D. Waugh

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Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage.

D. Court, J. Błaszczyk, X. Ji, 2001, Structure.

Characterization of a 78-residue fragment of c-Raf-1 that comprises a minimal binding domain for the interaction with Ras-GTP.

A. Neri, J. E. Losardo, D. Waugh, 1994, The Journal of biological chemistry.

An overview of enzymatic reagents for the removal of affinity tags

D. Waugh, 2011, Protein Expression and Purification.

Escherichia coli maltose‐binding protein is uncommonly effective at promoting the solubility of polypeptides to which it is fused

D. Waugh, R. Kapust, 1999, Protein science : a publication of the Protein Society.

Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency.

D. E. Anderson, T. Copeland, D. Waugh, 2001, Protein engineering.

Maltose-binding protein as a solubility enhancer.

D. Waugh, J. Fox, 2003, Methods in molecular biology.

Structural Insight into the Mechanism of Double-Stranded RNA Processing by Ribonuclease III

D. Court, J. Gan, X. Ji, 2006, Cell.

A novel class of FokI restriction endonuclease mutants that cleave hemi-methylated substrates.

R. Sauer, D. Waugh, Robert T. Sauer, 1994, The Journal of biological chemistry.

Single amino acid substitutions uncouple the DNA binding and strand scission activities of Fok I endonuclease.

R. Sauer, D. Waugh, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Biomolecular Interactions of Small‐molecule Inhibitors Affecting the YopH Protein Tyrosine Phosphatase

Bryan M. Zhao, J. Tropea, D. Waugh, 2013, Chemical biology & drug design.

A spring-loaded state of NusG in its functional cycle is suggested by X-ray crystallography and supported by site-directed mutants.

D. Court, W. Guo, X. Ji, 2003, Biochemistry.

Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening.

Y. Pommier, J. Tropea, D. Waugh, 2019, Nucleic acids research.

X‐ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper‐dependent hydrophobic pocket

Y. Pommier, R. Shoemaker, J. Tropea, 2011, FEBS letters.

Crystal structure of UDP-glucose pyrophosphorylase from Yersinia pestis, a potential therapeutic target against plague.

D. Waugh, Morgan E. Gibbs, G. Lountos, 2019, Acta crystallographica. Section F, Structural biology communications.

Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9.

W. M. Hewitt, R. Nussinov, B. Ma, 2016, Angewandte Chemie.

New protein fold revealed by a 1.65 Å resolution crystal structure of Francisella tularensis pathogenicity island protein IglC

D. Waugh, B. P. Austin, F. Schubot, 2007, Protein science : a publication of the Protein Society.

Expression, purification, refolding, and characterization of recombinant human interleukin-13: utilization of intracellular processing.

L. Pannell, E. Eisenmesser, R. Byrd, 2000, Protein expression and purification.

Characterization of a broadly specific cadaverine N-hydroxylase involved in desferrioxamine B biosynthesis in Streptomyces sviceus

L. Giddings, J. Tropea, D. Waugh, 2021, PloS one.

Controlled intracellular processing of fusion proteins by TEV protease.

D. Waugh, R. Kapust, D S Waugh, 2000, Protein expression and purification.

A dual protease approach for expression and affinity purification of recombinant proteins

D. Waugh, S. Raran-Kurussi, 2016, Analytical Biochemistry.

Enhancing the solubility of recombinant proteins in Escherichia coli by using hexahistidine-tagged maltose-binding protein as a fusion partner.

J. Tropea, D. Waugh, P. Sun, 2011, Methods in molecular biology.

Hexahistidine-tagged maltose-binding protein as a fusion partner for the production of soluble recombinant proteins in Escherichia coli.

D. Waugh, B. P. Austin, Sreedevi Nallamsetty, 2009, Methods in molecular biology.

A generic protocol for the expression and purification of recombinant proteins in Escherichia coli using a combinatorial His6-maltose binding protein fusion tag

D. Waugh, Sreedevi Nallamsetty, 2007, Nature Protocols.

Solubility-enhancing proteins MBP and NusA play a passive role in the folding of their fusion partners.

