Jeongwu Lee

发表

microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma.

Yunqing Li, Howard Fine, Benjamin Purow, 2008, Cancer research.

Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation.

Q. Su, S. Pastorino, H. Fine, 2005, Cancer research.

Spatiotemporal Evolution of the Primary Glioblastoma Genome.

In-Hee Lee, Jinkuk Kim, Hee Jin Cho, 2015, Cancer cell.

THE FAS SYSTEM IS A KEY REGULATOR OF GERM CELL APOPTOSIS IN THE TESTIS

K. Boekelheide, J. Richburg, Jeongwu Lee, 1997 .

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines.

Yuri Kotliarov, Wei Zhang, Qin Su, 2006, Cancer cell.

Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth

Roger E. McLendon, Christine Eyler, Anita B. Hjelmeland, 2010, PLoS biology.

USP1 targeting impedes GBM growth by inhibiting stem cell maintenance and radioresistance.

D. Nam, Y. Shin, Jin-Ku Lee, 2016, Neuro-oncology.

Antitumor activity and prolonged expression from a TRAIL-expressing adenoviral vector.

H. Fine, P. Albert, Jeongwu Lee, 2002, Neoplasia.

ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.

Anne E Carpenter, Mark-Anthony Bray, Andrea Califano, 2014, Cell reports.

Notch-1 regulates transcription of the epidermal growth factor receptor through p53.

Q. Su, Y. Kotliarov, H. Fine, 2008, Carcinogenesis.

EZH 2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK / FOXM 1-Dependent Manner

Ichiro, K. Bhat, R. Ezhilarasan, 2014 .

Wnt / b -catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells

H. Seol, D. Nam, Jeongwu Lee, 2013 .

Tissue factor links inflammation, thrombosis, and senescence in COVID-19

Hye-Min Jeon, Jeongwu Lee, Dayna Nguyen, 2022, Scientific Reports.

ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages

A. Iavarone, D. Nam, Hyunggee Kim, 2020, Nature Communications.

Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2

J. Stamler, R. McLendon, S. Goldman, 2011, Cell.

Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3.

R. McLendon, Qiulian Wu, G. Stark, 2011, Cancer cell.

Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.

Emily J. Girard, Patrick J. Paddison, N. Baliga, 2015, Cell reports.

Neuronally expressed stem cell factor induces neural stem cell migration to areas of brain injury.

Lixin Sun, H. Fine, Jeongwu Lee, 2004, The Journal of clinical investigation.

The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors

Yunqing Li, Howard Fine, Benjamin Purow, 2009, The Journal of Neuroscience.

Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.

Emily J. Girard, J. Olson, J. Davison, 2013, Genes & development.

Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF 5 A

Emily J. Girard, J. Olson, J. Davison, 2013 .

Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha

I. Nakano, E. Sulman, M. Mayo, 2018, Neuro-oncology.

Transglutaminase 2 Inhibition Reverses Mesenchymal Transdifferentiation of Glioma Stem Cells by Regulating C/EBPβ Signaling.

D. Nam, I. Nakano, Seung-Hoon Lee, 2017, Cancer research.

CDK4/6 inhibition is more active against the glioblastoma proneural subtype.

Erik P. Sulman, Benjamin Purow, Ichiro Nakano, 2017, Oncotarget.

In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma

D. Nam, P. Paddison, Yeonghwan Kim, 2015, Oncotarget.

EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXM1-Dependent Manner

K. Bhat, R. Ezhilarasan, Kaushal Joshi, 2015, Stem cell reports.

Genome-wide CRISPR-Ca s 9 Screens Reveal Loss of Redundancy between PKMYT 1 and WEE 1 in Glioblastoma Stem-like Cells Graphical

Emily J. Girard, N. Baliga, J. Olson, 2015 .

Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ.

H. Woo, Jinkuk Kim, H. Seol, 2013, Cell reports.

MET signaling regulates glioblastoma stem cells.

H. Seol, Jung-Il Lee, D. Kong, 2012, Cancer research.

Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity.

Qiulian Wu, A. Sloan, R. Weil, 2012, Genes & development.

Tumor and Stem Cell Biology MET Signaling Regulates Glioblastoma Stem Cells

H. Seol, Jung-Il Lee, D. Kong, 2012 .

Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.

Yuri Kotliarov, Jean Claude Zenklusen, Wei Zhang, 2008, Cancer cell.

Targeting the epithelial to mesenchymal transition in glioblastoma: the emerging role of MET signaling

D. Nam, Jin-Ku Lee, Jeongwu Lee, 2014, OncoTargets and therapy.

Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy

Kyoung-Mee Kim, Raul Rabadan, Donggeon Kim, 2018, Nature Genetics.

Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells.

Jun Zhu, Ryan Basom, Do-Hyun Nam, 2013, Cancer discovery.

PIP4K2A as a negative regulator of PI3K in PTEN-deficient glioblastoma

Patrick J. Paddison, D. Nam, P. Paddison, 2019, The Journal of experimental medicine.

Modulation of Nogo receptor 1 expression orchestrates myelin-associated infiltration of glioblastoma.

A. Iavarone, D. Nam, H. Saya, 2021, Brain : a journal of neurology.

Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

H. Woo, R. Verhaak, M. Ceccarelli, 2020, Genome Biology.

Secretome analysis of patient-derived GBM tumor spheres identifies midkine as a potent therapeutic target

R. Rabadán, H. Seol, Jung-Il Lee, 2019, Experimental & Molecular Medicine.

Anti-SEMA3A Antibody: A Novel Therapeutic Agent to Suppress Glioblastoma Tumor Growth

D. Nam, Y. Shin, Jeongwu Lee, 2017, Cancer research and treatment : official journal of Korean Cancer Association.

Repurposing antipsychotics as glioblastoma therapeutics: Potentials and challenges.

