, Drugs of today.

Ascorbic Acid Inhibits Development of Tolerance and Dependence to Opiates in Mice: Possible Glutamatergic or Dopaminergic Modulation

A. Dhir, S. K. Kulkarni, C. Deshpande, 2008, Indian journal of pharmaceutical sciences.

Possible involvement of nitric oxide (NO) signaling pathway in the antidepressant-like effect of MK-801(dizocilpine), a NMDA receptor antagonist in mouse forced swim test.

S. Kulkarni, A. Dhir, 2008, Indian journal of experimental biology.

Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor.

S. Kulkarni, A. Dhir, 2007, European journal of pharmacology.

Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice.

S. Kulkarni, A. Dhir, K. K. Akula, 2009, Methods and findings in experimental and clinical pharmacology.

Role of neurosteroids in the anticonvulsant activity of midazolam

M. Rogawski, A. Dhir, 2012, British journal of pharmacology.

Protective effect of non-selective and selective COX-2-inhibitors in acute immobilization stress-induced behavioral and biochemical alterations.

Anil Kumar, A. Dhir, B. Kumari, 2007, Pharmacological reports : PR.

Effect of systemic administration of adenosine on brain adenosine levels in pentylenetetrazol-induced seizure threshold in mice

S. Kulkarni, A. Dhir, M. Bishnoi, 2007, Neuroscience Letters.

Involvement of sigma (σ1) receptors in modulating the anti-depressant effect of neurosteroids (dehydroepiandrosterone or pregnenolone) in mouse tail-suspension test

A. Dhir, S. Kulkarni, 2008, Journal of psychopharmacology.

Research Article Rofecoxib potentiates the anticonvulsant effect of topiramate

S. Kulkarni, A. Dhir, K. K. Akula, 2008 .

Mitochondrial double-stranded RNA triggers antiviral signalling in humans

A. Munnich, M. Teitell, A. Rötig, 2018, Nature.

Effect of Addition of Yohimbine (Alpha-2-Receptor Antagonist) to the Antidepressant Activity of Fluoxetine or Venlafaxine in the Mouse Forced Swim Test

S. Kulkarni, A. Dhir, Sushrut Krishnaji Kulkarni, 2007, Pharmacology.

NUCLEIC ACIDS AND IMMUNITY

N. Proudfoot, J. Rehwinkel, Takayuki Nojima, 2017 .

Involvement of dopamine (DA)/serotonin (5-HT)/sigma (σ) receptor modulation in mediating the antidepressant action of ropinirole hydrochloride, a D2/D3 dopamine receptor agonist

S. Kulkarni, A. Dhir, 2007, Brain Research Bulletin.

Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo

A. Dhir, R. Wibom, C. Freyer, 2019, PLoS genetics.

Natural polyphenols in the management of major depression

A. Dhir, Y. Agrawal, L. Pathak, 2013, Expert opinion on investigational drugs.

Current investigational drugs for major depression

S. Kulkarni, A. Dhir, 2009, Expert opinion on investigational drugs.

Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders

A. Dhir, S. K. Kulkarni, 2010, Phytotherapy research : PTR.

Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats

S. Kulkarni, A. Dhir, K. K. Akula, 2008, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Involvement of l-arginine–nitric oxide–cyclic guanosine monophosphate pathway in the antidepressant-like effect of venlafaxine in mice

S. Kulkarni, A. Dhir, 2007, Progress in Neuro-Psychopharmacology and Biological Psychiatry.