D. Waugh, Sreedevi Nallamsetty, 2006, Protein expression and purification.

Crystallization and preliminary X-ray diffraction studies of NusG, a protein shared by the transcription and translation machines.

D. E. Anderson, W. Guo, X. Ji, 2002, Acta crystallographica. Section D, Biological crystallography.

Structure-assisted discovery of Variola major H1 phosphatase inhibitors.

J. Tropea, D. Waugh, J. Phan, 2007, Acta crystallographica. Section D, Biological crystallography.

Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen

Michael S. Lee, M. A. Olson, D. Waugh, 2015, Scientific Reports.

Human cytolytic T cell recognition of Yersinia pestis virulence proteins that target innate immune responses.

J. Tropea, D. Waugh, T. Kissner, 2006, The Journal of infectious diseases.

Structure and function of the histone chaperone CIA / ASF 1 complexed with histones H 3 and H 4

C. Ban, A. Wlodawer, M. Horikoshi, 2008 .

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of macrophage growth locus A (MglA) protein from Francisella tularensis.

X. Ji, D. Waugh, B. P. Austin, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Thermostable tag (TST) protein expression system: engineering thermotolerant recombinant proteins and vaccines.

D. Waugh, James A. Williams, Aaron E. Carnes, 2011, Journal of biotechnology.

Expression and Purification of Recombinant Proteins in Escherichia coli with a His6 or Dual His6-MBP Tag

D. Waugh, S. Raran-Kurussi, 2017, Methods in molecular biology.

The remarkable solubility-enhancing power of Escherichia coli maltose-binding protein.

D. Waugh, 2016, Postepy biochemii.

Positional effects of fusion partners on the yield and solubility of MBP fusion proteins.

D. Waugh, S. Raran-Kurussi, Karina Keefe, 2015, Protein expression and purification.

D. Waugh, S. Raran-Kurussi, 2014, Biotechnology and bioengineering.

Rescuing aggregation-prone proteins in Escherichia coli with a dual His₆-MBP tag.

D. Waugh, D. Needle, 2014, Methods in molecular biology.

Processive degradation of nascent polypeptides, triggered by tandem AGA codons, limits the accumulation of recombinant tobacco etch virus protease in Escherichia coli BL21(DE3).

K. M. Routzahn, D. Waugh, R. Kapust, 2002, Protein expression and purification.

Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitors.

K. No, Ky-Youb Nam, Zhon-Yin Zhang, 2005, Bioorganic & medicinal chemistry letters.

Overproduction, purification, crystallization and preliminary X-ray diffraction analysis of YopM, an essential virulence factor extruded by the plague bacterium Yersinia pestis.

D. E. Anderson, K. M. Routzahn, D. Waugh, 2000, Acta crystallographica. Section D, Biological crystallography.

Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88

G. Ruthel, J. Rebek, D. Waugh, 2012, PloS one.

The 8-Nucleotide-long RNA:DNA Hybrid Is a Primary Stability Determinant of the RNA Polymerase II Elongation Complex*

M. Kashlev, D. Waugh, M. Kireeva, 2000, The Journal of Biological Chemistry.

Characterization of four orthologs of stringent starvation protein A.

X. Ji, Mi Li, K. M. Routzahn, 2003, Acta crystallographica. Section D, Biological crystallography.

Structural Basis for the Function of Stringent Starvation Protein A as a Transcription Factor*

X. Ji, Mi Li, D. Jin, 2005, Journal of Biological Chemistry.

Catalysis by RNA

N. Pace, D. Waugh, 1986, BioEssays : news and reviews in molecular, cellular and developmental biology.

A generic method for the production of recombinant proteins in Escherichia coli using a dual hexahistidine-maltose-binding protein affinity tag.