D. Nam, Jin-Ku Lee, Jeongwu Lee, 2016, Oncology letters.

FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2

Hee Jin Cho, Do-Hyun Nam, Jung-Il Lee, 2015, PloS one.

Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells

I. Nakano, Hyunggee Kim, E. Hur, 2015, PLoS biology.

FoxM 1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox 2

Jung-Il Lee, D. Nam, Yeonghwan Kim, 2015 .

EphA2 Promotes Infiltrative Invasion of Glioma Stem Cells in vivo through Crosstalk with Akt and Regulates Stem Properties

A. Murphy, G. Yancopoulos, J. Rich, 2014, Oncogene.

Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells.

D. Nam, I. Nakano, J. Rich, 2013, Cancer cell.

Wnt/β-catenin signaling is a key downstream mediator of MET signaling in glioblastoma stem cells.

H. Seol, D. Nam, Jeongwu Lee, 2013, Neuro-oncology.

Wnt activation is implicated in glioblastoma radioresistance

Do-Hyun Nam, Heekyoung Yang, D. Nam, 2012, Laboratory Investigation.

Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion.

H. Fine, R. Jensen, Wei Zhang, 2011, Journal of the National Cancer Institute.

Targeting A 20 Decreases Glioma Stem Cell Survival and Tumor Growth

R. McLendon, Qiulian Wu, J. Rich, 2010 .

SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma.

H. Fine, D. Nam, M. Son, 2009, Cell stem cell.

Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation.

S. Pastorino, H. Fine, Wei Zhang, 2008, Cancer research.

WNT signaling in glioblastoma and therapeutic opportunities

D. Nam, Jin-Ku Lee, Jeongwu Lee, 2016, Laboratory Investigation.

Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma.

I. Nakano, T. Abbas, Breanna Brenneman, 2018, Cancer research.

MET: roles in epithelial-mesenchymal transition and cancer stemness.

Hye-Min Jeon, Jeongwu Lee, 2017, Annals of translational medicine.

Targetable T-type Calcium Channels Drive Glioblastoma.

E. Petricoin, D. Schiff, J. Wulfkuhle, 2017, Cancer research.

Downregulation of FIP200 Induces Apoptosis of Glioblastoma Cells and Microvascular Endothelial Cells by Enhancing Pyk2 Activity

R. Weil, Ping Huang, R. Prayson, 2011, PloS one.

Radiosensitization of brain metastasis by targeting c-MET

D. Nam, Yonghyun Kim, Jeongwu Lee, 2013, Laboratory Investigation.

Combined CDK4/6 and mTOR Inhibition Is Synergistic against Glioblastoma via Multiple Mechanisms

I. Nakano, T. Abbas, N. Leitinger, 2017, Clinical Cancer Research.

Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme

Hee Jin Cho, Do-Hyun Nam, D. Nam, 2015, Oncotarget.

Surface properties, more than size, limiting convective distribution of virus-sized particles and viruses in the central nervous system.

E. Oldfield, J. Hughes, Jeongwu Lee, 2005, Journal of neurosurgery.

Cellular and genetic characterization of human adult bone marrow-derived neural stem-like cells: a potential antiglioma cellular vector.

H. Fine, P. Albert, A. Elkahloun, 2003, Cancer research.

Antiglioma Cellular Vector Marrow-Derived Neural Stem-Like Cells : A Potential Cellular and Genetic Characterization of Human Adult Bone

H. Fine, P. Albert, A. Elkahloun, 2003 .

Dopamine receptor D2 regulates glioblastoma survival and death through MET and death receptor 4/5.

D. Nam, Hye-Min Jeon, J. Park, 2023, Neoplasia.

Proteasome-Mediated Destruction of the Cyclin A/Cyclin-Dependent Kinase 2 Complex Suppresses Tumor Cell Growth in Vitro and in Vivo

Steve Y. Cho, H. Fine, Wei Chen, 2004, Cancer Research.

ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages

A. Iavarone, D. Nam, Hyunggee Kim, 2020, Nature Communications.

Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

H. Woo, R. Verhaak, L. Cerulo, 2020, Genome Biology.

Statins affect human glioblastoma and other cancers through TGF-β inhibition

Benjamin Purow, Ichiro Nakano, Kazuo Shin-ya, 2019, Oncotarget.

Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling.

H. Fine, D. Nam, Hye-Min Jeon, 2023, Cancer cell.

The Fas system is a key regulator of germ cell apoptosis in the testis.

K. Boekelheide, J. Richburg, Jeongwu Lee, 1998, Endocrinology.

Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

Emily J. Girard, J. Olson, J. Davison, 2013 .

In vivo RNAi screen identifies NLK as a negative regulator of mesenchymal activity in glioblastoma

D. Nam, P. Paddison, Yeonghwan Kim, 2015, Oncotarget.

Bone marrow-derived, endothelial progenitor-like cells as angiogenesis-selective gene-targeting vectors

H. Fine, Jeongwu Lee, D. Kobiler, 2003, Gene Therapy.

Oncotargets and Therapy Dovepress Targeting the Epithelial to Mesenchymal Transition in Glioblastoma: the Emerging Role of Met Signaling

D. Nam, Jin-Ku Lee, Jeongwu Lee, 2022 .

Correction: Pigment Epithelium-Derived Factor (PEDF) Expression Induced by EGFRvIII Promotes Self-renewal and Tumor Progression of Glioma Stem Cells

I. Nakano, Hyunggee Kim, E. Hur, 2016, PLoS biology.