J. Tropea, D. Waugh, S. Cherry, 2007, Methods in molecular biology.

Mutations that alter the equilibrium between open and closed conformations of Escherichia coli maltose-binding protein impede its ability to enhance the solubility of passenger proteins.

D. Waugh, David S Waugh, Sreedevi Nallamsetty, 2007, Biochemical and biophysical research communications.

Structural Basis for the Substrate Specificity of Tobacco Etch Virus Protease*

A. Wlodawer, Mi Li, A. Zdanov, 2002, The Journal of Biological Chemistry.

The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague.

Z. Derewenda, A. Mateja, K. M. Routzahn, 2004, Structure.

Specificity Studies of the Venezuelan Equine Encephalitis Virus Non-Structural Protein 2 Protease Using Recombinant Fluorescent Substrates

D. Waugh, J. Tőzsér, J. Mótyán, 2020, International journal of molecular sciences.

A stepwise model for double‐stranded RNA processing by ribonuclease III

D. Court, J. Gan, X. Ji, 2007, Molecular microbiology.

Solution structure of the Ras-binding domain of c-Raf-1 and identification of its Ras interaction surface.

D. Fry, R. Palermo, V. Madison, 1995, Biochemistry.

Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy.

Y. Pommier, R. Shoemaker, J. Tropea, 2011, Journal of structural biology.

Cellular Inhibition of Checkpoint Kinase 2 (Chk2) and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor PV1019 [7-Nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]

Y. Pommier, A. Monks, R. Shoemaker, 2009, Journal of Pharmacology and Experimental Therapeutics.

The molecular mechanism of dsRNA processing by a bacterial Dicer.

X. Ji, Shuo Gu, He Song, 2019, Nucleic acids research.

RNase III: Genetics and function; structure and mechanism.

N. Costantino, D. Court, J. Gan, 2013, Annual review of genetics.

Intermediate states of ribonuclease III in complex with double-stranded RNA.

D. Court, J. Gan, X. Ji, 2005, Structure.

Noncatalytic assembly of ribonuclease III with double-stranded RNA.

D. Court, J. Błaszczyk, J. Gan, 2004, Structure.

Structure of the Yersinia pestis type III secretion chaperone SycH in complex with a stable fragment of YscM2.

J. Tropea, D. Waugh, J. Phan, 2004, Acta crystallographica. Section D, Biological crystallography.

Overproduction, purification and structure determination of human dual-specificity phosphatase 14.

J. Tropea, D. Waugh, S. Cherry, 2009, Acta crystallographica. Section D, Biological crystallography.

The design and catalytic properties of a simplified ribonuclease P RNA.

N. Pace, D. Waugh, C. Green, 1989, Science.

Interaction of phosphorylated FcepsilonRIgamma immunoglobulin receptor tyrosine activation motif-based peptides with dual and single SH2 domains of p72syk. Assessment of binding parameters and real time binding kinetics.

Z. Zhao, A. Gilfillan, D. Waugh, 1996, The Journal of biological chemistry.

Structure of human dual-specificity phosphatase 27 at 2.38 Å resolution.

J. Tropea, D. Waugh, G. Lountos, 2011, Acta crystallographica. Section D, Biological crystallography.

Involvement of Domain II in Toxicity of Anthrax Lethal Factor*

Xudong Liang, D. Waugh, N. Duesbery, 2004, Journal of Biological Chemistry.

Differential effects of supplementary affinity tags on the solubility of MBP fusion proteins

K. M. Routzahn, D. Waugh, 2004, Journal of Structural and Functional Genomics.

The P1' specificity of tobacco etch virus protease.

T. Copeland, D. Waugh, R. Kapust, 2002, Biochemical and biophysical research communications.

Expression and purification of soluble His(6)-tagged TEV protease.

J. Tropea, D. Waugh, S. Cherry, 2009, Methods in molecular biology.

Differential temperature dependence of tobacco etch virus and rhinovirus 3C proteases.

J. Tropea, D. Waugh, J. Tözsér, 2013, Analytical biochemistry.

Structural determinants of tobacco vein mottling virus protease substrate specificity

D. Waugh, B. P. Austin, J. Tözsér, 2010, Protein science : a publication of the Protein Society.

Comparison of the substrate specificity of two potyvirus proteases

A. Wlodawer, T. Copeland, J. Tropea, 2005, The FEBS journal.

Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor

Yves Pommier, Y. Pommier, R. Shoemaker, 2008, Protein science : a publication of the Protein Society.

Structure of ERA in complex with the 3′ end of 16S rRNA: Implications for ribosome biogenesis

D. Court, X. Ji, J. Tropea, 2009, Proceedings of the National Academy of Sciences.

Crystal structure of the Yersinia pestis GTPase activator YopE

J. Tropea, K. M. Routzahn, D. Waugh, 2002, Protein science : a publication of the Protein Society.

Utilization of nitrophenylphosphates and oxime-based ligation for the development of nanomolar affinity inhibitors of the Yersinia pestis outer protein H (YopH) phosphatase.

D. Waugh, T. Burke, R. Ulrich, 2011, Journal of medicinal chemistry.

Three-dimensional structure of a macromolecular assembly that regulates type III secretion in Yersinia pestis.

M. W. Jackson, G. Plano, J. Tropea, 2005, Journal of molecular biology.

The Era GTPase recognizes the GAUCACCUCC sequence and binds helix 45 near the 3′ end of 16S rRNA

D. Court, X. Ji, S. Tarasov, 2011, Proceedings of the National Academy of Sciences.

Gateway vectors for the production of combinatorially‐tagged His6‐MBP fusion proteins in the cytoplasm and periplasm of Escherichia coli

D. Waugh, B. P. Austin, Kerri J. Penrose, 2005, Protein science : a publication of the Protein Society.

Balancing the production of two recombinant proteins in Escherichia coli by manipulating plasmid copy number: high-level expression of heterodimeric Ras farnesyltransferase.

D. Waugh, K. Tsao, 1997, Protein expression and purification.

Solution structure and functional analysis of the cysteine-rich C1 domain of kinase suppressor of Ras (KSR).

D. Morrison, R. Byrd, Ming Zhou, 2002, Journal of molecular biology.

The Ability to Enhance the Solubility of Its Fusion Partners Is an Intrinsic Property of Maltose-Binding Protein but Their Folding Is Either Spontaneous or Chaperone-Mediated

D. Waugh, S. Raran-Kurussi, 2012, PloS one.

Site-specific, enzymatic biotinylation of recombinant proteins in Spodoptera frugiperda cells using biotin acceptor peptides.

D. Waugh, K. Tsao, S. Duffy, 1998, Analytical biochemistry.

A versatile plasmid expression vector for the production of biotinylated proteins by site-specific, enzymatic modification in Escherichia coli.

H. Michel, D. Waugh, K. Tsao, 1996, Gene.

Phosphotyrosine Substrate Sequence Motifs for Dual Specificity Phosphatases

Sarah L. Keasey, Bryan M. Zhao, J. Tropea, 2015, PloS one.

Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate.

J. Tropea, D. Waugh, S. Cherry, 2015, Acta crystallographica. Section F, Structural biology communications.

Structural Basis for Oligosaccharide Recognition by Pyrococcus Furiosus Maltodextrin-binding Protein Protein Engineering Section Macromolecular Crystallography Laboratory

D. E. Anderson, K. M. Routzahn, D. Waugh, 2022 .

The Amino-terminal Domain of Human STAT4

R. Byrd, D. Waugh, S. Sarma, 1998, The Journal of Biological Chemistry.

High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design.

Bryan M. Zhao, D. Waugh, T. Burke, 2018, Acta crystallographica. Section D, Structural biology.

Tobacco Etch Virus Protease: Crystal Structure of the Active Enzyme and Its Inactive Mutant

A. Wlodawer, A. Zdanov, J. Tropea, 2003, Russian Journal of Bioorganic Chemistry.

Single amino acid substitutions on the surface of Escherichia coli maltose‐binding protein can have a profound impact on the solubility of fusion proteins

D. Waugh, R. Kapust, J. Fox, 2001, Protein science : a publication of the Protein Society.

Novel fold of VirA, a type III secretion system effector protein from Shigella flexneri

A. Wlodawer, Z. Dauter, J. Tropea, 2008, Protein science : a publication of the Protein Society.

Shigella flexneri Novel fold of VirA, a type III secretion system effector protein from

Z. Dauter, D. Waugh, Jamaine S. Davis, 2008 .

Electronic Reprint Biological Crystallography Structure of the N-terminal Domain of Yersinia Pestis Yoph at 2.0 ˚ a Resolution Biological Crystallography Structure of the N-terminal Domain of Yersinia Pestis Yoph at 2.0 a Ê Resolution

T. Copeland, J. Tropea, K. M. Routzahn, 2022 .

Structural characterization of the Yersinia pestis type III secretion system needle protein YscF in complex with its heterodimeric chaperone YscE/YscG

J. Tropea, D. Waugh, B. P. Austin, 2008, Journal of molecular biology.

Chemical shift assignments and folding topology of the Ras-binding domain of human Raf-1 as determined by heteronuclear three-dimensional NMR spectroscopy.

D. Fry, D. Waugh, J. Scheffler, 1994, Biochemistry.

Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.

Yue Li, Honggao Yan, J. Błaszczyk, 2007, Acta crystallographica. Section D, Biological crystallography.

Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain.

Zhen-Dan Shi, T. Burke, D. Waugh, 2005, Journal of molecular biology.

Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit.

D. E. Anderson, K. M. Routzahn, D. Waugh, 2001, Journal of molecular biology.

Structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas' disease.

J. Tropea, D. Waugh, G. Lountos, 2012, Molecular and biochemical parasitology.

Development of antiproliferative phenylmaleimides that activate the unfolded protein response.

A. Monks, C. Hose, M. Dyba, 2010, Bioorganic & medicinal chemistry.

A rapid oxime linker-based library approach to identification of bivalent inhibitors of the Yersinia pestis protein-tyrosine phosphatase, YopH.

Fa Liu, R. Hakami, D. Waugh, 2010, Bioorganic & medicinal chemistry letters.

Making the most of affinity tags.

D. Waugh, David S Waugh, 2005, Trends in biotechnology.

Crystal structure of plant aspartic proteinase prophytepsin: inactivation and vacuolar targeting

A Wlodawer, A. Wlodawer, A. Zdanov, 1999, The EMBO journal.

Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of the Yersinia pestis protein tyrosine phosphatase YopH.

D. Waugh, T. Burke, R. Ulrich, 2011, Acta crystallographica. Section D, Biological crystallography.

Structural biophysics of the NusB:NusE antitermination complex.

P. Wingfield, A. Altieri, Jess Li, 2008, Journal of molecular biology.

Complementation of an RNase P RNA (rnpB) gene deletion in Escherichia coli by homologous genes from distantly related eubacteria

N. Pace, D. Waugh, 1990, Journal of bacteriology.

Genetic tools for selective labeling of proteins with α-15N-amino acids

D. Waugh, 1996 .

Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites†

Y. Pommier, J. Tropea, D. Waugh, 2021, Chemical science.

Tripeptide inhibitors of Yersinia protein-tyrosine phosphatase.

T. Burke, Z. Yao, Zhon-Yin Zhang, 2003, Bioorganic & medicinal chemistry letters.

Structural enzymology and inhibition of the bi‐functional folate pathway enzyme HPPK–DHPS from the biowarfare agent Francisella tularensis

Yue Li, Honggao Yan, X. Ji, 2014, The FEBS journal.

Maltodextrin‐binding proteins from diverse bacteria and archaea are potent solubility enhancers

K. M. Routzahn, D. Waugh, J. Fox, 2003, FEBS letters.

Removal of Affinity Tags with TEV Protease.

D. Waugh, S. Cherry, S. Raran-Kurussi, 2017, Methods in molecular biology.

Matthew Pokross, J. Tropea, K. M. Routzahn, 2003, Nature Structural Biology.

Efficient site-specific processing of fusion proteins by tobacco vein mottling virus protease in vivo and in vitro.

T. Copeland, J. Tropea, D. Waugh, 2004, Protein expression and purification.

Structures of the Middle East respiratory syndrome coronavirus 3C‐like protease reveal insights into substrate specificity

D. Waugh, G. Lountos, D. Needle, 2015, Acta crystallographica. Section D, Biological crystallography.

Structure of human dual-specificity phosphatase 7, a potential cancer drug target.

J. Tropea, D. Waugh, B. P. Austin, 2015, Acta crystallographica. Section F, Structural biology communications.

Crystal structure of the human dual specificity phosphatase 1 catalytic domain

J. Tropea, D. Waugh, S. Cherry, 2018, Protein science : a publication of the Protein Society.

Selection and characterization of Yersinia pestis YopN mutants that constitutively block Yop secretion

G. Plano, D. Waugh, Franco Ferracci, 2005, Molecular microbiology.

Structural basis for binding of RNA and cofactor by a KsgA methyltransferase.

D. Court, X. Ji, J. Tropea, 2009, Structure.

Abstract A120: Cellular inhibition of Chk2 kinase and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019

Y. Pommier, A. Monks, R. Shoemaker, 2009 .

pathogenicity island protein IglCFrancisella tularensis New protein fold revealed by a 1 . 65 Å resolution crystal structure of

D. Waugh, B. P. Austin, F. Schubot, 2007 .

Structure of the cytoplasmic domain of Yersinia pestis YscD, an essential component of the type III secretion system.

J. Tropea, D. Waugh, G. Lountos, 2012, Acta crystallographica. Section D, Biological crystallography.

Atomic resolution structure of the cytoplasmic domain of Yersinia pestis YscU, a regulatory switch involved in type III secretion

D. Waugh, B. P. Austin, G. Lountos, 2009, Protein science : a publication of the Protein Society.

Electronic Reprint Biological Crystallography Differential Effects of Short Affinity Tags on the Crystallization of Pyrococcus Furiosus Maltodextrin-binding Protein Biological Crystallography Differential Effects of Short Affinity Tags on the Crystallization of Pyrococcus Furiosus Maltodextrin- Bind

D. Waugh, A. Evdokimov, M. Bucher, 2022 .

Author ' s personal copy Molecular cloning , overproduction , purification and biochemical characterization of the p 39 nsp 2 protease domains encoded by three alphaviruses

D. Waugh, J. Tözsér, Di Zhang, 2008 .

Targeting Protein-Protein Interactions of Tyrosine Phosphatases with Microarrayed Fragment Libraries Displayed on Phosphopeptide Substrate Scaffolds.

Bryan M. Zhao, J. Tropea, D. Waugh, 2019, ACS combinatorial science.

Electronic Reprint Biological Crystallography Three-dimensional Structure of the Type Iii Secretion Chaperone Syce from Yersinia Pestis Biological Crystallography Three-dimensional Structure of the Type Iii Secretion Chaperone Syce from Yersinia Pestis

J. Tropea, K. M. Routzahn, D. Waugh, 2022 .

High-resolution structure of the Yersinia pestis protein tyrosine phosphatase YopH in complex with a phosphotyrosyl mimetic-containing hexapeptide.

T. Burke, J. Tropea, D. Waugh, 2003, Biochemistry.

Crystal structures of MBP fusion proteins

D. Waugh, 2016, Protein science : a publication of the Protein Society.

Self-inhibited state of Venezuelan equine encephalitis virus (VEEV) nsP2 cysteine protease: a crystallographic and molecular dynamics analysis.

A. Wlodawer, D. Waugh, J. Tőzsér, 2023, Journal of molecular biology.

Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen

Michael S. Lee, D. Waugh, T. Kissner, 2015, Scientific Reports.

Novel Protein-Protein Interactions of the Yersinia pestis Type III Secretion System Elucidated with a Matrix Analysis by Surface Plasmon Resonance and Mass Spectrometry*

David S. Waugh, Robert G. Ulrich, W. Swietnicki, 2004, Journal of Biological Chemistry.

MBP-binding DARPins facilitate the crystallization of an MBP fusion protein

D. Waugh, G. Lountos, R. Gumpena, 2018, Acta crystallographica. Section F, Structural biology communications.

Isolation of Metarhizium anisopliae carboxypeptidase A with native disulfide bonds from the cytosol of Escherichia coli BL21(DE3).

D. Waugh, B. P. Austin, 2012, Protein expression and purification.

Protein Expression and Purification

Elsevier Sdol, J. Tropea, D. Waugh, 2009 .

Faculty Opinions recommendation of Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix.

D. Waugh, G. Lountos, 2020 .

Crystal structure of the protease‐resistant core domain of Yersinia pestis virulence factor YopR

J. Tropea, D. Waugh, B. P. Austin, 2005, Protein science : a publication of the Protein Society.

A Small-Molecule Microarray Approach for the Identification of E2 Enzyme Inhibitors in Ubiquitin-Like Conjugation Pathways

W. M. Hewitt, J. Tropea, D. Waugh, 2017, SLAS discovery : advancing life sciences R & D.

Genetic tools for selective labeling of proteins with alpha-15N-amino acids.

D. Waugh, 1996, Journal of biomolecular NMR.

Overproduction, purification, and biochemical characterization of the dual specificity H1 protein phosphatase encoded by variola major virus.

J. Tropea, D. Waugh, J. Phan, 2006, Protein expression and purification.

The Structure of V-Antigen, an Essential Virulence Factor and Mediator of Immunity against Plague

Z. Derewenda, A. Mateja, K. M. Routzahn, 2004 .

Structural basis for binding of RNA and cofactor by a KsgA methyltransferase.

D. Court, X. Ji, J. Tropea, 2009, Structure.

Structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas' disease.

J. Tropea, D. Waugh, G. Lountos, 2012, Molecular and biochemical parasitology.

Atomic resolution structure of the cytoplasmic domain of Yersinia pestis YscU, a regulatory switch involved in type III secretion

D. Waugh, B. P. Austin, G. Lountos, 2009, Protein science : a publication of the Protein Society.

Structural basis for oligosaccharide recognition by Pyrococcus furiosus maltodextrin-binding protein.

K. M. Routzahn, D. Waugh, A. Evdokimov, 2001, Journal of molecular biology.

Gap‐scan deletion analysis of Bacillus subtilis RNase P RNA

N. Pace, D. Waugh, 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Design of simplified ribonuclease P RNA by phylogenetic comparison.

N. Pace, D. Waugh, 1991, Methods in enzymology.

Structure of the POZ domain of human LRF, a master regulator of oncogenesis.

J. Tropea, D. Waugh, F. Schubot, 2006, Biochemical and biophysical research communications.

D. Waugh, S. Raran-Kurussi, 2014, Biotechnology and bioengineering.

Differential effects of supplementary affinity tags on the solubility of MBP fusion proteins

K. M. Routzahn, D. Waugh, 2004, Journal of Structural and Functional Genomics.

The high-precision solution structure of Yersinia modulating protein YmoA provides insight into interaction with H-NS.

A. Altieri, R. Byrd, J. Tropea, 2007, Biochemistry.